Abstract:
:The sequences of the two hypervariable (HV) segments of the mitochondrial DNA (mtDNA) control region were determined in 167 randomly selected, unrelated individuals living in the state of Alagoas, north-eastern Brazil. One hundred and forty-five different haplotypes, associated with 139 variable positions, were determined. More than 95% of the mtDNA sequences could be allocated to specific mtDNA haplogroups according to the mutational motifs. Length heteroplasmy in the C-stretch HV1 and HV2 regions was observed in 22 and 11%, respectively, of the population sample. The genetic diversity was estimated to be 0.9975 and the probability of two random individuals presenting identical mtDNA haplotypes was 0.0084. The most frequent haplotype was shared by six individuals. All sequences showed high-quality values and phantom mutations were not detected. The diversity revealed in the mitochondrial control region indicates the importance of this locus for forensic casework and population studies within Alagoas, Brazil.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Barbosa AB,da Silva LA,Azevedo DA,Balbino VQ,Mauricio-da-Silva Ldoi
10.1111/j.1556-4029.2007.00619.xsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
142-6issue
1eissn
0022-1198issn
1556-4029pii
JFO619journal_volume
53pub_type
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