Abstract:
:A total of nine endolichenic fungi were isolated from the foliose lichen Parmotrema rampoddense (Nyl.) Hale. Of the nine endolichenic fungi, three taxa (Fusarium proliferatum, Nemania primolutea, Daldinia eschsholtzii) showed antibacterial activities as determined by the disk diffusion assay against ESKAPE bacterial pathogens. Fusarium proliferatum gave the most active fungal extract with zone of inhibition values of 15 mm and 19 mm against E. faecalis and S. aureus, respectively. Further chromatographic purification of the F. proliferatum ethyl acetate extract led to the isolation and identification of bis(2-ethylhexyl)terephthalate (1), acetyl tributyl citrate (2), and fusarubin (3). Acetyl tributyl citrate (2) exhibited moderate antibacterial activity against Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus.
journal_name
3 Biotechjournal_title
3 Biotechauthors
Tan MA,Castro SG,Oliva PMP,Yap PRJ,Nakayama A,Magpantay HD,Dela Cruz TEEdoi
10.1007/s13205-020-02213-5subject
Has Abstractpub_date
2020-05-01 00:00:00pages
212issue
5eissn
2190-572Xissn
2190-5738pii
2213journal_volume
10pub_type
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