Abstract:
:Multiple myeloma is an incurable malignancy of plasma cells. We retrospectively reviewed the survival outcomes of patients with multiple myeloma in Western Australia (WA) public hospitals over a 10-year period. We did not detect a difference in survival between patients residing the metropolitan Perth and regional areas, despite a paucity of haematology services in regional WA due to low population density in a large geographic area. Patients with R-ISS Stage 3 had the poorest survival in our cohort with median survival of 24 months.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
Ng TF,Burrow S,Leahy M,Augustson B,Trentino K,De Kraa R,Wright M,Carnley Bdoi
10.1111/imj.14905subject
Has Abstractpub_date
2020-07-01 00:00:00pages
869-872issue
7eissn
1444-0903issn
1445-5994journal_volume
50pub_type
杂志文章abstract:BACKGROUND:Advanced training in gastroenterology currently consists of 2 years of core training and 1 elective (non-core) year. We surveyed gastroenterologists 2-7 years following completion of training to determine the strengths and weaknesses of their training. METHODS:All gastroenterologists were invited to partici...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2012.02757.x
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:There is a high risk of developing venous thromboembolism (VTE) following total knee arthroplasty (TKA). Conventional thromboprophylactic agents have limitations, such as route of administration, the need for monitoring, narrow therapeutic windows and interactions. Apixaban is a new oral anticoagulant with t...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13139
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:The thiopurines azathioprine and 6-mercaptopurine are recommended for maintenance of remission in inflammatory bowel disease (IBD). Measurement of concentrations of the metabolites 6-thioguanine nucleotide and 6-methylmercaptopurine helps delineate interindividual variation in metabolism that may underlie va...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1445-5994.2012.02936.x
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Stroke neurologists, vascular surgeons, interventional neuroradiologists and interventional cardiologists have embraced carotid angioplasty and stenting (CAS) because of potential advantages over carotid endarterectomy (CEA). At Austin Health, a multidisciplinary neuro-interventional group was formed to stan...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02285.x
更新日期:2011-11-01 00:00:00
abstract::Influenza vaccination is an important preventative health measure. A significant proportion of general medical inpatients meets indications for annual inactivated influenza vaccination (IIV), as recommended by the Australian National Immunisation Programme. This study explores opportunities to provide IIV to eligible ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14275
更新日期:2019-05-01 00:00:00
abstract::Many publications have highlighted a lack of practical competencies in recently qualified interns. Consultation between the University of Queensland and the Medical Education Unit at Redcliffe Hospital identified key areas where intervention could lead to greater work readiness, and the development of a complementary ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02272.x
更新日期:2010-10-01 00:00:00
abstract::It is generally accepted that the prevalence of food allergy has been increasing in recent decades, particularly in westernised countries, yet high-quality evidence that is based on challenge confirmed diagnosis of food allergy to support this assumption is lacking because of the high cost and potential risks associat...
journal_title:Internal medicine journal
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doi:10.1111/imj.13362
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Both low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) have been shown to be equivalent in efficacy and safety profiles for the management of pulmonary embolism (PE). AIMS:To assess the real world management of anticoagulation in PE in a tertiary hospital setting. METHODS:An audit of pat...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12376
更新日期:2014-04-01 00:00:00
abstract::The purpose of this case-control study is to estimate the risks of Stevens-Johnson syndrome or toxic epidermal necrolysis associated with the use of specific drugs. The suspected cases were identified from the computerized hospital discharge file. We calculated crude relative risks and adjusted them for confounding by...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2005.00790.x
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:A number of haematological malignancies can be cured by allogeneic stem cell transplantation but only approximately 30% of Australians have a suitable histocompatible related donor. Matched donors can be found on international registries of unrelated volunteers for a proportion of the remaining patients. For...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2006.01079.x
更新日期:2006-06-01 00:00:00
abstract::This study aimed to identify the incidence of perioperative acute upper gastrointestinal bleeding (UGIB) in our hip fracture patients; to evaluate the characteristics, management and clinical outcomes of these patients; and to explore risk factors and protective factors. Of the 1691 consecutive patients admitted for s...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13809
更新日期:2018-06-01 00:00:00
abstract::Decompressive hemicraniectomy (DHC) has been shown to reduce mortality in malignant middle cerebral artery (MCA) infarction. Our primary objective was to compare 1-year mortality between patients receiving DHC for malignant MCA infarction at our institution based on hospital of origin. We retrospectively reviewed the ...
journal_title:Internal medicine journal
pub_type: 杂志文章,meta分析
doi:10.1111/imj.14050
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Poor lung function is a predictor of future all-cause mortality. In Australia, respiratory diseases are particularly prevalent among the indigenous population, especially in remote communities. However, there are little published pulmonary function tests' (PFT) data of remote-based adult indigenous patients....
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14112
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Type 2 diabetes (T2D) in young adults is associated with a high risk of diabetes complications. AIMS:To investigated the demography and the emergence of complications of young adults with T2D in the central Auckland region where there has been substantial immigration. METHODS:In total, 310 young adults wit...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13623
更新日期:2018-01-01 00:00:00
abstract::To share our experience of establishing an acute outreach service to nursing homes and to evaluate the impact of such service on emergency department presentations, data were drawn from a pre-existing database from 2013 to 2017. Of the 986 acute patients treated in 12 nursing homes over a 23-month period, the acute ge...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究
doi:10.1111/imj.14104
更新日期:2018-11-01 00:00:00
abstract::Haemophagocytic lymphohistiocytosis (HLH) is rare disorder characterised by immune activation leading to cytokine storm and end-organ failure. It is associated with poor prognosis. HLH is predominantly a disease of early childhood, where it often results from genetic defects that impair cytotoxic function of natural k...
journal_title:Internal medicine journal
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doi:10.1111/imj.14891
更新日期:2020-05-10 00:00:00
abstract:BACKGROUND:Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) is a subgroup of oncogene addicted lung cancer that predicts response to tyrosine kinase inhibitors (TKI). However, there is variability in response and survival outcomes in patients with EGFR mutation treated with TKI. AIM:T...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13555
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND AND AIM:To identify the underlying heart disease and microbiological pathogen associated with infective endocarditis (IE) in Chinese patients in one university hospital over a 10-year period. METHODS:We recruited 115 adult patients admitted to Peking University First Hospital from 2002 to 2011 who were diag...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12248
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Iatrogenic medication errors are a cause of medical morbidity and mortality. They result in significant cost to the Australian healthcare system each year. There is limited Australian evidence describing the iatrogenic errors occurring within the hospital system. AIMS:To examine and describe iatrogenic medi...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14940
更新日期:2020-06-15 00:00:00
abstract::Prior randomised studies of immunoglobulin replacement therapy have studied mixed populations with or without a history of infections. Immunoglobulin therapy is expensive and in limited supply suggesting that optimising patient selection is of value. In this retrospective study, infection history identified high-risk ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13205
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Stroke is an Australian health priority area causing considerable levels of disability. We report 90-day outcomes for a cohort of acute stroke patients in New South Wales (NSW), Australia prior to randomization to a large cluster randomized controlled trial (CRCT), the Quality in Acute Stroke Care (QASC) tri...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02330.x
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:There is no mechanism in place for monitoring or quality improvement of cancer multidisciplinary meetings (MDM) in Australia. AIM:To develop a peer-review process for quality improvement of MDM. METHODS:This project involved three phases: (i) development of a draft peer-review framework, supporting documen...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
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更新日期:2017-05-01 00:00:00
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journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1444-0903.2005.00976.x
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:IgE-mediated allergy to the wheat protein omega-5-gliadin (O5G) is associated with wheat-dependent exercise-induced anaphylaxis (WDEIA), where exercise acts as a cofactor, triggering anaphylaxis after wheat ingestion. The wider application of O5G-specific IgE (sIgE) testing has revealed that the manifestatio...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13091
更新日期:2016-06-01 00:00:00
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journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14142
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Despite the frequency of cannula-associated Staphylococcus aureus bacteraemia (CASAB) there is uncertainty regarding the duration of treatment required. AIM:To determine the relationship between the duration and type of treatment for CASAB and subsequent relapse with deep-seated S. aureus infection. METHOD...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2005.00823.x
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Acute poisoning accounts for a significant proportion of the total burden of disease worldwide. While the rate of poisoning fatalities in New Zealand is comparable to other industrialised countries, demographic trends in incidence, particularly including socio-economic indicators and substances involved, are...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12364
更新日期:2014-03-01 00:00:00
abstract::The use of tissue-type plasminogen activator (t-PA) in ischaemic stroke outside of experienced stroke centres remains controversial. The aim of this study was to present the initial experience with t-PA in patients with ischaemic stroke at an institution with no prior experience in i.v. stroke thrombolysis and to comp...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2006.01127.x
更新日期:2006-08-01 00:00:00
abstract::The Australian National Chronic Obstructive Pulmonary Disease (COPD) guidelines recommend that inhaled corticosteroids (ICS) be reserved for patients with a post-bronchodilator forced expiratory volume in 1 s (FEV1 ) less than 50% predicted and those who experience ≥2 exacerbations in 12 months. In total, 707 COPD pat...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13611
更新日期:2017-11-01 00:00:00
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journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13556
更新日期:2017-12-01 00:00:00