Isolation of a tyrosinase inhibitor from unripe grapes juice: A spectrophotometric study.

Abstract:

:Grapes are known to contain high quantity of polyphenolic compounds, including caffeic, coumaric and ferulic acids esterified with tartaric acid, to yield caftaric, coutaric and fertaric acids, respectively. These acids are more abundant in unripe grapes, which can be processed into verjuice, a product that shows intrinsic resistance against microbial growth and significant antioxidant activity. In the present work, the isolation of hydroxycinnamoyl tartaric acids from unripe grape juice by chromatographic techniques was described. Moreover, the capability of caftaric acid to inhibit tyrosinase activity was evaluated by spectrophotometric assays. According to the kinetics parameters calculated, caftaric acid was shown to be a competitive inhibitor of tyrosinase, more potent than the related caffeic and chlorogenic acids, suggesting that it can be used in cosmetic and food industries for the development of natural skin whitening formulations and as an agent able to counteract the enzymatic browning of food.

journal_name

Food Chem

journal_title

Food chemistry

authors

Honisch C,Osto A,Dupas de Matos A,Vincenzi S,Ruzza P

doi

10.1016/j.foodchem.2019.125506

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

125506

eissn

0308-8146

issn

1873-7072

pii

S0308-8146(19)31624-3

journal_volume

305

pub_type

杂志文章