Caspofungin Induced Cell Wall Changes of Candida Species Influences Macrophage Interactions.

abstract：:Relapsing fever still remains a neglected disease and little is known on its reservoir, tick vector and physiopathology in the vertebrate host. The disease occurs in temperate as well as tropical countries. Relapsing fever borreliae are spirochaetes, members of the Borreliaceae family which also contain Lyme disease s...

journal_title：Frontiers in cellular and infection microbiology

authors： Talagrand-Reboul E,Boyer PH,Bergström S,Vial L,Boulanger N

更新日期：2018-04-04 00:00:00

abstract：:Objectives:Pneumocystis jirovecii pneumonia (PCP) is an AIDS-defining illness. In patients with HIV, the benefit of PCP prophylaxis is well-defined when the CD4 T-cell count decreases below 200 cells/μL. In other immunocompromised patients, the value of PCP prophylaxis is not always as well-established. This study aim...

journal_title：Frontiers in cellular and infection microbiology

authors： Dunbar A,Schauwvlieghe A,Algoe S,van Hellemond JJ,Reynders M,Vandecasteele S,Boelens J,Depuydt P,Rijnders B

更新日期：2020-05-15 00:00:00

abstract：:In 2019, the United States Food and Drug Administration accorded restricted approval to Sanofi Pasteur's Dengvaxia, a live attenuated vaccine (LAV) for dengue fever, a mosquito-borne viral disease, caused by four antigenically distinct dengue virus serotypes (DENV 1-4). The reason for this limited approval is the conc...

journal_title：Frontiers in cellular and infection microbiology

authors： Shukla R,Ramasamy V,Shanmugam RK,Ahuja R,Khanna N

更新日期：2020-10-22 00:00:00

abstract：:Ticks modulate their hosts' defense responses by secreting a biopharmacopiea of hundreds to thousands of proteins and bioactive chemicals into the feeding site (tick-host interface). These molecules and their functions evolved over millions of years as ticks adapted to blood-feeding, tick lineages diverged, and host-s...

journal_title：Frontiers in cellular and infection microbiology

authors： Mans BJ,Featherston J,de Castro MH,Pienaar R

更新日期：2017-09-25 00:00:00

abstract：:We have previously demonstrated that Candida albicans induces differentiation of hematopoietic stem and progenitor cells (HSPCs) toward the myeloid lineage both in vitro and in vivo in a TLR2- and Dectin-1-dependent manner, giving rise to functional macrophages. In this work, we used an ex vivo model to investigate th...

journal_title：Frontiers in cellular and infection microbiology

authors： Martínez A,Bono C,Megías J,Yáñez A,Gozalbo D,Gil ML

更新日期：2018-09-03 00:00:00

abstract：:The oral microbiome can play a role in the instigation and progression of oral diseases that can manifest into other systemic conditions. These associations encourage the exploration of oral dysbiosis leading to the pathogenesis of cancers. In this study, oral rinse was used to characterize the oral microbiome fluctua...

journal_title：Frontiers in cellular and infection microbiology

authors： Lim Y,Fukuma N,Totsika M,Kenny L,Morrison M,Punyadeera C

更新日期：2018-08-03 00:00:00

abstract：:Schistosomes, a class of parasitic trematode worms, cause schistosomiasis. Accumulating evidence suggests that microRNAs (miRNAs)-small, non-coding RNAs that are known to play critical regulatory roles in many organisms-may be involved in schistosome development and sexual maturation, as well as the pathogenesis of sc...

journal_title：Frontiers in cellular and infection microbiology

authors： Zhu L,Liu J,Cheng G

更新日期：2014-11-11 00:00:00

abstract：:The Asian tiger mosquito Aedes (Stegomya) albopictus is an invasive species that has spread across the world in the last two decades, showing a great capacity to adapt to contrasting climates and environments. While demonstrated in many insects, the contribution of bacterial symbionts in Aedes ecology is a challenging...

journal_title：Frontiers in cellular and infection microbiology

authors： Minard G,Tran FH,Dubost A,Tran-Van V,Mavingui P,Moro CV

更新日期：2014-05-14 00:00:00

abstract：:Objectives: To evaluate metagenomic next-generation sequencing (mNGS) as a diagnostic tool in detecting pathogens from osteoarticular infection (OAI) samples. Methods: 130 samples of joint fluid, sonicate fluid, and tissue were prospectively collected from 92 patients with OAI. The performance of mNGS and microbiology...

journal_title：Frontiers in cellular and infection microbiology

authors： Huang ZD,Zhang ZJ,Yang B,Li WB,Zhang CJ,Fang XY,Zhang CF,Zhang WM,Lin JH

更新日期：2020-09-17 00:00:00

abstract：:Previous studies demonstrated that oral antibiotic (ABX) treatment prior to and during influenza A virus (IAV) infection of adult mice profoundly altered gut microbiota (GM) and was associated with increased susceptibility and impaired immunity to IAV. We examined the impact of ABX during critical times relevant to th...

journal_title：Frontiers in cellular and infection microbiology

authors： Fuglsang E,Pizzolla A,Krych L,Nielsen DS,Brooks AG,Frøkiær H,Reading PC

更新日期：2018-09-12 00:00:00

abstract：:Melioidosis is a neglected tropical disease with high mortality rate. It is caused by the Gram-negative, CDC category B select agent Burkholderia pseudomallei (B. ps) that is intrinsically resistant to first-line antibiotics. An antibody-based vaccine is likely to be the most effective control measure. Previous studie...

journal_title：Frontiers in cellular and infection microbiology

authors： Chaichana P,Kronsteiner B,Rongkard P,Teparrukkul P,Limmathurotsakul D,Chantratita N,Day NPJ,Fletcher HA,Dunachie SJ

更新日期：2020-08-26 00:00:00

abstract：:Iron is an absolute requirement for both the host and most pathogens alike and is needed for normal cellular growth. The acquisition of iron by biological systems is regulated to circumvent toxicity of iron overload, as well as the growth deficits imposed by iron deficiency. In addition, hosts, such as humans, need to...

journal_title：Frontiers in cellular and infection microbiology

authors： Fourie R,Kuloyo OO,Mochochoko BM,Albertyn J,Pohl CH

更新日期：2018-06-05 00:00:00

abstract：:The emerging relapsing fever spirochete Borrelia (B.) miyamotoi is transmitted by ixodid ticks and causes the so-called hard tick-borne relapsing fever or B. miyamotoi disease (BMD). More recently, we identified a surface-exposed molecule, CbiA exhibiting complement binding and inhibitory capacity and rendering spiroc...

journal_title：Frontiers in cellular and infection microbiology

authors： Nguyen NTT,Röttgerding F,Devraj G,Lin YP,Koenigs A,Kraiczy P

更新日期：2018-02-02 00:00:00

abstract：Background:Disseminated histoplasmosis remains a major killer of immunocompromised patients in Latin America. Cytological and histological methods are usually present in most hospitals and may represent a precious diagnostic method. We report 15 years of experience of the department of pathology of the Centre Hospitali...

journal_title：Frontiers in cellular and infection microbiology

authors： Drak Alsibai K,Couppié P,Blanchet D,Adenis A,Epelboin L,Blaizot R,Louvel D,Djossou F,Demar M,Nacher M

更新日期：2020-10-29 00:00:00

abstract：:Colorectal adenocarcinoma (CRC) is a common tumor with high mortality rates. Interestingly, CRC was found to be colonized by the oral anaerobic bacteria Fusobacterium nucleatum, which accelerates tumor progression and enables immune evasion. The CRC-specific colonization by fusobacteria is mediated through the recogni...

journal_title：Frontiers in cellular and infection microbiology

authors： Abed J,Maalouf N,Parhi L,Chaushu S,Mandelboim O,Bachrach G

更新日期：2017-06-30 00:00:00

abstract：:Protein secretion systems are vital for prokaryotic life, as they enable bacteria to acquire nutrients, communicate with other species, defend against biological and chemical agents, and facilitate disease through the delivery of virulence factors. In this review, we will focus on the recently discovered type IX secre...

journal_title：Frontiers in cellular and infection microbiology

authors： Lasica AM,Ksiazek M,Madej M,Potempa J

更新日期：2017-05-26 00:00:00

abstract：:Background:Staphylococcus aureus biofilms contribute negatively to a number of chronic conditions, including chronic rhinosinusitis (CRS). With the inherent tolerance of biofilm-bound bacteria to antibiotics and the global problem of bacterial antibiotic resistance, the need to develop novel therapeutics is paramount....

journal_title：Frontiers in cellular and infection microbiology

authors： Drilling AJ,Ooi ML,Miljkovic D,James C,Speck P,Vreugde S,Clark J,Wormald PJ

更新日期：2017-02-24 00:00:00

abstract：:Infections with parasites of the genus Leishmania lead to a rapid, but transient activation of natural killer (NK) cells. In mice activation of NK cells requires a toll-like-receptor 9-dependent stimulation of dendritic cells (DC) which is followed by the production of IL-12. Although NK cells appear to be non-essenti...

journal_title：Frontiers in cellular and infection microbiology

authors： Bogdan C

更新日期：2012-05-29 00:00:00

abstract：:Proton pump inhibitors (PPIs) are the standard therapy for gastroesophageal reflux disease. In adults, PPI treatment is associated with Clostridium difficile infections (CDI). In contrast to adults the microbiome of infants develops from sterility at birth toward an adult-like profile in the first years of life. The e...

journal_title：Frontiers in cellular and infection microbiology

authors： Castellani C,Singer G,Kashofer K,Huber-Zeyringer A,Flucher C,Kaiser M,Till H

更新日期：2017-10-11 00:00:00

abstract：:The concept of pathogenesis has evolved considerably over recent years, and the scenario "a microbe + virulence factors = disease" is probably far from reality in a number of cases. Actual pathogens have extremely broad biological diversity and are found in all major groups of microorganisms (viruses, bacteria, fungi,...

journal_title：Frontiers in cellular and infection microbiology

authors： Vayssier-Taussat M,Albina E,Citti C,Cosson JF,Jacques MA,Lebrun MH,Le Loir Y,Ogliastro M,Petit MA,Roumagnac P,Candresse T

更新日期：2014-03-05 00:00:00

abstract：:Rift Valley fever (RVF) is endemic to sub-Saharan Africa, and has spread into Madagascar, Egypt, Saudi Arabia, and Yemen. Rift Valley fever virus (RVFV) of the family Bunyaviridae, genus Phlebovirus causes hemorrhagic fever, neurological disorders or blindness in humans, and high rate abortion and fetal malformation i...

journal_title：Frontiers in cellular and infection microbiology

authors： Indran SV,Ikegami T

更新日期：2012-10-26 00:00:00

abstract：:The endosymbiotic origin of eukaryotes brought together two disparate genomes in the cell. Additionally, eukaryotic natural history has included other endosymbiotic events, phagotrophic consumption of organisms, and intimate interactions with viruses and endoparasites. These phenomena facilitated large-scale lateral g...

journal_title：Frontiers in cellular and infection microbiology

authors： Aravind L,Anantharaman V,Zhang D,de Souza RF,Iyer LM

更新日期：2012-06-29 00:00:00

abstract：:Deposition of Burkholderia pseudomallei within either the lungs or nasal passages of the Balb/c murine model resulted in different infection kinetics. The infection resulting from the inhalation of B. pseudomallei within a 12 μm particle aerosol was prolonged compared to a 1 μm particle aerosol with a mean time-to-dea...

journal_title：Frontiers in cellular and infection microbiology

authors： Thomas RJ,Davies C,Nunez A,Hibbs S,Eastaugh L,Harding S,Jordan J,Barnes K,Oyston P,Eley S

更新日期：2012-07-23 00:00:00

abstract：:The major Mycobacterium tuberculosis virulence factor ESAT-6 exported by the ESX-1 secretion system has been described as a pro-apoptotic factor by several independent groups in recent years, sustaining a role for apoptosis in M. tuberculosis pathogenesis. This role has been supported by independent studies in which a...

journal_title：Frontiers in cellular and infection microbiology

authors： Aguiló N,Marinova D,Martín C,Pardo J

更新日期：2013-12-04 00:00:00

abstract：:Ocular toxoplasmosis is one of the most common complications caused by the infection with the parasite Toxoplasma gondii. The risk of developing eye lesions and impaired vision is considered higher in Brazil than other countries. The clinical diagnosis is difficult and the use of sensitive and specific laboratorial me...

journal_title：Frontiers in cellular and infection microbiology

authors： Murata FHA,Previato M,Frederico FB,Barbosa AP,Nakashima F,de Faria GM Jr,Silveira Carvalho AP,Meira Strejevitch CDS,Pereira-Chioccola VL,Castiglioni L,de Mattos LC,Siqueira RC,Brandão de Mattos CC

更新日期：2020-02-07 00:00:00

abstract：:Antifolate resistance is significant in Kenya and presumed to result from extensive use and cross-resistance between antifolate antimalarials and antibiotics, including cotrimoxazole/Bactrim used for HIV-1 chemotherapy. However, little is known about antifolate-resistant malaria in the context of newly diagnosed HIV-1...

journal_title：Frontiers in cellular and infection microbiology

authors： Torrevillas BK,Garrison SM,McKeeken AJ,Patel D,Van Leuven JT,Dizon NI,Rivas KI,Hathaway NJ,Bailey JA,Waitumbi JN,Kifude CM,Oyieko J,Stewart VA,Luckhart S

更新日期：2020-11-26 00:00:00

abstract：:Metagenomic approaches applied to viruses have highlighted their prevalence in almost all microbial ecosystems investigated. In all ecosystems, notably those associated with humans or animals, the viral fraction is dominated by bacteriophages. Whether they contribute to dysbiosis, i.e., the departure from microbiota c...

journal_title：Frontiers in cellular and infection microbiology

authors： De Paepe M,Leclerc M,Tinsley CR,Petit MA

更新日期：2014-03-28 00:00:00

abstract：:A cohort study was conducted to evaluate oral microbial diversity among toddlers aged 12-24 months, and to describe the dynamic processes of colonization, development, and stabilization of the oral microflora during tooth eruption using high-throughput sequencing technology. A total of 20 healthy toddlers aged 12 mont...

journal_title：Frontiers in cellular and infection microbiology

authors： Li F,Tao D,Feng X,Wong MCM,Lu H

更新日期：2018-12-04 00:00:00

abstract：:Vaccination has had a major impact on the control of infectious diseases. However, there are still many infectious diseases for which the development of an effective vaccine has been elusive. In many cases the failure to devise vaccines is a consequence of the inability of vaccine candidates to evoke appropriate immun...

journal_title：Frontiers in cellular and infection microbiology

authors： Gregory AE,Titball R,Williamson D

更新日期：2013-03-25 00:00:00

abstract：:Toxoplasma gondii is a prevalent parasite of mammals and birds including up to 30% of humans world-wide. Primary infection of immunocompetent hosts leads to a robust cell-mediated immune response, which controls but does not clear the infection, thus enabling long-term parasite persistence in brain and muscle tissues....

journal_title：Frontiers in cellular and infection microbiology

authors： Ehmen HG,Lüder CGK

更新日期：2019-06-28 00:00:00