Misdiagnosed and mismanaged atypical spinal tuberculosis: A case series report.

abstract：:Delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) is a serious complication that occurs several days or weeks after carbon monoxide (CO) intoxication. This study identified computed tomography (CT) findings in the prediction of DEACMP development. Adults with CO poisoning admitted to Beijing Chaoya...

journal_title：Experimental and therapeutic medicine

authors： Du X,Gu H,Hao F,Gao L,Wang J,Sun C,Zhang H,Ma P,Zhang X,Hu W

更新日期：2019-04-01 00:00:00

abstract：:β-elemene is a novel, plant-derived anticancer drug, which has been used to target multiple solid tumor types. Hyperthermia is an adjuvant therapeutic modality to treat cancer. However, the underlying mechanisms associated with the efficacy of these two treatments are largely unknown. The aim of the present study was ...

journal_title：Experimental and therapeutic medicine

authors： Wu Z,Wang T,Zhang Y,Zheng Z,Yu S,Jing S,Chen S,Jiang H,Ma S

更新日期：2017-06-01 00:00:00

abstract：:On December 31, 2019, the first case of a novel coronavirus infection was reported in Wuhan, China. The ongoing outbreak of the 2019 novel coronavirus (2019-nCoV) has caused immense global concern. According to the recommendations of the International Health Regulations Emergency Committee and the facts and cases that...

journal_title：Experimental and therapeutic medicine

authors： Feng X,Xie X,Song S,Chen W,Bian H,Rui F,Zhu Q,Ren W,Qin C,Qi J

更新日期：2021-01-01 00:00:00

abstract：:The aim of the present study was to investigate the possible mechanism of Janus kinase (JAK)-signal transduction and activator of transcription (STAT)/PSMβ3 signaling in the occurrence of asthenozoospermia. We examined seminal fluid samples from 30 cases of asthenozoospermia and 30 healthy controls. Sperm was collecte...

journal_title：Experimental and therapeutic medicine

authors： Li J,Zhang L,Li B

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to investigate the clinical features of ulcerative colitis (UC) combined with acute interstitial lung disease (ILD). One case with acute UC combined with ILD and airway disease was reported, and the pathological diagnosis of previous cases of UC combined with ILD was retrospectively analyzed ...

journal_title：Experimental and therapeutic medicine

authors： Xu L,Xiao W,Ma D,Zhou S,Zhang Q

更新日期：2014-10-01 00:00:00

abstract：:DNA methylation is known to regulate the expression of numerous genes but its role in the pathogenesis of thoracic aortic dissection (TAD) has remained largely elusive. In the present study, the DNA methylome of patients with TAD was analyzed using a methylation microarray and bisulfite pyrosequencing was used to dete...

journal_title：Experimental and therapeutic medicine

authors： Li N,Lin H,Zhou H,Zheng D,Xu G,Shi H,Zhu X,Gao J,Shao G,Sun L

更新日期：2020-08-01 00:00:00

abstract：:The present study aims to raise awareness about the necessity of a thorough differential diagnosis process when diagnosing paraganglioma as it is an extremely rare entity with a high malignant potential. A 64-year-old female patient was admitted to the hospital with symptoms of bowel obstruction and a palpable abdomin...

journal_title：Experimental and therapeutic medicine

authors： Iliesiu A,Ungureanu IA,Petca A,Constantin MM,Petca RC,Sandru F,Constantin T,Dumitrascu MC

更新日期：2020-09-01 00:00:00

abstract：:Endometriosis is a common reproductive disorder in women, with a global prevalence of 10-15%. Long noncoding RNAs (lncRNAs) are critical to gene transcription, cell cycle modulation and immune response. The lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) reportedly mediates autophagy of endometr...

journal_title：Experimental and therapeutic medicine

authors： Liu X,Zhang P,Li Y,Zhao N,Han H

更新日期：2021-01-01 00:00:00

abstract：:Many studies have found the function of nitric oxide (NO) in cancer as a pro-neoplastic vs. an anti-neoplastic effector, but the role of NO in hepatocellular carcinoma (HCC) remains unclear. The present study aimed to investigate the effects of nitric oxide (NO) on the biological behavior of the human hepatocellular c...

journal_title：Experimental and therapeutic medicine

authors： Zhou L,Zhang H,Wu J

更新日期：2016-05-01 00:00:00

abstract：:Natural killer (NK) cells are innate lymphocytes that aid in the protection of the host from infectious diseases and cancer. In vitro studies of NK cells have provided a foundation for developing clinical adoptive NK-cell transferred immunotherapy against human tumors. To elucidate the functions and mechanisms of NK c...

journal_title：Experimental and therapeutic medicine

authors： Wang G,Yu G,Wang D,Guo S,Shan F

更新日期：2017-05-01 00:00:00

abstract：:Endotoxin tolerance is an immunohomeostatic reaction to reiterant lipopolysaccharide (LPS) exposure that maintains a state of altered responsiveness in immune cells, resulting in the inhibition of the pro-inflammatory response and the resolution of inflammation. Microglia constitutes the first line of defense against ...

journal_title：Experimental and therapeutic medicine

authors： Sun X,Sun J,Shao X,Feng J,Yan J,Qin Y

更新日期：2018-06-01 00:00:00

abstract：:Obstructive salivary gland diseases are common conditions that arise following the disruption of the secretary ductal system and usually results in the swelling and pain of the affected gland(s). There has been an increase in the use of sialendoscopy for the treatment and diagnosis of obstructive salivary gland infect...

journal_title：Experimental and therapeutic medicine

authors： Ding YF,Tseng H,Su CH,Tai CC,Wu YY,Haung CJ,Lee CS,Hung SH

更新日期：2019-04-01 00:00:00

abstract：:A 58-year-old female exhibited the onset of symmetrical sensory abnormalities of the face and extremities. The neurological examination revealed normal muscle strength with abated or absent tendon reflexes. The patient experienced symmetrical glove- and stocking-type pinprick sensations in the distal extremities and a...

journal_title：Experimental and therapeutic medicine

authors： Zhang J,Liu N,Zhang ZC,Zheng RZ,Li Q

更新日期：2014-12-01 00:00:00

abstract：:A combination of docetaxel (D) and cisplatin (P) is one of the standard regimens for the initial treatment of advanced non-small cell lung cancer (NSCLC). Yet, the toxicity of D administered at 75 mg/m(2) in three weekly doses to patients is a concern. The aim of this study was to assess the efficacy of a lower combin...

journal_title：Experimental and therapeutic medicine

authors： Kim KS,Oh IJ,Ban HJ,Cho HJ,Kwon YS,Kim YI,Lim SC,Na KJ,Song SY,Choi S,Choi YD,Kim YC

更新日期：2012-08-01 00:00:00

abstract：:The diaphragm is an important respiratory organ. The aim of this study was to quantitatively evaluate the longitudinal deformation of the right hemidiaphragm in normal subjects using two-dimensional strain ultrasound speckle tracking. Twenty-one healthy subjects were enrolled in this study. GE Healthcare Vivid E9 equi...

journal_title：Experimental and therapeutic medicine

authors： Ye X,Xiao H,Bai W,Liang Y,Chen M,Zhang S

更新日期：2013-08-01 00:00:00

abstract：:The present study determined the expression of microRNA (miR)-663 in hypertrophic scar (HS) tissues and investigate the regulatory mechanisms of miR-663 in HS. A total of 51 patients diagnosed with HS between December 2013 and February 2016 were included in the present study. HS tissues (experimental group) and HS-adj...

journal_title：Experimental and therapeutic medicine

authors： Chen Q,Zhao T,Xie X,Yu D,Wu L,Yu W,Sun W

更新日期：2018-08-01 00:00:00

abstract：:Aortic valve (AoV) stenosis is the third most common cardiovascular disease. The pathogenesis of AoV stenosis is associated with an inflammatory process where MMPs serve important roles. The aim of the present study was to determine the association between matrix metalloproteinases (MMPs), tissue inhibitors of metallo...

journal_title：Experimental and therapeutic medicine

authors： Lurins J,Lurina D,Svirskis S,Nora-Krukle Z,Tretjakovs P,Mackevics V,Lejnieks A,Rapisarda V,Baylon V

更新日期：2019-04-01 00:00:00

abstract：:Nerve growth factor (NGF) and dendritic cells (DCs) have been hypothesized to modulate T cell responses in a mouse model of asthma. However, whether NGF plays a role in regulating the maturation and polarization of lung DCs remains unclear. In the present study, the effect of NGF inhibition on the maturation and pheno...

journal_title：Experimental and therapeutic medicine

authors： Qin Q,Wang Z,Pan P,Cao Z,Xia Q,Tan H,Hu C

更新日期：2014-11-01 00:00:00

abstract：:Malignant melanoma is the most aggressive neoplasm, with severe metastatic potential. microRNAs represent a class of endogenously expressed, small non-coding RNAs that regulate gene expression. As a consequence, the translation of these mRNAs is inhibited or they are destabilized resulting in downregulation of the enc...

journal_title：Experimental and therapeutic medicine

authors： Yamazaki H,Chijiwa T,Inoue Y,Abe Y,Suemizu H,Kawai K,Wakui M,Furukawa D,Mukai M,Kuwao S,Saegusa M,Nakamura M

更新日期：2012-05-01 00:00:00

abstract：:Cyclooxygenase (COX)-2 inhibitors are widely used for postoperative pain control in clinical practice. However, it is unknown whether spinal sensitization is involved in the analgesic effects of COX-2 inhibitors on surgical pain. Extracellular signal-regulated kinase (ERK) in the spinal cord is implicated in various t...

journal_title：Experimental and therapeutic medicine

authors： Guo YJ,Shi XD,Fu D,Yang Y,Wang YP,Dai RP

更新日期：2013-07-01 00:00:00

abstract：:Kidney morphology has been used to estimate renal functions. The present study investigated the usefulness of kidney length and renal parenchymal volume (RPV) measured using three-dimensional ultrasonography (3-D USG) in estimating renal pathological findings, and the outcome in patients with nephropathy who underwent...

journal_title：Experimental and therapeutic medicine

authors： Xu J,Hwang SI,Lee HJ,Chin HJ

更新日期：2018-02-01 00:00:00

abstract：:Lung cancer is among the most common causes of cancer-related mortality. It has a high mortality rate and resistance to chemotherapy due to its high metastatic potential. Naringenin, a bioactive compound identified in several fruits, displays anti-inflammatory and antitumor effects. Furthermore, naringenin mitigates t...

journal_title：Experimental and therapeutic medicine

authors： Chang HL,Chang YM,Lai SC,Chen KM,Wang KC,Chiu TT,Chang FH,Hsu LS

更新日期：2017-02-01 00:00:00

abstract：:Endometriosis (EM) is a common benign gynecological disorder. The present study aimed to investigate the potential role of propofol, a commonly used intravenous anesthetic agent, in the pathogenesis of EM. The EM cell line CRL-7566 was used in the present study. CRL-7566 cells were first treated with various concentra...

journal_title：Experimental and therapeutic medicine

authors： Feng S,Sun Y

更新日期：2018-10-01 00:00:00

abstract：:Aged garlic extract (AGE) produced by the aging process has various beneficial pharmacological effects. In this study, the effects of AGE on fatty liver, insulin resistance and intestinal microbiota were compared between ddY-H mice, an insulin resistance mouse, and ddY-L mice, normal mice. Mice were fed an AGE-supplem...

journal_title：Experimental and therapeutic medicine

authors： Maeda T,Miki S,Morihara N,Kagawa Y

更新日期：2019-07-01 00:00:00

abstract：:Application value of the minimally invasive puncture and small bone window craniotomy in hypertensive intracerebral hemorrhage was investigated to explore the effects of the above treatment methods on motor-evoked potentials (MEPs) and postoperative rehemorrhage. Patients with hypertensive intracerebral hemorrhage who...

journal_title：Experimental and therapeutic medicine

authors： Luan L,Li M,Sui H,Li G,Pan W

更新日期：2019-02-01 00:00:00

abstract：:Chemotherapy-induced anorexia (CIA), which may lead to severe nutrition-associated problems, is a common complication associated with anti-cancer therapies. In the present study, the anti-anorexigenic effect of electroacupuncture (EA) was explored through assessing a change in appetite-associated peptides and c-Fos ex...

journal_title：Experimental and therapeutic medicine

authors： Kang KS,Huh W,Bang Y,Choi HJ,Baek JY,Song JH,Kang JW,Kim TH

更新日期：2019-04-01 00:00:00

abstract：:Stress-related mucosal disease (SRMD) is a common complication in patients in the intensive care unit (ICU). The aim of the present study was to investigate the possible mechanisms for the pathogenesis of SRMD. In total, 38 patients with SRMD were enrolled from an ICU, as well as 15 healthy volunteers. The disease sev...

journal_title：Experimental and therapeutic medicine

authors： Wang X,Zhao Q,Shi H,Qi F,Shi N,Bai D,Li X,Yuan H,Zuo X

更新日期：2020-11-01 00:00:00

abstract：:The aim of the present study was to investigate the expression and role of transforming growth factor (TGF)-β1/phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3KC3) in the peripheral blood in patients with hypertension. A total of 28 patients with primary hypertension and 20 healthy control subjects were inc...

journal_title：Experimental and therapeutic medicine

authors： Zhang Q,Liu H,Yang J

更新日期：2019-03-01 00:00:00

abstract：:The present study aimed to determine the clinical characteristics and perinatal outcomes of females with severe preeclampsia according to their pre-pregnancy body mass index (BMI). Data from 233 patients with severe preeclampsia were reviewed from the Inpatient Obstetrics Department. The data were divided into 3 group...

journal_title：Experimental and therapeutic medicine

authors： Jiang L,Lin J,Yan J,Lin X,Han Q,Zhang H

更新日期：2020-07-01 00:00:00

abstract：:MicroRNA (miR)-199b-5p has been reported to have a critical role in various types of malignancy. However, the exact function miR-199b-5p in renal cancer remains to be fully elucidated. The present study aimed to detect the expression levels of miR-199b-5p in renal cell carcinoma (RCC) tissues and RCC cell lines, and i...

journal_title：Experimental and therapeutic medicine

authors： Lai Y,Quan J,Lin C,Li H,Hu J,Chen P,Xu J,Guan X,Xu W,Lai Y,Ni L

更新日期：2018-07-01 00:00:00