Abstract：
:The impact of oil type and fatty acid chain length on the development of food-grade microemulsions for the entrapment of β-carotene was investigated. The microemulsion region of a ternary phase diagram containing short chain monoglycerides was larger than for di- and triglycerides when Tween 80 was used as surfactant. The cytotoxicity of microemulsions composed of a 30% monoglyceride oil, 20% Tween 80 and 50% aqueous buffer were evaluated using an in vitro cell culture model (human epithelial colorectal adenocarcinoma, Caco-2). The cytotoxicity test showed that the viability of Caco-2 cells against β-carotene microemulsions at concentrations of 0.03125% (v/v) was higher than 90%. This study suggests that short chain monoglycerides could be used with Tween 80 to prepare transparent β-carotene-encapsulated O/W microemulsions in the particle size range of 12-100 nm.
journal_name
Food Chemjournal_title
Food chemistryauthors
Roohinejad S,Oey I,Wen J,Lee SJ,Everett DW,Burritt DJdoi
10.1016/j.foodchem.2014.11.056subject
Has Abstractpub_date
2015-05-01 00:00:00pages
270-8eissn
0308-8146issn
1873-7072pii
S0308-8146(14)01785-3journal_volume
174pub_type
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