Clinicopathological features and surgical options for synchronous colorectal cancer.

Abstract:

:This study was conducted to investigate the clinicopathological features of synchronous cancers and treatment options according to their locations.Records of 8368 patients with colorectal cancer treated at our center between July 2003 and December 2010 were analyzed retrospectively. All synchronous colorectal cancer patients who underwent surgical treatment were included.Synchronous cancers were identified in 217 patients (2.6%). Seventy-nine patients underwent either total colectomy, subtotal colectomy, or total proctocolectomy; 116 underwent 1 regional resection, including local excision; and 22 underwent 2 regional resections. The mean age was 62 years, slightly higher than that for the single-cancer patients. Synchronous cancers were more common in male patients, more frequently located in the left colon, had more microsatellite instability-high status, and showed more advanced stage than single cancer. Extensive resection was mainly performed for synchronous cancers located in both the right and left colon. Two regional resections were performed for cancers in the right colon and rectum. There were no differences in complication rates or the occurrence of metachronous cancer between the 2-region resection and extensive resection groups. Eight years postoperatively, the mean number of daily bowel movements for these 2 groups were 1.9 and 4.3, respectively.We found that synchronous cancer was different from single cancer in terms of age, gender, location, and pathologic features. Synchronous colorectal cancer requires different treatment strategy according to the distribution of lesions. Comparison between the 2 regional resections and extensive resection approaches suggests that 2 regional resections are preferable.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Lee BC,Yu CS,Kim J,Lee JL,Kim CW,Yoon YS,Park IJ,Lim SB,Kim JC

doi

10.1097/MD.0000000000006224

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

e6224

issue

9

eissn

0025-7974

issn

1536-5964

pii

00005792-201703030-00031

journal_volume

96

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Acupuncture on treating angina pectoris: A systematic review.

    abstract:BACKGROUND:Coronary heart disease angina pectoris is a common clinical symptom in patients with coronary heart disease, due to coronary atherosclerotic stenosis or sputum leading to coronary insufficiency, myocardial transient ischemia, hypoxia caused by precordial pain as the main clinical manifestations Group syndrom...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018548

    authors: Wang JS,Yu XD,Deng S,Yuan HW,Li HS

    更新日期:2020-01-01 00:00:00

  • Successful open reduction and internal fixation for displaced femoral fracture in a patient with osteopetrosis: Case report and lessons learned.

    abstract:RATIONALE:Osteopetrosis is a rare disease that predominantly occurs in descendants of inbreeding families. In the case of fractures happen in patients with osteopetrosis, the choice between operative or conservative treatment is still controversial. Open reduction and internal fixation (ORIF) is a conventional treatmen...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007777

    authors: Huang J,Pan J,Xu M,Xu S

    更新日期:2017-08-01 00:00:00

  • Uncommon cause of fungemia in a patient with renal cell cancer: A case report of Candida lusitaniae Fungemia.

    abstract:INTRODUCTION:We present an interesting case of Candida lusitaniae infection in a patient diagnosed with renal clear cell carcinoma.An 82-year-old male presented with worsening back pain for 1 week. Physical examination including neurologic examination was normal. A computed tomography scan of the abdomen revealed a mas...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008510

    authors: Mishra R,Kelly P,Toolsie O,Ayyadurai P,Adrish M

    更新日期:2017-11-01 00:00:00

  • Osteonecrosis of the femoral head, nonunion and potential risk factors in Pauwels grade-3 femoral neck fractures: A retrospective cohort study.

    abstract::The present study was to analyze clinical outcome of Pauwels grade-3 femoral neck fractures treated by different surgical techniques. Potential risk factors associated with nonunion and osteonecrosis of the femoral head (ONFH) were investigated as well. The retrospective study comprised of 67 sequential patients treat...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003706

    authors: Zhang YL,Chen S,Ai ZS,Gao YS,Mei J,Zhang CQ

    更新日期:2016-06-01 00:00:00

  • Nutritional therapy and effect assessment of infants with primary intestinal lymphangiectasia: Case reports.

    abstract:RATIONALE:Intestinal lymphangiectasia (IL) is a rare enteropathy involving the expansion and rupture of intestinal lymphatic channels. Although several reports have studied cases of primary IL (PIL), this condition is very rare, and is even less commonly encountered in infants. This study aimed to investigate the nutri...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009240

    authors: Li S,Liu X,He Y,Li Q,Ji L,Shen W,Tong G

    更新日期:2017-12-01 00:00:00

  • Reversible posterior leukoencephalopathy syndrome following apatinib for gastric cancer in an adult: A case report and a review of the literature.

    abstract:RATIONALE:Reversible posterior leukoencephalopathy syndrome (RPLS) is characterized by rapidly progressive hypertension, headache, and disturbance of consciousness. Moreover, RPLS is rarely reported after apatinib treatment. PATIENT CONCERNS:We present a case of RPLS induced by apatinib in this report. The patient had...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017787

    authors: Lv Y,Zhang Y,Zhang J,Liang N,Liu F,Liu R

    更新日期:2019-11-01 00:00:00

  • Assessment of the periodontal health status in patients undergoing orthodontic treatment with fixed appliances and Invisalign system: A meta-analysis.

    abstract:BACKGROUND:At present, many scholars have studied the periodontal health status of patients undergoing orthodontic treatment with fixed appliances and invisalign. However, those results are inconsistent. Therefore, we conducted this meta-analysis, and then provide reference for clinical treatment. METHODS:Most databas...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000010248

    authors: Lu H,Tang H,Zhou T,Kang N

    更新日期:2018-03-01 00:00:00

  • Assessment of left ventricular function in chronic alcoholics by real-time three-dimensional echocardiography.

    abstract::Chronic alcohol consumption may lead to progressive cardiac dysfunction. The aim of this study was to evaluate the feasibility of using real-time 3-dimensional echocardiography (3DE) on assessing left ventricular (LV) function in chronic alcoholics.We classified 92 male alcoholics into mild, moderate, and severe group...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006033

    authors: Wang Y,Shan G,Shen J,Zhou Q,Tan B,Liu Y,Luo R,Zhao S,Bi W,Yao F,Li G

    更新日期:2017-02-01 00:00:00

  • Radiofrequency ablation for lung squamous cell carcinoma in a single-lung patient: A case report and literature review.

    abstract:RATIONALE:High morbidity and high mortality are the main features of non-small cell lung cancer (NSCLC). Radiofrequency ablation, which produces a large amount of heat to kill tumor cells, is one effective way to treat this disease. PATIENT CONCERNS:We report the case of a 74-year-old man who presented with a 1-month ...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000015805

    authors: Song GQ,Li GG,Chen F,Chen DS,Qian HJ,Deng XE,Lu HQ,Lin B

    更新日期:2019-06-01 00:00:00

  • Isolated Langerhans cell histiocytosis of the spleen: A case report.

    abstract:RATIONALE:Langerhans cell histiocytosis (LCH) is a relatively rare disorder characterized by the proliferation of abnormal Langerhans cells. Splenic involvement usually presents in children with multisystem LCH, and isolated LCH of the spleen is a very rare disease. Herein, we report a case of isolated splenic LCH in a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012378

    authors: Hong L,Sun G,Peng L,Tu Y,Li Y,Xiao W

    更新日期:2018-09-01 00:00:00

  • Meta-analysis of efficacy and safety of custirsen in patients with metastatic castration-resistant prostate cancer.

    abstract::Custirsen is the second-generation antisense oligonucleotide (ASO), which can reduce cellular levels of clusterin to increase the cytotoxic effect of chemotherapeutic drugs. Our study assessed the efficacy and safety of custirsen in patients with metastatic castration-resistant prostate cancer (mCRPC).We conducted a c...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000014254

    authors: Zhang X,Liu C,Li K,Wang K,Zhang Q,Cui Y

    更新日期:2019-02-01 00:00:00

  • Diagnostic Value of Serum IgG4 for IgG4-Related Disease: A PRISMA-compliant Systematic Review and Meta-analysis.

    abstract::Many studies about serum IgG4 for the diagnosis of IgG4-related disease (IgG4-RD) have been reported. However, these studies had relatively small sample sizes and the diagnostic accuracy values varied much between them.The aim of this study was to perform a meta-analysis to evaluate the diagnostic value of serum IgG4 ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000003785

    authors: Hao M,Liu M,Fan G,Yang X,Li J

    更新日期:2016-05-01 00:00:00

  • Which neoadjuvant chemotherapy regimen should be recommended for patients with advanced nasopharyngeal carcinoma?: A network meta-analysis.

    abstract:BACKGROUND:The clinical application has widespread disagreement on the different regimens of neoadjuvant chemotherapy (NCT) in the treatment of locoregionally advanced nasopharyngeal carcinoma (NPC). We conducted a network meta-analysis (NMA) to evaluate the efficacy of the different NCT regimens in the treatment of NP...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000011978

    authors: Yuan C,Xu XH,Luo SW,Wang L,Sun M,Ni LH,Xu L,Wang XL,Zeng G

    更新日期:2018-08-01 00:00:00

  • Repeat microvascular decompression for patients with persistent or recurrent trigeminal neuralgia: Prognostic factors and long-term outcomes.

    abstract::Patients with persistent or recurrent trigeminal neuralgia (TN) after microvascular decompression (MVD) are frequently difficult to manage. This study aimed to analyze the safety and efficiency of repeat MVD, with the main focus on prognostic factors and long-term outcomes.We performed a retrospective study of 41 TN p...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015167

    authors: Cheng J,Meng J,Lei D,Hui X

    更新日期:2019-05-01 00:00:00

  • Association between the A46G polymorphism (rs1042713) in the β2-adrenergic receptor gene and essential hypertension susceptibility in the Chinese population: A PRISMA-compliant meta-analysis.

    abstract:BACKGROUND:Recently, many studies have been conducted to investigate the relationship between the A46G polymorphism in the β2-adrenergic receptor (ADRB2) gene and essential hypertension risk in the Chinese population. However, the results of previous studies were conflicting. OBJECTIVES:The present study aimed to inve...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000023164

    authors: Yan L,Wang H,Liu P,Wang M,Chen J,Zhao X

    更新日期:2020-11-13 00:00:00

  • Spinal epidural hematoma occurring at a distance from the transforaminal epidural injection site: A case report.

    abstract:RATIONALE:Transforaminal epidural steroid injection (TFESI) is a conservative method to treat back pain due to radiculopathy. However, epidural hematoma can occur after the procedure by various mechanisms, which can cause serious complications. PATIENT CONCERNS:An 82-year-old man with spinal stenosis was treated with ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016654

    authors: Kim SI,Lee DH,Kim SH,Cho YH

    更新日期:2019-07-01 00:00:00

  • Hepatic outflow obstruction (Budd-Chiari syndrome). Experience with 177 patients and a review of the literature.

    abstract::Budd-Chiari syndrome (BCS) may not be as uncommon as was once believed. Our study has substantiated the existence of 2 major clinical forms. The acute syndrome is invariably associated with extensive blockage of the major hepatic veins, resulting in congestive liver cell necrosis. In a small, but significant, number o...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00005792-199401000-00003

    authors: Dilawari JB,Bambery P,Chawla Y,Kaur U,Bhusnurmath SR,Malhotra HS,Sood GK,Mitra SK,Khanna SK,Walia BS

    更新日期:1994-01-01 00:00:00

  • Localized amyloidosis of the genitourinary tract: report of 5 new cases and review of the literature.

    abstract::Primary localized amyloidosis of the genitourinary tract is a rare entity characterized by small pseudotumors localized in the renal pelvis, ureters, or bladder. Amyloid fibrils are derived from immunoglobulin light chains, but no systemic plasma cell proliferation is detected. The clinical and radiologic features mim...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0b013e31821cbdab

    authors: Monge M,Chauveau D,Cordonnier C,Noël LH,Presne C,Makdassi R,Jauréguy M,Lecaque C,Renou M,Grünfeld JP,Choukroun G

    更新日期:2011-05-01 00:00:00

  • Mannitol-induced acute renal failure.

    abstract::Mannitol is widely used to reduce intracranial pressure and is protective against ischemic and nephrotoxic acute renal failure. However, the capacity of this seemingly innocuous agent to produce acute renal failure is not well recognized. We report herein the clinical course of 8 cases of mannitol-induced acute renal ...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00005792-199005000-00003

    authors: Dorman HR,Sondheimer JH,Cadnapaphornchai P

    更新日期:1990-05-01 00:00:00

  • The radiosensitive effect of apatinib for hepatocellular carcinoma patient with big paraspinal metastasis: A case report.

    abstract:RATIONALE:Hepatocellular carcinoma (HCC) is a highly invasive cancer associated with great mortality rates. The prognosis of advanced HCC is very poor. PATIENT CONCERNS:Here, we report a HCC patient with a big paraspinal metastasis with 10 cm in diameter who failed the treatment of sorafenib. DIAGNOSES:Sorafenib refr...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009598

    authors: Zhu H,Zhao Y,Wang X

    更新日期:2018-01-01 00:00:00

  • Placebo-Controlled Trials in Surgery: A Systematic Review and Meta-Analysis.

    abstract::This systematic review was performed to investigate the ethical justification, methodological quality, validity and safety of placebo controls in randomized placebo-controlled surgical trials.Central, MEDLINE, and EMBASE were systematically searched to identify randomized controlled trials comparing a surgical procedu...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000003516

    authors: Probst P,Grummich K,Harnoss JC,Hüttner FJ,Jensen K,Braun S,Kieser M,Ulrich A,Büchler MW,Diener MK

    更新日期:2016-04-01 00:00:00

  • The disadvantage of morning blood pressure management in hypertensive patients.

    abstract::To investigate whether the control of morning blood pressure (MBP) reflects the control of blood pressure (BP) in other periods (daytime, nighttime and 24-hour) and to assess whether morning BP displays a closer association with subclinical target organ damage (TOD) than the BP measured in other periods.One thousand o...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019278

    authors: Liu K,Xu Y,Gong S,Li J,Li X,Ye R,Liao H,Chen X

    更新日期:2020-02-01 00:00:00

  • Case Report: Bazex Syndrome Associated With Pulmonary Adenocarcinoma.

    abstract::Bazex syndrome, a rare paraneoplastic syndrome characterized by psoriasiform eruptions, palmoplantar keratosis, and symmetric onychodystrophy, is most prevalent with squamous cell carcinomas of the upper aerodigestive tract.Here, we reported an uncommon case of Bazex syndrome about an 83-year-old man with pulmonary ad...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002415

    authors: Zhao J,Zhang X,Chen Z,Wu JH

    更新日期:2016-01-01 00:00:00

  • Evaluation of multiple screening methods for cervical cancers in rural areas of Xinjiang, China.

    abstract::This study is to evaluate the screening methods of cervical cancers for rural females in Kash bachu, Xinjiang, China.A total number of 3000 married females were surveyed, and subjected to the gynecological examination. In these subjects, 1993 females received the careHPV (human papillomavirus) test, while 1007 females...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019135

    authors: Naizhaer G,Yuan J,Mijiti P,Aierken K,Abulizi G,Qiao Y

    更新日期:2020-02-01 00:00:00

  • Successful management of a complicated clinical crisis: A patient with left-sided endocarditis and secondary hemophagocytic lymphohistiocytosis: a rare case report and literature review.

    abstract:RATIONALE:Hemophagocytic lymphohistiocytosis (HLH) secondary to methicillin-resistant Staphylococcus epidermidis (MRSE)-related left-sided infectious endocarditis had never been reported before. In the last decade, daptomycin, a novel lipopeptide antibiotic, showed its excellent role in anti-Gram-positive bacteria, inc...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000009451

    authors: Xu P,Zeng H,Zhou M,Ouyang J,Chen B,Zhang Q

    更新日期:2017-12-01 00:00:00

  • Use of the SYNTAX Score II to predict mortality in interventional cardiology: A systematic review and meta-analysis.

    abstract:BACKGROUND:As the SYNTAX Score has limitations, it should be replaced by another better angiographic tool. By comparing mortality that was observed following percutaneous coronary intervention (PCI) in patients who were allotted a low versus a high score, we aimed to systematically investigate mortality prediction usin...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000014043

    authors: Yang H,Zhang L,Xu CH

    更新日期:2019-01-01 00:00:00

  • Asymmetric limb lengthening in the treatment of tibial hemimelia caused by osteomyelitis: A case report.

    abstract:RATIONALE:Tibial hemimelia is known as a rare congenital lower limb deficiency. It has been classified into different types based on Jones classification, and the traditional treatment of tibial hemimelia is amputation. Here we present a variant and unclassified case of tibial hemimelia, which was caused by osteomyelit...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014031

    authors: Yu L,Yu G,Deng K,Wang G

    更新日期:2019-01-01 00:00:00

  • Surgery combined with radio-chemotherapy for esophageal mucoepidermoid carcinoma: A case report.

    abstract:RATIONALE:Primary mucoepidermoid carcinoma (MEC) of the esophagus is a rare type of malignant neoplasm. Its morphology resembles that of MEC of the salivary glands. It is characterized by a diffuse mixture of squamous and mucus-secreting glandular carcinoma cells. Due to the low incidence of esophageal MEC, the biologi...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011165

    authors: Zheng C,Chen X,Zhang F,Yan L,Zhang X

    更新日期:2018-06-01 00:00:00

  • Response to immune complex vaccine in chronic hepatitis B patients is associated with lower baseline level of serum IgG galactosylation.

    abstract::The composition of glycan in immunoglobulin G (IgG) has shown to affect various diseases and can be regulated by drugs and preventive vaccination. A hepatitis B surface antigen (HBsAg)-hepatitis B immunoglobulin (HBIG) immune complex (YIC) therapeutic vaccine for chronic hepatitis B (CHB) patients has undergone clinic...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000016208

    authors: Han J,Gong GZ,Lei JH,Qin WJ,Qin RH,Wang XY,Gu JX,Ren SF,Wen YM

    更新日期:2019-06-01 00:00:00

  • Multiple Genetic Analysis System-Based Antibiotic Susceptibility Testing in Helicobacter pylori and High Eradication Rate With Phenotypic Resistance-Guided Quadruple Therapy.

    abstract::Antibiotics resistance in Helicobacter pylori (H. pylori) is the major factor for eradication failure. Molecular tests including fluorescence in situ hybridization, PCR-restriction fragment length polymorphism, and dual priming oligonucleotide-PCR (DPO-PCR) play critical roles in the detection of antibiotic susceptibi...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000002056

    authors: Dong F,Ji D,Huang R,Zhang F,Huang Y,Xiang P,Kong M,Nan L,Zeng X,Wu Y,Bao Z

    更新日期:2015-11-01 00:00:00