Abstract:
:The authors are sorry to report that some of the HPLC data reported in their recently published paper [...].
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Chen CC,Nien CJ,Chen LG,Huang KY,Chang WJ,Huang HMdoi
10.3390/ijms20174178subject
Has Abstractpub_date
2019-08-26 00:00:00issue
17issn
1422-0067pii
ijms20174178journal_volume
20pub_type
已发布勘误abstract::Self-assembling peptides have been employed as biotemplates for biomineralization, as the morphologies and sizes of the inorganic materials can be easily controlled. We synthesized two types of highly ordered self-assembling peptides with different secondary structures and investigated the effects of secondary structu...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20184650
更新日期:2019-09-19 00:00:00
abstract::Molecular testing offers more objective information in the diagnosis and personalized decision making for thyroid nodules. In Korea, as the BRAF V600E mutation is detected in 70-80% of thyroid cancer specimens, its testing in fine-needle aspiration (FNA) cytology specimens alone has been used for the differential diag...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21165629
更新日期:2020-08-06 00:00:00
abstract::Previously, we developed a novel microRNA (miRNA) delivery system based on bacteriophage MS2 virus-like particles (MS2 VLPs). In this current study, we used this system to transport miR-146a into human peripheral blood mononuclear cells (PBMCs), and demonstrated the inhibition of osteoclastogenesis in precursors. Two ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms16048337
更新日期:2015-04-14 00:00:00
abstract::This study investigated the interaction between eupatorin and bovine serum albumin (BSA) using ultraviolet-visible (UV-vis) absorption, fluorescence, synchronous fluorescence, circular dichroism (CD) spectroscopies, and molecular modeling at pH 7.4. Results of UV-vis and fluorescence spectroscopies illustrated that BS...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms140714185
更新日期:2013-07-09 00:00:00
abstract::In order to understand the pyrolysis mechanism of β-O-4 type lignin dimers, a pyrolysis model is proposed which considers the effects of functional groups (hydroxyl, hydroxymethyl and methoxyl) on the alkyl side chain and aromatic ring. Furthermore, five specific β-O-4 type lignin dimer model compounds are selected to...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms18112364
更新日期:2017-11-09 00:00:00
abstract::Osteoarthritis (OA) remains one of the common degenerative joint diseases and a major cause of pain and disability in older adult individuals. Oral administration of non-steroidal anti-inflammatory drugs (NSAIDs) (such as diclofenac, DIC) or intra-articular injected gluco-corticosteroids (such as dexamethasone, DEX) w...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms22020665
更新日期:2021-01-11 00:00:00
abstract::Friedreich's ataxia (FA) is a trinucleotide repeats expansion neurodegenerative disorder, for which no cure or approved therapies are present. In most cases, GAA trinucleotide repetitions in the first intron of the FXN gene are the genetic trigger of FA, determining a strong reduction of frataxin, a mitochondrial prot...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21030916
更新日期:2020-01-30 00:00:00
abstract::Many studies have provided evidence suggesting that caspases not only contribute to the neurodegeneration associated with Alzheimer's disease (AD) but also play essential roles in promoting the underlying pathology of this disease. Studies regarding the caspase inhibition draw researchers' attention through time due t...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20194850
更新日期:2019-09-29 00:00:00
abstract::Over the years, anthropogenic factors have led to cadmium (Cd) accumulation in the environment causing various health problems in humans. Although Cd is not a Fenton-like metal, it induces oxidative stress in various animal models via indirect mechanisms. The degree of Cd-induced oxidative stress depends on the dose, ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms14036116
更新日期:2013-03-18 00:00:00
abstract:BACKGROUND:EphrinA1-Fc abolishes acute I/R injury and attenuates nonreperfused cardiac injury 4 days after permanent occlusion in mice. The goal of this study was to assess the capacity of a single intramyocardial administration of ephrinA1-Fc at the time of coronary artery ligation, to determine the degree to which ea...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21165811
更新日期:2020-08-13 00:00:00
abstract::The S-Allyl-L-cysteine (SAC) component of aged garlic extract (AGE) is proven to have anticancer, antihepatotoxic, neuroprotective and neurotrophic properties. -Cystathionase (CTH), cystathionine β-synthase (CBS) and 3-mercaptopyruvate sulfurtransferase (MPST) are involved in H2S/sulfane sulfur endogenous formation ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21031090
更新日期:2020-02-06 00:00:00
abstract::A conformational analysis of nine macrocyclic thioether musks has been carried out using molecular mechanics (MMFF), density functional theory (DFT) using both B3LYP and M06 functionals, as well as Hartree-Fock and post-Hartree-Fock (MP2) ab initio methods. 6-Thia-, 10-thia- and 4-methyl-5-thia-14-tetradecananolide, 4...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms10083488
更新日期:2009-08-04 00:00:00
abstract::The mechanism of the chemical reaction of H2O with three stabilized Criegee intermediates (stabCI-OO, stabCI-CH3-OO and stabCIx-OO) produced via the limonene ozonolysis reaction has been investigated using ab initio and DFT (Density Functional Theory) methods. It has been shown that the formation of the hydrogen-bonde...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms14035784
更新日期:2013-03-12 00:00:00
abstract::The current study examined the efficacy of royal jelly (RJ) against cadmium chloride (CdCl₂)-induced testicular dysfunction. A total of 28 Swiss male mice were allocated into four groups (n = 7), and are listed as follows: (1) the control group, who was intraperitoneally injected with physiological saline (0.9% NaCl) ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms19123979
更新日期:2018-12-10 00:00:00
abstract::Environmental issues pose huge threats to public health, particularly the damage caused by fine particulate matter (PM2.5). However, the mechanisms of injury require further investigation and medical materials that can protect the lungs from PM2.5 are needed. We have found that Colla corii asini, a traditional Chinese...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20010055
更新日期:2018-12-23 00:00:00
abstract::Chemosensitivity is a crucial feature for all tumours so that they can be successfully treated, but the huge heterogeneity of these diseases, to be intended both inter- and intra-tumour, makes it a hard-to-win battle. Indeed, this genotypic and phenotypic variety, together with the adaptability of tumours, results in ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms20071776
更新日期:2019-04-10 00:00:00
abstract::Zebrafish is a well-recognized organism for investigating vertebrate development and human diseases. However, the data on zebrafish proteome are scarce, particularly during embryogenesis. This is mostly due to the overwhelming abundance of egg yolk proteins, which tend to mask the detectable presence of less abundant ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20246359
更新日期:2019-12-17 00:00:00
abstract::The design, construction and initial tests on a combined laser light scattering and synchrotron X-ray scattering instrument can cover studies of length scales from atomic sizes in Angstroms to microns and dynamics from microseconds to seconds are presented. In addition to static light scattering (SLS), dynamic light s...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms160510016
更新日期:2015-05-04 00:00:00
abstract::Muscle contraction is initiated by the interaction between actin and myosin filaments. The sliding of actin filaments relative to myosin filaments is produced by cross-bridge cycling, which is governed by the theoretical framework of the cross-bridge theory. The cross-bridge theory explains well a number of mechanical...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms20215479
更新日期:2019-11-04 00:00:00
abstract::Obesity is a multifaceted pathophysiological condition that has been associated with lipid accumulation, adipocyte dysfunction, impaired mitochondrial biogenesis and an altered metabolic profile. Redox imbalance and excessive release of inflammatory mediators have been intricately linked in obesity-associated phenotyp...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21010087
更新日期:2019-12-21 00:00:00
abstract::A new approach for encoding DNA sequences as input for DNA sequence analysis is proposed using the error correction coding theory of communication engineering. The encoder was designed as a convolutional code model whose generator matrix is designed based on the degeneracy of codons, with a codon treated in the model ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms14048393
更新日期:2013-04-16 00:00:00
abstract::The protective effect of sesamin (SES) from sesame meal on NIT-1 pancreatic β-cells damaged by streptozotocin (STZ) in vitro was investigated. The cell viability, insulin secretion, the activity of superoxide dismutase(SOD), glutathione peroxidase (GSHpx) and the content of reduced glutathione (GSH) increased signific...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms131216961
更新日期:2012-12-11 00:00:00
abstract::The ATP-sensitive K+ channel (KATP) is involved in hypersensitivity during chronic pain and is presumed to be a downstream target of mu opioid receptors. Multiple subtypes of KATP channels exist in the peripheral and central nervous system and their activity may be inversely correlated to chronic pain phenotypes in ro...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20092251
更新日期:2019-05-07 00:00:00
abstract::Modern strategies in adipose tissue engineering (ATE) take advantage of the easy harvest, abundance and differentiation potential towards mesenchymal lineages of hADSCs. The controlled conversion of hADSCs to committed adipogenic precursors and further mature adipocytes formation is important for good long-term result...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms131215881
更新日期:2012-11-27 00:00:00
abstract::The iliotibial band (ITB) is a suitable scaffold for anterior cruciate ligament (ACL) reconstruction, providing a sufficient mechanical resistance to loading. Hence, ITB-derived fibroblasts attract interest for ligament tissue engineering but have so far not been characterized. This present study aimed at characterizi...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20081972
更新日期:2019-04-22 00:00:00
abstract::Recent studies have identified cyclic GMP-AMP synthase (cGAS) as an important target for treating autoimmune diseases, and several inhibitors of human cGAS (hcGAS) and their structures in complexation with hcGAS have been reported. However, the mechanisms via which these inhibitors interact with hcGAS are not complete...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms22031164
更新日期:2021-01-25 00:00:00
abstract::Lipid peroxidation products, such as 7-ketocholesterol (7KC), may be increased in the body fluids and tissues of patients with neurodegenerative diseases and trigger microglial dysfunction involved in neurodegeneration. It is therefore important to identify synthetic and natural molecules able to impair the toxic effe...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms17121973
更新日期:2016-11-25 00:00:00
abstract::We first demonstrated that long-term increased polyamine (spermine, spermidine, putrescine) intake elevated blood spermine levels in mice and humans, and lifelong consumption of polyamine-rich chow inhibited aging-associated increase in aberrant DNA methylation, inhibited aging-associated pathological changes, and ext...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms20051254
更新日期:2019-03-12 00:00:00
abstract::Homologous recombination (HR) is often used to achieve targeted gene integration because of its higher precision and operability compared with microhomology-mediated end-joining (MMEJ) or non-homologous end-joining (NHEJ). It appears to be inefficient for gene integration in animal cells and embryos due to occurring o...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms21165821
更新日期:2020-08-13 00:00:00
abstract::The success of antibody therapeutics is strongly influenced by their multifunctional nature that couples antigen recognition mediated by their variable regions with effector functions and half-life extension mediated by a subset of their constant regions. Nevertheless, the monospecific IgG format is not optimal for ma...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21207496
更新日期:2020-10-12 00:00:00