Abstract:
:The menstrual cycle appears to have evolved in humans and some other species to improve reproductive efficiency by enabling progesterone production without the presence of the fetus. This phenomenon is termed spontaneous decidualization. Repeated menstruation is produced in modern women because of better general health and having fewer pregnancies later in life and limiting breast feeding. The repeated breakdown of a progesterone primed endometrium releases an inflammatory cascade which appears to have short and long term adverse consequences. Repetitive modern menstruation is no longer a sign of good general and reproductive health but a harbinger of possible future health problems. Cyclical menstruation has no intrinsic biological value or necessity in modern life. Spontaneous decidualization can be prevented by using estrogen-progestin combinations or progestins on their own. Newer and safer hormonal products are now available and should become even safer in the future. Hormonal suppression of spontaneous decidualization should be encouraged in adolescent and young women as a health promotional option.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Goldstuck NDdoi
10.1016/j.mehy.2020.109955subject
Has Abstractpub_date
2020-11-01 00:00:00pages
109955eissn
0306-9877issn
1532-2777pii
S0306-9877(20)31244-5journal_volume
144pub_type
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