Non-activated protein C rescue treatment in Wilms tumour associated hepatic sinusoidal obstructive syndrome.

abstract：BACKGROUND:The role of local analgesics for lumbar punctures (LPs) in pediatric oncology patients has not been specifically studied. AIM:To compare the efficacy of eutectic mixture of local anesthetics (EMLA) cream to 1% lidocaine injection for LPs. METHOD:This was a retrospective observational study of all patients ...

journal_title：Pediatric blood & cancer

authors： Cruickshank A,Qeadan F,Kuttesch JF,Agarwal HS

更新日期：2019-11-01 00:00:00

abstract：:Efficacy of therapeutic strategies relative to patient- and family-centered outcomes in pediatric oncology must be assessed. We sought to identify outcomes important to children with acute myeloid leukemia and their families related to inpatient versus at-home management of neutropenia. We conducted qualitative interv...

journal_title：Pediatric blood & cancer

authors： Szymczak JE,Getz KD,Madding R,Fisher B,Raetz E,Hijiya N,Gramatges MM,Henry M,Mian A,Arnold SD,Aftandilian C,Collier AB,Aplenc R

更新日期：2018-04-01 00:00:00

abstract：:Chronic myeloid leukemia (CML) is a rare disease in children. Different from that in adults, childhood CML involves transformative events occurring over a short time period. CML transformation to lymphoid blast phase (BP) is associated with copy number abnormalities, characteristic of BCR-ABL1 positive acute lymphobla...

journal_title：Pediatric blood & cancer

authors： Klumb CE,Barbosa TDC,Nestal de Moraes G,Schramm MT,Emerenciano M,Maia RC

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:This study aimed to compare the health related quality of life (HRQoL) of children and adolescents after malignant bone tumor surgery of the leg with healthy controls. PROCEDURE:Patients between 8 and 25 years old were cross-sectional recruited. Patients under 16 years of age received the TNO (Netherlands O...

journal_title：Pediatric blood & cancer

authors： Bekkering WP,Vliet Vlieland TP,Koopman HM,Schaap GR,Schreuder HW,Beishuizen A,Tissing WJ,Hoogerbrugge PM,Anninga JK,Taminiau AH

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Accurate risk stratification of Langerhans cell histiocytosis (LCH) is essential as management can range from conservative in single system, low risk for central nervous system (CNS) involvement lesions to intensive chemotherapy for multisystem or high-risk disease. Additionally, being able to differentiate ...

journal_title：Pediatric blood & cancer

authors： Ferrell J,Sharp S,Kumar A,Jordan M,Picarsic J,Nelson A

更新日期：2021-01-14 00:00:00

abstract：:Anaphylactic/anaphylactoid reaction to methotrexate (MTX) is uncommon. It may occur with the first dose (non-allergic reactions) or after a previous exposure to the drug (allergic or specific reactions). Desensitization has been shown effective in children with allergic-type reactions permitting the continuation of hi...

journal_title：Pediatric blood & cancer

authors： Oulego-Erroz I,Maneiro-Freire M,Bouzón-Alejandro M,Vázquez-Donsión M,Couselo JM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Using patient-reported outcomes (PROs) in clinical practice has been shown to enhance detection of health-related quality of life problems and satisfaction with care in children with cancer. This study seeks to identify which PRO information healthcare professionals (HCPs) find useful and what the perceived ...

journal_title：Pediatric blood & cancer

authors： Schepers SA,Haverman L,Zadeh S,Grootenhuis MA,Wiener L

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Pain is the most common complication of sickle cell disease requiring emergency department (ED) visits and hospitalization. A Clinical Practice Guideline (CPG) to manage acute sickle cell pain offers clinicians a standardized approach for the provision of evidence-based, cost-effective care. After CPG implem...

journal_title：Pediatric blood & cancer

authors： Morrissey LK,Shea JO,Kalish LA,Weiner DL,Branowicki P,Heeney MM

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:In low- and middle-income countries, therapeutic options for advanced, refractory, or relapsing malignancies are limited due to local constraints such as cost of drugs, distance from oncology centers, and lack of availability of new anticancer drugs. Metronomics, which combines metronomic chemotherapy (MC) a...

journal_title：Pediatric blood & cancer

authors： El Kababri M,Benmiloud S,Cherkaoui S,El Houdzi J,Maani K,Ansari N,Khoubila N,Kili A,El Khorassani M,Madani A,Tazi MA,Ahid S,Hessissen L,Quessar A,Harif M,Khattab M,André N

更新日期：2020-09-01 00:00:00

abstract：:Embryonal rhabdomyosarcoma (ERMS) is the most common childhood sarcoma and is a component of the familial pleuropulmonary blastoma (PPB)-predisposition syndrome. Using the PPB model, we hypothesized that DICER1 mutations would be found in familial and sporadic forms of ERMS. Blood samples from four children with famil...

journal_title：Pediatric blood & cancer

authors： Doros L,Yang J,Dehner L,Rossi CT,Skiver K,Jarzembowski JA,Messinger Y,Schultz KA,Williams G,André N,Hill DA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Severe congenital neutropenia is a rare disease, and autosomal dominantly inherited ELANE mutation is the most frequently observed genetic defect in the registries from North America and Western Europe. However, in eastern countries where consanguineous marriages are common, autosomal recessive forms might b...

journal_title：Pediatric blood & cancer

authors： Yılmaz Karapınar D,Patıroğlu T,Metin A,Çalışkan Ü,Celkan T,Yılmaz B,Karakaş Z,Karapınar TH,Akıncı B,Özkınay F,Onay H,Yeşilipek MA,Akar HH,Tüysüz G,Tokgöz H,Özdemir GN,Aslan Kıykım A,Karaman S,Kılınç Y,Oymak Y,Küpe

更新日期：2019-10-01 00:00:00

abstract：:As a sympathetic nervous system-derived tumor, aggressive neuroblastoma (NB) is currently attracting interest from researchers seeking diagnostic and prognostic markers via less invasive procedures. The analysis of circulating tumor DNA (ctDNA) in peripheral blood can provide genetic information from multiple tumor le...

journal_title：Pediatric blood & cancer

authors： Wei M,Ye M,Dong K,Dong R

更新日期：2020-10-01 00:00:00

abstract：:We report a 10-year-old male with Hb E/Beta thalassemia disease who developed chronic graft-versus-host disease (cGVHD) of antiphospholipid antibody syndrome after successful allogeneic stem cell transplantation (SCT). He exhibited a recurrent ischemic stroke on day 368 post-SCT while on cyclosporine A, azathioprine, ...

journal_title：Pediatric blood & cancer

authors： Sirachainan N,Pakakasama S,Hongeng S,Chuansumrit A,Tuntiyatorn L,Vilaiyuk S

更新日期：2011-07-15 00:00:00

abstract：BACKGROUND:To investigate the incidence, clinical characteristics and survival of malignant tumours of the gastrointestinal tract in children in the West Midlands in Britain over a 44-year span time, to identify any change over this period and to compare the data with the world literature. PROCEDURE:Retrospective popu...

journal_title：Pediatric blood & cancer

authors： Hameed R,Parkes S,Davies P,Morland BJ

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:To determine prognostic factors for local control in the radiotherapeutic management of non-metastatic Ewing sarcoma. PROCEDURE:Forty patients with localized Ewing sarcoma (ES) were treated with primary site RT at one institution. Median RT dose was 55.8 Gy (range, 25.5-76 Gy). Chemotherapy was given to 34 ...

journal_title：Pediatric blood & cancer

authors： Paulino AC,Nguyen TX,Mai WY,Teh BS,Wen BC

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:ABT-751, an orally bioavailable sulfonamide, binds beta-tubulin to inhibit microtubule polymerization. We described response and event-free survival (EFS) in children with neuroblastoma and other solid tumors receiving ABT-751, assessed in vitro cytotoxicity of ABT-751 and evaluated the effect of ABT-751 on ...

journal_title：Pediatric blood & cancer

authors： Meany HJ,Sackett DL,Maris JM,Ward Y,Krivoshik A,Cohn SL,Steinberg SM,Balis FM,Fox E

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Little is known about the effects of chemotherapy on patient antibody titers to vaccine-preventable infectious diseases; thus, there is no standard protocol for revaccinating post-chemotherapy patients. PROCEDURES:To assess losses of detectable antibody titers due to chemotherapy, we retrospectively examine...

journal_title：Pediatric blood & cancer

authors： Yu J,Chou AJ,Lennox A,Kleiman P,Wexler LH,Meyers PA,Gorlick R

更新日期：2007-10-15 00:00:00

abstract：BACKGROUND:Children and adolescents with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) are reported to have increased relapse rates and therapy-related mortality (TRM). Treatment regimens for DS-ALL patients often include therapy modifications. Dana-Farber Cancer Institute (DFCI) ALL Consortium protocols ha...

journal_title：Pediatric blood & cancer

authors： Athale UH,Puligandla M,Stevenson KE,Asselin B,Clavell LA,Cole PD,Kelly KM,Laverdiere C,Leclerc JM,Michon B,Schorin MA,Sulis ML,Welch JJG,Harris MH,Neuberg DS,Sallan SE,Silverman LB

更新日期：2018-10-01 00:00:00

abstract：:As part of a larger effort to create standards for psychosocial care of children with cancer, we document consensus and evidence-based data on interprofessional communication, documentation, and training for professionals providing psycho-oncology services. Six databases were searched. Sixty-five articles and six guid...

journal_title：Pediatric blood & cancer

authors： Patenaude AF,Pelletier W,Bingen K

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The objectives of this study were to determine the maximum tolerated dose (MTD), dose-limiting toxicities (DLTs), pharmacokinetics, and anti-tumor effect of irinotecan in pediatric patients with recurrent or refractory malignancies. PROCEDURE:Twenty-three patients between 1 and 21 years of age, with a solid...

journal_title：Pediatric blood & cancer

authors： Bomgaars L,Kerr J,Berg S,Kuttesch J,Klenke R,Blaney SM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Despite the presence of reports on correlation between major congenital defects and cancer, very few studies have investigated the frequency of minor anomalies in childhood malignancy. The aim of this study was to determine the prevalence of minor anomalies in children with hematological malignancy. PROCEDU...

journal_title：Pediatric blood & cancer

authors： Citak FE,Citak EC,Akkaya E,Kosan B,Ezer U,Kurekci AE

更新日期：2011-02-01 00:00:00

abstract：:Male breast cancer (MBC) is unusual, especially in young adults. Most cases of MBC as a secondary malignancy relate to the previous treatment with ionizing radiation. MBC can be associated with mutations in hereditary cancer predisposition syndrome genes (i.e., BRCA2); however, no such association has been reported in...

journal_title：Pediatric blood & cancer

authors： Hagelstrom RT,Ford J,Reiser GM,Nelson M,Pickering DL,Althof PA,Sanger WG,Coccia PF

更新日期：2016-03-01 00:00:00

abstract：:Sickle cell disease (SCD) is an inherited red blood cell disorder that occurs worldwide and results in significant morbidity and mortality. In addition to affected children who are born in the US, an increasing number of children with SCD are migrating to the US with their families or through international adoption. C...

journal_title：Pediatric blood & cancer

authors： Thornburg CD,Ware RE

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:SIOPEL protocols have recommended liver transplantation for unresectable hepatoblastoma (HBL) after chemotherapy in absence of visible extrahepatic disease. METHODS:This retrospective single center study includes 13 children treated following SIOPEL 3 or 4 protocols who underwent orthotopic liver transplant...

journal_title：Pediatric blood & cancer

authors： Héry G,Franchi-Abella S,Habes D,Brugières L,Martelli H,Fabre M,Pariente D,Gauthier F,Jacquemin E,Branchereau S

更新日期：2011-12-15 00:00:00

abstract：BACKGROUND:Cisplatin (CDDP) ototoxicity is a significant side effect of the current treatment of medulloblastoma (MB). Cumulative dose of CDDP and age are recognized risk factors for hearing loss, but inter-individual susceptibility limits our ability to identify patients at risk for hearing loss. We describe the kinet...

journal_title：Pediatric blood & cancer

authors： Lafay-Cousin L,Purdy E,Huang A,Cushing SL,Papaioannou V,Nettel-Aguirre A,Bouffet E

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Ewing sarcoma of the thoracic spine and chest wall is frequently treated with concurrent chemotherapy and radiation therapy (RT). Treatment-related acute esophagitis can lead to hospitalization and treatment delays. The aim of this study was to analyze the incidence, risk factors, and management of esophagit...

journal_title：Pediatric blood & cancer

authors： Agarwal V,Logie N,Morris CG,Bradley JA,Rotondo RL,Bradfield SM,Indelicato DJ

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Since 1975, childhood cancer incidence rates have gradually increased in the United States; however, few studies have conducted analyses across time to unpack this temporal rise. The aim of this study was to test the hypothesis that increasing cancer incidence rates are due to secular trends in pregnancy cha...

journal_title：Pediatric blood & cancer

authors： Kehm RD,Osypuk TL,Poynter JN,Vock DM,Spector LG

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Severe pandemic influenza A (H1N1) infection can lead to acute respiratory failure (ARF) with associated high mortality. Children with malignancy may be at higher risk of H1N1-associated ARF because of underlying primary disease or immunosuppression associated with chemotherapy. PROCEDURE:We describe the cl...

journal_title：Pediatric blood & cancer

authors： Elbahlawan L,Gaur AH,Furman W,Jeha S,Woods T,Norris A,Morrison RR

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Retinoblastoma occurs in approximately 4 per million children per year in the United States, usually before 2 years of age. In developed countries, 95% of children with tumor in one eye can be cured with enucleation, while children with tumor in both eyes require individualized therapy to preserve vision. Al...

journal_title：Pediatric blood & cancer

authors： Lambert MP,Shields C,Meadows AT

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Extracranial malignant rhabdoid tumor (MRT) is a rare pediatric cancer with a poor prognosis. The kidney is the most common site. Isolated reports have shown improvements in patient survival, but no specific treatment regimen has shown efficacy over others. PROCEDURE:Retrospective review of patients diagnos...

journal_title：Pediatric blood & cancer

authors： Venkatramani R,Shoureshi P,Malvar J,Zhou S,Mascarenhas L

更新日期：2014-08-01 00:00:00