Abstract：
:Background There is a lack of data on the prevalence of potentially inappropriate medications (PIMs) in community-dwelling older adults in China. Objective To assess the prevalence of potentially inappropriate medication in community dwelling older adults in China and to investigate risk factors associated with the use of such medication. Setting Ambulatory Care Clinic of Xiangya Hospital, Central South University. Method A cross-sectional retrospective review of prescriptions for older patients (aged ≥ 65 years) was performed using the 2019 American Geriatrics Society (AGS) Beers Criteria and the 2017 Chinese Criteria. We only assessed potentialli inappropriate medications independently from diagnosis and drug-drug interactions. Each patient was classified as PIM-user or non-PIM-user, according to whether a patient took at least one potentially inappropriate medication. Main outcome measure Prevalence of potentially inappropriate medication based on the two criteria. Results A total of 8477 medications among 1874 elderly patients were examined over the study period from January 1 to December 31, 2018. The Chinese Criteria detected significantly more PIM-users than the AGS Beers Criteria (50.6% vs 35.0%, P < 0.001), and also a higher percentage of inappropriate medication in prescribed medications (14.7% vs 8.5%, P < 0.001). Benzodiazepines, anticholinergics, antipsychotics, and insulin were the most frequently prescribed classes by both criteria. Alprazolam (47.7%) was the most frequently found inappropriate medicine based on the 2019 AGS Beers Criteria compared to clopidogrel (42.2%) based on the Chinese Criteria. The number of medications was a significant risk factor to the use of potentially inappropriate medication in both criteria. Conclusion The prevalence of the use of potentially inappropriate medication in Chinese community-dwelling older adults is high, and explicit criteria are a useful tool to evaluate the prescription of such medication in the elderly.
journal_name
Int J Clin Pharmjournal_title
International journal of clinical pharmacyauthors
Huang Y,Zhang L,Huang X,Liu K,Yu Y,Xiao Jdoi
10.1007/s11096-020-00980-ysubject
Has Abstractpub_date
2020-04-01 00:00:00pages
598-603issue
2eissn
2210-7703issn
2210-7711pii
10.1007/s11096-020-00980-yjournal_volume
42pub_type
杂志文章abstract：:Background The efficacy and safety of direct oral anticoagulants is well established in patients with atrial fibrillation. However, data on their use in the oldest old patients (≥ 85 years), who have the highest risk of bleeding, is scarce. Objective The aim of this study was to evaluate the safety of direct oral anti...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01008-1
更新日期：2020-04-01 00:00:00
abstract：:Background Coeliac disease affects 1% of the population, but 75% remain undiagnosed. Objective To conduct a case finding feasibility and efficacy study for the detection of coeliac disease in community pharmacies. Setting Six community pharmacies across Sheffield, UK. Method A prospective study was performed using a p...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-019-00793-8
更新日期：2019-04-01 00:00:00
abstract：:Background Adherence to oral antidiabetics plays a pivotal role in controlling diabetes. Healthcare workers evaluate this adherence when visited by patients. Objectives The primary objective of this study was to validate the existing LMAS-14 (Lebanese Medication Adherence Scale) in Lebanese diabetic adults. The second...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01197-9
更新日期：2020-11-17 00:00:00
abstract：:BackgroundAccess to drugs with hospital-restricted dispensation, such as those for patients with rheumatoid arthritis or psoriasis, is regulated by healthcare policy. These drugs have the greatest cost-effective impact on the healthcare system. This is why a model for Pharmaceutical Care based on follow-up teleconsult...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01200-3
更新日期：2020-11-23 00:00:00
abstract：OBJECTIVE:To generate, validate and establish a web-based individualised opioid conversion calculator at the University Hospital Basel and to analyse its value and significance. SETTING:A 700-bed university hospital. METHOD:Published data were screened by a Medline search using the keywords: opioid, rotation, switchi...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-010-9464-z
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Patients with advanced cancers are at high risk for bone metastases, which accelerate bone resorption and skeletal complications. Therefore, bisphosphonates, which are strong inhibitors of bone resorption, are widely used to prevent pathological fractures, pain and tumour-induced hypercalcaemia. Intravenous ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9994-x
更新日期：2014-12-01 00:00:00
abstract：:Background Chronic pain is a prevalent and debilitating condition for many people. Globally it is the greatest contributor to years lived with disability. Management often includes pharmacotherapy and pharmacists are therefore well placed to contribute to chronic pain management. Objective To explore chronic pain mana...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01198-8
更新日期：2020-11-27 00:00:00
abstract：BACKGROUND:Zoledronic acid (ZA) is an intravenous bisphosphonate approved for the prevention and treatment of cancer skeletal-related events. OBJECTIVE:Our aim was to analyze the prescription patterns of ZA in the cancer outpatient clinic. METHOD:We performed a retrospective chart review of all patients who received ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9693-4
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:The prevalence of diabetes in Jordan is among the highest in the world, making it a particularly alarming health problem there. It has been indicated that poor adherence to the prescribed therapy lead to poor glycemic control and enhance the development of diabetes complications and unnecessary hospitalizati...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9938-5
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:Improper disposal of medications potentially poses a significant environmental risk and storage of expired and unused medications in households provides an increased risk of accidental childhood poisonings. OBJECTIVE:The objective of this study was to investigate the storage and disposal habits of medicatio...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9652-0
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Research conducted in Jordan has shown that suboptimal use of medications by outpatients along with the suboptimal role played by community pharmacists is currently a big dilemma highlighting the need for the Home Medication Review (HMR) service in the country. OBJECTIVES:To evaluate the prevalence and type...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9713-4
更新日期：2013-02-01 00:00:00
abstract：CASE:We report a 32-year old relapse case of Visceral leishmaniasis, treated with Paromomycin who belonged from a endemic zone of Bihar state, India. After confirmation, he was treated with Amphotericin B, followed by Liposomal Amphotericin B in full course and even in higher dose. But after each therapy, the patient e...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-011-9544-8
更新日期：2011-10-01 00:00:00
abstract：:Background Half of Americans experience mental illness during their lifetime. Significant opportunity exists for community pharmacists to deliver services to these patients; however, personal and practice-related barriers may prevent full engagement. Objective To assess the demographics, practice characteristics, serv...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-018-0619-7
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Communication between hospital and community pharmacists when a patient is discharged from hospital can improve the accuracy of medication reconciliation, thus preventing unintentional changes and ensuring continuity of supply. It allows problems to be resolved before a patient requires a further supply of m...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-013-9813-9
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVE:A major UK Pharmacy chain private Chlamydia screening and treatment service began in October 2006. People pay for a screening kit, send off a urine sample, and are informed of their result directly. Treatment is accessed via the pharmacy chain or the National Health Service. We analysed data from the first 2 ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-010-9460-3
更新日期：2011-02-01 00:00:00
abstract：:Background Medication dispensing is a core function of community pharmacies, and errors that occur during the dispensing process are a major concern for pharmacy profession. However, to date there has been no national study of medication dispensing errors in Jordan. Objective The study aimed to investigate the inciden...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01126-w
更新日期：2020-08-17 00:00:00
abstract：: ...
journal_title：International journal of clinical pharmacy
pub_type：
doi：10.1007/s11096-018-0759-9
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Patients with type 2 diabetes mellitus (T2DM) are frequently admitted to the hospital with severe or acute hyperglycaemia secondary to an acute illness or disease. Uncontrolled glycaemia is a significant problem during severe or acute hyperglycaemia. OBJECTIVE:This study sought to identify demographic, clin...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9682-7
更新日期：2012-12-01 00:00:00
abstract：:Background Valproate is a widely prescribed antiepileptic drug for generalized epilepsies, due to the extensive knowledge on its efficacy since it is on the market for many decades. However, a large number of new antiepileptic medicines was introduced into clinical practice and may be better options for treatment, con...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章,meta分析
doi：10.1007/s11096-018-0641-9
更新日期：2018-06-01 00:00:00
abstract：:Setting Fifteen community pharmacies in the UK. Objective Proof of concept study to test the use of community pharmacies for active case finding of patients with coeliac disease. Methods Customers accessing over-the counter and prescription medicines indicated in the treatment of possible symptoms of coeliac disease o...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0368-4
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:Evidence suggests that consumers potentially put themselves at risk when purchasing medicines on-line. Whilst logos provided by regulators may provide some level of reassurance there may be other indicators which could be used by consumers to identify those websites which may be safely used. OBJECTIVES:Iden...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-0056-1
更新日期：2015-02-01 00:00:00
abstract：CASE DESCRIPTION:Hyperkalemia can cause altered cardiac electrical conduction resulting in death. We describe a case of a 23-year old pregnant patient who presented with severe epigastric pain and vomiting. She was severely pre- eclamptic and received initial treatment with intravenous labetalol and decision was taken ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-0021-z
更新日期：2014-12-01 00:00:00
abstract：:Background Pharmacist-physician collaboration can lead to many positive outcomes. However, collaboration between healthcare providers is complex and rarely performed optimally. Objectives To study physician-pharmacist collaboration in hospital settings, from the physician's point of view. Setting Eight regional non-te...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0395-1
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Oral treatment in women with breast cancer has been increasingly used. However, a potentially negative side of oral medication is poor patient adherence and/or discontinuation, which reduces the treatment effectiveness, accelerating progression of the disease and reducing the patient survival rate. AIM OF T...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11096-013-9833-5
更新日期：2014-02-01 00:00:00
abstract：:Background Atrial fibrillation (AF) is a risk factor for stroke in older people. Oral anticoagulants can reduce stroke risk but they are commonly under prescribed in the elderly, often due to concerns regarding the risk of bleeding. Prescribing in aged care residents may also be further complicated by associated geria...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01025-0
更新日期：2020-04-01 00:00:00
abstract：:Background Modern antiviral treatments have high cure rates against the hepatitis C virus however, the high cost associated with branded medicines and diagnostic tests, have resulted in poor access for many low-income patients residing in low-and-middle-income countries. Objective This study aimed to evaluate the role...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01202-1
更新日期：2020-11-28 00:00:00
abstract：:Background Taking regular medication has been shown to have an impact on the daily lives of patients and their families. Objective To explore the medication-related experiences of patients and their families when a child or young person is prescribed regular medication. Setting A specialist U.K. paediatric hospital. M...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-018-0756-z
更新日期：2019-02-01 00:00:00
abstract：:Background Little is known about the extent of drug-related problems (DRPs) in community-dwelling older adult patients with chronic diseases in mainland China. Setting A medication therapy review service at a community health center in Chongqing, China. Objective To identify and categorize DRPs along with pharmacists'...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-017-0587-3
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVES:Diabetes mellitus is a chronic progressive disease characterized by numerous health complications. Medication adherence is an important determinant of therapeutic outcome. Few studies on medication adherence have been published from the Arab countries. Therefore, the objective of this pilot study was to asse...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-011-9561-7
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:A range of extended/enhanced pharmacy services (EPS) are increasingly being offered in community pharmacies following a global paradigm shift in professional pharmacy practice from a product-oriented focus to a patient-centered approach. A number of pharmacy/pharmacist characteristics have been reported to i...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-015-0127-y
更新日期：2015-10-01 00:00:00
