Autonomic function in amnestic and non-amnestic mild cognitive impairment: spectral heart rate variability analysis provides evidence for a brain-heart axis.

abstract：:Cancer-specific promoter driven replication of oncolytic adenovirus (Ad) is cancer-specific, but shows low transcriptional activity. Thus, we generated several chimeric α-fetoprotein (AFP) promoter variants, containing reconstituted enhancer and silencer regions, to preferentially drive Ad replication in hepatocellula...

journal_title：Scientific reports

authors： Yoon AR,Hong J,Kim M,Yun CO

更新日期：2018-02-02 00:00:00

abstract：:Hyperspectral imaging technique was employed to determine spatial distributions of chlorophyll (Chl), and carotenoid (Car) contents in cucumber leaves in response to angular leaf spot (ALS). Altogether, 196 hyperspectral images of cucumber leaves with five infection severities of ALS were captured by a hyperspectral i...

journal_title：Scientific reports

authors： Zhao YR,Li X,Yu KQ,Cheng F,He Y

更新日期：2016-06-10 00:00:00

abstract：:Mechanical interlocking is widely applied in industry and general lives of human beings. In this work, we realized the control of locking or sliding states of cotton fibers on the metal surfaces with slightly different textures through traditional machining. Three types of sliding states, i.e., locking, one-way slidin...

journal_title：Scientific reports

authors： Zhang Y,Tian Y,Meng Y

更新日期：2016-05-09 00:00:00

abstract：:Patterns of temperature fluctuations in nature affect numerous biological processes, yet, empirical studies often utilize constant temperature treatments. This can limit our understanding of how thermally sensitive species respond to ecologically relevant temperatures. Research on turtles with temperature-dependent se...

journal_title：Scientific reports

authors： Carter AW,Sadd BM,Tuberville TD,Paitz RT,Bowden RM

更新日期：2018-01-08 00:00:00

abstract：:Staphylococcus aureus infection is a rising public health care threat. S. aureus is believed to have elaborate regulatory networks that orchestrate its virulence. Despite its importance, the systematic understanding of the transcriptional landscape of S. aureus is limited. Here, we describe the primary transcriptome l...

journal_title：Scientific reports

authors： Choe D,Szubin R,Dahesh S,Cho S,Nizet V,Palsson B,Cho BK

更新日期：2018-02-02 00:00:00

abstract：:Glomerular filtration rate (GFR) and urinary albumin excretion rate (UAER) are used to diagnose and classify the severity of chronic kidney disease. Total adiponectin (T-AN) and high molecular weight adiponectin (H-AN) assays were developed using the fully automated immunoassay system, HI-1000 and their significance o...

journal_title：Scientific reports

authors： Watanabe T,Fujimoto Y,Morimoto A,Nishiyama M,Kawai A,Okada S,Aiba M,Kawano T,Kawahigashi M,Ishizu M,Mori H,Matsuhisa M,Hata A,Funaki M,Hashida S

更新日期：2020-09-28 00:00:00

abstract：:We present a new method for the design of devices to manipulate the displacement field in Elastic materials. It consists of solving a nonlinear optimization problem where the objective function defines the error in matching a desired displacement field, and the design variables determine the required material distribu...

journal_title：Scientific reports

authors： Fachinotti VD,Peralta I,Albanesi AE

更新日期：2018-06-29 00:00:00

abstract：:Calciprotein particles (CPP) are solid-phase calcium-phosphate bound to serum protein fetuin-A and dispersed as colloids in the blood. Recent clinical studies indicated that serum CPP levels were increased with decline of renal function and associated with inflammation and vascular calcification. However, CPP assays u...

journal_title：Scientific reports

authors： Miura Y,Iwazu Y,Shiizaki K,Akimoto T,Kotani K,Kurabayashi M,Kurosu H,Kuro-O M

更新日期：2018-01-19 00:00:00

abstract：:Protein aggregation is a common biological phenomenon, observed in different physiological and pathological conditions. Decreased protein solubility and a tendency to aggregate is also observed during physiological aging but the causes are currently unknown. Herein we performed a biophysical separation of aging-relate...

journal_title：Scientific reports

authors： Tanase M,Urbanska AM,Zolla V,Clement CC,Huang L,Morozova K,Follo C,Goldberg M,Roda B,Reschiglian P,Santambrogio L

更新日期：2016-01-18 00:00:00

abstract：:The intermolt crustacean Y-organ (YO) maintains a basal state mediated by pulsatile release of molt inhibiting hormone (MIH), a neuropeptide produced in the eyestalk ganglia, inhibiting YO ecdysteroidogenesis. Reduction of MIH results in YO activation and the animal enters premolt. In the crab, Gecarcinus lateralis, m...

journal_title：Scientific reports

authors： Shyamal S,Das S,Guruacharya A,Mykles DL,Durica DS

更新日期：2018-05-09 00:00:00

abstract：:Both CC and CXC-class chemokines drive inflammatory disease. Tick salivary chemokine-binding proteins (CKBPs), or evasins, specifically bind subsets of CC- or CXC-chemokines, and could precisely target disease-relevant chemokines. Here we have used yeast surface display to identify two tick evasins: a CC-CKBP, P1243 f...

journal_title：Scientific reports

authors： Alenazi Y,Singh K,Davies G,Eaton JRO,Elders P,Kawamura A,Bhattacharya S

更新日期：2018-04-20 00:00:00

abstract：:Various MRI techniques, including myelin water imaging, T1w/T2w ratio mapping and diffusion-based imaging can be used to characterize tissue microstructure. However, surprisingly few studies have examined the degree to which these MRI measures are related within and between various brain regions. Therefore, whole-brai...

journal_title：Scientific reports

authors： Uddin MN,Figley TD,Solar KG,Shatil AS,Figley CR

更新日期：2019-02-21 00:00:00

abstract：:Atherosclerotic arteries exhibit characteristic constrictions and substantial deviations from cylindrical shape. Therefore, determining the artery's cross-section along the centerline is challenging, although high-resolution isotropic three-dimensional data are available. Herein, we apply high-resolution computed tomo...

journal_title：Scientific reports

authors： Buscema M,Hieber SE,Schulz G,Deyhle H,Hipp A,Beckmann F,Lobrinus JA,Saxer T,Müller B

更新日期：2019-10-04 00:00:00

abstract：:When making choices between smaller, sooner rewards and larger, later ones, people tend to discount future outcomes. Individual differences in temporal discounting in older adults have been associated with episodic memory abilities and entorhinal cortical thickness. The cause of this association between better memory ...

journal_title：Scientific reports

authors： Lempert KM,MacNear KA,Wolk DA,Kable JW

更新日期：2020-04-14 00:00:00

abstract：:The development of electrochemical biosensors for the simultaneous detection of ascorbic acid (AA), dopamine (DA), uric acid (UA), tryptophan (Trp), and nitrite ([Formula: see text]) in human serum is reported in this work. Free-standing graphene nanosheets were fabricated on Ta wire using the chemical vapor depositio...

journal_title：Scientific reports

authors： Wang X,Gao D,Li M,Li H,Li C,Wu X,Yang B

更新日期：2017-08-01 00:00:00

abstract：:Many insects possess the ability to detect fine fluctuations in the environmental CO2 concentration. In herbivorous species, plant-emitted CO2, in combination with other sensory cues, affect many behaviors including foraging and oviposition. In contrast to the comprehensive knowledge obtained on the insect olfactory p...

journal_title：Scientific reports

authors： Chu X,Kc P,Ian E,Kvello P,Liu Y,Wang GR,Berg BG

更新日期：2020-11-16 00:00:00

abstract：:To evaluate the association between vision-related quality of life (QoL), physical inactivity, and locomotor dysfunction in subjects with visual impairment.This cross-sectional study included 215 visually impaired subjects recruited from six ophthalmology departments in Japan. The physical inactivity and locomotor dys...

journal_title：Scientific reports

authors： Inoue S,Kawashima M,Hiratsuka Y,Nakano T,Tamura H,Ono K,Murakami A,Tsubota K,Yamada M

更新日期：2018-08-13 00:00:00

abstract：:Brain-computer interface (BCI) systems having the ability to classify brain waves with greater accuracy are highly desirable. To this end, a number of techniques have been proposed aiming to be able to classify brain waves with high accuracy. However, the ability to classify brain waves and its implementation in real-...

journal_title：Scientific reports

authors： Kumar S,Sharma A,Tsunoda T

更新日期：2019-06-24 00:00:00

abstract：:There is a demand for ultra low-loss metal films with high-quality single crystals and perfect surface for nanophotonics and quantum information processing. Many researches are devoted to alternative materials, but silver is by far theoretically the most preferred low-loss material at optical and near-IR frequencies. ...

journal_title：Scientific reports

authors： Rodionov IA,Baburin AS,Gabidullin AR,Maklakov SS,Peters S,Ryzhikov IA,Andriyash AV

更新日期：2019-08-22 00:00:00

abstract：:The charge transport properties of hybrid halide perovskites are investigated with a combination of density functional theory including van der Waals interaction and the Boltzmann theory for diffusive transport in the relaxation time approximation. We find the mobility of electrons to be in the range 5-10 cm(2)V(-1)s(...

journal_title：Scientific reports

authors： Motta C,El-Mellouhi F,Sanvito S

更新日期：2015-08-03 00:00:00

abstract：:A new, extraordinary palaeontinid Hallakkungis amisanus Nam, Wang &Szwedo, gen. et sp. nov., from the Upper Triassic of the Amisan Formation in Boryeong City, Korea is described. It is the first Palaeontinidae from Korea. The newly described taxon displays a mosaic of characters present in presumed ancestors of this i...

journal_title：Scientific reports

authors： Nam KS,Wang Y,Ren D,Kim JH,Szwedo J

更新日期：2017-01-18 00:00:00

abstract：:Despite our increasing understanding of zebrafish heart development and regeneration, there is limited information about the distribution of endothelial cells (ECs) in the adult zebrafish heart. Here, we investigate and compare the distribution of cardiac ECs (cECs) in adult mouse and zebrafish ventricles. Surprisingl...

journal_title：Scientific reports

authors： Patra C,Kontarakis Z,Kaur H,Rayrikar A,Mukherjee D,Stainier DYR

更新日期：2017-06-02 00:00:00

abstract：:As a class, 'BET' inhibitors disrupt binding of bromodomain and extra-terminal motif (BET) proteins, BRD2, BRD3, BRD4 and BRDT, to acetylated histones preventing recruitment of RNA polymerase 2 to enhancers and promoters, especially super-enhancers, to inhibit gene transcription. As such, BET inhibitors may be useful ...

journal_title：Scientific reports

authors： Gibbons HR,Mi DJ,Farley VM,Esmond T,Kaood MB,Aune TM

更新日期：2019-07-16 00:00:00

abstract：:Because of ubiquity of thioesters, thioesterases play a critical role in metabolism, membrane biosynthesis, signal transduction, and gene regulation. In many bacteria, YbgC is such an enzyme, whose coding gene mostly resides in the tol-pal cluster. Although all other proteins encoded in the tol-pal cluster are clearly...

journal_title：Scientific reports

authors： Gao T,Meng Q,Gao H

更新日期：2017-06-21 00:00:00

abstract：:Copper is an essential trace metal that has been implicated in angiogenesis, the formation of new blood vessels. As tumor growth relies on establishing a functional capillary network for blood supply, copper chelation therapy may hold promise as an anti-cancer strategy by suppressing angiogenesis. To test the anti-ang...

journal_title：Scientific reports

authors： Heuberger DM,Harankhedkar S,Morgan T,Wolint P,Calcagni M,Lai B,Fahrni CJ,Buschmann J

更新日期：2019-10-01 00:00:00

abstract：:Organic matter production and decomposition primarily modulate the atmospheric O2 and CO2 levels. The long term marine primary productivity is controlled by the terrestrial input of phosphorus (P), while the marine P cycle would also affect organic matter production. In the past 540 million years, the evolution of ter...

journal_title：Scientific reports

authors： Wang R,Lang X,Ding W,Liu Y,Huang T,Tang W,Shen B

更新日期：2020-04-02 00:00:00

abstract：:Methods and mechanisms for improvement of photocatalytic activity, are important and popular research topics for renewable energy production and waste water treatment. Here, we demonstrate a facile laser drilling method for engineering well-aligned pore arrays on magnetron-sputtered WS2 nanofilms with increased active...

journal_title：Scientific reports

authors： Ma S,Zeng L,Tao L,Tang CY,Yuan H,Long H,Cheng PK,Chai Y,Chen C,Fung KH,Zhang X,Lau SP,Tsang YH

更新日期：2017-06-09 00:00:00

abstract：:The indiscriminate use of antibiotics has led to the emergence of drug-resistant bacteria which has become one of the biggest challenges of the twenty-first century for the researchers to combat and in turn search for novel targets which could lead to the development of effective and sustainable therapies. Inhibition ...

journal_title：Scientific reports

authors： Prateeksha,Barik SK,Singh BN

更新日期：2019-04-24 00:00:00

abstract：:Plant essential oils are considered as important bio-sources for the development of natural and environmentally safe pest control tools due to their multiple modes of action on insects. In this paper we have evaluated the activity of commercially available thyme oil and its constituents thymol, carvacrol, and p-cymene...

journal_title：Scientific reports

authors： López S,Domínguez A,Guerrero Á,Quero C

更新日期：2021-01-13 00:00:00

abstract：:β-lactam antibiotics act as suicide substrates of transpeptidases responsible for the last cross-linking step of peptidoglycan synthesis in the bacterial cell wall. Nucleophilic attack of the β-lactam carbonyl by the catalytic residue (Ser or Cys) of transpeptidases results in the opening of the β-lactam ring and in t...

journal_title：Scientific reports

authors： Edoo Z,Arthur M,Hugonnet JE

更新日期：2017-08-22 00:00:00