Abstract：
CASE:We report a 32-year old relapse case of Visceral leishmaniasis, treated with Paromomycin who belonged from a endemic zone of Bihar state, India. After confirmation, he was treated with Amphotericin B, followed by Liposomal Amphotericin B in full course and even in higher dose. But after each therapy, the patient either did not responded or relapsed after treatment. Ultimately, the patient was successfully treated with combination therapy of Liposomal amphotericin B and Miltefosine without any relapse. CONCLUSION:The multi-drug unresponsive Visceral leishmaniasis cases could pose a major threat to treatment strategy in the elimination program. In such situation, combination therapy seems to be a better approach that needs to be explored.
journal_name
Int J Clin Pharmjournal_title
International journal of clinical pharmacyauthors
Kumar N,Sinha PK,Pandey K,Verma N,Lal CS,Ranjan A,Verma RB,Das Pdoi
10.1007/s11096-011-9544-8subject
Has Abstractpub_date
2011-10-01 00:00:00pages
726-9issue
5eissn
2210-7703issn
2210-7711journal_volume
33pub_type
杂志文章abstract：:Background The efficacy and safety of direct oral anticoagulants is well established in patients with atrial fibrillation. However, data on their use in the oldest old patients (≥ 85 years), who have the highest risk of bleeding, is scarce. Objective The aim of this study was to evaluate the safety of direct oral anti...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01008-1
更新日期：2020-04-01 00:00:00
abstract：:Background Half of Americans experience mental illness during their lifetime. Significant opportunity exists for community pharmacists to deliver services to these patients; however, personal and practice-related barriers may prevent full engagement. Objective To assess the demographics, practice characteristics, serv...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-018-0619-7
更新日期：2018-10-01 00:00:00
abstract：:Background Patient centred communication can improve pharmaceutical care, but is not well described for pharmacists. Aim of the review To provide a comprehensive and accessible overview of the concept of patient centred communication for the pharmacy practice. Method A scoping review and thematic analysis was undertak...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章,评审
doi：10.1007/s11096-017-0508-5
更新日期：2017-12-01 00:00:00
abstract：:Background The treatment of heart failure patients is very complex and includes lifestyle modification as well as different pharmacological therapies. Polypharmacy is very common in such patients and they are at increased risk of potential drug-drug interactions and associated effects such as poor adherence, complianc...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-019-00918-z
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVES:Diabetes mellitus is a chronic progressive disease characterized by numerous health complications. Medication adherence is an important determinant of therapeutic outcome. Few studies on medication adherence have been published from the Arab countries. Therefore, the objective of this pilot study was to asse...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-011-9561-7
更新日期：2011-12-01 00:00:00
abstract：:Setting Fifteen community pharmacies in the UK. Objective Proof of concept study to test the use of community pharmacies for active case finding of patients with coeliac disease. Methods Customers accessing over-the counter and prescription medicines indicated in the treatment of possible symptoms of coeliac disease o...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0368-4
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:The variability in the clinical response to clopidogrel treatment has been attributed to genetic factors, but the specific genes and other risk factors remain unclear. OBJECTIVE:To investigate the incidence of high on-treatment platelet reactivity in coronary heart disease patients following clopidogrel the...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-019-00953-w
更新日期：2020-02-01 00:00:00
abstract：UNLABELLED:Background Controversy about the introduction of a non-dispensing pharmacist in primary care practice hampers implementation. Objective The aim of this study is to systematically map the debate on this new role for pharmacists amongst all stakeholders to uncover and understand the controversy and consensus. ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0360-z
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:Patients with advanced cancers are at high risk for bone metastases, which accelerate bone resorption and skeletal complications. Therefore, bisphosphonates, which are strong inhibitors of bone resorption, are widely used to prevent pathological fractures, pain and tumour-induced hypercalcaemia. Intravenous ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9994-x
更新日期：2014-12-01 00:00:00
abstract：:Background The New Medicines Service (NMS) was implemented in the United Kingdom in 2011 and first evaluated in 2014, showing 10% increase on adherence. Objective To assess community pharmacists' current practice, knowledge and confidence in supporting patients' adherence as part of the NMS for patients on Oral Anti-C...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-017-0529-0
更新日期：2017-12-01 00:00:00
abstract：:Background Patients admitted to intensive care unit (ICU) present with severe and life-threatening illnesses. Most of them suffer from various comorbidities. They usually receive complex pharmacotherapy with large number of medicines which increase the risk of drug-drug interactions (DDIs). Objective The present repor...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0340-3
更新日期：2016-10-01 00:00:00
abstract：:Background Implementation of clinical medication reviews in daily practice is scarcely evaluated. The Opti-Med intervention applied a structured approach with external expert teams (pharmacist and physician) to conduct medication reviews. The intervention was effective with respect to resolving drug related problems, ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-018-0615-y
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Both clinical pharmacists and computerized physician order entry systems with clinical decision support (CPOE/CDSS) can reduce drug-related problems (DRPs). However, the contribution of a clinical pharmacist in addition to CPOE/CDSS has not been established in a prospective study. OBJECTIVE:To determine whi...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-013-9798-4
更新日期：2013-10-01 00:00:00
abstract：:Background The challenges of under-reporting of adverse drug reactions have been identified as a major setback for the pharmacovigilance system worldwide. Direct reporting by health care consumers has been adopted in some developed and developing countries with a positive impact in improving pharmacovigilance activiti...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章,评审
doi：10.1007/s11096-020-01141-x
更新日期：2020-09-09 00:00:00
abstract：BACKGROUND:There can be a lack of transfer of information between hospitals and community pharmacies following patient discharge, which puts patients at a high risk of suffering drug related problems (DRPs). Community pharmacy plays a vital role in identifying and solving these discharge DRPs and taking action before t...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9935-8
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Possessing correct therapeutic information on oral contraceptives is an important prerequisite for the provision of sound advice to women who are using these products. OBJECTIVES:This study examines Egyptian pharmacists' knowledge of pharmacotherapeutic aspects of oral contraceptives as well as interest in ...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0264-y
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:From 20 to 65 % of older adults receiving polypharmacy take at least one potentially inappropriate medication (PIM), leading to a high risk of adverse drug reactions. The term deprescribing was coined to describe a process of optimization of drug regimens through the withdrawal of PIMs. There is a paucity of...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0279-4
更新日期：2016-04-01 00:00:00
abstract：:Background Best practice guidelines recommend regular evaluation of antipsychotics in managing behaviours for dementia patients with a view to de-prescribing, given its significant mortality and adverse outcomes (Reus et al. in Am J Psychiatry 173(5):543-546, 2016, Deprescribing Guidelines and Algorithms in https://de...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-01135-9
更新日期：2020-09-10 00:00:00
abstract：:Background Dose banding (DB) is a strategy to rationalise antineoplastic production at Hospital Pharmacy Aseptic Compounding Units (ACUs) and to reduce patient's waiting time. DB allows for optimizing workflows and workloads, facilitating adoption of new technologies, and increasing safety, quality and efficiency of t...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-018-0714-9
更新日期：2018-10-01 00:00:00
abstract：:Background Pharmacists are increasingly involved in patient care. This new role in a complex healthcare system with demanding patients may lead to moral dilemmas. There has been little research into pharmacy ethics, and existing data are limited by their retrospective nature and small sample sizes. A thematic overview...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-017-0561-0
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:In Qatar, home diagnostic tests are available over the counter in community pharmacies. While possibly beneficial, these tests have the potential for harm if they are used in the absence of pharmacist counseling. OBJECTIVES:To determine the public views, level of awareness and use of home diagnostic tests a...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9687-2
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Medication discrepancies may occur at transitions in care and negatively impact patient outcomes. OBJECTIVE:To determine if involving clinical pharmacists in hospital care, medication reconciliation and discharge medication plan communication can reduce medication discrepancies with a prospective, randomize...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9917-x
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:No overview of preventive health activities conducted by pharmacists in South Germany has been available until now. Moreover, little about the needs of the public is known with regard to pharmacy-based preventive services. OBJECTIVES:To gain an overview of the preventive health services and campaigns carrie...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-012-9722-3
更新日期：2013-02-01 00:00:00
abstract：:Background Despite the importance placed on the concept of the multidisciplinary team in relation to intermediate care (IC), little is known about community pharmacists' (CPs) involvement. Objective To determine CPs' awareness of and involvement with IC services, perceptions of the transfer of patients' medication inf...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-016-0377-3
更新日期：2016-12-01 00:00:00
abstract：:Background Atopic dermatitis affects 10-20% of the children worldwide. Unfortunately not all patients who receive treatment have optimal treatment outcomes. Objective To assess the view of parents and pharmacy staff in order to optimize pharmaceutical care for young atopic dermatitis patients. Setting Community pharma...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-019-00827-1
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Complete control of emesis during chemotherapy remains to be achieved. This could be improved by increasing adherence to medicines and recommendations. OBJECTIVE:The aim of this study was to analyse the effects of pharmaceutical care on the incidence of delayed chemotherapy-induced nausea and vomiting (CINV...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-014-9915-z
更新日期：2014-04-01 00:00:00
abstract：:Background Off-label prescribing is prevalent in healthcare. There is a lack of understanding of pharmacists' attitudes toward the practice of off-label prescribing, especially those that are prescribed for other indications than approved ones (termed as indication-based off-label prescribing). Objective Explore hospi...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-017-0567-7
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Information on the use of ankylosing spondylitis (AS) therapies in clinical practice is a key factor in decision making, as more efficient treatments may involve substantial savings while maintaining the clinical benefits for the patient. OBJECTIVE:To assess the mean annual doses and associated costs of the...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-015-0124-1
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:A range of extended/enhanced pharmacy services (EPS) are increasingly being offered in community pharmacies following a global paradigm shift in professional pharmacy practice from a product-oriented focus to a patient-centered approach. A number of pharmacy/pharmacist characteristics have been reported to i...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-015-0127-y
更新日期：2015-10-01 00:00:00
abstract：:Background There is a lack of data on the prevalence of potentially inappropriate medications (PIMs) in community-dwelling older adults in China. Objective To assess the prevalence of potentially inappropriate medication in community dwelling older adults in China and to investigate risk factors associated with the us...
journal_title：International journal of clinical pharmacy
pub_type： 杂志文章
doi：10.1007/s11096-020-00980-y
更新日期：2020-04-01 00:00:00
