Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yun JH,Cho DH,Lee B,Kim HS,Chang YKdoi
10.1038/s41598-020-60509-1subject
Has Abstractpub_date
2020-02-20 00:00:00pages
3429issue
1issn
2045-2322pii
10.1038/s41598-020-60509-1journal_volume
10pub_type
已发布勘误abstract::The FDA-approved prophylactic antimalarial drug atovaquone (ATO) recently was repurposed as an antitumor drug. Studies show that ATO exerts a profound antiproliferative effect in several cancer cells, including breast, ovarian, and glioma. Analogous to the mechanism of action proposed in parasites, ATO inhibits mitoch...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74808-0
更新日期:2020-10-21 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-68522-0
更新日期:2020-07-10 00:00:00
abstract::The study of organic/inorganic molecules with activity against intracellular fungi of the phylum Microsporidia is of critical importance. Here, for the first time, the inactivation of these parasitic fungi by porphyrins is reported. The biological effects of porphyrins (10 µM and 100 µM) on the microsporidian Nosema c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23678-8
更新日期:2018-04-03 00:00:00
abstract::The poor control of the adhesion of TiO2 nanotubes (TNTs) layers to a non-anodized titanium (Ti) substrate has limited their widespread application, because the stripping mechanism has not yet been revealed. Here, we report a novel method to control the detachment of TNTs by post-treatment of the as-fabricated samples...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07178
更新日期:2014-11-24 00:00:00
abstract::Concussions carry devastating potential for cognitive, neurologic, and socio-emotional disease, but no objective test reliably identifies a concussion and its severity. A variety of neurological insults compromise sound processing, particularly in complex listening environments that place high demands on brain process...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39009
更新日期:2016-12-22 00:00:00
abstract::Central nervous system-specific proteins (CSPs), transported across the damaged blood-brain-barrier (BBB) to cerebrospinal fluid (CSF) and blood (serum), might be promising diagnostic, prognostic and predictive protein biomarkers of disease in individual multiple sclerosis (MS) patients because they are not expected t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06210
更新日期:2014-09-03 00:00:00
abstract::Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic and eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find that even small amounts of polymer in solution can drastically change E. co...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15761
更新日期:2015-10-28 00:00:00
abstract::Epidemiological studies have shown that atherosclerotic risk factors accelerate the pathological process underlying Alzheimer's disease (AD) via chronic cerebral hypoperfusion. In this study, we aimed to clarify the mechanisms by which cerebral hypoperfusion may exacerbate AD pathology. We applied bilateral common car...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39494-7
更新日期:2019-02-26 00:00:00
abstract::Heavy metals are environmental pollutants affect the integrity and distribution of living organisms in the ecosystem and also humans across the food chain. The study targeted the removal of copper (Cu2+) from aqueous solutions, depending on the biosorption process. The bacterial candidate was identified using 16S rRNA...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66101-x
更新日期:2020-06-11 00:00:00
abstract::This research is emphasized to describe the stability analysis in the form of dual solution of the flow and heat analysis on nanofluid over an exponential stretching cylindrical surface containing microorganisms. The research is also implemented to manifest the dual profiles of velocity, temperature and nanoparticle c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72545-y
更新日期:2020-10-12 00:00:00
abstract::Strategies adopted by individuals in a social network significantly impact the network, and they strongly affect relationships between individuals in the network. Links between individuals also heavily influence their levels of cooperation. Taking into account the evolution of each individual's connection, we explore ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45237
更新日期:2017-03-24 00:00:00
abstract::Omono River virus (OmRV) is a double-stranded RNA virus isolated from Culex mosquitos, and it belongs to a group of unassigned insect viruses that appear to be related to Totiviridae. This paper describes electron cryo-microscopy (cryoEM) structures for the intact OmRV virion to 8.9 Å resolution and the structure of t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33170
更新日期:2016-09-12 00:00:00
abstract::Emergence of a highly pathogenic avian influenza (HPAI) H5N8 virus in Asia and its spread to Europe and North America has caused great concern for human health. Although the H5N8 virus has been only moderately pathogenic to mammalian hosts, virulence can still increase. We evaluated the pathogenic potential of several...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40667
更新日期:2017-01-17 00:00:00
abstract::Solution-processed gate dielectrics were fabricated with the combined ZrO2 and Al2O3 (ZAO) in the form of mixed and stacked types for oxide thin film transistors (TFTs). ZAO thin films prepared with double coatings for solid gate dielectrics were characterized by analytical tools. For the first time, the capacitance o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33576
更新日期:2016-09-19 00:00:00
abstract::For a high-performance cocatalyst-modified photocatalyst, an effective interfacial separation of photogenerated electron from its corresponding holes and its following reduction reaction at the active sites are highly required. However, it is difficult for a single-component cocatalyst to simultaneously realize the cr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13083
更新日期:2015-08-14 00:00:00
abstract::Humans bargaining over money tend to reject unfair offers, whilst chimpanzees bargaining over primary rewards of food do not show this same motivation to reject. Whether such reciprocal fairness represents a predominantly human motivation has generated considerable recent interest. We induced either moderate or severe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00593
更新日期:2012-01-01 00:00:00
abstract::In this study, we have employed graphene oxide as a matrix to simultaneously and directly quantify serum nonesterified and esterified fatty acids (FAs) using matrix-assisted laser/desorption ionization-Fourier transform ion cyclotron resonance mass spectrometry (MALDI-FTICR MS). Twelve serum nonesterified FAs combined...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34201
更新日期:2016-09-30 00:00:00
abstract::The role of the smoothelin-like 1 (SMTNL1) protein in mediating vascular smooth muscle contractile responses to intraluminal pressure was examined in resistance vessels. Mesenteric arterioles from wild type (WT) and SMTNL1 global knock-out (KO) mice were examined with pressure myography. SMTNL1 deletion was associated...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36564-0
更新日期:2019-01-24 00:00:00
abstract::William Adams (Miura Anjin) was an English navigator who sailed with a Dutch trading fleet to the far East and landed in Japan in 1600. He became a vassal under the Shogun, Tokugawa Ieyasu, was bestowed with a title, lands and swords, and became the first SAMURAI from England. "Miura" comes from the name of the territ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78723-2
更新日期:2020-12-10 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-23132-9
更新日期:2018-03-19 00:00:00
abstract::Long-term high-fat diet (HFD) consumption leads to not only obese-insulin resistance, but also impaired left ventricular (LV) function. Vagus nerve stimulation (VNS) has been shown to exert cardioprotection. However, its effects on the heart and metabolic parameters under obese-insulin resistant condition is not known...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19749
更新日期:2016-02-01 00:00:00
abstract::When humans fail to make optimal decisions in strategic games and economic gambles, researchers typically try to explain why that behaviour is biased. To this end, they search for mechanisms that cause human behaviour to deviate from what seems to be the rational optimum. But perhaps human behaviour is not biased; per...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34102
更新日期:2016-09-28 00:00:00
abstract::The chloride gradient plays an important role in regulating cell volume, membrane potential, pH, secretion, and the reversal potential of inhibitory glycine and GABAA receptors. Measurement of intracellular chloride activity, [Formula: see text], using liquid membrane ion-selective microelectrodes (ISM), however, has ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54885-6
更新日期:2019-12-11 00:00:00
abstract::Antitumor drug development based on the concept of intervening in the antioxidant system of cancer cells has been gaining increased interest. In this study, we propose a promising strategy for cancer treatment using modulation of oxidative stress by suppression of glutathione S-transferases (GSTs), a typical antioxida...
journal_title:Scientific reports
pub_type: 杂志文章,收录出版
doi:10.1038/s41598-019-51462-9
更新日期:2019-10-14 00:00:00
abstract::The proton exchange membrane fuel cells are the promising sustainable energy sources. The present study focuses on the enhancement the fuel cell performance and the protection of the stainless steel bipolar plate from the corrosion using polyaniline/Zn-Porphyrin composites coatings. The electrochemical properties (pol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60288-9
更新日期:2020-02-24 00:00:00
abstract::The vitally important skin barrier is formed by extensive cross-linking activity of transglutaminases (TGs) during terminal epidermal differentiation. We have previously shown that epidermal deficiency of a disintegrin and metalloproteinase 17 (ADAM17), the principal EGFR ligand sheddase, results in postnatal skin bar...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39780
更新日期:2016-12-22 00:00:00
abstract::Hybridization between heterospecific individuals has been documented as playing a direct role in promoting paternal leakage and mitochondrial heteroplasmy in both natural populations and laboratory conditions, by relaxing the egg-sperm recognition mechanisms. Here, we tested the hypothesis that hybridization can lead ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55764-w
更新日期:2019-12-16 00:00:00
abstract::Ethiopian mustard (Brassica carinata A. Braun) is an emerging sustainable source of vegetable oil, in particular for the biofuel industry. The present study exploited genome assemblies of the Brassica diploids, Brassica nigra and Brassica oleracea, to discover over 10,000 genome-wide SNPs using genotype by sequencing ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-69255-w
更新日期:2020-07-28 00:00:00
abstract::Our previous studies indicated that combination of Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and PPARγ ligand Troglitazone (TZD), can induce significant apoptosis in various TRAIL-resistant prostate and hepatocellular carcinoma (HCC) cells. These also suggested serine/threonine kinase AMP-activat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23780-x
更新日期:2018-04-03 00:00:00
abstract::The spinal dorsal horn (SDH) is comprised of distinct neuronal populations that process different somatosensory modalities. Somatostatin (SST)-expressing interneurons in the SDH have been implicated specifically in mediating mechanical pain. Identifying the transcriptomic profile of SST neurons could elucidate the uni...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25110-7
更新日期:2018-05-01 00:00:00