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Simulating the Monty Hall problem in a DNA sequencing machine.

Abstract：

:The Monty Hall problem is a decision problem with an answer that is surprisingly counter-intuitive yet provably correct. Here we simulate and prove this decision in a high-throughput DNA sequencing machine, using a simple encoding. All possible scenarios are represented by DNA oligonucleotides, and gameplay decisions are implemented by sequencing these oligonucleotides from specific positions, with a single run simulating more than 12,000,000 independent games. This work highlights high-throughput DNA sequencing as a new tool that could extend existing capabilities and enable new encoding schemes for problems in DNA computing.

journal_name

Comput Biol Chem

journal_title

Computational biology and chemistry

authors

Mamet N,Harari G,Zamir A,Bachelet I

doi

10.1016/j.compbiolchem.2019.107122

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

107122

eissn

1476-9271

issn

1476-928X

pii

S1476-9271(19)30288-9

journal_volume

83

pub_type

杂志文章

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