Increased prevalence of risk factors for cardiovascular disease in long-term survivors of acute lymphoblastic leukemia and Wilms tumor treated with radiotherapy.

abstract：:As increasing numbers of childhood cancer patients are surviving, the long-term complications of the disease and its treatment have become ever more increasingly important. Reduced bone mineral density and increased fracture risk have been reported during and after treatment of children with cancer. The causes of oste...

journal_title：Pediatric blood & cancer

authors： van der Sluis IM,van den Heuvel-Eibrink MM

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:The presence of central nervous system (CNS) disease in pediatric acute myeloid leukemia (AML) is often thought to confer a worse prognosis. This study examined the outcome of children with AML who had CNS disease at diagnosis. METHODS:Patients enrolled on Children's Cancer Group protocols 2861, 2891, 2941,...

journal_title：Pediatric blood & cancer

authors： Johnston DL,Alonzo TA,Gerbing RB,Lange BJ,Woods WG

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The early effects of childhood acute lymphoblastic leukemia (ALL) include decreased physical function, bone mineral density (BMD/g/cm2 ), and health-related quality of life (HRQL). We assessed the capacity of a physical therapy and motivation-based intervention, beginning after diagnosis and continuing throu...

journal_title：Pediatric blood & cancer

authors： Cox CL,Zhu L,Kaste SC,Srivastava K,Barnes L,Nathan PC,Wells RJ,Ness KK

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Children with sickle cell disease (SCD) and abnormal transcranial Doppler (TCD) ultrasonography have a high risk of stroke, but this risk is greatly reduced when chronic transfusion therapy is administered. The change in TCD velocities during chronic transfusion therapy and rate and frequency of normalizatio...

journal_title：Pediatric blood & cancer

authors： Kwiatkowski JL,Yim E,Miller S,Adams RJ,STOP 2 Study Investigators.

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Adolescents with acute lymphoblastic leukaemia (ALL) have languished in the shadow of success of the outcome of therapy in childhood ALL. Their treatment has always been incorporated into either paediatric or adult clinical trials depending on the mode of referral and hence there is a need to address an age ...

journal_title：Pediatric blood & cancer

authors： Ramanujachar R,Richards S,Hann I,Goldstone A,Mitchell C,Vora A,Rowe J,Webb D

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Patient transition readiness self-assessment tools and investigation into patient and parent perceptions of the transition process from pediatric to adult care models have informed recognition of gaps in care, particularly for those with chronic disease. Implementation of a longitudinal transition process wi...

journal_title：Pediatric blood & cancer

authors： Croteau SE,Padula M,Quint K,D'Angelo L,Neufeld EJ

更新日期：2016-03-01 00:00:00

abstract：:The efficacy of hydroxyurea in hemoglobin SC (HbSC) patients is not well documented. We describe the long-term response to hydroxyurea in children with clinically severe HbSC. In 15 patients, hydroxyurea resulted in a significant increase in mean corpuscular volume (MCV) and fetal hemoglobin (HbF) and a significant de...

journal_title：Pediatric blood & cancer

authors： Yates AM,Dedeken L,Smeltzer MP,Lebensburger JD,Wang WC,Robitaille N

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Pediatric aggressive fibromatosis (AF) is a rare, benign tumor with locally infiltrative growth. Therefore, how to prevent reoccurrence while maintaining the mandible contour and continuity as much as possible is very important when the mandible is involved. PROCEDURE:We selected 10 pediatric patients with ...

journal_title：Pediatric blood & cancer

authors： Zhou Y,Zhang Z,Fu H,Qiu W,Wang L,He Y

更新日期：2012-10-01 00:00:00

abstract：:Twenty-eight patients were maintained on subcutaneous immunoglobulin replacement for persistent B-cell aplasia and agammaglobulinemia following CD19-targeted chimeric antigen receptor T-cell therapy for B-cell lymphoblastic leukemia. Patients were transitioned from intravenous to subcutaneous immunoglobulin replacemen...

journal_title：Pediatric blood & cancer

authors： Arnold DE,Maude SL,Callahan CA,DiNofia AM,Grupp SA,Heimall JR

更新日期：2020-03-01 00:00:00

abstract：:Global variations in the incidence of pediatric cancers have been described; however, the causes of such differences are not known. We investigated the relationship between the incidence of embryonal tumors and human development index on a global scale. Increasing incidence of neuroblastoma correlates significantly wi...

journal_title：Pediatric blood & cancer

authors： Kamihara J,Ma C,Fuentes Alabi SL,Garrido C,Frazier AL,Rodriguez-Galindo C,Orjuela MA

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Langerhans cell histiocytosis is a rare disease of unknown etiology. We wanted to assess the population-based incidence of LCH in a well-defined cohort of children. METHODS:We identified all children <15-years old treated with LCH during the 10 years period 1992-2001 at the Department of Pediatrics, Karolin...

journal_title：Pediatric blood & cancer

authors： Stålemark H,Laurencikas E,Karis J,Gavhed D,Fadeel B,Henter JI

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Choroid plexus tumors (CPT) are rare, and predominate in early childhood. An association with the Li-Fraumeni syndrome (LFS) has been reported, but the biological and clinical implications of this association remain poorly defined. We have investigated the clinical features and overall survival of all CPT pa...

journal_title：Pediatric blood & cancer

authors： Gozali AE,Britt B,Shane L,Gonzalez I,Gilles F,McComb JG,Krieger MD,Lavey RS,Shlien A,Villablanca JG,Erdreich-Epstein A,Dhall G,Jubran R,Tabori U,Malkin D,Finlay JL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Ewing sarcoma (ES), a highly aggressive tumor of children and young adults, is characterized most commonly by an 11;22 chromosomal translocation that fuses EWSR1 located at 22q12 with FLI1, coding for a member of the ETS family of transcription factors. Although genetic changes in ES have been extensively re...

journal_title：Pediatric blood & cancer

authors： Nestheide S,Bridge JA,Barnes M,Frayer R,Sumegi J

更新日期：2013-09-01 00:00:00

abstract：:We report two second malignant neoplasms (SMNs) of the parotid gland. Patient 1 was initially diagnosed with precursor B-cell lymphoblastic lymphoma of the scalp. Eight years after her initial diagnosis she presented with a small, painless mass in the region of her parotid gland. Patient 2 was diagnosed with pre-B-cel...

journal_title：Pediatric blood & cancer

authors： Savelli SL,Klopfenstein KJ,Termuhlen AM

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Incidence of venous thromboembolism (VTE) in children is reported to be increasing. We examined thrombophilia testing results in children with VTE that presented in inpatient and outpatient settings to explore patterns of thrombophilia testing. PROCEDURE: PATIENTS/METHODS:Children, ages 0-20 years with VTE...

journal_title：Pediatric blood & cancer

authors： Mahajerin A,Obasaju P,Eckert G,Vik TA,Mehta R,Heiny M

更新日期：2014-03-01 00:00:00

abstract：:Hepatic sinusoidal obstructive syndrome (HSOS) is a frequent complication in patients undergoing haematopoietic stem cell transplant (HSCT), and more rarely, in paediatric patients receiving conventional chemotherapy for solid tumours. Its diagnosis relies on a combination of clinical signs and symptoms such as hepato...

journal_title：Pediatric blood & cancer

authors： De Leonardis F,Koronica R,Bruno SD,Santoro N

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Bleomycin is associated with pulmonary toxic side effects including pneumonitis and pulmonary fibrosis. We evaluated the prevalence of long-term pulmonary function abnormalities in children receiving bleomycin therapy in the context of current chemotherapeutic regimens. METHODS:A retrospective review of pat...

journal_title：Pediatric blood & cancer

authors： De A,Guryev I,LaRiviere A,Kato R,Wee CP,Mascarenhas L,Keens TG,Venkatramani R

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Right hemicolectomy (RHC) in patients with neuroendocrine tumors (NET) of the appendix has been advocated for tumors more than 2 cm, or with mesoappendix/vessel invasion, or with raised mitotic activity. No study demonstrated prolonged survival with RHC over appendectomy alone. The aim of this study was to c...

journal_title：Pediatric blood & cancer

authors： de Lambert G,Lardy H,Martelli H,Orbach D,Gauthier F,Guérin F

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:More than 60% of children with acute myeloid leukemia (AML) become long-term survivors. Most are cured using chemotherapy without hematopoietic stem cell transplantation (HSCT). We report on pubertal development and compare self-reported parenthood among AML survivors and their siblings. PROCEDURE:We includ...

journal_title：Pediatric blood & cancer

authors： Molgaard-Hansen L,Skou AS,Juul A,Glosli H,Jahnukainen K,Jarfelt M,Jónmundsson GK,Malmros J,Nysom K,Hasle H,Nordic Society of Pediatric Hematology and Oncology.

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Retinoblastoma (Rb) is the most common intraocular primary malignancy in children. In industrialised countries, the cure rate is about 95%. We present the results of a prospective study on the management of Rb in the paediatric oncology unit of Gabriel Touré Teaching Hospital and African Institute of Tropica...

journal_title：Pediatric blood & cancer

authors： Traoré F,Sylla F,Togo B,Kamaté B,Diabaté K,Diakité AA,Diall H,Dicko F,Sylla M,Bey P,Desjardins L,Gagnepain-Lacheteau A,Coze C,Harif M,Doz F

更新日期：2018-08-01 00:00:00

abstract：:Osteosarcoma is the most common bone tumor in children and young adults, with few advances in survival and treatment, especially for metastatic disease, in the last 30 years. Recently, immunotherapy has begun to show promise in various adult cancers, but the utility of this approach for osteosarcoma remains relatively...

journal_title：Pediatric blood & cancer

authors： Wedekind MF,Wagner LM,Cripe TP

更新日期：2018-09-01 00:00:00

abstract：:Adherence is a critical consideration in ongoing efforts to improve outcomes among adolescents and young adults (AYAs) with cancer. In this narrative review, we embed existing conceptualizations of adherence within a developmental context to provide a novel vantage point from which to examine this important issue. App...

journal_title：Pediatric blood & cancer

authors： Vandermorris A,Sampson L,Korenblum C

更新日期：2020-04-01 00:00:00

abstract：:Time-to-antibiotic administration (TTA) has been suggested as a quality-of-care (QOC) measure for pediatric oncology patients with febrile neutropenia (FN). Unknown, however, is to what extent pediatric oncology centers utilize TTA. Therefore, we designed and administered an electronic survey (68% response rate) of pr...

journal_title：Pediatric blood & cancer

authors： McCavit TL,Winick N

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Drug shortages require clinical teams to decide how to allocate drugs in limited supply among their patients. Ethical frameworks are invaluable for promoting rational approaches to drug distribution, but gaps remain between ethical theory and clinical application. The goal of this work was to explore how dec...

journal_title：Pediatric blood & cancer

authors： Russell HV,Bernhardt MB,Berg S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Prophylactic use of cranial radiation therapy (CRT) in young children with acute lymphoblastic leukemia (ALL) is associated with significant long-term morbidity. Therefore, current treatment protocols for pediatric B-precursor ALL have abandoned prophylactic CRT in favor of intrathecal chemotherapy, combined...

journal_title：Pediatric blood & cancer

authors： Nathan PC,Maze R,Spiegler B,Greenberg ML,Weitzman S,Hitzler JK

更新日期：2004-01-01 00:00:00

abstract：:2-Chlorodeoxyadenosine (2-CdA) has been successfully used in children to treat refractory Langerhans cell histiocytosis and juvenile xanthogranuloma (JXG) as salvage therapy. Although 2-CdA is generally well-tolerated, with temporary myelosuppression as the primary dose-limiting toxicity, prolonged myelosuppressive, a...

journal_title：Pediatric blood & cancer

authors： Yamada K,Yasui M,Sawada A,Inoue M,Nakayama M,Kawa K

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Based on the presumed clinical similarity between the two most severe sickle cell disease (SCD) genotypes, hemoglobin (Hb) Sβ0 thalassemia and HbSS, randomized controlled trials (RCTs) have included both genotypes. Our group has demonstrated that healthcare providers inadequately distinguish the two diagnose...

journal_title：Pediatric blood & cancer

authors： Day ME,Rodeghier M,DeBaun MR

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:About one-third of patients with rhabdomyosarcoma relapse despite appropriate treatment and experience a poor outcome. Little meaningful improvement in the outcome of this disease has been observed over the last 30 years. There is no clear international recommendation concerning the use of salvage chemotherapy ...

journal_title：Pediatric blood & cancer

authors： Winter S,Fasola S,Brisse H,Mosseri V,Orbach D

更新日期：2015-11-01 00:00:00

abstract：:In Mexico, childhood cancer incidence and mortality have increased in the last decade. Through government actions since 2005, the Popular Medical Insurance (PMI) program for childhood cancer was created. The objective of PMI was to offer early cancer diagnosis, standardized treatment regimens, and numerous pediatric o...

journal_title：Pediatric blood & cancer

authors： Rivera-Luna R,Zapata-Tarres M,Shalkow-Klincovstein J,Velasco-Hidalgo L,Olaya-Vargas A,Finkelstein-Mizrahi N,Cárdenas-Cardós R,Aguilar-Ortiz MR

更新日期：2017-06-01 00:00:00

abstract：:A major hallmark of NF1 is the development of benign tumors, including peripheral neurofibromas, plexiform neurofibromas, gliomas of the optic tract, other low grade gliomas, and pheochromocytomas. Hepatoblastoma have not been previously reported in patients with neurofibromatosis type 1. We present a case of a 9-mont...

journal_title：Pediatric blood & cancer

authors： Uçar C,Calişkan U,Toy H,Günel E

更新日期：2007-09-01 00:00:00