Abstract：
:Background Coeliac disease affects 1% of the population, but 75% remain undiagnosed. Objective To conduct a case finding feasibility and efficacy study for the detection of coeliac disease in community pharmacies. Setting Six community pharmacies across Sheffield, UK. Method A prospective study was performed using a point of care test, Simtomax® (IgA/IgG-deamidated gliadin peptide) (C-test) in pharmacies. Pharmacy customers with symptoms suggestive of or risk factors for coeliac disease were tested with the C-test. Positive individuals were referred for a gastroscopy with duodenal biopsies alongside conventional serology. People with known coeliac disease, those on a gluten free diet or those who were investigated for coeliac disease were excluded. Main outcome measure The case detection rate and the uptake rate of the C-test and gastroscopies. Results Five-hundred participants fulfilled the inclusion criteria and were tested with the C-test (369 females, 73.8%; age range 18-87, median 49). The C-test uptake rate was 63%, and the positive rate was 7.2% (36/500). Twenty-seven positive participants (75%) underwent further investigations, confirming three new cases of coeliac disease (0.6%). Conclusion It was feasible to use the C-test as a case finding tool in pharmacies. There was good uptake for the C-test, although the case detection rate and the test specificity were low. Based on this, the C-test has a limited role in case finding in a community pharmacy setting.
journal_name
Int J Clin Pharmjournal_title
International journal of clinical pharmacyauthors
Lau MS,Sanders DSdoi
10.1007/s11096-019-00793-8subject
Has Abstractpub_date
2019-04-01 00:00:00pages
583-588issue
2eissn
2210-7703issn
2210-7711pii
10.1007/s11096-019-00793-8journal_volume
41pub_type
杂志文章abstract：OBJECTIVE:To evaluate the effects of pharmacotherapy follow-up (PF) on metabolic control and clinical outcomes in type 2 diabetic patients. SETTING:Six community pharmacies (4 intervention and 2 control) in the Curitiba metropolitan region (Brazil). MAIN OUTCOME MEASURE:Glycosylated Haemoglobin A1 (HbA1) and fasting ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-011-9493-2
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:To generate, validate and establish a web-based individualised opioid conversion calculator at the University Hospital Basel and to analyse its value and significance. SETTING:A 700-bed university hospital. METHOD:Published data were screened by a Medline search using the keywords: opioid, rotation, switchi...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-010-9464-z
更新日期：2011-02-01 00:00:00
abstract：:Background There are two fundamental approaches to clinical reasoning, intuitive and analytical. These approaches have yet to be well explored to describe how pharmacists make decisions to determine medication appropriateness. Objective (1) to identify the cognitive actions (i.e., operators) that pharmacists employ wh...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-019-00906-3
更新日期：2019-12-01 00:00:00
abstract：:Background Rheumatoid arthritis is a chronic, autoimmune disease in which treatment has evolved with a variety of therapeutic classes. Biological disease-modifying antirheumatic drugs have improved therapy; however, the continued long-term use of these drugs with sustained safety and efficacy remains a challenge. Obje...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01171-5
更新日期：2020-10-21 00:00:00
abstract：BACKGROUND:There can be a lack of transfer of information between hospitals and community pharmacies following patient discharge, which puts patients at a high risk of suffering drug related problems (DRPs). Community pharmacy plays a vital role in identifying and solving these discharge DRPs and taking action before t...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9935-8
更新日期：2014-06-01 00:00:00
abstract：:Background Patients admitted to intensive care unit (ICU) present with severe and life-threatening illnesses. Most of them suffer from various comorbidities. They usually receive complex pharmacotherapy with large number of medicines which increase the risk of drug-drug interactions (DDIs). Objective The present repor...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0340-3
更新日期：2016-10-01 00:00:00
abstract：:Background Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used pharmaceutical agents worldwide. NSAIDs are considered nephrotoxic and should therefore be used with caution or be avoided completely in high risk patients, such as chronic kidney disease (CKD) patients. Objective This study aim...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0298-1
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Improper disposal of medications potentially poses a significant environmental risk and storage of expired and unused medications in households provides an increased risk of accidental childhood poisonings. OBJECTIVE:The objective of this study was to investigate the storage and disposal habits of medicatio...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9652-0
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Patients with advanced cancers are at high risk for bone metastases, which accelerate bone resorption and skeletal complications. Therefore, bisphosphonates, which are strong inhibitors of bone resorption, are widely used to prevent pathological fractures, pain and tumour-induced hypercalcaemia. Intravenous ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9994-x
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:A range of extended/enhanced pharmacy services (EPS) are increasingly being offered in community pharmacies following a global paradigm shift in professional pharmacy practice from a product-oriented focus to a patient-centered approach. A number of pharmacy/pharmacist characteristics have been reported to i...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-015-0127-y
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Renal abnormalities are often seen in sickle cell disease (SCD). OBJECTIVE:To investigate the role of hydroxycarbamide as a protective agent in sickle cell nephropathy. SETTING:Patients with SCD followed at a Hematology outpatients clinic. METHODS:Prospective study with 26 SCD patients. Renal function eva...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9955-4
更新日期：2014-08-01 00:00:00
abstract：:It is widely acknowledged that patients-particularly those late in life-are frequently exposed to the harms of medication. To minimize these harms, several frameworks have been developed by which prescribing can be optimized. In the context of diminishing life expectancy, these frameworks can be used to reduce medicat...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-015-0148-6
更新日期：2015-10-01 00:00:00
abstract：:Bridging the gap between hospital and primary care is important as transition from one healthcare setting to another increases the risk on drug-related problems and consequent readmissions. To reduce those risks, pharmacist interventions during and after hospitalization have been frequently studied, albeit with variab...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-015-0093-4
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:For patients accessing specialist palliative care day services, medication is prescribed routinely to manage acute symptoms, treat long-term conditions or prevent adverse events associated with these conditions. As such, the pharmacotherapeutic burden for these patients is high and polypharmacy is common. Co...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9932-y
更新日期：2014-06-01 00:00:00
abstract：:Background Misuse of prescription medicines is a global issue potentially resulting in severe consequences including adverse drug reactions, dependence, tolerance, increased healthcare utility and mortality. Objective To assess the public's perspectives of issues relating to medicines misuse. Method A survey of member...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-019-00893-5
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:In September 2007, the FDA issued an alert recommending that ceftriaxone and calcium-containing solutions should not be administered to any patient within 48 h of each other. Due to the widespread use of ceftriaxone, significant concern was expressed by the greater healthcare community about the warning, whic...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-011-9503-4
更新日期：2011-06-01 00:00:00
abstract：:Background Modern antiviral treatments have high cure rates against the hepatitis C virus however, the high cost associated with branded medicines and diagnostic tests, have resulted in poor access for many low-income patients residing in low-and-middle-income countries. Objective This study aimed to evaluate the role...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01202-1
更新日期：2020-11-28 00:00:00
abstract：BACKGROUND:Medication errors are a potential major threat to patient's health, and allergic reactions occurring in patients with known allergies are an important preventable form of adverse drug event. The use of penicillin antibiotics in patients who are allergic to penicillin, in particular, is a major concern. AIM:...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9708-1
更新日期：2013-02-01 00:00:00
abstract：:Background While dispensing prescribed medicines, pharmacists frequently encounter technical and clinical problems that require a pharmaceutical intervention. Objective To describe the pharmaceutical interventions performed by community pharmacists while dispensing prescribed medicines and to investigate, in-depth, th...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-018-0595-y
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Smoking cessation represents one of the best means of preventing smoking-related complications. In recent years, a majority of hospitals have implemented smoke-free policies, making support for smoker patients a necessary and indispensable task. The clinical pharmacist is well-positioned to provide this kind...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9927-8
更新日期：2014-06-01 00:00:00
abstract：:Medications are perceived as health risk factors, because they might cause damage if used improperly. In this context, an adequate assessment of medication use history should be encouraged, especially in transitions of care to avoid unintended medication discrepancies (UMDs). In a case-controlled study, we investigate...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章,评审
doi：10.1007/s11096-017-0519-2
更新日期：2017-10-01 00:00:00
abstract：:Background The treatment of heart failure patients is very complex and includes lifestyle modification as well as different pharmacological therapies. Polypharmacy is very common in such patients and they are at increased risk of potential drug-drug interactions and associated effects such as poor adherence, complianc...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-019-00918-z
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:The combined post-operative use of diuretics and/or renin-angiotensin-aldosterone system (RAAS) inhibitors may increase the risk of nonsteroidal anti-inflammatory drug (NSAID) associated renal failure because of a drug-drug interaction. OBJECTIVE:The aim of this study was to investigate the effect of the sh...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9631-5
更新日期：2012-06-01 00:00:00
abstract：:Background Atrial fibrillation (AF) is a risk factor for stroke in older people. Oral anticoagulants can reduce stroke risk but they are commonly under prescribed in the elderly, often due to concerns regarding the risk of bleeding. Prescribing in aged care residents may also be further complicated by associated geria...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01025-0
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Patient satisfaction is an important determinant of the feasibility and sustainability of community pharmacy screening services. However, few studies have evaluated this, with no such study performed for a chronic kidney disease risk assessment service. OBJECTIVE:The aim was to determine patient satisfactio...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-018-0603-2
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Generic uptake will increasingly be promoted by governments in the face of increasing healthcare costs and global economic uncertainties. OBJECTIVE:The purpose of this study was to investigate attitudes towards generic substitution among community pharmacists, with a focus on the perception of the efficacy,...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-015-0227-8
更新日期：2016-02-01 00:00:00
abstract：:Background The Middle East region has one the highest prevalence rates of diabetes in the world. Little is known about the determinants of adherence and the role of knowledge in diabetes self-management within these populations. Objective To investigate the relationship between patients knowledge of diabetes therapeut...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章,多中心研究
doi：10.1007/s11096-016-0375-5
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Both clinical pharmacists and computerized physician order entry systems with clinical decision support (CPOE/CDSS) can reduce drug-related problems (DRPs). However, the contribution of a clinical pharmacist in addition to CPOE/CDSS has not been established in a prospective study. OBJECTIVE:To determine whi...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-013-9798-4
更新日期：2013-10-01 00:00:00
abstract：:Background Medication errors are the most common types of medical errors that occur in health care organisations; however, these errors are largely underreported. Objective This study assessed knowledge on medication error reporting, perceived barriers to reporting medication errors, motivations for reporting medicati...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01041-0
更新日期：2020-08-01 00:00:00
abstract：:Background The New Medicines Service (NMS) was implemented in the United Kingdom in 2011 and first evaluated in 2014, showing 10% increase on adherence. Objective To assess community pharmacists' current practice, knowledge and confidence in supporting patients' adherence as part of the NMS for patients on Oral Anti-C...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-017-0529-0
更新日期：2017-12-01 00:00:00
