Genomic release-recapture experiment in the wild reveals within-generation polygenic selection in stickleback fish.

abstract：:Addressing the intrinsic charge transport limitation of metal oxides has been of significance for pursuing viable PEC water splitting photoelectrodes. Growing a photoelectrode with conductive nanoobjects embedded in the matrix is promising for enhanced charge transport but remains a challenge technically. We herein sh...

journal_title：Nature communications

authors： Jian J,Xu Y,Yang X,Liu W,Fu M,Yu H,Xu F,Feng F,Jia L,Friedrich D,van de Krol R,Wang H

更新日期：2019-06-13 00:00:00

abstract：:Blends of electron-donating and -accepting organic semiconductors are widely used as photoactive materials in next-generation solar cells and photodetectors. The yield of free charges in these systems is often determined by the separation of interfacial electron-hole pairs, which is expected to depend on the ability o...

journal_title：Nature communications

authors： Stolterfoht M,Armin A,Shoaee S,Kassal I,Burn P,Meredith P

更新日期：2016-06-21 00:00:00

abstract：:Oxidation of bromide in aqueous environments initiates the formation of molecular halogen compounds, which is important for the global tropospheric ozone budget. In the aqueous bulk, oxidation of bromide by ozone involves a [Br•OOO-] complex as intermediate. Here we report liquid jet X-ray photoelectron spectroscopy m...

journal_title：Nature communications

authors： Artiglia L,Edebeli J,Orlando F,Chen S,Lee MT,Corral Arroyo P,Gilgen A,Bartels-Rausch T,Kleibert A,Vazdar M,Andres Carignano M,Francisco JS,Shepson PB,Gladich I,Ammann M

更新日期：2017-09-26 00:00:00

abstract：:Synthetic lethality is a promising concept in cancer research, potentially opening new possibilities for the development of more effective and selective treatments. Here, we present a computational method to predict and exploit synthetic lethality in cancer metabolism. Our approach relies on the concept of genetic min...

journal_title：Nature communications

authors： Apaolaza I,San José-Eneriz E,Tobalina L,Miranda E,Garate L,Agirre X,Prósper F,Planes FJ

更新日期：2017-09-06 00:00:00

abstract：:Single-nucleotide variants that underlie phenotypic variation can affect chromatin occupancy of transcription factors (TFs). To delineate determinants of in vivo TF binding and chromatin accessibility, we introduce an approach that compares ChIP-seq and DNase-seq data sets from genetically divergent murine erythroid c...

journal_title：Nature communications

authors： Behera V,Evans P,Face CJ,Hamagami N,Sankaranarayanan L,Keller CA,Giardine B,Tan K,Hardison RC,Shi J,Blobel GA

更新日期：2018-02-22 00:00:00

abstract：:Quantum Griffiths singularity was theoretically proposed to interpret the phenomenon of divergent dynamical exponent in quantum phase transitions. It has been discovered experimentally in three-dimensional (3D) magnetic metal systems and two-dimensional (2D) superconductors. But, whether this state exists in lower dim...

journal_title：Nature communications

authors： Zhang E,Zhi J,Zou YC,Ye Z,Ai L,Shi J,Huang C,Liu S,Lin Z,Zheng X,Kang N,Xu H,Wang W,He L,Zou J,Liu J,Mao Z,Xiu F

更新日期：2018-11-07 00:00:00

abstract：:High-dose ionizing radiation induces severe DNA damage in the epithelial stem cells in small intestinal crypts and causes gastrointestinal syndrome (GIS). Although the tumour suppressor p53 is a primary factor inducing death of crypt cells with DNA damage, its essential role in maintaining genome stability means inhib...

journal_title：Nature communications

authors： Takemura N,Kawasaki T,Kunisawa J,Sato S,Lamichhane A,Kobiyama K,Aoshi T,Ito J,Mizuguchi K,Karuppuchamy T,Matsunaga K,Miyatake S,Mori N,Tsujimura T,Satoh T,Kumagai Y,Kawai T,Standley DM,Ishii KJ,Kiyono H,Akira S,

更新日期：2014-03-18 00:00:00

abstract：:Regional differences in health-related phenotypes have been detected between and within countries. In Scotland, regions differ for a variety of health-related traits and display differences in mean lifespan of up to 7.5 years. Both genetics and lifestyle differences are potential causes of this variation. Using data o...

journal_title：Nature communications

authors： Amador C,Xia C,Nagy R,Campbell A,Porteous D,Smith BH,Hastie N,Vitart V,Hayward C,Navarro P,Haley CS

更新日期：2017-10-06 00:00:00

abstract：:A 'pseudogap' was introduced by Mott to describe a state of matter that has a minimum in the density of states at the Fermi level, deep enough for states to become localized. It can arise either from Coulomb repulsion between electrons, and/or incipient charge or spin order. Here we employ ultrafast spectroscopy to st...

journal_title：Nature communications

authors： Madan I,Kurosawa T,Toda Y,Oda M,Mertelj T,Mihailovic D

更新日期：2015-04-20 00:00:00

abstract：:Mycobacterium tuberculosis is a pathogen with a unique cell envelope including very long fatty acids, implicated in bacterial resistance and host immune modulation. FasR is a TetR-like transcriptional activator that plays a central role in sensing mycobacterial long-chain fatty acids and regulating lipid biosynthesis....

journal_title：Nature communications

authors： Lara J,Diacovich L,Trajtenberg F,Larrieux N,Malchiodi EL,Fernández MM,Gago G,Gramajo H,Buschiazzo A

更新日期：2020-07-24 00:00:00

abstract：:The demand for highly scalable, low-power devices for data storage and logic operations is strongly stimulating research into resistive switching as a novel concept for future non-volatile memory devices. To meet technological requirements, it is imperative to have a set of material design rules based on fundamental m...

journal_title：Nature communications

authors： Baeumer C,Schmitz C,Ramadan AH,Du H,Skaja K,Feyer V,Müller P,Arndt B,Jia CL,Mayer J,De Souza RA,Michael Schneider C,Waser R,Dittmann R

更新日期：2015-10-19 00:00:00

abstract：:On-surface chemical reactions hold the potential for manufacturing nanoscale structures directly onto surfaces by linking carbon atoms in a single-step reaction. To fabricate more complex and functionalized structures, the control of the on-surface chemical reactions must be developed significantly. Here, we present a...

journal_title：Nature communications

authors： Kawai S,Haapasilta V,Lindner BD,Tahara K,Spijker P,Buitendijk JA,Pawlak R,Meier T,Tobe Y,Foster AS,Meyer E

更新日期：2016-09-13 00:00:00

abstract：:Printed electronics offer a breakthrough in the penetration of information technology into everyday life. The possibility of printing electronic circuits will further promote the spread of the Internet of Things applications. Inks based on graphene have a chance to dominate this technology, as they potentially can be ...

journal_title：Nature communications

authors： Pan K,Fan Y,Leng T,Li J,Xin Z,Zhang J,Hao L,Gallop J,Novoselov KS,Hu Z

更新日期：2018-12-05 00:00:00

abstract：:Extremely metal-poor galaxies with metallicity below 10% of the solar value in the local universe are the best analogues to investigating the interstellar medium at a quasi-primitive environment in the early universe. In spite of the ongoing formation of stars in these galaxies, the presence of molecular gas (which is...

journal_title：Nature communications

authors： Shi Y,Wang J,Zhang ZY,Gao Y,Hao CN,Xia XY,Gu Q

更新日期：2016-12-09 00:00:00

abstract：:Although the changes in melting behaviour on the nanoscale have long attracted the interest of researchers, the mechanism by which nanoparticles melt remains an open problem. We report the direct observation, at atomic resolution, of surface melting in individual size-selected Au clusters (2-5 nm diameter) supported o...

journal_title：Nature communications

authors： Foster DM,Pavloudis T,Kioseoglou J,Palmer RE

更新日期：2019-06-13 00:00:00

abstract：:Cellobiohydrolase 1 from Trichoderma reesei (TrCel7A) processively hydrolyses cellulose into cellobiose. Although enzymatic techniques have been established as promising tools in biofuel production, a clear understanding of the motor's mechanistic action has yet to be revealed. Here, we develop an optical tweezers-bas...

journal_title：Nature communications

authors： Brady SK,Sreelatha S,Feng Y,Chundawat SP,Lang MJ

更新日期：2015-12-10 00:00:00

abstract：:Optical phase change materials (O-PCMs), a unique group of materials featuring exceptional optical property contrast upon a solid-state phase transition, have found widespread adoption in photonic applications such as switches, routers and reconfigurable meta-optics. Current O-PCMs, such as Ge-Sb-Te (GST), exhibit lar...

journal_title：Nature communications

authors： Zhang Y,Chou JB,Li J,Li H,Du Q,Yadav A,Zhou S,Shalaginov MY,Fang Z,Zhong H,Roberts C,Robinson P,Bohlin B,Ríos C,Lin H,Kang M,Gu T,Warner J,Liberman V,Richardson K,Hu J

更新日期：2019-09-30 00:00:00

abstract：:Magnetic resonance spectroscopy is one of the most important tools in chemical and bio-medical research. However, sensitivity limitations typically restrict imaging resolution to ~ 10 µm. Here we bring quantum control to the detection of chemical systems to demonstrate high-resolution electron spin imaging using the q...

journal_title：Nature communications

authors： Simpson DA,Ryan RG,Hall LT,Panchenko E,Drew SC,Petrou S,Donnelly PS,Mulvaney P,Hollenberg LCL

更新日期：2017-09-06 00:00:00

abstract：:Many low-thermal-conductivity (κL) crystals show intriguing temperature (T) dependence of κL: κL ∝ T-1 (crystal-like) at intermediate temperatures whereas weak T-dependence (glass-like) at high temperatures. It has been in debate whether thermal transport can still be described by phonons at the Ioffe-Regel limit. In ...

journal_title：Nature communications

authors： Luo Y,Yang X,Feng T,Wang J,Ruan X

更新日期：2020-05-22 00:00:00

abstract：:Type I CRISPR-Cas loci provide prokaryotes with a nucleic-acid-based adaptive immunity against foreign DNA. Immunity involves adaptation, the integration of ~30-bp DNA fragments, termed prespacers, into the CRISPR array as spacers, and interference, the targeted degradation of DNA containing a protospacer. Interferenc...

journal_title：Nature communications

authors： Shiriaeva AA,Savitskaya E,Datsenko KA,Vvedenskaya IO,Fedorova I,Morozova N,Metlitskaya A,Sabantsev A,Nickels BE,Severinov K,Semenova E

更新日期：2019-10-10 00:00:00

abstract：:Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeostasis. We hence conducted a randomized, double-blind, placebo-controlled trial with newly diagnosed T2D patie...

journal_title：Nature communications

authors： Zhang Y,Gu Y,Ren H,Wang S,Zhong H,Zhao X,Ma J,Gu X,Xue Y,Huang S,Yang J,Chen L,Chen G,Qu S,Liang J,Qin L,Huang Q,Peng Y,Li Q,Wang X,Kong P,Hou G,Gao M,Shi Z,Li X,Qiu Y,Zou Y,Yang H,Wang J,Xu G,

更新日期：2020-10-06 00:00:00

abstract：:Various viruses enter host cells via endocytosis, but the molecular mechanisms underlying the specific internalization pathways remain unclear. Here we show that influenza A viruses (IAVs) enter cells via redundant pathways of clathrin-mediated and clathrin-independent endocytosis, with intracellular Ca(2+) having a c...

journal_title：Nature communications

authors： Fujioka Y,Tsuda M,Nanbo A,Hattori T,Sasaki J,Sasaki T,Miyazaki T,Ohba Y

更新日期：2013-01-01 00:00:00

abstract：:The gyrotropic rotation around the equilibrium position constitutes the fundamental excitation of magnetic vortices in nanostructures. The frequency of this mode varies with material and sample geometry, but is independent of the vortex handedness and its core direction. Here, we demonstrate that this degeneracy is li...

journal_title：Nature communications

authors： Sluka V,Kákay A,Deac AM,Bürgler DE,Schneider CM,Hertel R

更新日期：2015-03-03 00:00:00

abstract：:Gluconeogenesis is a fundamental feature of hepatocytes. Whether this gluconeogenic activity is also present in malignant hepatocytes remains unexplored. A better understanding of this biological process may lead to novel therapeutic strategies. Here we show that gluconeogenesis is not present in mouse or human malign...

journal_title：Nature communications

authors： Ma R,Zhang W,Tang K,Zhang H,Zhang Y,Li D,Li Y,Xu P,Luo S,Cai W,Ji T,Katirai F,Ye D,Huang B

更新日期：2013-01-01 00:00:00

abstract：:Overcoming the restricted axonal regenerative ability that limits functional repair following a central nervous system injury remains a challenge. Here we report a regenerative paradigm that we call enriched conditioning, which combines environmental enrichment (EE) followed by a conditioning sciatic nerve axotomy tha...

journal_title：Nature communications

authors： De Virgiliis F,Hutson TH,Palmisano I,Amachree S,Miao J,Zhou L,Todorova R,Thompson R,Danzi MC,Lemmon VP,Bixby JL,Wittig I,Shah AM,Di Giovanni S

更新日期：2020-12-21 00:00:00

abstract：:The nutritional environment to which animals are exposed in early life can lead to epigenetic changes in the genome that influence the risk of obesity in later life. Here, we demonstrate that the fibroblast growth factor-21 gene (Fgf21) is subject to peroxisome proliferator-activated receptor (PPAR) α-dependent DNA de...

journal_title：Nature communications

authors： Yuan X,Tsujimoto K,Hashimoto K,Kawahori K,Hanzawa N,Hamaguchi M,Seki T,Nawa M,Ehara T,Kitamura Y,Hatada I,Konishi M,Itoh N,Nakagawa Y,Shimano H,Takai-Igarashi T,Kamei Y,Ogawa Y

更新日期：2018-02-12 00:00:00

abstract：:The equilibrium volume of a thermoresponsive polymer gel changes dramatically across a temperature due to the coil-globule transitions of the polymers. When cofacially oriented nanosheets are embedded in such a gel, the composite gel deforms at the temperature, without changing the volume, and the response time is con...

journal_title：Nature communications

authors： Yamamoto T,Masubuchi Y,Doi M

更新日期：2018-05-25 00:00:00

abstract：:In June 2015, Cassini high-resolution images of Saturn's limb southwards of the planet's hexagonal wave revealed a system of at least six stacked haze layers above the upper cloud deck. Here, we characterize those haze layers and discuss their nature. Vertical thickness of layers ranged from 7 to 18 km, and they exten...

journal_title：Nature communications

authors： Sánchez-Lavega A,García-Muñoz A,Del Río-Gaztelurrutia T,Pérez-Hoyos S,Sanz-Requena JF,Hueso R,Guerlet S,Peralta J

更新日期：2020-05-08 00:00:00

abstract：:Emerging evidence indicates that osteoclasts direct osteoblastic bone formation. MicroRNAs (miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However, whether miRNAs mediate osteoclast-directed osteoblastic bone formation is mostly unknown. Here, we show that increased osteoclastic miR-214-...

journal_title：Nature communications

authors： Li D,Liu J,Guo B,Liang C,Dang L,Lu C,He X,Cheung HY,Xu L,Lu C,He B,Liu B,Shaikh AB,Li F,Wang L,Yang Z,Au DW,Peng S,Zhang Z,Zhang BT,Pan X,Qian A,Shang P,Xiao L,Jiang B,Wong CK,Xu J,Bian Z,Liang Z,

更新日期：2016-03-07 00:00:00

abstract：:When immersed into water, most solids develop a surface charge, which is neutralized by an accumulation of dissolved counterions at the interface. Although the density distribution of counterions perpendicular to the interface obeys well-established theories, little is known about counterions' lateral organization at ...

journal_title：Nature communications

authors： Ricci M,Spijker P,Voïtchovsky K

更新日期：2014-07-16 00:00:00