Abstract:
:Computer methods have been developed for mathematically interpreting mixed and low-template DNA. The genotype modeling approach computationally separates out the contributors to a mixture, with uncertainty represented through probability. Comparison of inferred genotypes calculates a likelihood ratio (LR), which measures identification information. This study statistically examined the genotype modeling performance of Cybergenetics TrueAllele(®) computer system. High- and low-template DNA mixtures of known randomized composition containing 2, 3, 4, and 5 contributors were tested. Sensitivity, specificity, and reproducibility were established through LR quantification in each of these eight groups. Covariance analysis found LR behavior to be relatively invariant to DNA amount or contributor number. Analysis of variance found that consistent solutions were produced, once a sufficient number of contributors were considered. This study demonstrates the reliability of TrueAllele interpretation on complex DNA mixtures of representative casework composition. The results can help predict an information outcome for a DNA mixture analysis.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Perlin MW,Hornyak JM,Sugimoto G,Miller KWdoi
10.1111/1556-4029.12788subject
Has Abstractpub_date
2015-07-01 00:00:00pages
857-68issue
4eissn
0022-1198issn
1556-4029journal_volume
60pub_type
杂志文章abstract::Human fetal skeletal elements of different gestational ages were screened with multiple mesh sizes (6.4 mm [1/4 inch], 3.2 mm [1/8 inch], 2.0 mm, and 1.0 mm) to determine their recovery rates. All remains were previously macerated, and no significantly damaged elements were used. The 6.4 mm mesh allowed a large loss o...
journal_title:Journal of forensic sciences
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doi:10.1111/1556-4029.12922
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journal_title:Journal of forensic sciences
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journal_title:Journal of forensic sciences
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journal_title:Journal of forensic sciences
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journal_title:Journal of forensic sciences
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2007.00548.x
更新日期:2007-11-01 00:00:00
abstract::The paper is concerned with the strength of DNA evidence when a suspect is identified via a search through a database of the DNA profiles of known individuals. Consideration of the appropriate likelihood ratio shows that in this setting the DNA evidence is (slightly) stronger than when a suspect is identified by other...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2010.01668.x
更新日期:2011-03-01 00:00:00
abstract::Radiographs of 277 living individuals were assessed via a numerical scoring system to determine the timing of appearance and degree of fusion between the proximal epiphysis of the fifth metatarsal and its diaphysis. The epiphysis was observed to first appear in females at 8 years and 10 years in males and fuse by 14 y...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12069
更新日期:2013-03-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2008.00902.x
更新日期:2009-01-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2010.01537.x
更新日期:2011-01-01 00:00:00
abstract::Gait is one biological characteristic which has attracted strong research interest due to its potential use in human identification. Although almost two decades have passed since a forensic gait expert has testified to the identity of a perpetrator in court, the methods remain insufficiently robust, considering the re...
journal_title:Journal of forensic sciences
pub_type: 杂志文章,评审
doi:10.1111/1556-4029.14036
更新日期:2019-09-01 00:00:00
abstract::This study evaluated the reliability of Widmark calculations, based on breath ethanol reading (BrACs), for estimating the amount of alcohol consumed. A standard ethanol dose (males 0.51 g/kg; females 0.43 g/kg) was given to 115 college seniors, and BrACs were measured for two hours. Calculations of ethanol dose were p...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::On September 10, 2003, Anna Lindh, the Swedish Minister for Foreign Affairs, was assassinated. The offender, a 24-year-old man, was a socially isolated, culturally and familially dislocated, yet academically quite competent young man who became enthralled with the habitual criminality of some of his relatives and thei...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2010.01653.x
更新日期:2011-03-01 00:00:00
abstract::This study examined the effects of fire on the features associated with saw marks in bone. Both class and individual characteristics were examined using stereomicroscopy and scanning electron microscopy (SEM). Twenty-four semifleshed Sus scrofa L. tibiae were sawed into three sections with the middle section having de...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12580
更新日期:2015-01-01 00:00:00
abstract::The diagnostic value of postmortem bacteriology has been discussed controversially for decades. In the study herein, contamination during sampling procedures and postmortem translocation were investigated to interpret postmortem microbiology results. One hundred medicolegal autopsy cases in total were included. Radiol...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12991
更新日期:2016-03-01 00:00:00
abstract::When determining an age estimate from adult skeletal remains, forensic anthropologists face a series of methodological choices. These decisions, such as which skeletal region to evaluate, which methods to apply, what statistical information to use, and how to combine information from multiple methods, ultimately impac...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2011.01979.x
更新日期:2012-03-01 00:00:00
abstract::The decomposition of bodies and the decay of associated cultural materials, including clothing, personal ornaments, caskets, and grave goods, was investigated based on a series of exhumations on a small sand island on Kwajalein Atoll, Marshall Islands. Decay data were documented for an interment period between 40 and ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract::Most studies of saw marks have focused on morphological characteristics and their utility in identifying saws suspected to have been utilized in cases of criminal dismemberment. The present study examined the extent to which metric analysis may be used to correlate saw blade measurements with minimum kerf widths (MKWs...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.14556
更新日期:2021-01-01 00:00:00
abstract::Identification of sex from skeleton parts is of paramount importance to medicolegal investigations. The present study makes an attempt to assess sex from the ulna by devising new measurements for fragmentary bones. Dry and adult ulnae (100 male and 60 female) of Madhya Pradesh, India were subjected to three measuremen...
journal_title:Journal of forensic sciences
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doi:
更新日期:2001-07-01 00:00:00
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journal_title:Journal of forensic sciences
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doi:
更新日期:2003-07-01 00:00:00
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journal_title:Journal of forensic sciences
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doi:
更新日期:2004-03-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::In the quest for a simple, reliable technique to estimate the sex of human remains several novel metric skeletal indices have been reported. Only a few have been examined for utility in populations different from those in which they were developed. In this study, the mastoid process was evaluated for sex determination...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12299
更新日期:2013-11-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12945
更新日期:2016-01-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2006.00224.x
更新日期:2006-09-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00