Abstract:
BACKGROUND:Opioid agonist therapy (OAT) models are generally provided without consideration of how pre-treatment characteristics may be associated with outcome. Therefore, we aimed to first characterize longitudinal trajectories of opioid use before initiating OAT. Then we explored the impact of OAT on opioid use across these pre-treatment trajectories. METHODS:Data were derived from three prospective cohort studies involving people who use drugs in Vancouver, Canada. Latent class growth analysis was applied to identify opioid use trajectories based on individual-level observations three years before starting OAT. Multivariable generalized linear mixed model was used to examine whether engaging in OAT was associated with lower risk of illicit opioid use among participants with different pre-treatment opioid use trajectories. RESULTS:464 participants were included in the study between September 2005 and November 2018. Two pre-treatment opioid use trajectories were identified: high frequency users (246, 53.0%) and gradually increasing frequency users (218, 47.0%). We observed different strengths of association between OAT engagement and illicit opioid use among high frequency users (adjusted odds ratio [AOR] = 0.36, 95% Confidence Interval [CI]: 0.20 - 0.63) and gradually increasing frequency users (AOR = 0.91, 95% CI: 0.53 - 1.56). Unstable housing, any stimulant use, experiencing violence, drug dealing, sex work involvement, and incarceration were independently and positively associated with ongoing illicit opioid use. CONCLUSIONS:Distinct pre-treatment opioid use trajectories are likely to influence treatment outcomes. Research is required to determine if tailored strategies specific to people with different pre-treatment opioid use patterns have potential to improve outcomes of OAT.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Dong H,Hayashi K,Fairbairn N,Milloy MJ,DeBeck K,Wood E,Kerr Tdoi
10.1016/j.addbeh.2020.106655subject
Has Abstractpub_date
2021-01-01 00:00:00pages
106655eissn
0306-4603issn
1873-6327pii
S0306-4603(20)30785-1journal_volume
112pub_type
杂志文章abstract::A staged model of smoking adoption has been widely applied in studies of adolescent smoking. The present study applied this model to examine the preliminary stages of tobacco and alcohol use by children. Using discriminant analysis, factors associated with the abstinence, initiation, and experimentation stages of toba...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(97)00005-1
更新日期:1997-09-01 00:00:00
abstract::Tobacco use is prevalent in adolescents and understanding factors that contribute to smoking uptake remains a critical public health priority. While there is now good support for the role of implicit (preconscious) cognitive processing in accounting for changes in drug use, these models have not been applied to tobacc...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2007.11.008
更新日期:2008-05-01 00:00:00
abstract::Thirty clients receiving Twelve-Step Facilitation Therapy in a rehabilitation setting formed the intervention group. They were asked to complete in third person a weekly evaluation of progress based on reading personal "Feelings" diaries they had written on a daily basis over a period of one week, starting 3weeks prev...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2006.05.011
更新日期:2007-02-01 00:00:00
abstract::The present study examined daughter and parent variables associated with bulimia nervosa, including attitudes about body image, eating and dieting histories, and self-esteem. Subjects were female undergraduates (bulimic, subclinical bulimic, and normal) their parents. Daughters differed in bodymass, with bulimics larg...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(95)00007-y
更新日期:1995-07-01 00:00:00
abstract::Three smoking cessation interventions designed for use by general practitioners (GPs) within the routine consultation were evaluated in a field setting using 26 GPs throughout metropolitan Sydney. A total of 450 smoking patients were allocated to either Structured Behavioral Change with nicotine gum (Group SBCN), Stru...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0306-4603(93)90049-f
更新日期:1993-03-01 00:00:00
abstract::This study was designed to investigate perceptions and metaperceptions of individuals in a mixed sex dating situation in which they were offered alcohol. Male and female participants who were unfamiliar with one another were brought together in individual sessions and asked to imagine that they were on a blind date. A...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(96)00065-2
更新日期:1997-09-01 00:00:00
abstract::When symptomatic individuals selectively attend to emotionally relevant stimuli, the ability to shift attention away from such material is impaired. Subjects may, however, seek to avoid further processing of these stimuli, which would facilitate attentional shifts. This was examined in a group of abstinent alcoholics'...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章
doi:10.1016/s0306-4603(96)00051-2
更新日期:1997-07-01 00:00:00
abstract::Smoking habits are continuously changing in the population. Cessation of smoking is not only often difficult but may lead to undesired consequences, esp. to weight gain. A random sample of 2283 persons with mild hypertension was followed up for 5 years in Eastern Finland and examined at the community-based cardiovascu...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(86)90002-x
更新日期:1986-01-01 00:00:00
abstract::Motivation or readiness to change has been studied intensively in recent years in research on the use of brief interventions to change alcohol problems in the primary care setting. The purpose of this study was to investigate the factor structure and concurrent and predictive evidence for validity of the short Stages ...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(99)00047-7
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:Specific events (e.g., Spring Break, holidays) are associated with greater college student drinking. However, the ways in which specific events are celebrated at specific campuses may impact students' beliefs about the social acceptability of drinking during these events, which may impact students' event-spec...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2015.01.033
更新日期:2015-06-01 00:00:00
abstract::The effect of an appointment-keeping intervention on attendance at aftercare was examined for 50 male participants in an inpatient alcohol treatment program. Subjects received either a calendar prompt and home-based attendance contract intervention (Experimental group, N = 25) or standard aftercare treatment arrangeme...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章
doi:10.1016/0306-4603(84)90010-8
更新日期:1984-01-01 00:00:00
abstract::This study determined whether adolescents in four stages of change provided significantly different ratings on evaluations of a tobacco awareness and cessation program and the program facilitators. A systematic sample of 639 adolescents in four stages of change (precontemplation, contemplation, preparation, and action...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(01)00265-9
更新日期:2003-04-01 00:00:00
abstract::To examine drinking problems and self concept of college students raised in homes where alcohol is abused, 148 lower division college students were given the following paper and pencil tests: The Michigan Alcoholism Screening Test, The Children of Alcoholics Screening Test, and the "Personal Self" section of The Tenne...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(89)90053-1
更新日期:1989-01-01 00:00:00
abstract::Smoking prevalence for those ages 45-65 is higher than the national average and the number of mid-life and older smokers is expected to increase as baby boomers age. Cessation, even after age 65, confers health benefits. Both physiologic and psychological mechanisms support use of physical activity (PA) as a coping to...
journal_title:Addictive behaviors
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.addbeh.2014.01.014
更新日期:2014-05-01 00:00:00
abstract::This study investigates the association linking truancy and drug-related experiences among adolescents surveyed via a street outreach program. A total of 2126 adolescents aged 12 to 18 years recruited from Taipei street sites completed a self-administered anonymous questionnaire. The lifetime prevalence of illicit dru...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2005.04.011
更新日期:2006-01-01 00:00:00
abstract::Previous studies have found that smoking is a strong factor that increases peripheral blood CD4+ T lymphocytes. However, most studies did not assess the cumulative long-life exposure of smoking on differential lymphocyte populations. In this study, to clarify the association of smoking habits and circulating lymphocyt...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2006.11.007
更新日期:2007-07-01 00:00:00
abstract::College students experience myriad negative consequences from alcohol misuse. The strength of the association between level of alcohol use and consequences may change across the initial years of college, as students develop tolerance or learn to avoid negative effects of drinking. Time varying effect models (TVEM) all...
journal_title:Addictive behaviors
pub_type: 杂志文章,多中心研究
doi:10.1016/j.addbeh.2017.04.022
更新日期:2017-10-01 00:00:00
abstract::Clients with severe mental illness and substance use disorder (i.e., dual disorders) frequently have contact with family members, who may provide valuable emotional and material support, but have limited skills and knowledge to promote recovery. Furthermore, high levels of family conflict and stress are related to hig...
journal_title:Addictive behaviors
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.addbeh.2009.03.025
更新日期:2009-10-01 00:00:00
abstract:INTRODUCTION:Tobacco use often starts in adolescence, yet assessment of dependence among adolescent smokers remains a challenge, particularly given the potential discord between self-reports of smoking behavior and actual use. We could find no prior study, among adolescents, that directly compares the association betwe...
journal_title:Addictive behaviors
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.addbeh.2010.06.013
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:The prevalence of electronic cigarette use has grown over the past decade, with some users reportedly initiating e-cigarette use primarily due to flavors. This study examined the role of flavors in initiation among adult e-cigarette users, as well as the association of flavors with satisfaction and perceived...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2019.106077
更新日期:2019-12-01 00:00:00
abstract::This preliminary study examined differences between cocaine-dependent pregnant women who received "baseline" drug treatment (N = 13) and those requiring additional "intensive" treatment (N = 9). Baseline drug treatment consisted of weekly individual counseling sessions. Intensive treatment, in the form of contingency ...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/0306-4603(94)90024-8
更新日期:1994-11-01 00:00:00
abstract::Compared to college women, college men face elevated risks for problematic drinking and negative alcohol-related consequences. These risks highlight the critical need to investigate gender issues and risk factors contributing to intoxication and related problems among men. Theoretical models suggest that conforming to...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2011.04.005
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Substance use disorders (SUD) represent one of the most important public health problems which has an onset in adolescence. Although substantial data exist on adolescent substance use, studies examining the role of parental psychopathological profiles on adolescent offspring SUD are lacking. Thus, this study...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2020.106611
更新日期:2021-01-01 00:00:00
abstract:INTRODUCTION:The CRAFFT questionnaire is a widely utilized measure of problematic alcohol and drug use. The brief screening instrument has been translated into multiple languages, and some studies regarding its psychometric properties have been published. However, investigations on the factorial validity of the CRAFFT ...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2016.03.020
更新日期:2016-08-01 00:00:00
abstract::If adolescents do not receive appropriate assistance in quitting smoking, they are highly likely to become regular smokers when they enter adulthood. Thus, an effective smoking-cessation program is required. A program was designed based on both the smoking-cessation barriers reported by students and effective strategi...
journal_title:Addictive behaviors
pub_type: 临床试验,杂志文章
doi:10.1016/j.addbeh.2014.05.009
更新日期:2014-10-01 00:00:00
abstract::Demographic factors, characteristics of military service, PTSD, and depression were examined as predictors of alcohol misuse in Iraq and Afghanistan War Veterans (N=287) presenting for post-deployment Veteran Affairs (VA) health care. Results indicated that alcohol misuse was more common among younger male Veterans wh...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2010.03.023
更新日期:2010-09-01 00:00:00
abstract::The possible impact of menstrual phase upon reactivity to nicotine was investigated in 12 healthy women smokers. Controlled doses of nicotine were administered via an intranasal aerosol delivery device to overnight-deprived women smokers in four hormonally verified menstrual phases. Physiological, biochemical, and sub...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(98)00033-1
更新日期:1999-01-01 00:00:00
abstract::A growing line of research has shown positive treatment outcomes from technology-based therapy for substance use disorders (SUDs). However, little is known about the effectiveness of technology-based SUD interventions for persons who already had numerous prior SUD treatments. We conducted a secondary analysis on a 12-...
journal_title:Addictive behaviors
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.addbeh.2015.11.009
更新日期:2016-03-01 00:00:00
abstract::The purpose of this study was to identify cultural, social, and intrapersonal factors associated with tobacco, alcohol, and illicit drug use among students attending dropout prevention/recovery high schools. Four mutually exclusive categories of substance use were used as outcome measures, and religiosity, educational...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/s0306-4603(99)00006-4
更新日期:2000-01-01 00:00:00
abstract::This trial of cognitive-behavioural therapy (CBT) based amphetamine abstinence program (n=507) focused on refusal self-efficacy, improved coping, improved problem solving and planning for relapse prevention. Measures included the Severity of Dependence Scale (SDS), the General Health Questionnaire-28 (GHQ-28) and Amph...
journal_title:Addictive behaviors
pub_type: 杂志文章
doi:10.1016/j.addbeh.2005.12.026
更新日期:2006-10-01 00:00:00