If only I could turn back time-Regret in bereaved parents.

abstract：BACKGROUND:Malignant ectomesenchymoma (MEM) is a soft tissue tumor with heterologous rhabdomyoblastic components believed to arise from pluripotent migratory neural crest cells. To date merely 50 cases have been published and the knowledge about the course of disease and optimal treatment is limited. METHODS:Six patie...

journal_title：Pediatric blood & cancer

authors： Dantonello TM,Leuschner I,Vokuhl C,Gfroerer S,Schuck A,Kube S,Nathrath M,Bernbeck B,Kaatsch P,Pal N,Ljungman G,Bielack SS,Klingebiel T,Koscielniak E,CWS.

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:The improved survival rates for childhood acute lymphoblastic leukemia (ALL) may be jeopardized by the development of a second cancer, which has been associated with thiopurine therapy. PROCEDURE:We retrospectively analyzed three sequential Nordic Society of Paediatric Haematology and Oncology's protocols c...

journal_title：Pediatric blood & cancer

authors： Nielsen SN,Eriksson F,Rosthoej S,Andersen MK,Forestier E,Hasle H,Hjalgrim LL,Aasberg A,Abrahamsson J,Heyman M,Jónsson ÓG,Pruunsild K,Vaitkeviciené GE,Vettenranta K,Schmiegelow K

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:We sought to assess patterns of failure in pediatric patients with intracranial germ cell tumors (GCT) treated with intensity-modulated radiation therapy with dose painting (DP-IMRT). PROCEDURE:Between July 2007 and October 2013, 11 patients with localized GCT-five germinomas and six nongerminoma GCT (NGGCT...

journal_title：Pediatric blood & cancer

authors： Yang JC,Terezakis SA,Dunkel IJ,Gilheeney SW,Wolden SL

更新日期：2016-04-01 00:00:00

abstract：:We describe five cases of children who completed chemotherapy for infantile acute lymphoblastic leukemia (ALL) and soon after were diagnosed with severe T-cell, non-HIV immunodeficiency, with varying B-cell and NK-cell depletion. There was near absence of CD3(+) , CD4(+) , and CD8(+) cells. All patients developed mult...

journal_title：Pediatric blood & cancer

authors： Geerlinks AV,Issekutz T,Wahlstrom JT,Sullivan KE,Cowan MJ,Dvorak CC,Fernandez CV

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Severe pandemic influenza A (H1N1) infection can lead to acute respiratory failure (ARF) with associated high mortality. Children with malignancy may be at higher risk of H1N1-associated ARF because of underlying primary disease or immunosuppression associated with chemotherapy. PROCEDURE:We describe the cl...

journal_title：Pediatric blood & cancer

authors： Elbahlawan L,Gaur AH,Furman W,Jeha S,Woods T,Norris A,Morrison RR

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Outcomes for patients with oncologic disease and/or after hematopoietic stem cell transplant (HSCT) requiring intensive care unit admission have improved, but indications for and outcomes after extracorporeal membrane oxygenation (ECMO) support in this population are poorly characterized. PROCEDURE:We analy...

journal_title：Pediatric blood & cancer

authors： Steppan DA,Coleman RD,Viamonte HK,Hanson SJ,Carroll MK,Klein OR,Cooke KR,Spinella PC,Steiner ME,Loftis LL,Bembea MM,Pediatric ECMO (PediECMO) subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:While pediatric low-grade glioma/glioneuronal tumors (LGG/LGGNTs) are considered slow-growing, indolent tumors with excellent long-term prognosis, mortality due to the disease is not unknown. Few studies have addressed the cause of death in this population. METHODS:Retrospective review of clinicopathologic ...

journal_title：Pediatric blood & cancer

authors： Upadhyaya SA,Ghazwani Y,Wu S,Broniscer A,Boop FA,Gajjar A,Qaddoumi I

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Central nervous system irradiation (CNS-RT) has played a central role in the cure of acute lymphoblastic leukemia (ALL), but due to the risk of long-term toxicity, it is now considered a less-favorable method of CNS-directed therapy. PROCEDURES:Retrospectively, we estimated the effect of CNS involvement and...

journal_title：Pediatric blood & cancer

authors： Taskinen M,Oskarsson T,Levinsen M,Bottai M,Hellebostad M,Jonsson OG,Lähteenmäki P,Schmiegelow K,Heyman M

更新日期：2017-02-01 00:00:00

abstract：:We evaluated the effects of body mass index (BMI) on the risk of thromboembolism (TE) in children (<18 years) with hematological malignancies during the period 1990-2009 (n = 359). Obesity was prevalent in 12% of patients: 6% versus 17% prior to and after the year 2000 (P = 0.02). Sixty-one (17%) patients developed TE...

journal_title：Pediatric blood & cancer

authors： Tuckuviene R,Christensen AL,Chan AK,Athale U

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Children with cancer may be at an increased risk of infection with hepatitis B virus (HBV) when levels of hepatitis B antibodies are reduced owing to chemotherapy-induced immunosuppression. This study evaluated the changes in HBV antibody status and HBV infections after chemotherapy in children with acute ly...

journal_title：Pediatric blood & cancer

authors： Choi YB,Lee NH,Yi ES,Kim YJ,Koo HH

更新日期：2019-12-01 00:00:00

abstract：:Post-transplant lymphoproliferative disease (PTLPD), due to the reactivation of Epstein-Barr virus (EBV), is a serious complication. The risk of the disorder increases with T-cell depletion methods, mismatched hematopoietic stem cell transplantation (HSCT), graft-versus-host disease (GVHD), and immunosuppression. In c...

journal_title：Pediatric blood & cancer

authors： Kasow KA,Leung W,Horwitz EM,Woodard P,Handgretinger R,Hale GA

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Sickle cell disease (SCD) is an inherited blood disorder characterized by a chronic hemolytic anemia that can contribute to fatigue and global cognitive impairment in patients. The study objective was to report on the feasibility, reliability, and validity of the PedsQL™ Multidimensional Fatigue Scale in SCD...

journal_title：Pediatric blood & cancer

authors： Panepinto JA,Torres S,Bendo CB,McCavit TL,Dinu B,Sherman-Bien S,Bemrich-Stolz C,Varni JW

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The prognostic significance of having extraskeletal (EES) versus skeletal Ewing sarcoma (ES) in the setting of modern chemotherapy protocols is unknown. The purpose of this study was to compare the clinical characteristics, biologic features, and outcomes for patients with EES and skeletal ES. METHODS:Patie...

journal_title：Pediatric blood & cancer

authors： Cash T,McIlvaine E,Krailo MD,Lessnick SL,Lawlor ER,Laack N,Sorger J,Marina N,Grier HE,Granowetter L,Womer RB,DuBois SG

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Resource-rich countries tend to have a higher incidence of childhood acute lymphoblastic leukemia (ALL), whereas lower rates are seen in more deprived countries. This study describes the incidence of childhood acute leukemia in Brazil, an upper middle-income country, based on data from 16 population-based ca...

journal_title：Pediatric blood & cancer

authors： de Souza Reis R Sr,de Camargo B,de Oliveira Santos M,de Oliveira JM,Azevedo Silva F,Pombo-de-Oliveira MS

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Although intra-retinal tumor has long been staged presurgically according to the Reese-Ellsworth (R-E) system, retinoblastoma differs from other pediatric neoplasms in never having had a widely accepted classification system that encompasses the entire spectrum of the disease. Comparisons among studies that ...

journal_title：Pediatric blood & cancer

authors： Chantada G,Doz F,Antoneli CB,Grundy R,Clare Stannard FF,Dunkel IJ,Grabowski E,Leal-Leal C,Rodríguez-Galindo C,Schvartzman E,Popovic MB,Kremens B,Meadows AT,Zucker JM

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Only a few studies have assessed cardiovascular risk factors (CRFs) in childhood cancer survivors. We determined the prevalence of CRFs in long-term survivors of acute lymphoblastic leukemia (ALL) and Wilms tumor. PROCEDURE:Adult survivors of ALL and Wilms tumor treated with radiotherapy and chemotherapy (R...

journal_title：Pediatric blood & cancer

authors： Geenen MM,Bakker PJ,Kremer LC,Kastelein JJ,van Leeuwen FE

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Neuroblastoma (NB) is cytogenetically characterized by a number of non-random events. However, knowledge is limited concerning the timing of occurrence and inter-action of many of these events. METHODS:Karyotypic patterns were obtained from a study group of 49 NB tumors that had been analyzed by conventiona...

journal_title：Pediatric blood & cancer

authors： Betts DR,Cohen N,Leibundgut KE,Kühne T,Caflisch U,Greiner J,Traktenbrot L,Niggli FK

更新日期：2005-02-01 00:00:00

abstract：:We report two survivors of Wilms tumor (WT) who developed inflammatory myofibroblastic tumor (IMT). The first patient had IMT in the mainstem bronchus 1 year after WT therapy that included vincristine, dactinomycin, doxorubicin (VDA) and whole lung radiation therapy (XRT). The second patient had IMT in the cecum 7 yea...

journal_title：Pediatric blood & cancer

authors： Ortiz MV,Rossi CT,Hill DA,Guzzetta PC,Qureshi F,Dome JS

更新日期：2015-06-01 00:00:00

abstract：:Aplastic anemia (AA) is an immune-mediated disease. Although most patients are responsive to immunosuppressive therapy (IST) with a combination of anti-thymocyte globulin (ATG) and cyclosporine (CsA), some patients relapse or are refractory to IST. Sirolimus (rapamysin) inhibits the serine-threonine kinase mammalian t...

journal_title：Pediatric blood & cancer

authors： He G,Zhang X,Wu D,Sun A,Wang X

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PHT) may be the leading cause of death in β-thalassemia patients; however, its pathophysiologic mechanisms are still unclear. Recent studies indicate that asymmetric dimethylarginine (ADMA) plays a role in the initiation and progression of a variety of diseases, especially the cardiov...

journal_title：Pediatric blood & cancer

authors： Mohamed el-S,Ibrahim B,Amr D,Noha el-K,Mokhtar M

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Cancer is the second most common cause of childhood deaths in the United Kingdom and infection contributes to a quarter of all cancer-related deaths. This study aimed to estimate the risk, aetiology and outcome of bloodstream bacterial and fungal infections in children with cancer within a geographically def...

journal_title：Pediatric blood & cancer

authors： Calton EA,Le Doaré K,Appleby G,Chisholm JC,Sharland M,Ladhani SN,CABIN Participants.

更新日期：2014-07-01 00:00:00

abstract：:Hemoglobin O-Arab [Beta 121 Glu → Lys] (Hb O-Arab) is a rare abnormal hemoglobin (Hb) whose clinical and hematological features have been described in adults but not in children. We report three children, 9, 12, and 36 months of age, with homozygous Hb O-Arab and assess the value of supplementary folic acid as treatme...

journal_title：Pediatric blood & cancer

authors： Dror S

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Influenza is a health risk to children receiving chemotherapy for cancer. An absolute lymphocyte count (ALC) >1,000 cells/mm(3) has been associated with the ability to produce an immune response to influenza vaccine during chemotherapy. However, clinical efficacy of influenza vaccination during chemotherapy ...

journal_title：Pediatric blood & cancer

authors： Choi DK,Fuleihan RL,Walterhouse DO

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Drug shortages require clinical teams to decide how to allocate drugs in limited supply among their patients. Ethical frameworks are invaluable for promoting rational approaches to drug distribution, but gaps remain between ethical theory and clinical application. The goal of this work was to explore how dec...

journal_title：Pediatric blood & cancer

authors： Russell HV,Bernhardt MB,Berg S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The Kids ITP Tools (KIT) is a disease-specific measure of health-related quality of life for children with immune thrombocytopenia (ITP). To facilitate use in international trials it has been cross-culturally adapted for France, Germany, the United Kingdom and Uruguay. This study assessed the validity and re...

journal_title：Pediatric blood & cancer

authors： Klaassen RJ,Blanchette V,Burke TA,Wakefield C,Grainger JD,Gaedicke G,Riedlinger A,Dufort G,Citrin E,Reguerre Y,Pellier I,Curtis C,Young NL

更新日期：2013-01-01 00:00:00

abstract：:Although limited data are available about cyclophosphamide disposition in patients with renal insufficiency, nothing has been reported in anephric patients. We characterized cyclophosphamide pharmacokinetics in an anephric child with bilateral Wilms tumor, both on (day 1) and off (day 2) hemodialysis. The median cyclo...

journal_title：Pediatric blood & cancer

authors： McCune JS,Adams D,Homans AC,Guillot A,Iacono L,Stewart CF

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:The rate of bacterial infections in children with sickle cell disease (SCD) has decreased in recent years, mainly due to penicillin prophylaxis and vaccination. OBJECTIVES:To determine the rate of severe bacterial infection (SBI) in a cohort of children with SCD and to describe low-risk factors for confir...

journal_title：Pediatric blood & cancer

authors： Rincón-López EM,Navarro Gómez ML,Hernández-Sampelayo Matos T,Saavedra-Lozano J,Aguilar de la Red Y,Hernández Rupérez B,Cela de Julián E,RETRO-DREP Study Group.

更新日期：2019-06-01 00:00:00

abstract：:Osteoporosis and osteopenia are long-term side effects of bone marrow transplant (BMT). The purpose of this study was to determine the prevalence of bone mineral density (BMD) abnormalities in pediatric patients prior to BMT. Forty-four pediatric patients were evaluated with DEXA scans. The average Z-score was -0.37. ...

journal_title：Pediatric blood & cancer

authors： Klopfenstein KJ,Clayton J,Rosselet R,Kerlin B,Termuhlen A,Gross T

更新日期：2009-10-01 00:00:00

abstract：:Opportunities for cancer prevention in adolescents range from limitation of sun exposure to the use of human papillomavirus vaccines. Those who develop malignant disease experience longer waiting times for diagnosis and treatment than do children, especially when referred to adult treatment centers, and they are less ...

journal_title：Pediatric blood & cancer

authors： Barr RD,Greenberg ML

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Deaths during induction chemotherapy for pediatric acute lymphoblastic leukemia (ALL) account for one-tenth of ALL-associated mortality and half of ALL treatment-related mortality. We sought to ascertain patient- and hospital-level factors associated with induction mortality. PROCEDURE:We performed a retros...

journal_title：Pediatric blood & cancer

authors： Seif AE,Fisher BT,Li Y,Torp K,Rheam DP,Huang YS,Harris T,Shah A,Hall M,Fieldston ES,Kavcic M,Vujkovic M,Bailey LC,Kersun LS,Reilly AF,Rheingold SR,Walker DM,Aplenc R

更新日期：2014-05-01 00:00:00