Lung dendritic cells undergo maturation and polarization towards a T helper type 2-stimulating phenotype in a mouse model of asthma: Role of nerve growth factor.

abstract：:The aim of this study was to compare the results of immunohistochemistry (IHC) assays evaluated by human examiners with the results evaluated by computerized image analysis, and to compare the computerized image analysis results among three automated IHC assays, namely the BioGenex, Dako and Ventana assays. All slides...

journal_title：Experimental and therapeutic medicine

authors： Arihiro K,Oda M,Ogawa K,Tominaga K,Kaneko Y,Shimizu T,Ohnishi S,Oda M,Kurita Y,Taira Y,Fujii M,Tanaka M

更新日期：2010-11-01 00:00:00

abstract：:The aim of this study was to analyze the clinical features of hepatitis B surface antigen (HBsAg)-positive and negative diffuse large B-cell lymphomas (DLBCLs) and to compare the outcomes and serum hepatitis B virus (HBV)-DNA loads of patients treated with cyclophosphamide, doxorubicin, vincristine and prednisone (CHO...

journal_title：Experimental and therapeutic medicine

authors： Xie W,Zhou D,Hu K,Xiao X,Huang W,He J,Shi J,Luo Y,Zhang J,Lin M,Cai Z,Huang H,Ye X

更新日期：2013-07-01 00:00:00

abstract：:The rabbit VX2 hepatic tumor model has been widely used for the investigation of liver cancer. The present study was designed to compare two inoculation methods in order to identify an improved modality for establishing rabbit hepatic tumors. A total of 44 rabbits were randomly divided into 2 groups. All inoculations ...

journal_title：Experimental and therapeutic medicine

authors： Sun JH,Zhang YL,Nie CH,Yu XB,Xie HY,Zhou L,Zheng SS

更新日期：2012-03-01 00:00:00

abstract：:Lipid peroxidation is associated with several metabolic diseases. Lipid peroxidation causes cellular damage through reactive aldehyde species such as 4-hydroxyonenal (4-HNE). The exact mechanism(s) by which 4-HNE causes damage in the intravascular compartment is not yet exactly understood. Using an in vitro system, th...

journal_title：Experimental and therapeutic medicine

authors： Mustafa AG,Alfaqih MA,Al-Shboul O

更新日期：2018-09-01 00:00:00

abstract：:Schwannomas are benign encapsulated tumors arising from Schwann cells in the peripheral nervous system. Between 25 and 45% of schwannomas occur in the head and neck region. Schwannomas of the larynx are extremely rare with an incidence of 0.1-1.5% in all benign laryngeal tumors. Laryngeal schwannomas usually occur in ...

journal_title：Experimental and therapeutic medicine

authors： Wang B,Dong P,Shen B,Xu H,Zheng J

更新日期：2014-04-01 00:00:00

abstract：:Acyclovir has been a frequently used antiviral agent in the clinical treatment of leukemia, acute encephalitis, malignant tumor and herpes simplex. The adverse effects of this drug have been widely described in clinical practice. In the present study, a case of a 35-year-old female patient diagnosed with herpes simple...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Cong Y,Teng Y

更新日期：2016-12-01 00:00:00

abstract：:The present study aimed to assess the usefulness of Dyna CT during transarterial uterine artery embolization (UAE) of fibroids. A total of 65 patients with symptomatic submucosal and intramural fibroids scheduled for transarterial UAE at the First People's Hospital of Changhou between May 2016 and September 2018 were ...

journal_title：Experimental and therapeutic medicine

authors： Wang CY,Xia JG,Chen WH,Lu YF,Han ZH,Wang Q

更新日期：2020-08-01 00:00:00

abstract：:The clinical effects were compared and analyzed of traditional Chinese medicine (TCM) 'Ling Gui Long Mu soup' combined with the conventional Western medications in treating child typhoid complicated by myocarditis. From July, 2010 to May, 2014, 54 children suffering from typhoid complicated by myocarditis were enrolle...

journal_title：Experimental and therapeutic medicine

authors： Tian J,An X,Fu M,Wang Q

更新日期：2016-12-01 00:00:00

abstract：:The aim of the present study was to evaluate the expression of vascular endothelial growth factor (VEGF) and hypoxia inducible factor-1 (HIF-1), and to investigate the role of the HIF-1/VEGF signaling pathway following spinal cord injury (SCI). A total of 90 12-week-old Sprague Dawley rats were randomly divided into t...

journal_title：Experimental and therapeutic medicine

authors： Chen H,Li J,Liang S,Lin B,Peng Q,Zhao P,Cui J,Rao Y

更新日期：2017-03-01 00:00:00

abstract：:Uterine leiomyoma is the most common benign tumor type of the female reproductive tract. Despite its high prevalence, the exact pathogenesis of the benign tumor remains unknown. In the present study, the effects of di-(2-ethylhexyl) phthalate (DEHP) on the proliferation and apoptosis rates and expression of inflammato...

journal_title：Experimental and therapeutic medicine

authors： Kim JH

更新日期：2018-06-01 00:00:00

abstract：:In a previous study by our group, Ajuga decumbens extract (ADE) was demonstrated to decrease the number of osteoclasts in subchondral bone and to have a synergistic effect with glucosamine in improving cartilaginous injuries in a rabbit model of osteoarthritis. In the present study, a concentrate of the useful fractio...

journal_title：Experimental and therapeutic medicine

authors： Sawada Y,Sugimoto A,Osaki T,Okamoto Y

更新日期：2018-05-01 00:00:00

abstract：:Collecting duct carcinoma (CDC), which is also known as Bellini duct carcinoma, accounts for less than 1% of all renal cell carcinoma, which has a poor prognosis. Predominantly, clinicians recognize this disease due to past experience and case reports, and a standard treatment is yet to be established. The present cas...

journal_title：Experimental and therapeutic medicine

authors： Zhu L,Wang Z,Pan C,Peng R,Wei X,Zhong Z

更新日期：2016-08-01 00:00:00

abstract：:The aim of the present study was to investigate the role of homocysteine (Hcy) in the pathogenesis of pulmonary embolism (PE) and the associated molecular mechanisms in human umbilical vein endothelial cells (HUVECs). Hcy contents were detected with high-performance liquid chromatography. Apoptosis was detected by flo...

journal_title：Experimental and therapeutic medicine

authors： Yang F,Qi X,Gao Z,Yang X,Zheng X,Duan C,Zheng J

更新日期：2016-10-01 00:00:00

abstract：:The aim of this study was to determine whether the vascular endothelial growth factor (VEGF) +936C/T polymorphism confers susceptibility to gastric cancer (GC) by conducting a meta-analysis. Publications addressing the association between the VEGF +936C/T polymorphism and GC risk were selected from the Pubmed, Embase ...

journal_title：Experimental and therapeutic medicine

authors： Zhou LP,Luan H,Dong XH,Jin GJ,Man DL,Shang H

更新日期：2011-09-01 00:00:00

abstract：:Gastrointestinal (GI) mucormycosis is a rare and life-threatening invasive fungal infection. GI mucormycosis occur in all parts of the alimentary tract, with the stomach being the most common site. Diabetes mellitus and other types of conditions associated with immunodeficiency, including hematologic malignancies, sol...

journal_title：Experimental and therapeutic medicine

authors： Lee SH,Son YG,Sohn SS,Ryu SW

更新日期：2014-08-01 00:00:00

abstract：:The aim of the present study was to investigate the electrophysiological properties of transient receptor potential melastatin 7 (TRPM7) channels in the cell membranes of cardiac fibroblasts (CFs). CFs obtained from Sprague-Dawley rats were treated with six different concentrations of angiotensin (Ang) II for 12 h. Th...

journal_title：Experimental and therapeutic medicine

authors： Zhou Y,Yi X,Wang T,Li M

更新日期：2015-05-01 00:00:00

abstract：:Avicularin (AL), quercetin-3-α-L-arabinofuranoside, has various pharmacological properties such as anticancer and anti-infective effects. However, the potential molecular mechanism via which AL exerts its anticancer activity is not fully understood. Cutaneous squamous cell carcinoma (CSCC) is the second most common sk...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Liu M,Chen S,Wu Q

更新日期：2020-02-01 00:00:00

abstract：:Transmembrane protein 174 (TMEM174) is a type III transmembrane protein with no clear signal peptide. The N and C terminals are located inside the cell. Our previous study demonstrated high expression of TMEM174 in the kidney and its potential involvement in renal cancer based on its capacity to stimulate cell prolife...

journal_title：Experimental and therapeutic medicine

authors： Hu F,Meng Y,Gou L,Zhang X

更新日期：2013-11-01 00:00:00

abstract：:Stress-related mucosal disease (SRMD) is a common complication in patients in the intensive care unit (ICU). The aim of the present study was to investigate the possible mechanisms for the pathogenesis of SRMD. In total, 38 patients with SRMD were enrolled from an ICU, as well as 15 healthy volunteers. The disease sev...

journal_title：Experimental and therapeutic medicine

authors： Wang X,Zhao Q,Shi H,Qi F,Shi N,Bai D,Li X,Yuan H,Zuo X

更新日期：2020-11-01 00:00:00

abstract：:Malignant melanoma is the most aggressive neoplasm, with severe metastatic potential. microRNAs represent a class of endogenously expressed, small non-coding RNAs that regulate gene expression. As a consequence, the translation of these mRNAs is inhibited or they are destabilized resulting in downregulation of the enc...

journal_title：Experimental and therapeutic medicine

authors： Yamazaki H,Chijiwa T,Inoue Y,Abe Y,Suemizu H,Kawai K,Wakui M,Furukawa D,Mukai M,Kuwao S,Saegusa M,Nakamura M

更新日期：2012-05-01 00:00:00

abstract：:Effects of antithrombotic agents on the bleeding risk after transurethral resection of the prostate (TURP) were assessed in patients with benign prostatic hyperplasia (BPH). Controlled clinical trials on the effects of perioperative anticoagulant therapy on postoperative bleeding in BPH patients published during Janua...

journal_title：Experimental and therapeutic medicine

authors： He Q,Yu Y,Gao F

更新日期：2020-10-01 00:00:00

abstract：:The aim of the present study was to investigate the expression levels of estrogen receptor (ER) α and β and human epidermal growth factor receptor-2 (Her-2), as well as the distribution of breast cancer molecular subtypes in Uygur and Han breast cancer patients. Cancer tissues were collected and analyzed from 709 brea...

journal_title：Experimental and therapeutic medicine

authors： Guo L,Hou X,Dilimina Y,Wang B

更新日期：2014-05-01 00:00:00

abstract：:The aim of the present study was to examine the effects of phacoemulsification and intraocular lens implantation combined with ciliarotomy in the treatment of angle-closure glaucoma with cataract in the elderly. A total of 68 patients were consecutively selected and divided into the control group with 33 cases (48 eye...

journal_title：Experimental and therapeutic medicine

authors： Li B,Wang FY,Lv TL,Zhu Y

更新日期：2016-10-01 00:00:00

abstract：:Valvular heart disease (VHD) is caused by either damage or defect in one of the four heart valves, aortic, mitral, tricuspid or pulmonary. Defects in these valves can be congenital or acquired. Age, gender, tobacco use, hypercholesterolemia, hypertension, and type II diabetes contribute to the risk of disease. VHD is ...

journal_title：Experimental and therapeutic medicine

authors： Zeng YI,Sun R,Li X,Liu M,Chen S,Zhang P

更新日期：2016-04-01 00:00:00

abstract：:The present study was designed to evaluate the anti-fatigue activity and the behavioral and biochemical effects of Kai-Xin-San (KXS) extracts on fatigued rats. The rats were randomly divided into six groups: untreated control (UC), running control (RC), RC treated with 13 mg/kg/day modafinil and RC treated with KXS at...

journal_title：Experimental and therapeutic medicine

authors： Hu Y,Cao Y,Liu M,Liu P,Cui H,Dai-Hong G

更新日期：2013-10-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection is the most common congenital infection worldwide, and remains a significant cause of the neurological deficiency and sensory deafness in developed countries. Maternal primary infection, reactivation or reinfection during pregnancy may lead to fetal infection and congenital CMV syndrome...

journal_title：Experimental and therapeutic medicine

authors： Gorun F,Motoi S,Malita D,Navolan DB,Nemescu D,Olariu TR,Craina M,Vilibic-Cavlek T,Ciohat I,Boda D,Dobrescu A

更新日期：2020-09-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) serve important roles in colorectal cancer. The aim of the present study was to investigate the expression and role of cervical carcinoma expressed PCNA regulatory (CCEPR) lncRNA in colorectal cancer progression. The results demonstrated that CCEPR expression was significantly higher in ...

journal_title：Experimental and therapeutic medicine

authors： Duan Y,Fang Z,Shi Z,Zhang L

更新日期：2019-11-01 00:00:00

abstract：:It is occasionally observed that patients without contrast-induced nephropathy (CIN) develop kidney injury within 1-6 months after coronary angiography (CAG), termed delayed CIN or delayed kidney injury (DKI) following CAG. The present study aimed to investigate the associated risk factors of delayed CIN and its possi...

journal_title：Experimental and therapeutic medicine

authors： Wang F,Peng C,Zhang G,Zhao Q,Xuan C,Wei M,Wang N

更新日期：2016-07-01 00:00:00

abstract：:The aim of the present investigation was to compare the effects of cyclic compression, perfusion, dexamethasone (DEX) and bone morphogenetic protein-7 (BMP-7) on the proliferation and differentiation of human bone marrow stromal cells (hBMSCs) in polyurethane scaffolds in a perfusion bioreactor. Polyurethane scaffolds...

journal_title：Experimental and therapeutic medicine

authors： Teng S,Liu C,Guenther D,Omar M,Neunaber C,Krettek C,Jagodzinski M

更新日期：2016-06-01 00:00:00

abstract：:The Global Registry of Acute Coronary Events (GRACE) risk score and the mean platelet volume to lymphocyte count ratio (MPVLR) can be used independently to predict adverse outcomes in patients with acute coronary syndromes. However, the level of MPVLR in relation to the GRACE score, and whether a combination of these ...

journal_title：Experimental and therapeutic medicine

authors： Chen X,Shao M,Zhang T,Zhang W,Meng Y,Zhang H,Hai H,Li G

更新日期：2020-06-01 00:00:00