Socioeconomic status and global variations in the incidence of neuroblastoma: call for support of population-based cancer registries in low-middle-income countries.

abstract：:We report successful bone marrow transplantation in an 11-year-old male with chronic myeloid leukemia from his HLA-identical sibling selected by preimplantation HLA testing. Because collection of cord blood failed, the transplantation was performed when the donor reached the age of 19 months, and sufficient bone marro...

journal_title：Pediatric blood & cancer

authors： Goussetis E,Constantoulakis P,Kitra V,Peristeri I,Mastrominas M,Baka M,Papadimitropoulos M,Karamolegos C,Paisiou A,Vasilatou-Kosmidis H,Graphakos S

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Primary mediastinal germ cell tumors (GCTs) are rare in children and still represent a challenge for both adult and pediatric oncologists because of their worse outcome compared to their gonadal counterpart. PROCEDURE:Prospectively collected data concerning patients enrolled in the Italian Association of Pe...

journal_title：Pediatric blood & cancer

authors： De Pasquale MD,Crocoli A,Conte M,Indolfi P,D'Angelo P,Boldrini R,Terenziani M,Inserra A

更新日期：2016-05-01 00:00:00

abstract：:With the increasing number of long-term survivors of childhood cancer, there continues to be a critical need for development and implementation of evidence-based recommendations for clinical follow-up. In order to establish and maintain health-related follow-up guidelines, it is important to recognize the attributes o...

journal_title：Pediatric blood & cancer

authors： Hawkins MM,Robison LL

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:While pediatric low-grade glioma/glioneuronal tumors (LGG/LGGNTs) are considered slow-growing, indolent tumors with excellent long-term prognosis, mortality due to the disease is not unknown. Few studies have addressed the cause of death in this population. METHODS:Retrospective review of clinicopathologic ...

journal_title：Pediatric blood & cancer

authors： Upadhyaya SA,Ghazwani Y,Wu S,Broniscer A,Boop FA,Gajjar A,Qaddoumi I

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Fever in neutropenic (FN) patients requires immediate broad-spectrum antibiotics, however, such patients do not represent a homogeneous population and the majority of them are at low risk of developing complication. Gatifloxacin (GA) is an alternative, though it has not been thoroughly studied in Pediatrics ...

journal_title：Pediatric blood & cancer

authors： Petrilli A,Altruda Carlesse F,Alberto Pires Pereira C

更新日期：2007-10-15 00:00:00

abstract：:Chronic granulomatous disease (CGD) is an immune deficiency characterized by defective neutrophil function and increased risk of life-threatening infections. Allogeneic hematopoietic cell transplantation is curative for CGD, and conditioning regimen impacts transplant-related outcomes. We report a single-center prospe...

journal_title：Pediatric blood & cancer

authors： Bhatt ST,Schulz G,Hente M,Slater A,Murray L,Shenoy S,Bednarski JJ

更新日期：2020-01-01 00:00:00

abstract：:Spermatogonial stem cells open novel strategies for preservation of testicular tissue and fertility preservation in boys and men exposed to gonadotoxic therapies. This review provides an update on the physiology of spermatogonial stem cells in rodent and primate testes. Species-specific differences must be considered ...

journal_title：Pediatric blood & cancer

authors： Schlatt S,Ehmcke J,Jahnukainen K

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The prevalence of nausea and vomiting after receipt of intrathecal methotrexate (IT-MTX) in pediatric oncology patients is unknown. METHODS:Patients (4-18 years) about to receive IT-MTX were eligible to participate in this prospective, observational study. Patients received antiemetics as prescribed by thei...

journal_title：Pediatric blood & cancer

authors： Flank J,Nadeem K,Moledina S,Khanna M,Schindera C,Punnett A,Dupuis LL

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Hemophagocytic Lymphohistiocytosis (HLH) is characterized by uncontrolled inflammation that is generally fatal without immune modulating chemotherapy. At Texas Children's Hospital, we have observed significant central nervous system (CNS) toxicity in several patients treated for HLH according to the Histiocy...

journal_title：Pediatric blood & cancer

authors： Thompson PA,Allen CE,Horton T,Jones JY,Vinks AA,McClain KL

更新日期：2009-05-01 00:00:00

abstract：:Ovarian tumors have a low incidence in childhood, accounting for 1% of malignancies within the ages of 0-17 years. Small cell carcinoma of the ovary is a rare histology and historically has a poor prognosis. We report a case of an 11-year-old female diagnosed with small cell carcinoma of the ovary and hypercalcemia (S...

journal_title：Pediatric blood & cancer

authors： Martinez-Borges AR,Petty JK,Hurt G,Stribling JT,Press JZ,Castellino SM

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:Fever in severe chemotherapy-induced neutropenia (FN) is the most frequent manifestation of a potentially lethal complication of current intensive chemotherapy regimens. This study aimed at establishing models predicting the risk of FN, and of FN with bacteremia, in pediatric cancer patients. METHODS:In a s...

journal_title：Pediatric blood & cancer

authors： Wicki S,Keisker A,Aebi C,Leibundgut K,Hirt A,Ammann RA

更新日期：2008-12-01 00:00:00

abstract：:An 8-year old child had a pelvic MYCN-nonamplified neuroblastoma (NB) with retroperitoneal nodal extension. Multi-modality therapy achieved complete remission (CR). Small recurrences confined to left supraclavicular nodes were treated with surgery alone at 4.9, 6.5, 7.5, 9.5, and 12.9 years from diagnosis. Monitoring ...

journal_title：Pediatric blood & cancer

authors： Kushner BH,Laquaglia MP,Kramer K,Modak S,Cheung NK

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:The goals of this study included: (1) Identification of factors prognostic for event-free survival (EFS) and overall survival (OS), and (2) Definition of risk groups for risk adapted therapy in children with Hodgkin disease (HD). PROCEDURE:From 1991 to 2003, 69 children with newly diagnosed, untreated biops...

journal_title：Pediatric blood & cancer

authors： Oguz A,Karadeniz C,Okur FV,Citak EC,Pinarli FG,Bora H,Akyurek N

更新日期：2005-10-15 00:00:00

abstract：:In this retrospective study of patients with overt orbital retinoblastoma, we evaluated minimally disseminated disease (MDD) in bone marrow and cerebrospinal fluid (CSF) using CRX and/or GD2 synthase as markers. Ten patients were evaluated-five (50%) at diagnosis and five upon relapse. MDD was detected in four cases (...

journal_title：Pediatric blood & cancer

authors： Aschero R,Torbidoni A,Sampor C,Laurent V,Zugbi S,Winter U,Lubieniecki F,Alonso D,Schaiquevich P,Chantada GL

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:ABT-751, an orally bioavailable sulfonamide, binds beta-tubulin to inhibit microtubule polymerization. We described response and event-free survival (EFS) in children with neuroblastoma and other solid tumors receiving ABT-751, assessed in vitro cytotoxicity of ABT-751 and evaluated the effect of ABT-751 on ...

journal_title：Pediatric blood & cancer

authors： Meany HJ,Sackett DL,Maris JM,Ward Y,Krivoshik A,Cohn SL,Steinberg SM,Balis FM,Fox E

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The high cost, coupled with the need for continuous infusion, renders Desferrioxamine (DFO), a non-feasible option for iron-chelation in a large majority of patients with β-thalassemia major in developing countries. Monotherapy with deferiprone (DFP) or deferasirox (DFX) may not always attain optimal control...

journal_title：Pediatric blood & cancer

authors： Totadri S,Bansal D,Bhatia P,Attri SV,Trehan A,Marwaha RK

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:M6620 is a novel inhibitor of the DNA damage repair enzyme ATR, and has potentiated the activity of cisplatin and irinotecan in non-small cell lung cancer and colon cancer xenografts, respectively. PROCEDURES:M6620 was tested in vitro at concentrations ranging from 1.0 nM to 10.0 μM and at 75 nM in combinat...

journal_title：Pediatric blood & cancer

authors： Kurmasheva RT,Kurmashev D,Reynolds CP,Kang M,Wu J,Houghton PJ,Smith MA

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Pheochromocytomas (PCs) are neuroendocrine tumors arising from the chromaffin cells of the adrenal gland, and paragangliomas (PGLs) are their extra-adrenal counterparts arising from ganglia along the sympathetic/parasympathetic chain. Surgery is the cornerstone of treatment. A sporatic or inherited germline ...

journal_title：Pediatric blood & cancer

authors： Virgone C,Andreetta M,Avanzini S,Chiaravalli S,De Pasquale D,Crocoli A,Inserra A,D'Angelo P,Alaggio R,Opocher G,Cecchetto G,Ferrari A,Bisogno G,Dall'Igna P

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:We report on the treatment of children and adolescents with acute lymphoblastic leukemia (ALL) in first relapse. The protocol focused on: (1) Intensive chemotherapy preceding allogeneic stem cell transplantation (SCT) in early bone marrow relapse; (2) Rotational chemotherapy in late relapse, without donor; (...

journal_title：Pediatric blood & cancer

authors： van den Berg H,de Groot-Kruseman HA,Damen-Korbijn CM,de Bont ES,Schouten-van Meeteren AY,Hoogerbrugge PM

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Symptoms of epidural compression (SEC) in children with neuroblastoma (particularly infants) may be misinterpreted, leading to delay in diagnosis. PATIENTS AND METHODS:Clinical, imaging and follow-up data of 34 infants with neuroblastoma and SEC diagnosed between 2000 and 2011 at Italian AIEOP centers were ...

journal_title：Pediatric blood & cancer

authors： De Bernardi B,Quaglietta L,Haupt R,Castellano A,Tirtei E,Luksch R,Mastrangelo S,Viscardi E,Indolfi P,Cellini M,Tamburini A,Erminio G,Gandolfo C,Sorrentino S,Vetrella S,Gigliotti AR

更新日期：2014-08-01 00:00:00

abstract：:We present three pediatric patients with BRAFV600E mutant high-grade gliomas treated by vemurafenib on a nominative authorization level at our institution. One patient with anaplastic ganglioglioma experienced confirmed partial tumor response and significant clinical improvement and she is alive 20 months after start ...

journal_title：Pediatric blood & cancer

authors： Bautista F,Paci A,Minard-Colin V,Dufour C,Grill J,Lacroix L,Varlet P,Valteau-Couanet D,Geoerger B

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Dexamethasone is more efficacious than prednisone in the treatment of acute lymphoblastic leukemia (ALL), but has also been associated with greater toxicity. We compared neuropsychological outcomes for patients treated on DFCI ALL Consortium Protocol 00-01, which included a randomized comparison of the two s...

journal_title：Pediatric blood & cancer

authors： Waber DP,McCabe M,Sebree M,Forbes PW,Adams H,Alyman C,Sands SA,Robaey P,Romero I,Routhier MÈ,Girard JM,Sallan SE,Silverman LB

更新日期：2013-11-01 00:00:00

abstract：:We describe here the outcomes of reduced-toxicity alternate-donor stem cell transplant (SCT) with posttransplant cyclophosphamide (PTCy) for primary immunodeficiency disorders (PIDs) in eight children (haploidentical-seven and matched unrelated donor-one). The conditioning was with serotherapy (alemtuzumab-3/rabbit-an...

journal_title：Pediatric blood & cancer

authors： Rastogi N,Katewa S,Thakkar D,Kohli S,Nivargi S,Yadav SP

更新日期：2018-01-01 00:00:00

abstract：:This is the case report of a 14-year young female who was diagnosed with solitary bone plasmacytoma (SBP) of proximal tibia and was treated by local involved field radiotherapy. We present the clinical, radiological and pathological findings of the case and review of the available treatment options and prognosis of th...

journal_title：Pediatric blood & cancer

authors： Kumar P,Sharma SC,Saikia UN,Kumar N,Vyas S,Angurana SL

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Although "aspirin resistance" (AR-inadequate platelet inhibition as suggested by in vitro testing of aspirin-treated patients) has been widely studied in adults and linked to increased risk of adverse outcomes, its prevalence and clinical significance are largely unknown in children. PROCEDURE:To determine ...

journal_title：Pediatric blood & cancer

authors： Yee DL,Dinu BR,Sun CW,Edwards RM,Justino H,Teruya J,Bray PF,Bomgaars L

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Patient transition readiness self-assessment tools and investigation into patient and parent perceptions of the transition process from pediatric to adult care models have informed recognition of gaps in care, particularly for those with chronic disease. Implementation of a longitudinal transition process wi...

journal_title：Pediatric blood & cancer

authors： Croteau SE,Padula M,Quint K,D'Angelo L,Neufeld EJ

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Little is known about the clinical significance of coronary artery dilation (CAD) and left ventricular hypertrophy (LVH) in patients with sickle cell disease (SCD). PROCEDURE:In a retrospective cohort, we studied the prevalence of CAD and LVH in 101 children with SCD in comparison to 93 healthy African-Amer...

journal_title：Pediatric blood & cancer

authors： Johnson MC,Johnikin MJ,Euteneuer JC,DeBaun MR,Hildebolt C

更新日期：2015-01-01 00:00:00

abstract：:Because of increasing survival rates in pediatric oncology, attention is focusing on cancer and its treatment-related side effects. Rehabilitation may reduce their impact. However, the literature does not provide strong evidence regarding rehabilitation pathways. Therefore, the Italian Association of Pediatric Hematol...

journal_title：Pediatric blood & cancer

authors： Rossi F,Ricci F,Botti S,Bertin D,Breggiè S,Casalaz R,Cervo M,Ciullini P,Coppo M,Cornelli A,Esposito M,Ferrarese M,Ghetti M,Longo L,Morri M,Naretto G,Orsini N,Fagioli F,AIEOP Rehabilitation Working Group Members.

更新日期：2020-12-01 00:00:00

abstract：:Poverty is an important patient-reported outcome of therapy and a potential predictor of outcome disparities in pediatric cancer. We previously identified that nearly 30% of pediatric cancer families experience household material hardship (HMH), a concrete measure of poverty including food, energy, or housing insecuri...

journal_title：Pediatric blood & cancer

authors： Bilodeau M,Ma C,Al-Sayegh H,Wolfe J,Bona K

更新日期：2018-01-01 00:00:00

abstract：:Both hepatoblastoma and hypoplastic kidneys are rare in children. A review of all patients with hepatoblastoma treated at our institution between 1993 and 2011 revealed three cases of hepatoblastoma occurring in children with hypoplastic kidneys and significantly impaired renal function. Two patients were treated with...

journal_title：Pediatric blood & cancer

authors： Chan R,Mascarenhas L,Venkatramani R

更新日期：2014-08-01 00:00:00