Abstract:
BACKGROUND:G-protein subunit beta 1 like (GNB1L) encodes a G-protein beta-subunit-like polypeptide. Chicken GNB1L is upregulated in the breast muscle of high feed efficiency chickens, and its expression is 1.52-fold that in low feed efficiency chickens. However, no report has described the effects of GNB1L indels on the chicken carcass and growth traits. RESULTS:This study identified a 31-bp indel in the 5' untranslated region (UTR) of GNB1L and elucidated the effect of this gene mutation on the carcass and growth traits in chickens. The 31-bp indel showed a highly significant association with the body weight at 8 different stages and was significantly correlated with daily gains at 0 to 4 weeks and 4 to 8 weeks. Similarly, the mutation was significantly associated with small intestine length, breast width, breast depth and breast muscle weight. Moreover, DD and ID were superior genotypes for chicken growth and carcass traits. CONCLUSIONS:These results show that the 31-bp indel of GNB1L significantly affects chicken body weight and carcass traits and can serve as a candidate molecular marker for chicken genetics and breeding programs.
journal_name
BMC Genetjournal_title
BMC geneticsauthors
Ren T,Yang Y,Lin W,Li W,Xian M,Fu R,Zhang Z,Mo G,Luo W,Zhang Xdoi
10.1186/s12863-020-00900-zsubject
Has Abstractpub_date
2020-08-26 00:00:00pages
91issue
1issn
1471-2156pii
10.1186/s12863-020-00900-zjournal_volume
21pub_type
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