EBV lymphoproliferative disease of host origin after haploidentical stem cell transplantation.

abstract：BACKGROUND:Primary hemophagocytic lymphohistiocytosis (HLH) represents a group of inherited hyperinflammatory immunodeficiencies, including familial HLH (FHL), Griscelli syndrome type 2 (GS2), and X-linked lymphoproliferative syndrome (XLP). We previously reported an annual incidence of suspected primary HLH in Sweden ...

journal_title：Pediatric blood & cancer

authors： Meeths M,Horne A,Sabel M,Bryceson YT,Henter JI

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Cisplatin (CDDP) ototoxicity is a significant side effect of the current treatment of medulloblastoma (MB). Cumulative dose of CDDP and age are recognized risk factors for hearing loss, but inter-individual susceptibility limits our ability to identify patients at risk for hearing loss. We describe the kinet...

journal_title：Pediatric blood & cancer

authors： Lafay-Cousin L,Purdy E,Huang A,Cushing SL,Papaioannou V,Nettel-Aguirre A,Bouffet E

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Wilms tumor is the most common pediatric renal malignancy, but the parameters that are important to its invasion capacity are poorly understood. The aim of this study was to identify new proteins associated with the invasion capacity of Wilms tumor. PROCEDURE:Gene expression profiles for 15 primary Wilms tu...

journal_title：Pediatric blood & cancer

authors： Chetcuti A,Aktas S,Mackie N,Ulger C,Toruner G,Alkan M,Catchpoole D

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:To examine the practical applicability, internal consistency, and validity of the Bt-DUX, a disease-specific Health Related Quality of Life (HRQoL) instrument. The Bt-Dux was developed to examine patients' individual values of their life after a malignant bone tumor of the lower extremity at four domains (co...

journal_title：Pediatric blood & cancer

authors： Bekkering WP,Vlieland TP,Koopman HM,Schaap GR,Schreuder HW,Beishuizen A,Tissing WJ,Hoogerbrugge PM,Anninga JK,Taminiau AH

更新日期：2009-09-01 00:00:00

abstract：:Twenty-eight patients were maintained on subcutaneous immunoglobulin replacement for persistent B-cell aplasia and agammaglobulinemia following CD19-targeted chimeric antigen receptor T-cell therapy for B-cell lymphoblastic leukemia. Patients were transitioned from intravenous to subcutaneous immunoglobulin replacemen...

journal_title：Pediatric blood & cancer

authors： Arnold DE,Maude SL,Callahan CA,DiNofia AM,Grupp SA,Heimall JR

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Irinotecan is highly active against rhabdomyosarcoma (RMS), yet its tolerability and efficacy in combination with radiation is unknown. We examined local control and toxicities in RMS patients treated with radiotherapy (RT) in combination with radiosensitizing agents irinotecan + carboplatin (I + C). PROCED...

journal_title：Pediatric blood & cancer

authors： Dharmarajan KV,Wexler LH,Wolden SL

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To evaluate the association of central nervous system (CNS) treatment intensity and the social functioning of children who have completed treatment for leukemia, lymphoma, and solid tumors outside the CNS. Furthermore, we expected that these associations would be moderated by child age at diagnosis and gender. ...

journal_title：Pediatric blood & cancer

authors： Vannatta K,Gerhardt CA,Wells RJ,Noll RB

更新日期：2007-10-15 00:00:00

abstract：BACKGROUND:We investigated the spectrum, frequency, and risk factors for renal, gastrointestinal, and hepatic late adverse effects in survivors of childhood acute myeloid leukemia (AML) without relapse treated with chemotherapy alone according to three consecutive AML trials by the Nordic Society of Pediatric Hematolog...

journal_title：Pediatric blood & cancer

authors： Skou AS,Glosli H,Jahnukainen K,Jarfelt M,Jónmundsson GK,Malmros-Svennilson J,Nysom K,Hasle H,Nordic Society of Pediatric Hematology and Oncology.

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:A majority of Fanconi anemia (FA) patients will experience bone marrow failure (BMF) and androgen therapy (most often oxymetholone) may be utilized as a treatment to improve BMF-related cytopenias. However, oxymetholone is associated with toxicities making identification of other agents of interest. In this ...

journal_title：Pediatric blood & cancer

authors： Rose SR,Kim MO,Korbee L,Wilson KA,Ris MD,Eyal O,Sherafat-Kazemzadeh R,Bollepalli S,Harris R,Jeng MR,Williams DA,Smith FO

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Over the past decade, PET-CT has been used to assess rhabdomyosarcoma (RMS) in children. However, the role of PET-CT in staging RMS is unknown. PROCEDURE:Thirty subjects with RMS, median age 7.3 years, underwent PET-CT before therapy. PET-CTs and conventional imaging (CI) were independently reviewed by two ...

journal_title：Pediatric blood & cancer

authors： Federico SM,Spunt SL,Krasin MJ,Billup CA,Wu J,Shulkin B,Mandell G,McCarville MB

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Children with sickle cell disease (SCD) are at increased risk of death from invasive bacterial infections. Emergent evaluation of fever allows early treatment of potentially fatal infections. Limited data exist regarding caregiver adherence to physician recommendations of prompt medical evaluation of fever i...

journal_title：Pediatric blood & cancer

authors： Schultz CL,Tchume-Johnson T,Schapira MM,Bellamy S,Smith-Whitley K,Ellison A

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Positron emission tomography (PET) and gallium scans facilitate diagnosis and staging, evaluation of response to therapy, and monitoring for relapse in Hodgkin lymphoma (HL), but have not been compared in pediatric HL. PROCEDURE:We performed concurrent PET and gallium scans on 44 pediatric HL patients at di...

journal_title：Pediatric blood & cancer

authors： Hines-Thomas M,Kaste SC,Hudson MM,Howard SC,Liu WA,Wu J,Kun LE,Shulkin BL,Krasin MJ,Metzger ML

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The introduction of the United Kingdom Medical Research Council's 10th AML trial (MRC AML 10) protocol incorporating high-dose anthracycline therapy has improved outcome of children with acute myeloid leukemia (AML). In this study, we review the results of childhood AML therapy in a Singapore university hosp...

journal_title：Pediatric blood & cancer

authors： Tan RM,Quah TC,Aung L,Liang S,Kirk RC,Yeoh AE

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Complications in pediatric cancer patients after a gastrostomy (GT) placement have not been widely investigated. We aimed to evaluate the complication rate and nature of complications in this specific population. PROCEDURE:Medical records of pediatric cancer patients having a GT placed at our institution fr...

journal_title：Pediatric blood & cancer

authors： Fernandez-Pineda I,Sandoval JA,Jones RM,Boateng N,Wu J,Rao BN,Davidoff AM,Shochat SJ

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Sickle cell disease (SCD) is an inherited blood disorder characterized by a chronic hemolytic anemia that can contribute to fatigue and global cognitive impairment in patients. The study objective was to report on the feasibility, reliability, and validity of the PedsQL™ Multidimensional Fatigue Scale in SCD...

journal_title：Pediatric blood & cancer

authors： Panepinto JA,Torres S,Bendo CB,McCavit TL,Dinu B,Sherman-Bien S,Bemrich-Stolz C,Varni JW

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Childhood germ cell tumors (cGCTs), believed to arise from transformed primordial germ cells by an unknown mechanism, provide a unique model system for investigating cell signaling, pluripotency, and the microenvironment of neoplastic stem cells (NSCs) in vivo. This is the first report of proteomics of cGCTs...

journal_title：Pediatric blood & cancer

authors： Haskins WE,Eedala S,Jadhav YL,Labhan MS,Pericherla VC,Perlman EJ

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:A National Thalassemia Screening Program was adopted in Taiwan in 1993. This report examined that program's results and impact. METHODS:Patients with beta-thalassemia major born between 1994 and 2003 were recruited through the help of all thalassemia clinics in Taiwan. A structured questionnaire was designed...

journal_title：Pediatric blood & cancer

authors： Chern JP,Lin KH,Lu MY,Lin DT,Jou ST,Yang YL,Chang HH,Su S,Lin KS

更新日期：2008-01-01 00:00:00

abstract：:Congenital hypotransferrinemia (OMIM 209300) is an extremely rare disorder of inherited iron metabolism. Since its description in 1961, only 16 cases have been reported. The defective gene and molecular defect causing this disorder and clinicolaboratory findings seen in the homozygous and heterozygous states have been...

journal_title：Pediatric blood & cancer

authors： Aslan D

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The neurokinin-1 receptor antagonist aprepitant, plus a 5HT3 antagonist and corticosteroid is well-tolerated and effective in preventing chemotherapy-induced nausea and vomiting in adults but has not been formally assessed in adolescents. PROCEDURE:Patients age 11-19 years old receiving emetogenic chemother...

journal_title：Pediatric blood & cancer

authors： Gore L,Chawla S,Petrilli A,Hemenway M,Schissel D,Chua V,Carides AD,Taylor A,Devandry S,Valentine J,Evans JK,Oxenius B,Adolescent Aprepitant in Cancer Study Group.

更新日期：2009-02-01 00:00:00

abstract：:It is unclear if dosing intervals for Erwinase can be extended with intramuscular (i.m.) versus intravenous (i.v.) dosing. Children with acute lymphoblastic leukemia received Erwinase at 30 000-42 000 IU/m2 i.v. or i.m. I.m. Erwinase (n = 22) achieved activity above 0.1 IU/mL for longer than i.v. Erwinase (n = 33) (3....

journal_title：Pediatric blood & cancer

authors： Panetta JC,Liu Y,Swanson HD,Karol SE,Pui CH,Inaba H,Jeha S,Relling MV

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Fever in neutropenic (FN) patients requires immediate broad-spectrum antibiotics, however, such patients do not represent a homogeneous population and the majority of them are at low risk of developing complication. Gatifloxacin (GA) is an alternative, though it has not been thoroughly studied in Pediatrics ...

journal_title：Pediatric blood & cancer

authors： Petrilli A,Altruda Carlesse F,Alberto Pires Pereira C

更新日期：2007-10-15 00:00:00

abstract：BACKGROUND:Testicular germ cell tumors (T-GCTs) occur from infancy to adulthood, and are the most common solid tumor in adolescent and young adult males. Traditionally, pediatric T-GCTs were perceived as more indolent than adult T-GCTs. However, there are few studies comparing these groups and none that specifically ev...

journal_title：Pediatric blood & cancer

authors： Cost NG,Lubahn JD,Adibi M,Romman A,Wickiser JE,Raj GV,Sagalowsky AI,Margulis V

更新日期：2014-03-01 00:00:00

abstract：:Hospital-based home care (HBHC) is widely applied in Pediatric Oncology. We reviewed the potential effect of HBHC on children's physical health and risk of adverse events, parental and child satisfaction, quality of life of children and their parents, and costs. A search of PubMed, CINAHL, and EMBASE led to identifica...

journal_title：Pediatric blood & cancer

authors： Hansson H,Hallström I,Kjaergaard H,Johansen C,Schmiegelow K

更新日期：2011-09-01 00:00:00

abstract：:We present here a case of MIRAGE syndrome due to novel variant (c.2318T>C) in the sterile α motif domain-containing protein 9 (SAMD9) gene. Previous reports have described the clinical phenotype, which includes myelodysplasia, recurrent infections, restriction of growth and development, adrenal insufficiency, genitour...

journal_title：Pediatric blood & cancer

authors： Perisa MP,Rose MJ,Varga E,Kamboj MK,Spencer JD,Bajwa RPS

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:NWTS-5 was a multi-institutional clinical trial for patients less than 16 years of age at diagnosis with specific renal neoplasms who were diagnosed between August 1, 1995 and May 31, 2002. A uniform approach to the treatment of patients with relapse was employed. PATIENTS AND METHODS:Seventy-two patients who ...

journal_title：Pediatric blood & cancer

authors： Green DM,Cotton CA,Malogolowkin M,Breslow NE,Perlman E,Miser J,Ritchey ML,Thomas PR,Grundy PE,D'Angio GJ,Beckwith JB,Shamberger RC,Haase GM,Donaldson M,Weetman R,Coppes MJ,Shearer P,Coccia P,Kletzel M,Macklis R,To

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Although maternal thrombocytopenia during pregnancy is common, its effect on neonatal platelets has not yet been fully evaluated. METHODS:We retrospectively evaluated the rate of thrombocytopenia among 767 healthy term neonates (gestational age 37-42 weeks) born to 723 mothers with pregnancy-induced thrombo...

journal_title：Pediatric blood & cancer

authors： Maayan-Metzger A,Leibovitch L,Schushan-Eisen I,Strauss T,Kenet G,Kuint J

更新日期：2010-07-15 00:00:00

abstract：BACKGROUND:The views and clinical practice of children's cancer units were surveyed regarding management of central venous catheter (CVC) occlusion (CVC-occlusion), CVC-related thrombosis (CVC-thrombosis) and thromboembolism (CVC-thromboembolism). PROCEDURE:A questionnaire was sent to all 22 United Kingdom Children's ...

journal_title：Pediatric blood & cancer

authors： Skinner R,Koller K,McIntosh N,McCarthy A,Pizer B,United Kingdom Children's Cancer Study Group (UKCCSG).,Paediatric Oncology Nursing Forum (PONF) Supportive Care Group.

更新日期：2008-04-01 00:00:00

abstract：:Ameloblastic fibro-odontosarcoma (AFOS) is an extremely rare malignant odontogenic tumor. Complete surgical excision is the treatment of choice. Deaths due to disease recurrence and/or progression are documented. Here, we report the case of a 15-year-old female with multiple recurrent AFOS. She responded to chemothera...

journal_title：Pediatric blood & cancer

authors： Gatz SA,Thway K,Mandeville H,Kerawala C,MacVicar D,Chisholm J

更新日期：2015-11-01 00:00:00

abstract：:Opsoclonus, myoclonus, ataxia syndrome (OMA) is a severe neurologic disorder often associated with neuroblastoma. It is challenging to treat and can have long-term neurologic sequelae. Current recommended therapies include intravenous immunoglobulin, corticosteroids, rituximab, and chemotherapy (cyclophosphamide). We ...

journal_title：Pediatric blood & cancer

authors： Johnston DL,Murray S,Irwin MS,Doyle J,Schechter T

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Malignant ectomesenchymoma (MEM) is a soft tissue tumor with heterologous rhabdomyoblastic components believed to arise from pluripotent migratory neural crest cells. To date merely 50 cases have been published and the knowledge about the course of disease and optimal treatment is limited. METHODS:Six patie...

journal_title：Pediatric blood & cancer

authors： Dantonello TM,Leuschner I,Vokuhl C,Gfroerer S,Schuck A,Kube S,Nathrath M,Bernbeck B,Kaatsch P,Pal N,Ljungman G,Bielack SS,Klingebiel T,Koscielniak E,CWS.

更新日期：2013-02-01 00:00:00