Abstract:
:Ten articles published in the "Special Issue: Salicylic Acid Signalling in Plants" are summarized, in order to get a global picture about the mode of action of salicylic acid in plants, and about its interaction with other stress-signalling routes. Its ecological aspects and possible practical use are also discussed.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Janda T,Szalai G,Pál Mdoi
10.3390/ijms21072655subject
Has Abstractpub_date
2020-04-10 00:00:00issue
7issn
1422-0067pii
ijms21072655journal_volume
21pub_type
社论abstract::Ile-Ala-Val-Pro-Gly-Glu-Val-Ala (IAVPGEVA), Ile-Ala-Val-Pro-Thr-Gly-Val-Ala (IAVPTGVA) and Leu-Pro-Tyr-Pro (LPYP), three peptides deriving from soy glycinin hydrolysis, are known to regulate cholesterol metabolism in human hepatic HepG2 cells. We have recently demonstrated that the mechanism of action involves the act...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms161126029
更新日期:2015-11-16 00:00:00
abstract::A series of novel 1-(4-substitutedbenzoyl)-4-(4-chlorobenzhydryl)piperazine derivatives 5a-g was designed by a nucleophilic substitution reaction of 1-(4-chlorobenzhydryl)piperazine with various benzoyl chlorides and characterized by elemental analyses, IR and (1)H nuclear magnetic resonance spectra. Cytotoxicity of t...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms13078071
更新日期:2012-01-01 00:00:00
abstract::The plant disease Phytophthora blight, caused by the oomycete pathogen Phytophthora capsici, is responsible for major economic losses in pepper production. Microtubules have been an attractive target for many antifungal agents as they are involved in key cellular events such as cell proliferation, signaling, and migra...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20112641
更新日期:2019-05-29 00:00:00
abstract::Endothelial cells (ECs) that line the lumen of blood vessels are important players in blood vessel formation, and EC migration is a key component of the angiogenic process. Thus, identification of genes that are specifically or preferentially expressed in vascular ECs and in-depth understanding of their biological fun...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms13044920
更新日期:2012-01-01 00:00:00
abstract::Cell therapy is an innovative strategy for tissue repair, since adult stem cells could have limited regenerative ability as in the case of myocardial damage. This leads to a local contractile dysfunction due to scar formation. For these reasons, refining strategy approaches for "in vitro" stem cell commitment, prepara...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19082324
更新日期:2018-08-08 00:00:00
abstract::The members of the Burkholderia genus are characterized by high versatility and adaptability to various ecological niches. With the availability of the genome sequences of numerous species of Burkholderia, many studies have been conducted to elucidate the unique features of this exceptional group of bacteria. Genomic ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms20010121
更新日期:2018-12-29 00:00:00
abstract::Past research has demonstrated that oestrogenic compounds produce strand breaks in the DNA of sperm and lymphocytes via reactive oxygen species (ROS). In the current investigation, sperm and lymphocytes were treated in vitro with oestrogenic compounds (diethylstilboestrol, progesterone, 17β-oestradiol, noradrenaline a...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms12052783
更新日期:2011-01-01 00:00:00
abstract::Maize ZmC1 and ZmR transcription factors belong to the MYB-type and bHLH families, respectively, and control anthocyanin biosynthesis. In this study, Agrobacterium-mediated transformation was used to generate transgenic wheat plants that overexpress ZmC1 and ZmR or both, with the objective of developing anthocyanin-en...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20225806
更新日期:2019-11-19 00:00:00
abstract::The insulin signaling (IIS) pathway plays an important role in the metabolism, growth, development, reproduction, and longevity of an organism. As a key member of the IIS pathway, insulin-like growth factor binding proteins (IGFBPs) are widely distributed a family in invertebrates and vertebrates that are critical in ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms22031056
更新日期:2021-01-21 00:00:00
abstract::Periodontitis is a common disease characterized by chronic inflammation and tissue destruction of gums. Human periodontal ligament stem cells (PDLSCs), derived from the periodontium, have stem cell properties similar to those of mesenchymal stem cells. PDLSCs possess not only the potential to differentiate into other ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19123843
更新日期:2018-12-03 00:00:00
abstract::Targeting cancer cells using chimeric-antigen-receptor (CAR-)T cells has propelled adoptive T-cell therapy (ATT) to the next level. A plentitude of durable complete responses using CD19-specific CAR-T cells in patients suffering from various lymphoid malignancies resulted in the approval by the food and drug administr...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms20235942
更新日期:2019-11-26 00:00:00
abstract::Human chorionic gonadotropin (hCG) is no longer a single, omnipotent ovulation triggering option. Gonadotropin releasing hormone (GnRH) agonist, initially presented as a substitute for hCG, has led to a new era of administering GnRH agonist followed by hCG triggering. According to this new concept, GnRH agonist enable...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms18051075
更新日期:2017-05-17 00:00:00
abstract::Prior evidence indicates that homocysteine plays a role in the development of metabolic syndrome (MetS). Methylenetetrahydrofolate reductase (MTHFR) C677T and methionine synthase reductase (MTRR) A66G polymorphisms are common genetic determinants of homocysteine levels. To investigate the associations of the MTHFR C67...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms151221687
更新日期:2014-11-25 00:00:00
abstract::It has been confirmed that alternatively activated macrophages (M2) participate in tissue remodeling and fibrosis occurrence, but the effect of M2 on peritoneal fibrosis related to peritoneal dialysis (PD) hasn't been elucidated. This study was therefore conducted to assess the association between M2 and peritoneal fi...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms140510369
更新日期:2013-05-17 00:00:00
abstract:BACKGROUND:Although it has been previously demonstrated that acute inflammation can promote the tumor growth of a sub-tumorigenic dose of melanoma cells through of 5-lipoxygenase inflammatory pathway and its product leukotriene B4, and also that the peritumoral treatment with eicosapentaenoic acid and its product, leuk...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20153765
更新日期:2019-08-01 00:00:00
abstract::Benzo[a]pyrene (BaP) is a well-known carcinogen formed during the cooking process. Although BaP exposure has been implicated as one of the risk factors for lung cancer in animals and humans, there are only limited data on BaP-induced gastrointestinal cancer. Therefore, this study investigated the protective effects of...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20225533
更新日期:2019-11-06 00:00:00
abstract::A thrombotic occlusion of the vessel fed by ruptured coronary atherosclerotic plaque may result in unstable angina, myocardial infarction or death, whereas embolization from a plaque in carotid arteries may result in transient ischemic attack or stroke. The atherosclerotic plaque prone to such clinical events is terme...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms160510121
更新日期:2015-05-05 00:00:00
abstract::Cisplatin is one of the most widely used chemical drugs for anticancer treatment. Recent studies have focused on the ability of cisplatin to retain the high mobility group box 1 (HMGB1) protein in cisplatin-DNA adducts, thereby preventing its release from the nucleus. Because HMGB1 is a powerful inflammatory mediator ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms140611224
更新日期:2013-05-27 00:00:00
abstract::The Duchenne muscular dystrophy (DMD) gene has a complex expression pattern regulated by multiple tissue-specific promoters and by alternative splicing (AS) of the resulting transcripts. Here, we used an RNAi-based approach coupled with DMD-targeted RNA-seq to identify RNA-binding proteins (RBPs) that regulate splicin...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21207803
更新日期:2020-10-21 00:00:00
abstract::We prepared thermoresponsive hydrogels by mixing poly(N-isopropylacrylamide) (PNIPAAm) derivatives as the main chain components, octa-arm polyethylene glycol (PEG) as a crosslinker, and the Arg-Gly-Asp-Ser (RGDS) peptides as cell adhesion units. Human bone marrow-derived mesenchymal stem cells (hbmMSCs) were cultured ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19041253
更新日期:2018-04-21 00:00:00
abstract::The majority of the human genome is comprised of non-protein-coding genes, but the relevance of non-coding RNAs in complex diseases has yet to be fully elucidated. One class of non-coding RNAs is long non-coding RNAs or lncRNAs, many of which have been identified to play a range of roles in transcription and translati...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms22031094
更新日期:2021-01-22 00:00:00
abstract::The silk gland synthesizes and secretes a large amount of protein and stores liquid silk protein at an extremely high concentration. Interestingly, silk proteins and serine protease inhibitors are orderly arranged in the silk gland lumen and cocoon shells. Silk fiber formation and the spinning mechanism have not been ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20102491
更新日期:2019-05-20 00:00:00
abstract::Four chiral Schiff base binuclear 3d-4f complexes (NdNi, NdCu, GdNi, and GdCu) have been prepared and characterized by means of electronic and CD spectra, IR spectra, magnetic measurements, and X-ray crystallography (NdNi). A so-called artifact peak of solid state CD spectra, which was characteristic of oriented molec...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms12106966
更新日期:2011-01-01 00:00:00
abstract::The transition from pregnancy to lactation is characterized by a progressive decrease in insulin sensitivity. Propionate increases with dietary fiber consumption and has been shown to improve insulin sensitivity. Recent studies suggest that plasma odd-chain fatty acids [OCFAs; pentadecanoic acid (C15:0) and heptadecan...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21020635
更新日期:2020-01-18 00:00:00
abstract::Single nucleotide polymorphisms (SNPs) are currently the marker of choice in a variety of genetic studies. Using the high resolution melting (HRM) genotyping approach, 101 gene-based SNP markers were developed for Apostichopus japonicus, a sea cucumber species with economic significance for the aquaculture industry in...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms13067080
更新日期:2012-01-01 00:00:00
abstract::Heart disease in women remains underappreciated, underdiagnosed and undertreated. Further, although we are starting to understand some of the social and behavioral determinants for this, the biological basis for the increased rate of rise in atherosclerosis risk in women after menopause remains very poorly understand....
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms17050760
更新日期:2016-05-18 00:00:00
abstract::Salidroside (Sal) is an active ingredient that is isolated from Rhodiola rosea, which has been reported to have anti-inflammatory activities and a renal protective effect. However, the role of Sal on renal fibrosis has not yet been elucidated. Here, the purpose of the current study is to test the protective effects of...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20051103
更新日期:2019-03-04 00:00:00
abstract::Stimulation of thermogenesis in brown adipose tissue (BAT) could have far-reaching health benefits in combatting obesity and obesity-related complications. Apolipoprotein A-IV (ApoA-IV), produced by the gut and the brain in the presence of dietary lipids, is a well-known short-term satiating protein. While our previou...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms22031221
更新日期:2021-01-27 00:00:00
abstract::Antimicrobial peptides (AMPs) are molecules widespread in all branches of the tree of life that participate in host defense and/or microbial competition. Due to their positive charge, hydrophobicity and amphipathicity, they preferentially disrupt negatively charged bacterial membranes. AMPs are considered an important...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21124310
更新日期:2020-06-17 00:00:00
abstract::We report molecular dynamics simulations of confined liquid crystals using the Gay-Berne-Kihara model. Upon isobaric cooling, the standard sequence of isotropic-nematic-smectic A phase transitions is found. Upon further cooling a reentrant nematic phase occurs. We investigate the temperature dependence of the self-dif...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms13067854
更新日期:2012-01-01 00:00:00