Abstract:
:Clinical practice guidelines (CPGs) play an important role in health care. The guideline development process should be precise and rigorous to ensure that the results are reproducible and not vague. To determine the quality of guidelines, the Appraisal of Guidelines and Research and Evaluation (AGREE) instrument was developed and introduced. The objective of this study is to assess the methodological quality of CPGs on pancreatic cancer. Five databases (included MEDLINE and EMBASE) and guideline websites were searched till April, 2014. The methodological quality of the guidelines was assessed by 4 authors independently using the AGREE II instrument. From 2526 citations, 21 relevant guidelines were included. The overall agreement among reviewers was moderate (intraclass correlation coefficient = 0.86, 95% confidence interval 0.64-0.96). The mean scores were moderate for the domains "scope and purpose" and "clarity of presentation"; however, they were low for the domains "stakeholder involvement" (31.22), "rigor of development", "applicability", and "editorial independence". These domain scores were lower when compared with international levels. There are 5 (23.81%) guidelines that described the systematic methods for searching. Moreover, only 5 (23.81%) guidelines reported that methodological expertise were included in the guideline developing teams. The quality and transparency of the development process and the consistency in the reporting of pancreatic cancer guidelines need to be improved. Many other methodological disadvantages were identified. In the future, pancreatic cancer CPGs should base on the best available evidence rigorously developed and reported. Greater efforts are needed to provide high-quality guidelines that serve as a useful and reliable tool for clinical decision making in this field.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
He Z,Tian H,Song A,Jin L,Zhou X,Liu X,Guo W,Zhang Zdoi
10.1097/MD.0000000000000635subject
Has Abstractpub_date
2015-03-01 00:00:00pages
e635issue
12eissn
0025-7974issn
1536-5964pii
00005792-201503040-00005journal_volume
94pub_type
杂志文章相关文献
MEDICINE文献大全abstract:RATIONALE:Hypernatremia is a rare but fatal complication of hypertonic saline (HS) irrigation in hepatic hydatid disease. It needs careful monitoring and treatment. PATIENT CONCERNS:A 28-year-old woman with hepatic hydatid cysts who received operation treatment developed electrolyte disturbances. We also conducted a r...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007889
更新日期:2017-09-01 00:00:00
abstract::Chronic postsurgical pain (CPSP) is an important clinic problem. It is assessed that prevalence of chronic pain extends to 30% but it is contended that there are various risk factors. We aimed to evaluate the prevalence of chronic pain after hysterectomy, risk factors of chronicity, neuropathic features of pain, and s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004484
更新日期:2016-08-01 00:00:00
abstract::To evaluate the influence of various distributions of bone cement on the clinical efficacy of percutaneous kyphoplasty (PKP) in treating osteoporotic vertebrae compression fractures.A total of 201 OVCF patients (30 males and 171 females) who received PKP treatment in our hospital were enrolled in this study. According...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018217
更新日期:2019-12-01 00:00:00
abstract::Hospital readmission rates are used as a metric to measure quality patient care. While several tools predict readmissions based on patient-specific characteristics, this study assesses if physician characteristics correlate with hospital readmission rates.In a 5-year retrospective electronic record review at a single ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019363
更新日期:2020-03-01 00:00:00
abstract::This study aimed to assess the role of pre-designed route on computer tomography urography (CTU) in the ultrasound-guided percutaneous nephrolithotomy (PCNL) for renal calculus.From August 2013 to May 2016, a total of 100 patients diagnosed with complex renal calculus in our hospital were randomly divided into CTU gro...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000007215
更新日期:2017-06-01 00:00:00
abstract:RATIONALE:Spinal involvement in adult Langerhans cell histiocytosis (LCH) is rare, and epidural involvement is unusual. LCH is mostly indistinguishable from other spinal lesions such as infection, lymphoma, and metastasis. So, it could be easily misdiagnosed without suspicion. PATIENT CONCERNS:We report a case of a 33...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018794
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Aortic valve disease has become one of the important factors affecting human health. Aortic valve disease is a progressive disease, if not actively treated, the prognosis is poor. Aortic valve replacement (AVR) surgery is an important treatment for aortic valve disease. At present, the AVR surgery using biol...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023909
更新日期:2020-12-24 00:00:00
abstract:BACKGROUND:The role of real-time elastography (RTE)-targeted biopsy in the detection and diagnosis of prostate cancer (PCa) remains controversial. METHODS:We searched Medline, Embase, and Cochrane Library from inception to July 31, 2017 and used the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool to ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000010220
更新日期:2018-03-01 00:00:00
abstract::To assess prognostic factors for survival and describe Model for End-Stage liver disease (MELD) dynamics in human immunodeficiency virus+/hepatitis C virus+ (HIV+/HCV+) patients after an initial episode of hepatic decompensation.An HIV+/HCV+ cohort of patients experiencing an initial decompensation episode within the ...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000001239
更新日期:2015-07-01 00:00:00
abstract::Prior evidence suggested that inflammation and inflammatory cytokines polymorphisms might be essential in the development of coronary heart disease (CHD) and cognitive decline. The following study investigated the associations between interleukin-35 (IL-35) polymorphisms and cognitive decline in CHD patients over a 2-...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021390
更新日期:2020-07-31 00:00:00
abstract::Two clinical models have been described to predict the probability of pulmonary embolism: the Canadian (or Wells) model, and the Geneva model. A third model has been developed recently at our institution (the Pisa model). We compared the performance of the 3 models in 215 consecutive patients with suspected pulmonary ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/01.md.0000158793.32512.37
更新日期:2005-03-01 00:00:00
abstract::We present 2 rare cases of patients with uncontrolled hemorrhagic shock induced by traumatic ascending aortic pseudoaneurysm rupture into the esophagus. Two men were presented to the hospital after traffic accidents. Their chest radiograph showed no obvious signs of aortic damage or aortic pseudoaneurysms but only a s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000716
更新日期:2015-04-01 00:00:00
abstract::Several risk factors for pancreatic fistula had been widely reported, but there was no research focusing on the exocrine output of remnant gland.During the study period of January 2015 to September 2016, 82 patients accepted pancreaticoduodenectomy (PD, end-to-end dunking pancreaticojejunostomy with internal stent tub...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008451
更新日期:2017-11-01 00:00:00
abstract::Eighteen cases of mesothelioma, 7 benign and 11 malignant, were analyzed retrospectively. There were 5 females with benign tumors and 10 males with the malignant variety. The mean age was 59 years in the benign group and 55 years in those with malignant tumors. Exposure to asbestos was documented in one benign and fiv...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/00005792-197603000-00004
更新日期:1976-03-01 00:00:00
abstract:BACKGROUND:Pancreatic cancer (PC) is a lethal disease, however current screening methods unable to achieve early diagnosis. Blood-based microRNAs (miRNAs) are promising molecular biomarkers for detecting PC. This meta-analysis summaries studies identifying serum- or plasma-based miRNAs dysregulated in PC patients compa...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000012132
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:To explore the safety and efficacy of several special approaches of drainage for deep inaccessible intraabdominal and pelvic abscesses. METHODS:By searching of our institutional database, the clinical and radiologic information of all patients with special approaches of abscesses drainage was collected, con...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000012905
更新日期:2018-10-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002223.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/MD.0000000000007997
更新日期:2017-09-01 00:00:00
abstract:RATIONALE:Glossopharyngeal neuralgia (GPN) is a rare type of neuralgia. Depending on the cause, it is classified as idiopathic GPN and secondary GPN. Secondary GPN can also be caused by a mass effect or inflammation of the tonsils, the innervation area of glossopharyngeal nerve. PATIENT CONCERNS:The patient was diagno...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015234
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Melatonin is the "clock factor" generated from pineal gland dominating regular circadian rhythm in humans. Migraine is one of the most severe and debilitating primary headache disorders. Thus far, many diseases have been found to associate with melatonin, including the migraine. Therefore, melatonin's therap...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014099
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Shared decision making (SDM) is a process within the physician-patient relationship applicable to any clinical action, whether diagnostic, therapeutic, or preventive in nature. It has been defined as a process of mutual respect and participation between the doctor and the patient. The aim of this study is to...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000021389
更新日期:2020-08-07 00:00:00
abstract::Systemic lupus erythematosus (SLE) is associated with atherosclerosis, but the relationship between SLE and peripheral arterial occlusive disease (PAOD) remains unclear. We sought to investigate this relationship by comparing cardiovascular complications in patients with and without SLE.Data on patients from 2000 to 2...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002121
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Warm needle acupuncture (WNA) is a traditional Chinese medicine (TCM) therapy which combines technical advantages of acupuncture and moxibustion. Climacteric insomnia is a common symptom in climacteric women, which can seriously affect the physical and mental health of patients. Relevant studies have been re...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000015637
更新日期:2019-05-01 00:00:00
abstract::Early detection of metastatic infection in patients with Gram-positive bacteremia is important as morbidity and mortality are higher in the presence of these foci, probably due to incomplete eradication of clinically silent foci during initial treatment. We performed a prospective study in 115 patients with Staphyloco...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0b013e31824d7ed2
更新日期:2012-03-01 00:00:00
abstract:RATIONALE:Primary spinal glioblastoma multiforme (GBM) is a rare clinical entity with an aggressive course and an invariably dismal prognosis. Its clinical characteristics, radiologic and pathologic findings, and treatment protocols have been discussed in a few cases. PATIENT CONCERNS:A 15-year-old female was admitted...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006634
更新日期:2017-04-01 00:00:00
abstract::Disabled-2 (Dab2) is a clathrin and cargo-binding endocytic adaptor protein that plays a role in cellular trafficking of low-density lipoprotein receptor (LDLR). However, little is known about its involvement in coronary artery disease (CAD). Here, we aimed to investigate the association between Dab2 single-nucleotide...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020924
更新日期:2020-07-02 00:00:00
abstract::Most studies have focused on the prevalence of deep vein thrombosis (DVT) and pulmonary embolism in patients with chronic obstructive pulmonary disease (COPD) and acute exacerbation in Caucasian populations. DVT is supposedly less likely to occur among Asians than Caucasians, and the primary purpose of this study was ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001741
更新日期:2015-11-01 00:00:00
abstract:RATIONALE:Therapeutic or diagnostic thoracentesis is widely used in different clinical settings. Cardiac injury, a rare complication, could lead to fatal consequences. We describe a case of cardiac tamponade complicating thoracentesis that was recognized and rescued in a timely manner. PATIENT CONCERNS:A 42-year-old w...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019778
更新日期:2020-04-01 00:00:00
abstract::Assessment of sedentary behaviors in children and adolescents with type 1 diabetes (T1D), relative to the method of insulin therapy used, and in comparison to healthy controls.The study group consisted of 215 children with T1D, including 109 (50.7%) insulin pen and 106 (49.3%) insulqsain pump users. The control group ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015625
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:The efficacy and safety of oral tranexamic acid (TXA) remain controversial because of the small number of clinical studies. The aim of the present study was to compare the efficacy and safety of oral TXA with intravenous TXA in patients undergoing total hip arthroplasty and total knee arthroplasty in a syste...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000022999
更新日期:2020-10-30 00:00:00
abstract::This study aimed to evaluate the clinical usefulness of postoperative surveillance by ultrasound (PSU) in patients after breast cancer surgery.In this retrospective study, 324 patients with breast cancer after mastectomy were included between January 2006 and December 2008. The final-positive lesions (FPL) were diagno...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009244
更新日期:2017-12-01 00:00:00