Abstract:
:To investigate the clinical efficiency of periocular triamcinolone acetonide (TA) injection for treating polypoidal choroidal vasculopathy (PCV) concurrent with hemorrhagic retinal detachment (HRD).Twenty-two cases confirmed with PCV concurrent with HRD characterized by massive subretinal hemorrhage and exudation presented to our department from January 2015 to May 2017 were included in this study. The initial vision varied from counting finger to 0.2. All cases were randomly divided into TA group (n = 12), which received periocular TA injection per month, and anti-VEGF group (n = 10), which were treated by anti-VEGF intravitreous injection per month. The patients were followed up for 6 months, in which fundus examination and visual acuity along with optical coherence tomography (OCT) were carried out.The treatment effect is divided into the following categories. Cure was defined as the elimination of subretinal hemorrhage and exudation accompanied by retinal edema and choroidal neovascularization (CNV) extinction and rise of visual acuity. Improvement was characterized by alleviation of subretinal hemorrhage and exudation accompanied by retinal edema and CNV reduction and rise of visual acuity. Ineffective means remained subretinal hemorrhage and exudation in fundus and no improvement of visual acuity, and polypoid lesions in OCT images. Among the 12 cases in TA group, 1 case was treated by periocular injection of TA twice, and 11 cases were treated by 3 times injection. After that, 3 cases (25%) were cured, 8 cases (66.7%) got improvement, and only 1 case (8.3%) showed no response. Although among 10 cases in the anti-VEGF group, 3 cases were treated by anti-VEGF intravitreous injection twice. Seven cases were treated by 3 times injection. After that, 4 cases (40%) got improvement, and the other 6 case (60%) showed no response. All patients showed no recurrence in the 6-month follow-up. No complications were noticed under periocular injection or intravitreous injection.Periocular TA injection is effective for treating PCV concurrent with HRD.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Zhang K,Chen Y,Sun X,Zhong Q,Lin L,Gao Y,Hong Fdoi
10.1097/MD.0000000000012464subject
Has Abstractpub_date
2018-09-01 00:00:00pages
e12464issue
39eissn
0025-7974issn
1536-5964pii
00005792-201809280-00052journal_volume
97pub_type
杂志文章相关文献
MEDICINE文献大全abstract:OBJECTIVE:We aimed to investigate the value of the combined use of high-resolution ultrasound thyroid imaging reporting and data system (TI-RADS) classification and thyroid fine needle aspiration cytology (Bethesda classification) for the qualitative diagnosis of benign and malignant thyroid nodules. METHODS:We enroll...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000018320
更新日期:2019-12-01 00:00:00
abstract::This study investigated the possible relationship between endocarditis and overall and individual cancer risk among study participants in Taiwan.We used data from the National Health Insurance program of Taiwan to conduct a population-based, observational, and retrospective cohort study. The case group consisted of 14...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003198
更新日期:2016-03-01 00:00:00
abstract:RATIONALE:Communicating bronchopulmonary foregut malformation (CBPFM) is a rare congenital malformation involving both the digestive and respiratory systems. To our best knowledge, most cases of CBPFM reported in the literature were in infancy or adulthood and CBPFM in infantile is even rarer with a high case-fatality ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006307
更新日期:2017-03-01 00:00:00
abstract::The impact of a publication in a particular medical area is reflected by the number of times the article is included as a citation. It is not known, however, which articles are cited the most in primary care journals. In our study, we aimed to identify the 100 most cited articles in primary care medicine and analyze t...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002219
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Currently, there is some clinical evidence supporting the use of acupuncture in alleviating pain and dysfunction in patients with lumbar spinal stenosis (LSS). However, the question of whether acupuncture could be efficacious for ageing patients remains unanswered. We designed a randomized controlled study t...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000021444
更新日期:2020-07-31 00:00:00
abstract:INTRODUCTION:Duodenal obstructions caused by congenital anatomic abnormalities are rare in adults. Several patients in whom the duodenal obstruction was caused by a congenital duodenal diaphragm have been described. The duodenal obstruction in the patient presented herein was caused by a transverse septum, which has no...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007093
更新日期:2017-10-01 00:00:00
abstract::This study was conducted to investigate the clinicopathological features of synchronous cancers and treatment options according to their locations.Records of 8368 patients with colorectal cancer treated at our center between July 2003 and December 2010 were analyzed retrospectively. All synchronous colorectal cancer p...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006224
更新日期:2017-03-01 00:00:00
abstract::Lung ultrasound (LU) is increasingly used to assess pleural and lung disease in intensive care unit (ICU) and emergency unit at the bedside. We assessed the performance of bedside chest radiograph (CR) and LU during severe acute chest syndrome (ACS), using computed tomography (CT) as the reference standard. We prospec...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002553
更新日期:2016-02-01 00:00:00
abstract::Lipoprotein-associated phospholipase A2 (Lp-PLA2) probably plays an important role in the development of acute coronary syndrome (ACS). However, alterations of Lp-PLA2 levels during ACS and its association with cardiovascular outcome are unclear. Our aim was to investigate the change in Lp-PLA2 and its association wit...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011517
更新日期:2018-07-01 00:00:00
abstract::Our previous study confirmed the negative association between the development of calcarine sulcus and the width of lateral ventricles. The purpose of current study was to evaluate the reliability of calcarine sulcus depth in the 2nd trimester to predict the prenatal enlargement of lateral ventricle in fetuses with iso...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007506
更新日期:2017-07-01 00:00:00
abstract::Assessment the prevalence of hypertension and its relation to selected indicators of health status and performance, including classification of BMI, obesity classifications, and body structure in a large test group of 19-year-old men.The study was observational-retrospective, and included a group of 17,282 men, aged 1...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020398
更新日期:2020-05-29 00:00:00
abstract::Acute care of stroke victims largely relies on the rapid identification and timely clinical and radiological assessment. We evaluated the effect of the number of patient companions on the efficiency of the diagnostic process in the emergency department (ED).Consecutive stroke patients admitted to the ED between August...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000520
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION:Lateral ligamentous complex injury without fracture or dislocation is rare in the literature. Due to the rare injury, it is not clear yet about the proper treatment. This case report suggests a specific diagnosis of this injury as well as an appropriate surgical method. PATIENT CONCERNS:In one-month perio...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017447
更新日期:2019-10-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000006423.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/MD.0000000000006811
更新日期:2017-04-28 00:00:00
abstract::By retrieving records from Taiwan's National Health Insurance (NHI) system's database, the current study aimed to investigate the impacts of hysterosalpingography (HSG) to patients after ectopic pregnancy (EP) operations in Taiwan.In this retrospective cohort study, insurance claims data from 1997 to 2013, derived fro...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007263
更新日期:2017-06-01 00:00:00
abstract::China has increasing incidence of unplanned pregnancies among college students these years. Increasing students' sense of responsibility to protect sexual partners may help reduce the rate of unplanned pregnancies.A self-administered questionnaire was distributed to students from 3 colleges in Sichuan, China. Among th...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013879
更新日期:2019-01-01 00:00:00
abstract::The objective to assess the association between gastrectomy and the risk of pulmonary tuberculosis among patients without gastric cancer in Taiwan.There were 762 subjects with newly performing gastrectomy as the gastrectomy group since 2000 to 2012, and 2963 randomly selected subjects without gastrectomy as the non-ga...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011388
更新日期:2018-07-01 00:00:00
abstract::The purpose of study was to analyze the participants' opinions concerning the effectiveness of 6 denture adhesives (DA). The study group included 60 participants. Criteria for selecting the patients were as follows: reduced retention and stabilization of maxillary complete dentures and xerostomia. These features were ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000545
更新日期:2015-02-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000004251.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/MD.0000000000005665
更新日期:2016-12-09 00:00:00
abstract:RATIONALE:Hypereosinophilic syndrome (HES) is a rare disease characterized by hypereosinophilia and its ensuing organ damage. Cardiac involvement is divided into 3 chronological stages: an acute necrotic stage; a thrombus formation stage; and a fibrotic stage. Infiltration of the myocardium by eosinophilic cells follow...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010079
更新日期:2018-03-01 00:00:00
abstract::Awake craniotomy is a unique technique utilized for mapping neuro and motor function during neurosurgical procedures close to eloquent brain tissue. Since active communication is required only during surgical manipulation of eloquent brain tissue and the patient is "sedated" during other parts of the procedure, differ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017473
更新日期:2019-10-01 00:00:00
abstract::Choice of surgical approach in patients under clopidogrel treatment is controversial. Intertrochanteric fractures are common in the elderly, who also suffer from a number of comorbidities.The aim of this study is to assess the prognosis of elderly patients with clopidogrel treatment after surgery for intertrochanteric...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008169
更新日期:2017-09-01 00:00:00
abstract::The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery (SYNTAX) score is an invasive coronary angiography (ICA)-based score for quantifying the complexity of coronary artery disease (CAD). Although the SYNTAX score was originally developed based on ICA, recent publications have reported ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007999
更新日期:2017-09-01 00:00:00
abstract::Clinical practice guidelines (CPGs) play an important role in health care. The guideline development process should be precise and rigorous to ensure that the results are reproducible and not vague. To determine the quality of guidelines, the Appraisal of Guidelines and Research and Evaluation (AGREE) instrument was d...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000635
更新日期:2015-03-01 00:00:00
abstract::Intussusception is common emergency condition in children. Pneumatic or hydrostatic reduction (HR) is considered the first-choice management strategy in cases lacking indications for surgical intervention. Generally, sedatives are not used in children undergoing interventional radiology procedures. Surgical management...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018956
更新日期:2020-01-01 00:00:00
abstract::Using nasopharyngeal carriage as a marker of vaccine impact, pneumococcal colonization and its relation to invasive disease were examined in children, their parents, and older adults in the United Kingdom following introduction of 7-valent pneumococcal conjugate vaccine (PCV7) and prior to 13-valent pneumococcal conju...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000335
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Acute chronic liver failure (ACLF) is the most common type of liver failure. The clinical symptoms are complex and changeable, the treatment is difficult and the fatality rate is high. It has become an urgent problem to actively seek effective treatment means and improve the clinical efficacy of ACLF patient...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022585
更新日期:2020-10-09 00:00:00
abstract:BACKGROUND:Patients with simple obesity suffer from poor quality of life, as well as high risk of hypertension, diabetes, cardiovascular, and cerebrovascular accidents. Lots of Clinical trials suggested that acupuncture is beneficial for simple obesity, and it aims to gather solid evidence in order to provide reliable ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017353
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:This study aims to systematically explore the effectiveness of neuromuscular electrical stimulation (NMES) combined with rehabilitation training (RT) for the treatment of post-stroke limb spasticity (PSLS). METHODS:We will search Cochrane Library, MEDILINE, EMBASE, CINAHL, AMED, PsycINFO, WOS, Scopus, OpenG...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017261
更新日期:2019-09-01 00:00:00
abstract:RATIONALE:Frontometaphyseal dysplasia (FMD) is a dominant X-linked rare disease caused by mutations of FLNA. The distinctive features of FMD include skeletal dysplasia, facial dysmorphism, extremities anomalies, deafness, cleft palate and eye anterior segment anomalies, yet none of the complications, such as acro-osteo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011283
更新日期:2018-07-01 00:00:00