Abstract：
:In domesticated strains of the Nile tilapia, phenotypic sex has been linked to genetic variants on linkage groups 1, 20 and 23. This diversity of sex-loci might reflect a naturally polymorphic sex determination system in Nile tilapia, or it might be an artefact arising from the process of domestication. Here, we searched for sex-determiners in wild populations from Kpandu, Lake Volta (Ghana-West Africa), and from Lake Koka (Ethiopia-East Africa) that have not been subjected to any genetic manipulation. We analysed lab-reared families using double-digest Restriction Associated DNA sequencing (ddRAD) and analysed wild-caught males and females with pooled whole-genome sequencing (WGS). Strong sex-linked signals were found on LG23 in both populations, and sex-linked signals with LG3 were observed in Kpandu samples. WGS uncovered blocks of high sequence coverage, suggesting the presence of B chromosomes. We confirmed the existence of a tandem amh duplication in LG23 in both populations and determined its breakpoints between the oaz1 and dot1l genes. We found two common deletions of ~5 kb in males and confirmed the presence of both amhY and amh∆Y genes. Males from Lake Koka lack both the previously reported 234 bp deletion and the 5 bp frameshift-insertion that creates a premature stop codon in amh∆Y.
journal_name
Genes (Basel)journal_title
Genesauthors
Triay C,Conte MA,Baroiller JF,Bezault E,Clark FE,Penman DJ,Kocher TD,D'Cotta Hdoi
10.3390/genes11091017subject
Has Abstractpub_date
2020-08-29 00:00:00issue
9issn
2073-4425pii
genes11091017journal_volume
11pub_type
杂志文章相关文献
Genes文献大全abstract：:Porcine epidemic diarrhea (PED) is a major gastrointestinal disease afflicting suckling pigs that causes huge industrial economic losses. In this study, we investigated microbiota from the colonic mucosa and content in healthy and PED piglets. High-throughput 16S rRNA gene sequencing was performed to identify inter-gr...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes11010044
更新日期：2019-12-30 00:00:00
abstract：:Each domestic dog breed is characterized by a strict set of physical and behavioral characteristics by which breed members are judged and rewarded in conformation shows. One defining feature of particular interest is the coat, which is comprised of either a double- or single-layer of hair. The top coat contains coarse...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes10050323
更新日期：2019-04-26 00:00:00
abstract：:Vavilovia formosa is a relict leguminous plant growing in hard-to-reach habitats in the rocky highlands of the Caucasus and Middle East, and it is considered as the putative closest living relative of the last common ancestor (LCA) of the Fabeae tribe. Symbionts of Vavilovia belonging to Rhizobium leguminosarum bv. vi...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes10120990
更新日期：2019-12-01 00:00:00
abstract：:Warmblood fragile foal syndrome (WFFS) is an autosomal recessive disorder caused by a single nucleotide variant in the procollagen-lysine-2-oxoglutarate-5-dioxygenase 1 gene (PLOD1:c.2032G>A, p.Gly678Arg). Homozygosity for the PLOD1 variant causes an Ehler-Danlos-like syndrome, which has to date only been reported in ...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes11121518
更新日期：2020-12-18 00:00:00
abstract：:Osteoarthritis (OA) is a widely prevalent disease worldwide, and with an increasingly ageing society, it has become a challenge for the field of regenerative medicine. OA is a disease process involving multiple joint tissues, including those not visible on radiography, and is a complex disease process with multiple ph...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes10121051
更新日期：2019-12-17 00:00:00
abstract：:Telomeric repeats, coated by the shelterin complex, prevent inappropriate activation of the DNA damage response at the ends of linear chromosomes. Shelterin has evolved distinct solutions to protect telomeres from different aspects of the DNA damage response. These solutions include formation of t-loops, which can seq...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes10040318
更新日期：2019-04-24 00:00:00
abstract：:GOLDEN2-LIKE (GLK) is a member of the myeloblastosis (MYB) family transcription factor and it plays an important role in the regulation of plastid development and stress tolerance. In this study, a gene named AhGLK1b was identified from a cultivated peanut showing down-regulation in response to low calcium with a comp...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes11030343
更新日期：2020-03-24 00:00:00
abstract：:Despite a considerable body of published research on hepatitis B in Bangladesh, researchers continue to lament the lack of reliable information about hepatitis B virus (HBV) infection epidemiology. The present review aims to provide a comprehensive survey of the literature with particular focus on a number of epidemio...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes9110541
更新日期：2018-11-08 00:00:00
abstract：:Lysosomal storage disorders (LSDs) represent a group of more than 50 severe metabolic diseases caused by the deficiency of specific lysosomal hydrolases, activators, carriers, or lysosomal integral membrane proteins, leading to the abnormal accumulation of substrates within the lysosomes. Numerous mutations have been ...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes9020073
更新日期：2018-02-06 00:00:00
abstract：:Almost all eukaryotes have transposable elements (TEs) against which they have developed defense mechanisms. In the Drosophila germline, the main transposable element (TE) regulation pathway is mediated by specific Piwi-interacting small RNAs (piRNAs). Nonetheless, for unknown reasons, TEs sometimes escape cellular co...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes11020215
更新日期：2020-02-19 00:00:00
abstract：:MDM4, an essential negative regulator of the P53 tumor suppressor, is frequently overexpressed in cancer cells that harbor a wild-type P53. By a mechanism based on alternative splicing, the MDM4 gene generates two mutually exclusive isoforms: MDM4-FL, which encodes the full-length MDM4 protein, and a shorter splice va...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes8020082
更新日期：2017-02-20 00:00:00
abstract：:White spot syndrome virus (WSSV), the lone virus of the genus Whispovirus under the family Nimaviridae, is one of the most devastating viruses affecting the shrimp farming industry. Knowledge about this virus, in particular, its evolution history, has been limited, partly due to its large genome and the lack of other ...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes11010094
更新日期：2020-01-14 00:00:00
abstract：:The increasing availability of large-scale time series data allows the inference of microbial community dynamics by association network analysis. However, correlation-based association network analyses are noninformative of causal, mediating and time-dependent relationships between microbial community functional facto...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes10030216
更新日期：2019-03-14 00:00:00
abstract：:Accurate species identification from ancient DNA samples is a difficult task that would shed light on the evolutionary history of pathogenic microorganisms. The field of palaeomicrobiology has undoubtedly benefited from the advent of untargeted metagenomic approaches that use next-generation sequencing methodologies. ...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes9080418
更新日期：2018-08-20 00:00:00
abstract：:The nitrogen use efficiency (NUE) of crop plants is limited and enhancing it in rice, a major cereal crop, would be beneficial for farmers and the environment alike. Here we report the genome-wide transcriptome analysis of two rice genotypes, IR 64 (IR64) and Nagina 22 (N22) under optimal (+N) and chronic starvation (...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes9040206
更新日期：2018-04-11 00:00:00
abstract：:Fruit set is the earliest phase of fruit growth and represents the onset of ovary growth after successful fertilization. In parthenocarpy, fruit formation is less affected by environmental factors because it occurs in the absence of pollination and fertilization, making parthenocarpy a highly desired agronomic trait. ...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes11121441
更新日期：2020-11-30 00:00:00
abstract：:Yersinia enterocolitica is the causative agent of yersiniosis, a zoonotic disease of growing epidemiological importance with significant consequences for public health. This pathogenic species has been intensively studied for many years. Six biotypes (1A, 1B, 2, 3, 4, 5) and more than 70 serotypes of Y. enterocolitica...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes9050235
更新日期：2018-05-03 00:00:00
abstract：:Marek's Disease is a lymphoproliferative disease of chickens caused by Marek's Disease Virus. Similar to other herpesviruses, Marek's Disease Virus (MDV) encodes its own small non-coding regulatory RNAs termed microRNAs (miRNAs). We previously found that the expression profile of these viral miRNAs is affected by vacc...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes10020115
更新日期：2019-02-05 00:00:00
abstract：:MicroRNAs (miRNAs) are short, single-stranded, non-coding RNA molecules that act as post-transcriptional gene regulators. They can inhibit target protein-coding genes, through repressing messenger RNA (mRNA) translation or promoting their degradation. miRNAs were initially found to be originated from nuclear genome an...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes5040865
更新日期：2014-09-26 00:00:00
abstract：:While methods for detecting SNVs and indels in circulating tumor DNA (ctDNA) with hybridization capture-based next-generation sequencing (NGS) have been available, copy number variations (CNVs) detection is more challenging. Here, we present a method enabling CNV detection from a 150-gene panel using a very low amount...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes10110926
更新日期：2019-11-14 00:00:00
abstract：:We employed Illumina 450 K Infinium microarrays to profile DNA methylation (DNAm) in neuronal nuclei separated by fluorescence-activated sorting from the postmortem orbitofrontal cortex (OFC) of heroin users who died from heroin overdose (N = 37), suicide completers (N = 22) with no evidence of heroin use and from con...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes8060152
更新日期：2017-05-30 00:00:00
abstract：:Epigenetic alterations at imprinted genes on different chromosomes have been linked to several imprinting disorders (IDs) such as Beckwith-Wiedemann syndrome (BWS) and pseudohypoparathyroidism type 1b (PHP1b). Here, we present a male patient with these two distinct IDs caused by two independent mechanisms-loss of meth...
journal_title：Genes
pub_type：
doi：10.3390/genes12020172
更新日期：2021-01-27 00:00:00
abstract：:One of the hallmarks of cancer cells is their indefinite replicative potential, made possible by the activation of a telomere maintenance mechanism (TMM). The majority of cancers reactivate the reverse transcriptase, telomerase, to maintain their telomere length but a minority (10% to 15%) utilize an alternative lengt...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes11020133
更新日期：2020-01-27 00:00:00
abstract：:This study investigated the effects of dietary terrestrial animal and plant proteins on the intestinal transcriptomes of yellowtail kingfish (YTK), Seriola lalandi, an ecologically and economically important marine species in Australia. Five diets containing fish meal (FM), poultry by-product meal (PBM), blood meal (B...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes11060621
更新日期：2020-06-05 00:00:00
abstract：:microRNA (miRNA) activity and regulation are of increasing interest as new therapeutic targets. Traditional approaches to assess miRNA levels in cells rely on RNA sequencing or quantitative PCR. While useful, these approaches are based on RNA extraction and cannot be applied in real-time to observe miRNA activity with...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes9060305
更新日期：2018-06-19 00:00:00
abstract：:DNA Helicase B (HELB) is a conserved helicase in higher eukaryotes with roles in the initiation of DNA replication and in the DNA damage and replication stress responses. HELB is a predominately nuclear protein in G1 phase where it is involved in initiation of DNA replication through interactions with DNA topoisomeras...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes11050578
更新日期：2020-05-21 00:00:00
abstract：:The Himalayas are one of earth's hotspots of biodiversity. Among its many cryptic and undiscovered organisms, including vertebrates, this complex high-mountain ecosystem is expected to harbour many species with adaptations to life in high altitudes. However, modern evolutionary genomic studies in Himalayan vertebrates...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes10110873
更新日期：2019-10-31 00:00:00
abstract：:The Mexican population has one of the highest prevalences of metabolic syndrome (MetS) worldwide. The aim of this study was to investigate the association of single-nucleotide polymorphisms (SNPs) with MetS and its components. First, we performed a pilot Genome-wide association study (GWAS) scan on a sub-sample derive...
journal_title：Genes
pub_type： 杂志文章
doi：10.3390/genes11101192
更新日期：2020-10-14 00:00:00
abstract：:Background: Congenital disorder of glycosylation (CDG) is a severe morphogenic and metabolic disorder that affects all of the systems of organs and is caused by a mutation of the gene PMM2, having a mortality rate of 20% during the first months of life. Results: Here we report the outcome of an in vitro fertilisation ...
journal_title：Genes
pub_type：
doi：10.3390/genes11060697
更新日期：2020-06-25 00:00:00
abstract：:Despite worldwide prevention programs, the incidence for cutaneous melanoma is continuously increasing. Mucosal melanoma (MM) represents a rare but highly aggressive phenotype of common melanoma with predilection in the sinonasal system. Far away from ultraviolet sun exposure, the molecular mechanisms underlying tumor...
journal_title：Genes
pub_type： 杂志文章,评审
doi：10.3390/genes8120384
更新日期：2017-12-13 00:00:00
