The impact of chronic obstructive pulmonary disease on hospitalization and mortality in patients with heart failure.

abstract：OBJECTIVE:The aim of this study was to evaluate the significance of the development of a restrictive response to an acute saline load, defined as an increase in the ratio of peak early to peak late diastolic transmitral flow velocity (E/A ratio) associated with a decrease in the deceleration time, in patients with mild...

journal_title：European journal of clinical investigation

authors： Triposkiadis F,Moyssakis I,Makris T,Hatzizaharias A,Hadjinikolaou L,Kyriakidis M

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:The ratio of serum C-reactive protein (CRP) to albumin has been proven to be a more accurate indicator than albumin and CRP levels alone in determining the prognosis of patients with cancer and critical illness. The aim of this study was to determine whether the CRP/albumin ratio (CAR) can be linked to imper...

journal_title：European journal of clinical investigation

authors： Karabağ Y,Çağdaş M,Rencuzogullari I,Karakoyun S,Artaç İ,İliş D,Yesin M,Çağdaş ÖS,Altıntaş B,Burak C,Tanboğa HI

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Smoking remains the most important avoidable cause of global mortality. Even though the number of cigarette smokers declines in first world countries, the uses of alternative nicotine delivery products increase and may even surpass the sells of cigarettes. In this light, the explicit role of nicotine in the ...

journal_title：European journal of clinical investigation

authors： Babic M,Schuchardt M,Tölle M,van der Giet M

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Topoisomerase IIα (topo IIα) protein expression has prognostic significance in many cancers. However, it is still unclear whether topo IIα protein expression and gene alterations play roles as prognostic factors in diffuse large B-cell lymphoma (DLBCL). MATERIALS AND METHODS:We selected 102 patients with DL...

journal_title：European journal of clinical investigation

authors： Chen Z,Wang J,Zhang H,Liu D,Li Y,Xu Y,Tan D,Chen D,Zhao X,Wang G

更新日期：2012-03-01 00:00:00

abstract：:In order to study the mechanisms by which nutrients influence post-trauma metabolism, Sprague-Dawley rats received a 25% full-thickness burn and were randomly assigned to receive 12.5 g kg-1 bodyweight (BW) per day amino acids (AA) only, AA and 14.7 g hydrous glucose kg-1 BW per day or AA and 14.7 g hydrous xylitol kg...

journal_title：European journal of clinical investigation

authors： Georgieff M,Pscheidl E,Moldawer LL,Bistrian BR,Blackburn GL

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:We recently reported high high-density lipoprotein (HDL) cholesterol as a predictor of recurrent risk in a subgroup of postinfarction patients defined by hypercholesterolemia and high C-reactive protein (CRP) levels. We investigated whether a similar high-risk subgroup might exist for incident cardiovascular...

journal_title：European journal of clinical investigation

authors： Corsetti JP,Gansevoort RT,Sparks CE,Dullaart RP

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Insulin resistance significantly correlated with a non-dipper type of essential hypertension. Thiazolidinediones (TZD), oral hypoglycaemic agents that act as insulin sensitizers, have been demonstrated in multiple in vivo and in vitro studies to possess antihypertensive properties. This study examined the ef...

journal_title：European journal of clinical investigation

authors： Anan F,Masaki T,Fukunaga N,Teshima Y,Iwao T,Kaneda K,Umeno Y,Okada K,Wakasugi K,Yonemochi H,Eshima N,Saikawa T,Yoshimatsu H

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Cancer is often caused by disturbance in the regulation and/or execution of programmed cell death (PCD, including apoptosis and autophagy). Our aim was to investigate these two pathways simultaneously in the same samples to understand further the pathological roles of PCDs in colorectal cancer. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Chang YT,Tseng HC,Huang CC,Chen YP,Chiang HC,Chou FP

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The DALI low-density lipoprotein (LDL) apheresis system is the first whole-blood apheresis system in regular clinical use. DALI stands for direct adsorption of lipoproteins, which describes the basic principle of operation of this newly developed LDL apheresis procedure. METHODS:The selective removal of LDL...

journal_title：European journal of clinical investigation

authors： Dräger LJ,Julius U,Kraenzle K,Schaper J,Toepfer M,Zygan K,Otto V,Steinhagen-Thiessen E

更新日期：1998-12-01 00:00:00

abstract：:Adequate pregnancy care of women with systemic lupus erythematosus (SLE) rests on three pillars: a coordinated medical-obstetrical care, an agreed and well-defined management protocol and a good neonatal unit. Pregnancy should be planned following a preconceptional visit for counselling. Women with severe active disea...

journal_title：European journal of clinical investigation

authors： Ruiz-Irastorza G,Khamashta MA

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:obesity-related microvascular dysfunction, including alterations in rhythmic changes in vascular diameter, so-called 'vasomotion', may be important in the clustering of obesity with other cardiovascular risk factors. Adipokines have been suggested to play a role in obesity-related vascular dysfunction. Altera...

journal_title：European journal of clinical investigation

authors： de Boer MP,Wijnstok NJ,Serné EH,Eringa EC,Stehouwer CD,Flyvbjerg A,Hoekstra T,Heymans MW,Meijer RI,Twisk JW,Smulders YM

更新日期：2014-07-01 00:00:00

abstract：:A haemolytically inactive alpha-mobile complement C8 component was identified by crossed immunoelectrophoresis in a 27-year-old male with recurrent meningococcal infections and absence of complement mediated serum haemolytic activity. The patient's serum/plasma contained no demonstrable normal C8. C8 inhibitor activit...

journal_title：European journal of clinical investigation

authors： Brandslund I,Teisner B,Strate M,Grunnet N,Svehag SE,Isager H,Wang P

更新日期：1983-04-01 00:00:00

abstract：:There is considerable information to indicate that when there is vessel injury, platelets can play a major role in the development of atherosclerosis and its thromboembolic complications in the non-diabetic population. Diabetes is a disease associated with an increased risk of vascular complications, but the nature of...

journal_title：European journal of clinical investigation

authors： Winocour PD

更新日期：1994-02-01 00:00:00

abstract：:To assess the degree of immune system activation associated with addiction or hepatotropic viruses infection, we examined 60 HIV-negative heroin addicts for the presence of hepatitis B virus (HBV) infection markers, hepatitis C virus antibodies (anti-HCV), various auto-antibodies, and serum levels of soluble interleuk...

journal_title：European journal of clinical investigation

authors： Dalekos GN,Manoussakis MN,Zervou E,Tsianos EV,Moutsopoulos HM

更新日期：1993-04-01 00:00:00

abstract：:In search of new practical diagnostic methods for the early diagnosis of hereditary medullary carcinoma of the thyroid (MCT) calcitonin release has been studied following induction by pentagastrin, cholecystokinin-pancreozymin (the C-terminal octapeptide, C8-CCK, and the native swine extract), and ethanol in eighteen ...

journal_title：European journal of clinical investigation

authors： Telenius-Berg M,Almqvist S,Berg B,Hedner P,Ingemansson S,Tibblin S,Wasthed B

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:The accuracy of estimating glomerular filtration rate from plasma creatinine (eGFR) has been questioned but it is unclear how much covert error in several reference methods that have been used has contributed to this perceived inaccuracy. The aim of the study was to evaluate eGFR in comparison with a second ...

journal_title：European journal of clinical investigation

authors： Bird NJ,Peters C,Michell AR,Peters AM

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Several studies have reported a significant gender difference in low-density lipoprotein (LDL) size, with men being characterized by smaller, denser LDL particles than women, and it has been suggested that the contribution of the greater accumulation of visceral adipose tissue in men compared with women may ...

journal_title：European journal of clinical investigation

authors： Lemieux I,Pascot A,Lamarche B,Prud'homme D,Nadeau A,Bergeron J,Després JP

更新日期：2002-12-01 00:00:00

abstract：:Flow cytometry was used to study phagocytic function and release of reactive oxygen intermediates (ROI) following phagocytosis by granulocytes in 14 patients (six female, eight male) with gram-negative septicaemia prior to, during, and after therapy compared with a group of healthy controls. Phagocytic capacity was as...

journal_title：European journal of clinical investigation

authors： Wenisch C,Parschalk P,Hasenhündl M,Griesmacher A,Graninger W

更新日期：1995-06-01 00:00:00

abstract：:Disseminated intravascular coagulation (DIC) is a frequently occurring complication of sepsis and may contribute to multiple organ failure. More insight into the pathogenesis of this derangement of the coagulation system is necessary to develop more effective therapeutic strategies for this condition. Recently, more d...

journal_title：European journal of clinical investigation

authors： Levi M,van der Poll T,ten Cate H,van Deventer SJ

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:We aimed to analyse the pre-analytical process and its effect of 50 g of oral glucose challenge test results for screening gestational diabetes mellitus. RESEARCH DESIGN AND METHODS:The 50 g oral glucose challenge test was performed to 30 pregnant women, and the blood was collected as two samples for three t...

journal_title：European journal of clinical investigation

authors： Eldem S,Oskovi-Kaplan ZA,Engin-Ustun Y,Yilmaz C,Caglar AT,Ozgu-Erdinc AS

更新日期：2020-12-22 00:00:00

abstract：:Whether leptin levels are related to insulin sensitivity or subject to acute regulation by insulin is not known. In 12 obese [body mass index (BMI) = 34.0 +/- 1.5 kg m-2] and 12 lean (BMI = 22.2 +/- 0.6 kg m-2) non-diabetic subjects, plasma leptin concentrations were measured in the fasting state and during 2 hours of...

journal_title：European journal of clinical investigation

authors： Muscelli E,Camastra S,Masoni A,Baldi S,Sironi AM,Natali A,Ferrannini E

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Predictors of gingival enlargement in patients treated with anti-epileptics have not been previously assessed. This study was conducted to determine, with the aid of two indices that score vertical and horizontal overgrowth, the prevalence and risk factors for gingival enlargement in patients treated with ph...

journal_title：European journal of clinical investigation

authors： Brunet L,Miranda J,Roset P,Berini L,Farré M,Mendieta C

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Na+,K(+)-ATPase activity was evaluated in relation to membrane composition and molecular organization in erythrocyte membranes from obese patients by the amphyphylic molecule 6-dodecanoyl-2-dimethylamino-naphthalene (Laurdan). Its possible relationship with fat distribution and hyperinsulinaemia was also inv...

journal_title：European journal of clinical investigation

authors： Faloia E,Garrapa GG,Martarelli D,Camilloni MA,Lucarelli G,Staffolani R,Mantero F,Curatola G,Mazzanti L

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Metastatic pheochromocytomas (PCs) and paragangliomas (PGLs) are rare neuroendocrine tumours with a strong genetic background. DESIGN:We searched the PubMed database through February 2015 to identify studies characterizing metastatic PCs/PGLs as well as currently established and evolving therapies. RESULTS...

journal_title：European journal of clinical investigation

authors： Angelousi A,Kassi E,Zografos G,Kaltsas G

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:There is an ongoing debate on a potential protective role of habitual physical activity and passive heat therapy on the risk of COVID-19, a respiratory infectious disease that can manifest as severe pneumonia. To explore these putative roles, we evaluated the independent and joint associations of cardiorespi...

journal_title：European journal of clinical investigation

authors： Kunutsor SK,Laukkanen JA

更新日期：2021-01-10 00:00:00

abstract：BACKGROUND:A high pulse pressure (PP) is associated with adverse cardiovascular (CV) outcomes; however, this relationship may be reversed in patients with heart failure with reduced ejection fraction (HFREF). METHODS:Patients from the WARCEF trial with left ventricular ejection fraction ≤35% were included. PP was divi...

journal_title：European journal of clinical investigation

authors： Shah N,Qian M,Di Tullio MR,Graham S,Mann DL,Sacco RL,Lip GYH,Labovitz AJ,Ponikowski P,Lok DJ,Anker SD,Teerlink JR,Thompson JLP,Homma S,Freudenberger RS,WARCEF Investigators.

更新日期：2019-02-23 00:00:00

abstract：BACKGROUND:An earlier report described that transgenic mice ubiquitously expressing cryptochrome1 (CRY1) with a mutation in cystein414 (CRY1-AP Tg mice) display diabetes mellitus in addition to anomalous circadian behaviours. This study examined characteristic aspects of symptoms to clarify the diabetes type and pathog...

journal_title：European journal of clinical investigation

authors： Okano S,Hayasaka K,Igarashi M,Iwai H,Togashi Y,Nakajima O

更新日期：2010-11-01 00:00:00

abstract：:Insulin resistance has been reported in normal ageing but discrepancies between such studies may be related to compounding factors such as body composition and exercise patterns. We employed a two-step hyperinsulinaemic euglycaemic clamp to assess peripheral and hepatic tissue insulin sensitivity and glucose recycling...

journal_title：European journal of clinical investigation

authors： Broughton DL,James OW,Alberti KG,Taylor R

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Linear growth restriction is a unique feature of paediatric inflammatory bowel diseases (IBD), and reduced insulin-like growth factor (IGF-1) is a major determinant of short stature. We aimed to assess factors influencing somatic height in children suffering from IBD. MATERIALS AND METHODS:This was a retros...

journal_title：European journal of clinical investigation

authors： Chouliaras G,Mantzou A,Margoni D,Tsilifis N,Pervanidou P,Panayotou I,Kanaka-Gantenbein C,Chrousos GP,Roma-Giannikou E

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:We have investigated the potential for using antisense technology as a means of delivering treatment for acute myeloblastic leukaemia (FAB-M2) by gene therapy. MATERIALS AND METHODS:A test recombinant adenovirus vector was constructed containing human c-myc antisense fragments to study the effects of alteri...

journal_title：European journal of clinical investigation

authors： Chen JP,Chen L,Leek J,Lin C

更新日期：2006-01-01 00:00:00