Evaluation of HLA in detection of non-parentage among known false trios.

Abstract:

:This paternity study was performed with trios in which the putative father was not the biological father (NBF), in order to evaluate the effectiveness of HLA-A and -B phenotyping for routine testing. All 372 generated trios had ABO, Rh, MNS, Kell, Duffy, Kidd and HLA (A and B) systems tested. HLA-A and -B phenotyping directly excluded 81.73% of NBF. Red blood cell markers excluded 8.82% of NBF missed by HLA; only 0.81% of NBF were not identified by the markers used. Each laboratory engaged in disputed paternity testing should evaluate its actual performance in detecting non-biological fathers and its exclusion rates in real trios. These data together can be used as a guide of mother's reliability.

journal_name

J Forensic Sci

authors

Salaru NN

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

1478-81

issue

6

eissn

0022-1198

issn

1556-4029

journal_volume

38

pub_type

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