Abstract：
OBJECTIVES:To assess and compare the pharmacological effect of different drugs on pain relief after periodontal surgery. MATERIALS AND METHODS:Five databases were searched up to September 2019. The eligible studies comprised randomized clinical trials, involving only adult individuals that received any periodontal surgery and presenting two distinct groups of therapeutic regimens to control postoperative pain. Placebo groups could be included. The risk of bias was assessed with the RoB 2 Cochrane tool and the GRADE system. Meta-analyses were performed using different follow-up and drug comparisons. RESULTS:Overall, 2398 studies were identified, of which 35 were included. Low risk of bias was determined for the majority of the studies. The meta-analyses showed that the comparison of dexamethasone or non-steroidal anti-inflammatory drugs (NSAID) versus placebo favored the use of both interventions in a follow-up of 1 to 8 h for open flap procedures (OFP). However, no statistical difference was found for the comparison between NSAID and dexamethasone for OFP. CONCLUSIONS:Patients may benefit from several pharmacological schemes for pain relief after periodontal surgeries. However, due to the high heterogeneity among studies, no fixed pharmacological protocol could be proposed. CLINICAL RELEVANCE:There is not enough evidence to recommend one therapeutic scheme. However, untreated pain is harmful to the patients and it is not advisable.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Caporossi LS,Dos Santos CS,Calcia TBB,Cenci MS,Muniz FWMG,da Silveira Lima Gdoi
10.1007/s00784-020-03401-6subject
Has Abstractpub_date
2020-08-01 00:00:00pages
2559-2578issue
8eissn
1432-6981issn
1436-3771pii
10.1007/s00784-020-03401-6journal_volume
24pub_type
杂志文章,meta分析abstract：:This study aims to evaluate the inclinations of right and left sides the mandibular fossa in Asian population using computed tomography (CT) images and determine its effects according to the parameters of gender, age, and asymmetry. CT images of the heads of 198 Asian subjects [95 females aged 44.2 ± 20.7 years, range...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-011-0518-y
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVES:This study aimed to conduct a methodological assessment of paper-based systematic reviews (SR) published in oral health using a validated checklist. A secondary objective was to explore temporal trends on methodological quality. MATERIAL AND METHODS:Two electronic databases (OVID Medline and OVID EMBASE) we...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s00784-015-1663-5
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVES:To evaluate, longitudinally, the impacts of orthognathic surgery in patients with skeletal class II malocclusion on oral health-related quality of life (OHRQoL), temporomandibular disorders (TMD) and psychological symptoms. MATERIALS AND METHODS:Forty-three patients with skeletal class II malocclusion who w...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03709-3
更新日期：2021-01-07 00:00:00
abstract：:The aim of the present study was to evaluate the efficacy of autogenous bone graft (ABG) with and without autogenous periodontal ligament graft (PDLG) in the management of human two-wall intrabony periodontal defects. Twenty-six similar two-wall intrabony periodontal defects with >or=5 mm probing depths and >or=3 mm d...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-008-0235-3
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVES:This in vitro study evaluated the effect of fiber insertion depth on antimicrobial efficacy of antimicrobial photodynamic therapy (aPDT) using a photosensitizer (PS; toluidine blue) and a red light-emitting diode (LED) in root canals infected with Enterococcus faecalis. MATERIALS AND METHODS:Single-rooted e...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-016-1948-3
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:This study investigated the effect of passive ultrasonic irrigation (PUI) on diffusion of hydroxyl ions through radicular dentine. MATERIALS AND METHODS:After chemomechanical preparation of root canals in 60 human teeth, the cementoenamel junction and the apical 3 mm of each root were covered with fast-setti...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1500-x
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVES:It is well accepted that stage-specific embryonic antigen (SSEA)-4 is an antigen that is useful to isolate adult stem cells analogous to embryonic stem cells. Therefore, in the present study, we investigated whether SSEA-4 can also be used as a marker to identify human deciduous dental pulp (D-DP) stem cells...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-014-1260-z
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVES:This study aimed to examine the electromyographic activity of superficial masseter and anterior temporal muscles during chewing gum and gummy jelly mastication in healthy subjects to reveal the difference of neuromuscular control of jaw-closing muscles, according to the food texture. MATERIALS AND METHODS:E...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2754-x
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to quantify the symmetry of the alveolar process of the maxilla and palate during the first year of life in healthy infants with the help of a semiautomatic segmentation technique. MATERIALS AND METHODS:Maxillary plaster models of seventy healthy babies at 0, 3, 6, 9, and 12 mo...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03403-4
更新日期：2020-06-24 00:00:00
abstract：OBJECTIVES:To evaluate the effects of air-blowing time and storage time on microtensile bond strength (μTBS) of universal adhesives to dentin. MATERIALS AND METHODS:Ninety flat dentin surfaces from extracted human third molars were bonded with three universal adhesives (Clearfil Universal Bond-CU; G-Premio Bond-GP; Sc...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2656-y
更新日期：2019-06-01 00:00:00
abstract：:Periodontal ligament (PDL) cells have been associated with the regulation of periodontal repair processes by the differential expression of osteoprotegerin and RANKL in response to intermittent parathyroid hormone (PTH) resulting in a modified activity of bone-resorbing osteoclasts. Here, we examined the intracellular...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-011-0541-z
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE:The objective of the study is to compare skeletal and dental changes in class II patients treated with fixed functional appliances (FFA) that pursue different biomechanical concepts: (1) FMA (Functional Mandibular Advancer) from first maxillary molar to first mandibular molar through inclined planes and (2) H...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-017-2111-5
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:The objective of this study was to evaluate the association between salivary and plaque arginine levels/ADS activities with dental caries. MATERIALS AND METHODS:A systematic search was performed as per PRISMA statement using PubMed, Scopus, Cochrane Library, and Web of Science. Published studies that invest...
journal_title：Clinical oral investigations
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00784-017-2322-9
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVES:Candida albicans is the most common fungal pathogen in humans, but other Candida species cause candidosis. Candida species display significant differences in their susceptibility to antimycotic drugs. Patients with symptomatic or erythematous oral lichen planus (OLP) commonly have Candida infection requiring...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-012-0757-6
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:Several theories have been proposed regarding the genesis of sialoliths, including the organic core theory, which suggests epithelial or bacterial etiology originating in the central core. Our aim was to use novel methodologies to analyze central areas (the core) of calculi from sialolithiasis patients. MAT...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-012-0870-6
更新日期：2013-09-01 00:00:00
abstract：:This paper attempts to identify characteristics of a longitudinal clinical study's "dropout" population (1974-1996) of patients using overdentures. This study included 395 subjects. Dropouts were identified as persons who did not respond to letters or telephone calls after participating in the study for up to 2 years,...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-003-0238-z
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate changes in saliva concentration of the inflammatory marker MRP-8/14 and the presence of some periodontitis-associated bacteria in patients with mixed dentition treated with a rigid acrylic, bonded maxillary expander. METHODS:Fifteen patients in mixed dentition treate...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03706-6
更新日期：2020-12-03 00:00:00
abstract：:The goal of the study was to develop a validated manual preparation process that conforms to the requirements of validation guidelines. Twelve dental transmission devices from various manufacturers (turbines, handpieces, and contra-angle handpieces) were artificially contaminated with bovine hemoglobin for the test. T...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-010-0425-7
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to assess current opinions, applied techniques, and materials for the restoration of endodontically treated teeth (ETT) in a nationwide survey in Germany. MATERIAL AND METHODS:Completed questionnaires from 1,648 dentists were returned (response rate 63%). RESULTS:In general, po...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1505-5
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVES:The purpose of this study is to compare pressures at the apical foramen created by conventional syringe irrigation and the GentleWave™ System, which releases high-velocity degassed irrigants to the pulp chamber and uses broad-spectrum sound energy for cleaning. MATERIALS AND METHODS:The apical pressure gene...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1632-z
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVES:This study aimed to analyse loss of enamel worn against composite, leucite glass ceramic or enamel antagonists under non-erosive and alternating or simultanuous erosive-attritive conditions. MATERIALS AND METHODS:Flat human enamel specimens were loaded (1 Hz, 300 g loading weight, each subgroup n = 12) with...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-017-2071-9
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVES:Most patients with bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) report a previous tooth extraction at the necrosis site before the diagnosis was made. At older ages, most teeth are extracted due to periodontal disease, which is per se another BP-ONJ trigger factor. The aim of this study was t...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-0974-7
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:This study compared the effects of mold material and diameter on the thickness of cured composite remnants and depth of cure (DOC) of resin-based composites (RBC). MATERIAL AND METHODS:One Polywave® curing light was used to photo-cure two shades of the same "bulk-fill" RBC in 4, 6, or 10-mm internal diameter...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1672-4
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVES:We aimed to determine the immunolocalization patterns of the interleukin (IL)-6 signaling complex in epithelialized and non-epithelialized apical lesions of endodontic origin (ALEOs). MATERIALS AND METHODS:Epithelialized (n = 8) and non-epithelialized (n = 7) ALEOs were obtained from teeth with indication o...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03738-y
更新日期：2021-01-07 00:00:00
abstract：:Aim of this investigation was to evaluate the validity and reproducibility of the universal visual scoring systems (UniViSS) on occlusal surfaces in vitro. The validity study included 65 third molars. Following to reach a UniViSS consensus diagnosis for each surface, all teeth were histologically prepared and evaluate...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-010-0390-1
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:The study aimed to evaluate the effect of internal silver coating as a countermeasure to crestal bone loss around implants with or without multiple abutment disconnections/reconnections. MATERIALS AND METHODS:Following tooth extraction, 48 implants with connected healing abutments (24 implants internally coa...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03416-z
更新日期：2021-02-01 00:00:00
abstract：OBJECTIVE:Edible oils are an empiric approach for the prevention of oral diseases. The present in situ study investigated the effect of edible oils on initial bacterial colonization of enamel surfaces. METHODS AND MATERIALS:Initial biofilm formation was performed on enamel specimens mounted on maxillary splints and ca...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-012-0734-0
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to assess the efficacy of different cleansing agents in killing mixed species biofilms on silicone facial prostheses. MATERIALS AND METHODS:Two bacterial and three yeast strains, isolated from silicone facial prostheses, were selected for the mixed species biofilms. A variety o...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1453-0
更新日期：2015-12-01 00:00:00
abstract：:We determined the effects of soluble or coated nanocrystalline hydroxyapatite paste (nano-HA) and enamel matrix derivative (EMD) on proliferation, adhesion, and migration of periodontal ligament fibroblasts (PDLs). Cultured PDLs were stimulated with nano-HA paste or EMD in a soluble form or were coated to the surface ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-011-0570-7
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVES:Symptoms of temporomandibular joint (TMJ) dysfunction can seriously compromise patients' quality of life. The aim of our study was to use magnetic resonance imaging (MRI) T2 mapping of the articular disc to determine whether T2 mapping of the TMJ disc is feasible in routine clinical imaging and to assess the...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-1154-5
更新日期：2014-09-01 00:00:00
