Effects of Hormonal Contraceptives on Mood: A Focus on Emotion Recognition and Reactivity, Reward Processing, and Stress Response.

Abstract:

PURPOSE OF REVIEW:We review recent research investigating the relationship of hormonal contraceptives and mood with a focus on relevant underlying mechanisms, such as emotion recognition and reactivity, reward processing, and stress response. RECENT FINDINGS:Adverse effects of hormonal contraceptives (HCs) on mood seem most consistent in women with a history of depressive symptoms and/or previous negative experience with HC-intake. Current evidence supports a negativity bias in emotion recognition and reactivity in HC-users, although inconsistent to some extent. Some data, however, do indicate a trend towards a blunted reward response and a potential dysregulation of the stress response in some HC-users. HC-effects on psychological and neurophysiological mechanisms underlying mood are likely context-dependent. We provide suggestions on how to address some of the contributing factors to this variability in future studies, such as HC-dose, timing, administration-mode, and individual risk. A better understanding of how and when HCs affect mood is critical to provide adequate contraceptive choices to women worldwide.

journal_name

Curr Psychiatry Rep

authors

Lewis CA,Kimmig AS,Zsido RG,Jank A,Derntl B,Sacher J

doi

10.1007/s11920-019-1095-z

subject

Has Abstract

pub_date

2019-11-07 00:00:00

pages

115

issue

11

eissn

1523-3812

issn

1535-1645

pii

10.1007/s11920-019-1095-z

journal_volume

21

pub_type

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