Venous thromboembolism prophylaxis in patients hospitalized in medical wards: A real life experience.


:Venous thromboembolism (VTE) is a preventable cause of morbidity and mortality in acutely ill patients hospitalized in medical departments. Thromboprophylaxis with anticoagulants was shown to be safe and effective in medical patients with high risk to develop VTE. Despite guidelines recommendations, the rate of thromboprophylaxis in those patients is low. The objective of the study was to evaluate the rate of VTE risk assessment in routine medical department practice, the rate of eligible patients for thromboprophylaxis, the rate of patients who received thromboprophylaxis, and their outcome.Medical records of consecutive patients (3000 at 2013, 1000 at 2018) hospitalized in medical department were reviewed, retrospectively, for demographic, clinical characteristics, thromboprophylaxis treatment with enoxaparin and outcome (up to 90 days following discharge). Padua score was used for VTE risk assessment. VTE diagnosis was based on clinical suspicion.The mean patient's age (52.6% females) was 67.95 ± 21.56 years. 21% were eligible for thromboprophylaxis. Routine VTE risk assessment rate increased significantly following its incorporation into quality parameters, but the rate of treated patients was low (22% at 2013; 46% at 2018). The patients who received thromophylaxis were sicker compared to eligible patients without thromboprophylaxis. The rate of symptomatic VTE was low (0.24%; 0.12% and 0.55% for low and high VTE risk, respectively). Thromboprophylaxis did not have significant effect on the low number of VTE events. No major bleeding was observed.Major efforts are still needed to increase the rate of thromboprophylaxis in all eligible medical patients according to the guidelines recommendations.


Medicine (Baltimore)




Mahlab-Guri K,Otman MS,Replianski N,Rosenberg-Bezalel S,Rabinovich I,Sthoeger Z




Has Abstract


2020-02-01 00:00:00
















  • Effects of hepatic arterial infusion chemotherapy in the treatment of hepatocellular carcinoma: A meta-analysis.

    abstract:BACKGROUND:The potential benefits and safety of hepatic arterial infusion chemotherapy (HAIC) for the treatment of patients with hepatocellular carcinoma (HCC) remains inconsistent. Therefore, we conducted this meta-analysis of evaluate the efficacy and safety of HAIC in the treatment of HCC. METHODS:A comprehensive l...


    pub_type: 杂志文章,meta分析


    authors: Long GB,Xiao CW,Zhao XY,Zhang J,Li X

    更新日期:2020-06-26 00:00:00

  • A new intensive conditioning regimen for allogeneic hematopoietic stem cell transplantation in patients with refractory or relapsed acute myeloid leukemia.

    abstract::To explore the efficacy, and safety of the intensive conditioning regimen consisting of cladribine, cytarabine (Ara-C), and granulocyte colony-stimulating factor (G-CSF) plus modified busulfan (Bu) combined with cytoxan (Cy) (BuCy), prior to allogeneic hematopoietic stem cell transplantation (allo-HSCT) in patients wi...


    pub_type: 杂志文章


    authors: Wang J,Zhao J,Fei X,Yin Y,Cheng H,Zhang W,Gu J,Yang F,Yang Y,Xue S,Tian Z,He J,Zhang S,Wang X

    更新日期:2018-04-01 00:00:00

  • The aura of malignant tumor: Clinical analysis of malignant tumor-related pyogenic liver abscess.

    abstract::The global incidence of pyogenic liver abscess (PLA) is increasing, but related reports of malignant tumor-related PLA are infrequent. Potential malignant tumors of PLA have been reported, but there is no relevant predictive model for this subsection of patients.To explore the risk factors of malignant tumor-related P...


    pub_type: 杂志文章


    authors: Li W,Wu C,Qin M,Cai F,Huang J

    更新日期:2020-02-01 00:00:00

  • Salvage pancreaticoduodenectomy after complete response to chemoradiotherapy for a previously unresectable pancreatic adenosquamous carcinoma: a case report.

    abstract::Pancreatic cancer is known for its typically late presentation and poor survival rates, with overall 5-year survival of less than 5%. The role of chemotherapy alone or with radiotherapy in the management of locally advanced tumors continues to be an area of debate.We report a case of locally advanced, pancreatic adeno...


    pub_type: 杂志文章


    authors: Elias A,Chatzizacharias NA,Xanthis A,Corrie P,Davies S,Brais RJ,Jamieson NV,Praseedom RK,Huguet E,Harper SJF,Jah A

    更新日期:2015-02-01 00:00:00

  • Bioinformatics analysis to identify the critical genes, microRNAs and long noncoding RNAs in melanoma.

    abstract::Melanoma, which is usually induced by ultraviolet light exposure and the following DNA damage, is the most dangerous skin cancer. The purpose of the present study was to screen key molecules involved in melanoma.Microarray data of E-MTAB-1862 were downloaded from the ArrayExpress database, which included 21 primary me...


    pub_type: 杂志文章


    authors: Zhang Q,Wang Y,Liang J,Tian Y,Zhang Y,Tao K

    更新日期:2017-07-01 00:00:00

  • Straight sinus dural arteriovenous fistula presenting with reversible parkinsonism: A case report and literature review.

    abstract:RATIONALE:A dural arteriovenous fistula (DAVF) refers to an abnormal direct connection between an intracranial artery and a dural venous sinus. A DAVF presenting with parkinsonism is rare, and is therefore easily misdiagnosed. Therefore, early consideration of DAVF in the differential diagnosis of reversible parkinsoni...


    pub_type: 杂志文章


    authors: Pu J,Si X,Ye R,Zhang B

    更新日期:2017-12-01 00:00:00

  • Sedentary behaviors in children and adolescents with type 1 diabetes, depending on the insulin therapy used.

    abstract::Assessment of sedentary behaviors in children and adolescents with type 1 diabetes (T1D), relative to the method of insulin therapy used, and in comparison to healthy controls.The study group consisted of 215 children with T1D, including 109 (50.7%) insulin pen and 106 (49.3%) insulqsain pump users. The control group ...


    pub_type: 杂志文章


    authors: Czenczek-Lewandowska E,Leszczak J,Weres A,Baran J,Wyszyńska J,Grzegorczyk J,Lewandowski B,Mazur A

    更新日期:2019-05-01 00:00:00

  • Effectiveness of cognitive behavioral therapy on kinesiophobia and oral health-related quality of life in patients with temporomandibular disorders, study protocol for a randomized controlled trial.

    abstract:BACKGROUND:Temporomandibular disorders (TMD) is a common physical and psychological disease in dental department. Pain and mandibular limitation are the main reasons for patients to seek oral treatment. However, the presence of kinesiophobia, patients often catastrophize pain, so as to avoid mandibular movement, which ...


    pub_type: 杂志文章


    authors: Zhang Q,Zhang J,Ran W,Yu S,Jin Y

    更新日期:2020-11-20 00:00:00

  • Efficacy of dexmedetomidine for pain management in knee arthroscopy: A systematic review and meta-analysis.

    abstract:BACKGROUND:Dexmedetomidine showed some potential in pain control in patients undergoing knee arthroscopy. We conducted a systematic review and meta-analysis to explore the efficacy of dexmedetomidine in patients undergoing knee arthroscopy. METHODS:We searched the randomized controlled trials (RCTs) assessing the effe...


    pub_type: 杂志文章,meta分析,评审


    authors: Li C,Qu J

    更新日期:2017-10-01 00:00:00

  • An observational study on diagnosis index of metabolic disease with blood-stasis.

    abstract:INTRODUCTION:Treating blood stasis is effective in treating obesity and metabolic diseases in traditional Korean medicine. The aim of this prospective observational study is to determine the effectiveness of the diagnosis index for metabolic diseases with blood stasis by analyzing clinical data and blood samples. METH...


    pub_type: 临床试验,杂志文章


    authors: Ko MM,Jang S,Jung J

    更新日期:2020-07-02 00:00:00

  • Strategies to Make Ramadan Fasting Safer in Type 2 Diabetics: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials and Observational Studies.

    abstract::Ramadan is the holy month for Muslims whereby they fast from predawn to after sunset and is observed by all healthy Muslim adults as well as a large population of type 2 diabetic Muslims.To determine the comparative effectiveness of various strategies that have been used for type 2 diabetic Muslim who fast during Rama...


    pub_type: 杂志文章,meta分析,评审


    authors: Lee SWH,Lee JY,Tan CSS,Wong CP

    更新日期:2016-01-01 00:00:00

  • Comparison of the long-term efficacy of tenofovir and entecavir in nucleos(t)ide analogue-naïve HBeAg-positive patients with chronic hepatitis B: A large, multicentre, randomized controlled trials.

    abstract:OBJECTIVE:We conducted this study to compare the efficacy and safety of entecavir and tenofovir in the treatment of treatment-naïve HBV e antigen (HBeAg)-positive patients with chronic hepatitis B (CHB) for 144 weeks. METHODS:A total of 320 treatment-naïve HBeAg-positive CHB patients who received randomly a single reg...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Cai D,Pan C,Yu W,Dang S,Li J,Wu S,Jiang N,Wang M,Zhang Z,Lin F,Xin S,Yang Y,Shen B,Ren H

    更新日期:2019-01-01 00:00:00

  • Effect of social support and health education on depression scale scores of chronic stroke patients.

    abstract::Post-stroke depression (PSD) constitutes an important complication of stroke, leading to great disability. After stroke, the prevalence rate of depression is about 30%. Depression also affects rehabilitation motivation, delays function recovery, and increases family and social burden. The objective of this study was t...


    pub_type: 杂志文章,随机对照试验


    authors: Lin FH,Yih DN,Shih FM,Chu CM

    更新日期:2019-11-01 00:00:00

  • Assessment of regional right ventricular systolic function in patients with obstructive sleep apnea syndrome using velocity vector imaging.

    abstract::Obstructive sleep apnea syndrome (OSAS) is the most common type of sleep disorder which is associated with a series of cardiovascular disorders, including right ventricular (RV) dysfunction. However, it is difficult to assess the RV function systematically using a conventional echocardiography because RV has a complex...


    pub_type: 杂志文章


    authors: Li J,Wang Z,Li Y,Meng Y,Li R,Wang W,Fu X

    更新日期:2016-09-01 00:00:00

  • Increasing efficacy and reducing side effects in treatment of chronic anal fissures: A study of topical diazepam therapy.

    abstract::This is a single institution nonexperimental study intended to analyze the therapeutic efficacy of topical diazepam in treating symptoms of chronic anal fissures.Anal fissures are a common cause of anal pain. Conventional treatments include nonsteroidal anti-inflammatory drugs, topical creams, such as nitroglycerin an...


    pub_type: 杂志文章


    authors: Hang MTH,Smith BE,Keck C,Keshavarzian A,Sedghi S

    更新日期:2017-05-01 00:00:00

  • The prognostic value of left ventricular systolic function and cardiac biomarkers in pediatric severe sepsis.

    abstract::Echocardiography and cardiac biomarkers, such as cardiac troponin I (cTnI) and N-terminal pro-B-type natriuretic peptide (NT-pro BNP) are useful tools to evaluate cardiac dysfunction. Left ventricular systolic dysfunction (LVSD) is common in pediatric severe sepsis. The aim of this study is to evaluate the prognostic ...


    pub_type: 杂志文章


    authors: Li J,Ning B,Wang Y,Li B,Qian J,Ren H,Zhang J,Hu X

    更新日期:2019-03-01 00:00:00

  • Increasing Receipt of High-Tech/High-Cost Imaging and Its Determinants in the Last Month of Taiwanese Patients With Metastatic Cancer, 2001-2010: A Retrospective Cohort Study.

    abstract::One strategy for controlling the skyrocketing costs of cancer care may be to target high-tech/high-cost imaging at the end of life (EOL). This population-based study investigated receipt of high-tech/high-cost imaging and its determinants for Taiwanese patients with metastatic cancer in their last month of life.Indivi...


    pub_type: 杂志文章


    authors: Liu TW,Hung YN,Soong TC,Tang ST

    更新日期:2015-08-01 00:00:00

  • Kawasaki disease shock syndrome complicated with bilateral lung consolidation in a child: A case report.

    abstract:INTRODUCTION:Kawasaki disease (KD) is a systemic inflammatory disease. Standard imaging features of KD include interstitial and lobular inflammatory lesions in the lungs, while KD shock syndrome (KDSS), complicated with substantial consolidation and atelectasis in the lung, is rarely reported. PATIENTS CONCERNS:Herein...


    pub_type: 杂志文章


    authors: Song Y,Wei W,Liu L,Wang Y,Shi X,Li L

    更新日期:2020-07-17 00:00:00

  • Intralesional and subcutaneous application of Viscum album L. (European mistletoe) extract in cervical carcinoma in situ: A CARE compliant case report.

    abstract:RATIONALE:Carcinoma in situ (CIS) of the uterine cervix is a premalignant condition of squamous epithelium. The standard treatments are excision and ablation procedures; for women with positive margins, hysterectomy is recommended. PATIENT CONCERNS:A 47-year-old Peruvian woman with recurrent candidal vaginitis had bee...


    pub_type: 杂志文章


    authors: Reynel M,Villegas Y,Kiene H,Werthmann PG,Kienle GS

    更新日期:2018-11-01 00:00:00

  • Effect and safety of roflumilast for chronic obstructive pulmonary disease in Chinese patients.

    abstract:BACKGROUND:This trial aimed to evaluate the efficacy and safety of roflumilast for treating Chinese patients with chronic obstructive pulmonary disease (COPD). METHODS:A total of 120 patients with COPD were recruited and were randomly divided into 2 groups (an intervention group and a placebo group) at a 1:1 ratio. Pa...


    pub_type: 杂志文章,随机对照试验


    authors: Liu DY,Wang ZG,Gao Y,Zhang HM,Zhang YX,Wang XJ,Peng D

    更新日期:2018-02-01 00:00:00

  • A Causal Role of Genetically Elevated Circulating Interleukin-10 in the Development of Digestive Cancers: Evidence from Mendelian Randomization Analysis Based on 29,307 Subjects.

    abstract::Recent studies have observed a high level of circulating interleukin-10 (IL-10) in patients with digestive cancers, yet whether elevated IL-10 is causally associated with digestive cancers so far remained unresolved. We therefore meta-analyzed available observational studies with Mendelian randomization method to expl...


    pub_type: 杂志文章,meta分析,评审


    authors: Niu W,Pang Q,Lin T,Wang Z,Zhang J,Tai M,Zhang L,Zhang L,Gu M,Liu C,Qu K

    更新日期:2016-02-01 00:00:00

  • Leptin Is Associated With Persistence of Hyperglycemia in Acute Pancreatitis: A Prospective Clinical Study.

    abstract::Adipokines have many homeostatic roles, including modulation of glucose metabolism, but their role in the pathophysiology of hyperglycemia associated with acute and critical illnesses in general, and acute pancreatitis (AP) in particular, is largely unknown. This study aimed to investigate the relationship between a p...


    pub_type: 杂志文章


    authors: Kennedy JIC,Askelund KJ,Premkumar R,Phillips ARJ,Murphy R,Windsor JA,Petrov MS

    更新日期:2016-02-01 00:00:00

  • Metastatic infectious disease and clinical outcome in Staphylococcus aureus and Streptococcus species bacteremia.

    abstract::Early detection of metastatic infection in patients with Gram-positive bacteremia is important as morbidity and mortality are higher in the presence of these foci, probably due to incomplete eradication of clinically silent foci during initial treatment. We performed a prospective study in 115 patients with Staphyloco...


    pub_type: 杂志文章,随机对照试验


    authors: Vos FJ,Kullberg BJ,Sturm PD,Krabbe PFM,van Dijk APJ,Wanten GJA,Oyen WJG,Bleeker-Rovers CP

    更新日期:2012-03-01 00:00:00

  • Chronic chorioretinal detachment under normal intraocular pressure in eye with uveitic glaucoma after trabeculectomy: A case report.

    abstract:RATIONALE:Choroidal detachment is a major postoperative complication of trabeculectomy. Postoperative choroidal detachment occurs with low intraocular pressure (IOP), and is naturally resolved by elevation of IOP. We report a case of chronic chorioretinal detachment (CRD) in the eye with uveitic glaucoma after trabecul...


    pub_type: 杂志文章


    authors: Sakurai Y,Takayama K,Abe T,Takeuchi M

    更新日期:2020-01-01 00:00:00

  • External fixation combined with delayed internal fixation in treatment of tibial plateau fractures with dislocation.

    abstract::The aim of this study was to evaluate the clinical efficacy of external fixation, delayed open reduction, and internal fixation in treating tibial plateau fracture with dislocation.Clinical data of 34 patients diagnosed with tibial plateau fracture complicated with dislocation between January 2009 and May 2015 were re...


    pub_type: 杂志文章


    authors: Tao X,Chen N,Pan F,Cheng B

    更新日期:2017-10-01 00:00:00

  • Dorsal Penile Nerve Block With Ropivacaine-Reduced Postoperative Catheter-Related Bladder Discomfort in Male Patients After Emergence of General Anesthesia: A Prospective, Randomized, Controlled Study.

    abstract::Catheter-related bladder discomfort (CRBD) is a distressing symptom complex after surgery, especially in male patients who have had urinary catheterization under general anesthesia. In this prospective, randomized, controlled trial, we compared dorsal penile nerve block (DPNB) with 0.33% ropivacaine with intravenous t...


    pub_type: 杂志文章,随机对照试验


    authors: Li JY,Yi ML,Liao R

    更新日期:2016-04-01 00:00:00

  • Ten Years' Follow-Up on Combined Palmar and Dorsal Internal Fixation of Complex Distal Radius Fractures.

    abstract::Complex distal intra-articular radial fractures (AO Type C3) are rare, but are life-changing injuries. They are usually related to high-velocity trauma mechanisms in a working male population.We surveyed a cohort of these fractures treated in our institution to assess the functional long-term outcome.Twelve consecutiv...


    pub_type: 杂志文章


    authors: Iselin LD,Massy-Budmiger AS,Droeser RA,Mett TR,Babst R,Rikli DA

    更新日期:2016-05-01 00:00:00

  • Analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block.

    abstract:BACKGROUND:To evaluate the analgesic efficacy on defined areas of the abdomen and back after ultrasound-guided subcostal transversus abdominis plane (TAP) block using 0.25% levobupivacaine 0.5 mL/kg. METHODS:Twenty patients undergoing elective laparoscopic cholecystectomy, between 20 and 60 years of age with operative...


    pub_type: 临床试验,杂志文章


    authors: Ma J,Jiang Y,Tang S,Wang B,Lian Q,Xie Z,Li J

    更新日期:2017-03-01 00:00:00

  • Differences of DNA methylation patterns in the placenta of large for gestational age infant.

    abstract::To investigate the molecular mechanisms of later metabolic health changes in large for gestational age (LGA) newborns by analyzing deoxyribonucleic acid (DNA) methylation patterns in the placenta of LGA and appropriate for gestational age (AGA) newborns.A total of 6 placentas of LGA and 6 placentas of AGA newborns wer...


    pub_type: 杂志文章


    authors: Shen Z,Tang Y,Song Y,Shen W,Zou C

    更新日期:2020-09-25 00:00:00

  • Acute portal vein thrombosis after hepatectomy in a patient with hepatolithiasis: A case report and review of the literature.

    abstract:RATIONALE:Portal vein thrombosis is defined as any thrombosis that develops in the portal vein system. It is considered a very rare and extremely lethal complication of hepatopancreatobiliary surgery. PATIENT CONCERNS:Acute portal vein thrombosis after hepatectomy in patients with hepatolithiasisis very rare. Acute po...


    pub_type: 杂志文章


    authors: Zhang ZY,Dong KS,Zhang EL,Huang ZY,Chen XP,Dong HH

    更新日期:2018-06-01 00:00:00