Abstract:
BACKGROUND:Current evidence concerning the association between persistent organic pollutants (POPs) and polycystic ovary syndrome (PCOS) is inconsistent. The aim of the present systematic review and meta-analysis is to evaluate the role of POPs in PCOS. METHODS:Databases including PubMed, Embase, Web of Science, and CNKI will be searched to identify qualified studies. All qualified studies regarding the association between POPs and PCOS will be included. The primary outcome of the present study is POPs levels in serum of subjects. Pooled analysis with corresponding 95% confidence intervals will be performed. RESULTS:The comprehensive analysis and quantitative assessment will provide a better understanding of POPs concentrations in patients with PCOS. CONCLUSION:This meta-analysis and systematic review will generate evidence of the association between POPs and PCOS. PROSPERO REGISTRATION NUMBER:PROSPERO CRD42019126373.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Li Y,Zhang MW,Wang YJdoi
10.1097/MD.0000000000016948subject
Has Abstractpub_date
2019-08-01 00:00:00pages
e16948issue
34eissn
0025-7974issn
1536-5964pii
00005792-201908230-00056journal_volume
98pub_type
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