Characterization of the Esophageal Microbiota and Prediction of the Metabolic Pathways Involved in Esophageal Cancer.

abstract：:Invasive aspergillosis (IA) is a deep tissue infection with a high mortality occurring mostly in immunocompromised patients. To investigate the pathology of patients with IA it may be important to determine the genotype of the invasive isolate of Aspergillus, however available tissues for study are often formalin fixe...

journal_title：Frontiers in cellular and infection microbiology

authors： de Groot T,Hagen F,Vreuls W,Verweij PE,Chowdhary A,Meis JF

更新日期：2018-10-23 00:00:00

abstract：:Burkholderia pseudomallei is the causative agent of melioidosis, a rare disease of biodefense concern with high mortality and extreme difficulty in treatment. No human vaccines are available that protect against B. pseudomallei infection, and with the current limitations of antibiotic treatment, the development of new...

journal_title：Frontiers in cellular and infection microbiology

authors： Van Zandt KE,Tuanyok A,Keim PS,Warren RL,Gelhaus HC

更新日期：2012-09-26 00:00:00

abstract：:Lipophilic yeasts of the genus Malassezia are important skin commensals and opportunistic skin pathogens in a variety of animals. The species M. pachydermatis was first isolated from the skin of a captive Indian rhinoceros with an exfoliative dermatitis in 1925, recognized as an important otic pathogen of dogs in the ...

journal_title：Frontiers in cellular and infection microbiology

authors： Guillot J,Bond R

更新日期：2020-02-28 00:00:00

abstract：:Syf1 is a tetratricopeptide repeat (TPR) protein implicated in transcription elongation, spliceosome conformation, mRNA nuclear-cytoplasmic export and transcription-coupled DNA repair. Recently, we identified the spliceosomal components of the human parasite Entamoeba histolytica, among them is EhSyf. Molecular predic...

journal_title：Frontiers in cellular and infection microbiology

authors： Torres-Cifuentes DM,Galindo-Rosales JM,Saucedo-Cárdenas O,Valdés J

更新日期：2018-07-09 00:00:00

abstract：:Shiga toxin (Stx)-producing Escherichia coli (STEC) O157:H7 is an enteric pathogen that causes life-threatening disease in humans, with cattle being major natural reservoirs. A group of STEC O157:H7 with a dramatic combination of high virulence potentials and super-shedder bovine origin have been isolated. Here, an ST...

journal_title：Frontiers in cellular and infection microbiology

authors： Teng L,Lee S,Park D,Jeong KC

更新日期：2020-06-05 00:00:00

abstract：:Given the increasing prevalence of antibiotic resistance among bacterial strains and the side effects caused by synthetic drugs, it is increasingly important to investigate potential herbal alternatives. In the present study, antimicrobial, cell cytotoxicity, and cleaning tests were performed to evaluate the potential...

journal_title：Frontiers in cellular and infection microbiology

authors： Shi Y,Deng Z,Yang Y,Cui L,Chen T,Hu M,Xie L,Yang J

更新日期：2019-05-10 00:00:00

abstract：:Rift Valley fever (RVF) is endemic to sub-Saharan Africa, and has spread into Madagascar, Egypt, Saudi Arabia, and Yemen. Rift Valley fever virus (RVFV) of the family Bunyaviridae, genus Phlebovirus causes hemorrhagic fever, neurological disorders or blindness in humans, and high rate abortion and fetal malformation i...

journal_title：Frontiers in cellular and infection microbiology

authors： Indran SV,Ikegami T

更新日期：2012-10-26 00:00:00

abstract：:Infections with parasites of the genus Leishmania lead to a rapid, but transient activation of natural killer (NK) cells. In mice activation of NK cells requires a toll-like-receptor 9-dependent stimulation of dendritic cells (DC) which is followed by the production of IL-12. Although NK cells appear to be non-essenti...

journal_title：Frontiers in cellular and infection microbiology

authors： Bogdan C

更新日期：2012-05-29 00:00:00

abstract：:Candida species are known to differ in their ability to cause infection and have been shown to display varied susceptibilities to antifungal drugs. Treatment with the echinocandin, caspofungin, leads to compensatory alterations in the fungal cell wall. This study was performed to compare the structure and composition ...

journal_title：Frontiers in cellular and infection microbiology

authors： Walker LA,Munro CA

更新日期：2020-05-12 00:00:00

abstract：:Systemic and endemic mycoses are considered life-threatening respiratory diseases which are caused by a group of dimorphic fungal pathogens belonging to the genera Histoplasma, Coccidioides, Blastomyces, Paracoccidioides, Talaromyces, and the newly described pathogen Emergomyces. T-cell mediated immunity, mainly T hel...

journal_title：Frontiers in cellular and infection microbiology

authors： Puerta-Arias JD,Mejía SP,González Á

更新日期：2020-12-14 00:00:00

abstract：:The worldwide increase in antibiotic-resistant pathogens means that identification of alternative antibacterial drug targets and the subsequent development of new treatment strategies are urgently required. One such new target is the quorum sensing (QS) system. Coral microbial consortia harbor an enormous diversity of...

journal_title：Frontiers in cellular and infection microbiology

authors： Ma ZP,Song Y,Cai ZH,Lin ZJ,Lin GH,Wang Y,Zhou J

更新日期：2018-05-08 00:00:00

abstract：:Objectives: The emergence of carbapenem-resistant Enterobacteriaceae, especially Klebsiella pneumoniae, has become a major concern in clinic settings. Combination therapy is gaining momentum to counter the secondary resistance and potential suboptimal efficacy of monotherapy. The aim of this study was to evaluate the ...

journal_title：Frontiers in cellular and infection microbiology

authors： Yu W,Zhou K,Guo L,Ji J,Niu T,Xiao T,Shen P,Xiao Y

更新日期：2017-06-16 00:00:00

abstract：:Histoplasmosis is one of the most frequent systemic mycosis in HIV patients. In these patients, histoplasmosis has high rates of morbidity/mortality if diagnosis and treatment are delayed. Despite its relevance, there is a paucity of information concerning the interaction between Histoplasma capsulatum and the human h...

journal_title：Frontiers in cellular and infection microbiology

authors： Almeida MA,Almeida-Paes R,Guimarães AJ,Valente RH,Soares CMA,Zancopé-Oliveira RM

更新日期：2020-10-29 00:00:00

abstract：:Sepsis is a life-threatening health condition caused by infectious pathogens of the respiratory tract, and accounts for 28-50% of annual deaths in the US alone. Current treatment regimen advocates the use of corticosteroids as adjunct treatment with antibiotics, for their broad inhibitory effect on the activity and pr...

journal_title：Frontiers in cellular and infection microbiology

authors： Ngo Ndjom CG,Kantor LV,Jones HP

更新日期：2017-06-22 00:00:00

abstract：:Brucella spp. cause undulant fever in humans and brucellosis in variety of other animals. Both innate and adaptive immunity have been shown to be important in controlling Brucella infection. Toll-like receptors (TLRs) represent a group of pattern recognition receptors (PRRs) that play critical roles in the host innate...

journal_title：Frontiers in cellular and infection microbiology

authors： Pei J,Ding X,Fan Y,Rice-Ficht A,Ficht TA

更新日期：2012-09-07 00:00:00

abstract：:Non-optimal vaginal microbiota, as observed in bacterial vaginosis (BV), is typically characterized by a depletion of beneficial lactobacilli and an abundance of numerous anaerobes. These non-optimal conditions are associated with subclinical cervicovaginal inflammation and an increased risk of HIV infection compared ...

journal_title：Frontiers in cellular and infection microbiology

authors： Delgado-Diaz DJ,Tyssen D,Hayward JA,Gugasyan R,Hearps AC,Tachedjian G

更新日期：2020-01-10 00:00:00

abstract：:Hundred-thousands of fungal species are present in our environment, including normal colonizers that constitute part of the human microbiota. The homeostasis of host-fungus interactions encompasses efficient fungal sensing, tolerance at mucosal surfaces, as well as antifungal defenses. Decrease in host immune fitness ...

journal_title：Frontiers in cellular and infection microbiology

authors： Bourgeois C,Kuchler K

更新日期：2012-11-22 00:00:00

abstract：:Staphylococcus aureus is the leading etiologic agent of orthopedic implant infections. Here a ribocluster of 27 S. aureus strains underwent further molecular characterization and subtyping by multilocus sequence typing (MLST) and spa-typing. This cluster had been detected by automated ribotyping (with the EcoRI restri...

journal_title：Frontiers in cellular and infection microbiology

authors： Montanaro L,Ravaioli S,Ruppitsch W,Campoccia D,Pietrocola G,Visai L,Speziale P,Allerberger F,Arciola CR

更新日期：2016-02-16 00:00:00

abstract：:Chronic HCV infection is characterized by several immunological alterations, such as the accumulation of suppressor cells and of hyperactivated T lymphocytes. However, it is unclear whether direct-acting antiviral (DAA)-mediated HCV clearance restores immune dysfunctions. We performed a phenotypic characterization by ...

journal_title：Frontiers in cellular and infection microbiology

authors： Telatin V,Nicoli F,Frasson C,Menegotto N,Barbaro F,Castelli E,Erne E,Palù G,Caputo A

更新日期：2019-06-14 00:00:00

abstract：:Deposition of Burkholderia pseudomallei within either the lungs or nasal passages of the Balb/c murine model resulted in different infection kinetics. The infection resulting from the inhalation of B. pseudomallei within a 12 μm particle aerosol was prolonged compared to a 1 μm particle aerosol with a mean time-to-dea...

journal_title：Frontiers in cellular and infection microbiology

authors： Thomas RJ,Davies C,Nunez A,Hibbs S,Eastaugh L,Harding S,Jordan J,Barnes K,Oyston P,Eley S

更新日期：2012-07-23 00:00:00

abstract：:Response regulators are a critical part of the two-component system of gene expression regulation in bacteria, transferring a signal from a sensor kinase into DNA binding activity resulting in alteration of gene expression. In this study, we investigated a previously uncharacterized response regulator in Francisella n...

journal_title：Frontiers in cellular and infection microbiology

authors： Dean SN,Milton ME,Cavanagh J,van Hoek ML

更新日期：2020-03-13 00:00:00

abstract：:Myocarditis, inflammation of the heart muscle, affects all demographics and is a major cause of sudden and unexpected death in young people. It is most commonly caused by viral infections of the heart, with coxsackievirus B3 (CVB3) being among the most prevalent pathogens. To understand the molecular pathogenesis of C...

journal_title：Frontiers in cellular and infection microbiology

authors： Hanson PJ,Hossain AR,Qiu Y,Zhang HM,Zhao G,Li C,Lin V,Sulaimon S,Vlok M,Fung G,Chen VH,Jan E,McManus BM,Granville DJ,Yang D

更新日期：2019-07-24 00:00:00

abstract：:Human coronaviruses, which can cause a range of infectious diseases, have been studied for nearly 60 years. The field has gained renewed interest from researchers around the world due to the COVID-19 outbreak in late 2019. Despite a large amount of research, little is known about the knowledge structure and developing...

journal_title：Frontiers in cellular and infection microbiology

authors： Deng Z,Chen J,Wang T

更新日期：2020-09-23 00:00:00

abstract：:Enterococcus faecium is a clinically important pathogen associated with opportunistic infection and multi-drug resistance. E. faecium has been shown to produce membrane vesicles (MVs), but MV production by E. faecium under antibiotic stress conditions and the pathogenic traits thereof have yet to be determined. This s...

journal_title：Frontiers in cellular and infection microbiology

authors： Kim MH,Kim SY,Son JH,Kim SI,Lee H,Kim S,Shin M,Lee JC

更新日期：2019-08-14 00:00:00

abstract：:Culture-independent metagenomic methodologies have enabled detection and identification of microorganisms in various biological systems and often revealed complex and unknown microbiomes. In many organisms, the microbiome outnumbers the host cells and greatly affects the host biology and fitness. Ticks are hematophago...

journal_title：Frontiers in cellular and infection microbiology

authors： Guizzo MG,Neupane S,Kucera M,Perner J,Frantová H,da Silva Vaz I,de Oliveira PL,Kopacek P,Zurek L

更新日期：2020-05-08 00:00:00

abstract：:The type VI secretion system (T6SS) secretes numerous toxins for bacteria-bacteria competition. TplE is a newly identified trans-kingdom toxin secreted by the T6SS in Pseudomonas aeruginosa, while TplEi neutralizes the toxic effect of TplE to protect bacteria autointoxication. Blocking the interaction of TplE-TplEi co...

journal_title：Frontiers in cellular and infection microbiology

authors： Gao X,Mu Z,Qin B,Sun Y,Cui S

更新日期：2017-09-20 00:00:00

abstract：:Toxoplasma gondii is a prevalent parasite of mammals and birds including up to 30% of humans world-wide. Primary infection of immunocompetent hosts leads to a robust cell-mediated immune response, which controls but does not clear the infection, thus enabling long-term parasite persistence in brain and muscle tissues....

journal_title：Frontiers in cellular and infection microbiology

authors： Ehmen HG,Lüder CGK

更新日期：2019-06-28 00:00:00

abstract：:Mycoplasma hyopneumoniae (M. hyopneumoniae) is the causative agent of pandemic pneumonia among pigs, namely, swine enzootic pneumonia. Although M. hyopneumoniae was first identified in 1965, little is known regarding its metabolic pathways, which might play a pivotal role during disease pathogenesis. Lipoate is an ess...

journal_title：Frontiers in cellular and infection microbiology

authors： Zhu K,Chen H,Jin J,Wang N,Ma G,Huang J,Feng Y,Xin J,Zhang H,Liu H

更新日期：2020-04-21 00:00:00

abstract：:Salmonella is a facultative intracellular Gram-negative bacterium, responsible for a wide range of food- and water-borne diseases ranging from gastroenteritis to typhoid fever depending on hosts and serotypes. Salmonella thus represents a major threat to public health. A key step in Salmonella pathogenesis is the inva...

journal_title：Frontiers in cellular and infection microbiology

authors： Mambu J,Virlogeux-Payant I,Holbert S,Grépinet O,Velge P,Wiedemann A

更新日期：2017-12-08 00:00:00

abstract：:Shigella is the major cause of bacillary dysentery world-wide. It is divided into four species, named S. flexneri, S. sonnei, S. dysenteriae, and S. boydii, which are distinct genomically and in their ability to cause disease. Shigellosis, the clinical presentation of Shigella infection, is characterized by watery dia...

journal_title：Frontiers in cellular and infection microbiology

authors： Mattock E,Blocker AJ

更新日期：2017-03-24 00:00:00