A functional investigation of the suppression of CpG and UpA dinucleotide frequencies in plant RNA virus genomes.

abstract：:Inhaled corticosteroids (ICSs) are widely prescribed in chronic obstructive pulmonary disease (COPD). However, little is known about predictors of ICSs therapeutic response. To investigate whether the variation in glucocorticoid-induced transcript 1 (GLCCI1) rs37973 is associated with ICS efficacy. A total of 204 clin...

journal_title：Scientific reports

authors： Lei Y,Gao Y,Chen J,Li M,Wu X,Ning Q,Zhao J,Xiong W,Xu Y,Xie J

更新日期：2017-02-10 00:00:00

abstract：:Emergent phases in the two-dimensional electron gas (2DEG) formed at the interface between two insulating oxides have attracted great attention in the past decade. We present ab-initio electronic structure calculations for the interface between a Mott insulator GdTiO3 (GTO) and a band insulator SrTiO3 (STO) and compar...

journal_title：Scientific reports

authors： Banerjee H,Banerjee S,Randeria M,Saha-Dasgupta T

更新日期：2015-12-22 00:00:00

abstract：:In this study, nanowires/nanowalls were generated on a silicon wafer through a chemical etching method. Octadecyltrichlorosilane (OTS) was deposited onto the nanowire/nanowall surfaces to alter their hydrophobicity. The hydrophobic characteristics of the surfaces were further modified via a 1.5-μm-thick layer of n-oct...

journal_title：Scientific reports

authors： Yilbas BS,Salhi B,Yousaf MR,Al-Sulaiman F,Ali H,Al-Aqeeli N

更新日期：2016-12-09 00:00:00

abstract：:The exact mechanism of endometriosis is unknown. The recommendation system (RS) based on item similarities of machine learning has never been applied to the relationship between diseases. The study aim was to identify diseases associated with endometriosis by applying RS based on item similarities to insurance data in...

journal_title：Scientific reports

authors： Lee JH,Kwon SY,Chang J,Yuk JS

更新日期：2019-04-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies. The genomic landscape of the PDAC genome features four frequently mutated genes (KRAS, CDKN2A, TP53, and SMAD4) and dozens of candidate driver genes altered at low frequency, including potential clinical targets. Circulating cell-free...

journal_title：Scientific reports

authors： Takai E,Totoki Y,Nakamura H,Morizane C,Nara S,Hama N,Suzuki M,Furukawa E,Kato M,Hayashi H,Kohno T,Ueno H,Shimada K,Okusaka T,Nakagama H,Shibata T,Yachida S

更新日期：2015-12-16 00:00:00

abstract：:Models of biological processes are often subject to different sources of noise. Developing an understanding of the combined effects of different types of uncertainty is an open challenge. In this paper, we study a variant of the susceptible-infective-recovered model of epidemic spread, which combines both agent-to-age...

journal_title：Scientific reports

authors： Herrerías-Azcué F,Galla T

更新日期：2017-10-11 00:00:00

abstract：:The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a clinical presentation...

journal_title：Scientific reports

authors： O'Neill SFD,Fidelman JM,Haarup LS,Lund C,Konner MB

更新日期：2020-10-19 00:00:00

abstract：:Light-sheet fluorescence microscopy (LSFM) has emerged as a powerful method for rapid and optically efficient 3D microscopy. Initial LSFM designs utilized a static sheet of light, termed selective plane illumination microscopy (SPIM), which exhibited shadowing artifacts and deteriorated contrast due to light scatterin...

journal_title：Scientific reports

authors： Glaser AK,Chen Y,Yin C,Wei L,Barner LA,Reder NP,Liu JTC

更新日期：2018-09-17 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia characterized by the formation of amyloid plaques (Aβ). Over the last decade, the important role of the innate immune system for the disease development has been established. Chronic activation of microglial cells creates a proinflammatory environment, which...

journal_title：Scientific reports

authors： Boza-Serrano A,Yang Y,Paulus A,Deierborg T

更新日期：2018-01-24 00:00:00

abstract：:We present a new class of TiBw/Ti6Al4V composites with a network reinforcement architecture that exhibits a significant creep resistance compared to monolithic Ti6Al4V alloys. Creep tests performed at temperatures between 773 K and 923 K and stress range of 100 MPa-300 MPa indicate both a significant improvement of th...

journal_title：Scientific reports

authors： Wang S,Huang LJ,Geng L,Scarpa F,Jiao Y,Peng HX

更新日期：2017-01-17 00:00:00

abstract：:The mobilities of electrons and holes determine the applicability of any semiconductor, but their individual measurement remains a major challenge. Here, we show that time-resolved terahertz spectroscopy (TRTS) can distinguish the mobilities of minority and majority charge carriers independently of the doping-type and...

journal_title：Scientific reports

authors： Hempel H,Hages CJ,Eichberger R,Repins I,Unold T

更新日期：2018-09-27 00:00:00

abstract：:High-performance ZnO-Pr6O11 thin-film varistors were fabricated simply by hot-dipping oxygen-deficient zinc oxide thin films in Pr6O11 powder. The films had a composition of ZnO0.81 and a thickness of about 200 nm, which were deposited by radio frequency magnetron sputtering a sintered zinc oxide ceramic target. Speci...

journal_title：Scientific reports

authors： Wang Y,Peng Z,Wang Q,Wang C,Fu X

更新日期：2017-02-03 00:00:00

abstract：:Patterns of temperature fluctuations in nature affect numerous biological processes, yet, empirical studies often utilize constant temperature treatments. This can limit our understanding of how thermally sensitive species respond to ecologically relevant temperatures. Research on turtles with temperature-dependent se...

journal_title：Scientific reports

authors： Carter AW,Sadd BM,Tuberville TD,Paitz RT,Bowden RM

更新日期：2018-01-08 00:00:00

abstract：:Rab small GTPases play key roles in intracellular membrane trafficking. Rab33a promotes axon outgrowth of cultured rat hippocampal neurons by mediating the anterograde axonal transport of Golgi-derived vesicles and the concomitant exocytosis of these vesicles at the growth cone. However, the functions of Rab33 in vivo...

journal_title：Scientific reports

authors： Huang L,Urasaki A,Inagaki N

更新日期：2019-02-12 00:00:00

abstract：:The salamander chytrid fungus (Batrachochytrium salamandrivorans [Bsal]) is causing massive mortality of salamanders in Europe. The potential for spread via international trade into North America and the high diversity of salamanders has catalyzed concern about Bsal in the U.S. Surveillance programs for invading patho...

journal_title：Scientific reports

authors： Waddle JH,Grear DA,Mosher BA,Grant EHC,Adams MJ,Backlin AR,Barichivich WJ,Brand AB,Bucciarelli GM,Calhoun DL,Chestnut T,Davenport JM,Dietrich AE,Fisher RN,Glorioso BM,Halstead BJ,Hayes MP,Honeycutt RK,Hossack BR,Kle

更新日期：2020-08-03 00:00:00

abstract：:Although the clinical importance of extragraft bone formation (ExGBF) and bridging (ExGBB) has been reported, few studies have investigated the biomechanical influences of ExGBF on the motion segment. In this study, ExGBF was simulated at the C5-C6 motion segment after anterior cervical discectomy and fusion using a d...

journal_title：Scientific reports

authors： Park WM,Jin YJ

更新日期：2019-12-11 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep31347. ...

journal_title：Scientific reports

authors： Zhu W,Wang L,Dong Z,Chen X,Song F,Liu N,Yang H,Fu J

更新日期：2018-05-11 00:00:00

abstract：:One of the key motivations in producing 3D structures has always been the realization of metamaterials with effective constituent properties that can be tuned in all propagation directions at various frequencies. Here, we report the investigation of spatially oriented "Nanograter" structures with orientation-dependent...

journal_title：Scientific reports

authors： Liu Z,Cui A,Gong Z,Li H,Xia X,Shen TH,Li J,Yang H,Li W,Gu C

更新日期：2016-06-30 00:00:00

abstract：:Honeybee pupae morphology can be affected by a number of stressor, but in vivo investigation is difficult. A computed tomography (CT) technique was applied to visualize a comb's inner structure without damaging the brood. The CT scan was performed on a brood comb containing pupae developed from eggs laid by the queen ...

journal_title：Scientific reports

authors： Facchini E,Nalon L,Andreis ME,Di Giancamillo M,Rizzi R,Mortarino M

更新日期：2019-07-23 00:00:00

abstract：:Intravitreal anti-vascular endothelial growth factor (VEGF) agents can treat macular edema (ME) in branch retinal vein occlusion (BRVO). However, refractory ME, the mechanism of which is not well elucidated, occurs frequently. Sixty-six eyes with ME secondary to BRVO were enrolled in this retrospective observational c...

journal_title：Scientific reports

authors： Tomiyasu T,Hirano Y,Yoshida M,Suzuki N,Nishiyama T,Uemura A,Yasukawa T,Ogura Y

更新日期：2016-07-08 00:00:00

abstract：:With approximately 1,500 extant species, freshwater crabs (Decapoda: Brachyura) are among the most diverse decapod crustaceans. Nevertheless, their fossil record is extremely limited: only Potamidae, Potamonautidae and Trichodactylidae are reported up to the Eocene of the Neotropics so far. This work documents unusual...

journal_title：Scientific reports

authors： Robin N,van Bakel BWM,Hyžný M,Cincotta A,Garcia G,Charbonnier S,Godefroit P,Valentin X

更新日期：2019-12-27 00:00:00

abstract：:In the present work, a catalyst-free physical vapour deposition method is used to synthesize high yield of Bi2Se3 nanoribbons. By replacing standard glass or quartz substrates with aluminium covered with ultrathin porous anodized aluminium oxide (AAO), the number of synthesized nanoribbons per unit area can be increas...

journal_title：Scientific reports

authors： Kunakova G,Meija R,Andzane J,Malinovskis U,Petersons G,Baitimirova M,Bechelany M,Bauch T,Lombardi F,Erts D

更新日期：2019-08-05 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Yun JH,Cho DH,Lee B,Kim HS,Chang YK

更新日期：2020-02-20 00:00:00

abstract：:High mortality and dependent living after hip fracture pose a significant public health concern. Retrospective study was conducted with 481 hip fracture patients (≥65 years of age) undergoing surgery from March 2009 to May 2014. The Hip-MFS was calculated by Comprehensive Geriatric Assessment (CGA). The primary outcom...

journal_title：Scientific reports

authors： Choi JY,Cho KJ,Kim SW,Yoon SJ,Kang MG,Kim KI,Lee YK,Koo KH,Kim CH

更新日期：2017-02-24 00:00:00

abstract：:The development of 2D nanomaterial coatings across metal surfaces is a challenge due to the mismatch between the metal microstructure and the nanoscale materials. The naturally occurring thin oxidative layer present across all metal surfaces, may lead to low adherence and connectivity. In this paper, graphene/titania/...

journal_title：Scientific reports

authors： Yi Z,Merenda A,Kong L,Radenovic A,Majumder M,Dumée LF

更新日期：2018-05-25 00:00:00

abstract：:Pupillary light reflex (PLR) is an involuntary response where the pupil size changes with luminance. Studies have shown that PLR response was altered in children with autism spectrum disorders (ASDs) and other neurological disorders. However, PLR in infants and toddlers is still understudied. We conducted a longitudin...

journal_title：Scientific reports

authors： Kercher C,Azinfar L,Dinalankara DMR,Takahashi TN,Miles JH,Yao G

更新日期：2020-01-27 00:00:00

abstract：:Particle transport phenomena in the deep alveolated airways of the lungs (i.e. pulmonary acinus) govern deposition outcomes following inhalation of hazardous or pharmaceutical aerosols. Yet, there is still a dearth of experimental tools for resolving acinar particle dynamics and validating numerical simulations. Here,...

journal_title：Scientific reports

authors： Fishler R,Hofemeier P,Etzion Y,Dubowski Y,Sznitman J

更新日期：2015-09-11 00:00:00

abstract：:Degradation of the biologically potent octapeptide angiotensin Ang II-(1-8) is mediated by the activities of several peptidases. The conversion of Ang II to the septapeptide Ang-(1-7) is of particular interest as the latter also confers organ protection. The conversion is catalyzed by angiotensin-converting enzyme 2 a...

journal_title：Scientific reports

authors： Liu P,Wysocki J,Serfozo P,Ye M,Souma T,Batlle D,Jin J

更新日期：2017-04-05 00:00:00

abstract：:High-quality broadband ultrasound transducers yield superior imaging performance in biomedical ultrasonography. However, proper design to perfectly bridge the energy between the active piezoelectric material and the target medium over the operating spectrum is still lacking. Here, we demonstrate a new anisotropic cone...

journal_title：Scientific reports

authors： Li Z,Yang DQ,Liu SL,Yu SY,Lu MH,Zhu J,Zhang ST,Zhu MW,Guo XS,Wu HD,Wang XL,Chen YF

更新日期：2017-02-17 00:00:00

abstract：:Here, we assessed the sulfated derivative of the microbial polysaccharide gellan gum and derivatives of λ and κ-carrageenans for their ability to inhibit Plasmodium falciparum 3D7 and Dd2 growth and invasion of red blood cells in vitro. Growth inhibition was assessed by means of flow cytometry after a 96-h exposure to...

journal_title：Scientific reports

authors： Recuenco FC,Kobayashi K,Ishiwa A,Enomoto-Rogers Y,Fundador NG,Sugi T,Takemae H,Iwanaga T,Murakoshi F,Gong H,Inomata A,Horimoto T,Iwata T,Kato K

更新日期：2014-04-17 00:00:00