Association study of gut flora in Wilson's disease through high-throughput sequencing.

abstract：:Kinesin family member 2A (KIF2A) is a member of Kinesin-13 family and involved in cell migration and cell signaling. Human epidermal growth factor receptor 2 (HER2-neu) is implicated in the development of many cancers. Both of these 2 proteins are upstream inducer of PI3K/AKT signaling pathway that plays an important ...

journal_title：Medicine

authors： Wang D,Zhu H,Ye Q,Wang C,Xu Y

更新日期：2016-02-01 00:00:00

abstract：RATIONALE:Congenital myasthenic syndrome (CMSs) are a group of rare genetic disorders of the neurological junction, which can result in structural or functional weakness. Here, we characterized a case of CMS in order to clarify the diagnosis and expand the understanding of it. The molecular diagnosis had implications f...

journal_title：Medicine

authors： Yang K,Cheng H,Yuan F,Meng L,Yin R,Zhang Y,Wang S,Wang C,Lu Y,Xi J,Lu Q,Chen Y

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Health education during pregnancy is important to improve maternal and children outcomes. However, the strategies must be specifically designed for each context and demographic characteristics. Our objective was identify health education strategies targeting pregnant women with the intention of improving res...

journal_title：Medicine

authors： Herval ÁM,Oliveira DPD,Gomes VE,Vargas AMD

更新日期：2019-06-01 00:00:00

abstract：:Lymphoid follicles/aggregates in gastric biopsies have been traditionally linked to Helicobacter pylori gastritis, and less commonly to other inflammatory and neoplastic conditions. The frequency of such aggregates in normal stomachs has yet to be adequately evaluated. This is especially relevant when it comes to diag...

journal_title：Medicine

authors： Chakhachiro Z,Saroufim M,Safadi B,Attieh M,Assaf N,Shamseddine G,Tamim H,Boulos F

更新日期：2020-02-01 00:00:00

abstract：:Prosthetic Valve Thrombosis (PVT), in spite of the advances in the valve design and the material used, remains a serious complication of mechanical cardiac valve replacement. The factors influencing the development of PVT are: thrombogenicity of the valve, hemodynamics of the transprosthetic blood flow and ineffective...

journal_title：Medicine

authors： Sr K,G B,Jain S,Moorthy N,Manjunath SC,Christopher R

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Pneumonia is one of the most important characteristics of coronavirus disease 2019 (COVID-19) and imaging findings of COVID-19 pneumonia are diverse and change over disease course. However, the detailed clinical course of organizing pneumonia (OP) caused by COVID-19 has not been clarified. PATIENT CONCERN...

journal_title：Medicine

authors： Okamori S,Lee H,Kondo Y,Akiyama Y,Kabata H,Kaneko Y,Ishii M,Hasegawa N,Fukunaga K

更新日期：2020-08-28 00:00:00

abstract：RATIONALE:Congenital diaphragmatic hernia (CDH) associated congenital anomalies are present in about 25%. Congenital short esophagus (CSE) is a relatively rare condition. Both CDH and congenital intrathoracic stomach caused by CSE can be diagnosed in utero. However, CSE can be easily misdiagnosed in utero. PATIENT CON...

journal_title：Medicine

authors： Xia B,Hong C,Tang J,Liu C,Yu G

更新日期：2017-12-01 00:00:00

abstract：:Quality of life (QoL) is a matter of concern in both healthy and diseased individuals. Lifestyle factors such as physical activity and sleep have a direct impact on QoL. In this context, interactions between activity time expenditure and QoL might be different in comorbid and non comorbid patients. Besides, the quanti...

journal_title：Medicine

authors： Suarez-Villar R,Martinez-Urbistondo D,Fernandez MA,Lopez-Cano M,Fernandez E,Dominguez A,Prosper L,Rodriguez-Cobo A,Tinoco MEC,Nadal P,Risco CR,Fernández PV,Martínez JA

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND:To comprehensively evaluate the treatment efficacy and safety of silymarin for patients with glucose/lipid metabolic dysfunction using a meta-analysis. METHODS:A systematic literature search in PubMed, EMBASE and Cochrane Library databases was performed up to October 1, 2019. STATA 13.0 software was used to...

journal_title：Medicine

authors： Xiao F,Gao F,Zhou S,Wang L

更新日期：2020-10-02 00:00:00

abstract：:Enterprise stent has been widespread used in wide-necked intracranial aneurysms and good efficacy has been achieved, but there are few reports on its applications in very small ruptured intracranial aneurysms in literatures. This study aimed to evaluate the safety and efficacy of Enterprise stent-assisted coiling embo...

journal_title：Medicine

authors： Qin F,Li Z,Fang X,Zhao X,Liu J,Wu D,Lai N

更新日期：2017-08-01 00:00:00

abstract：RATIONALE:Intramuscular hemangiomas are rare benign vascular neoplasms, merely accounting for 0.8% of all hemangiomas. Moreover, there are few case reports of intramuscular hemangiomas in the upper extremities. PATIENT CONCERNS:A 24-year-old male patient presented with a 5-year history of intermittent pain of the righ...

journal_title：Medicine

authors： Liu Y,Li R,Liu Z,Wang S,Lu L

更新日期：2019-02-01 00:00:00

abstract：:The aim of our study was to compare the clinical and surgical characteristics of pregnant and nonpregnant women with surgically verified ovarian torsion, as well as the differences among 3 trimesters during pregnancy.We conducted a retrospective study of patients diagnosed with surgically proven ovarian torsion in our...

journal_title：Medicine

authors： Wu WF,Wang ZH,Xiu YL,Xie X,Pan M

更新日期：2020-06-12 00:00:00

abstract：PURPOSE:Neovascular glaucoma (NVG) is a severe secondary glaucoma with uncontrolled intraocular pressure that leads to serious eye pain and vision loss. Presently, the therapeutic strategies for NVG are diverse, but the therapeutic effects are still not ideal. We performed a network analysis to assess the effect of mul...

journal_title：Medicine

authors： Dong Z,Gong J,Liao R,Xu S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Unstable angina (UA) is a clinically common coronary heart disease. Zhishi xiebai guizhi decoction (ZXGD) has been widely used in the management of UA, although its effective evidence is not clear and there is no systematic review regarding its efficacy and safety. Therefore, we conduct this systematic revie...

journal_title：Medicine

authors： Tang Y,Cai H,Zhan Z,Luo Y,Huang Y,Chen D,Chen B

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Ischemic stroke often leads to lifelong disability or death in stroke patients. It is one of the most common causes of death and disability worldwide, so it is a global health problem. The objective of this protocol is to provide the methods for using overview and network meta-analysis to identify the more e...

journal_title：Medicine

authors： Zhang Y,Yu HJ,Shi SZ,Wang JC

更新日期：2019-04-01 00:00:00

abstract：:Methemoglobin is a form of hemoglobin that does not bind oxygen. When its concentration is elevated in red blood cells, functional anemia and tissue hypoxia may occur. We performed a retrospective case series to describe the cases of acquired methemoglobinemia (methemoglobin level >2%) detected and the clinical circum...

journal_title：Medicine

authors： Ash-Bernal R,Wise R,Wright SM

更新日期：2004-09-01 00:00:00

abstract：RATIONALE:Pilot studies have reported that patients with systemic lupus erythematosus (SLE) appear more likely to develop into neoplasia, especially lymphatic hyperplasia diseases. To our knowledge, this is the first case report of the concomitant onset of SLE and primary breast diffuse large B-cell lymphoma (PB-DLBCL)...

journal_title：Medicine

authors： Shen F,Li G,Jiang H,Zhao S,Qi F

更新日期：2020-08-14 00:00:00

abstract：:Bisphosphonates have been commonly used for the treatment of osteoporosis. However, there have been recent case reports of atypical fractures citing their long-term use, which inhibits the turnover of bone components. A 64-year-old woman visited the outpatient clinic with pain in her right thigh and ambulation difficu...

journal_title：Medicine

authors： Kim HS,Jung HY,Kim MO,Joa KL,Kim YJ,Kwon SY,Kim CH

更新日期：2015-02-01 00:00:00

abstract：BACKGROUNDS:A large number of studies have reported the relationships between serum lactate dehydrogenase (LDH) and prognosis of osteosarcoma. However, the result is still controversial and no consensus has been reached. Therefore, we performed a meta-analysis to evaluate the prognostic role of serum LDH in osteosarcom...

journal_title：Medicine

authors： Fu Y,Lan T,Cai H,Lu A,Yu W

更新日期：2018-05-01 00:00:00

abstract：:1. Studies on eight patients were performed to clarify the mechanism(s) of altered sodium metabolism and volume regulation in SIADH. The mechanism controlling water excretion was also studied to determine whether there is evidence that altered osmoregulation may be the basis for inappropriate ADH secretion in some pat...

journal_title：Medicine

authors： Cooke CR,Turin MD,Walker WG

更新日期：1979-05-01 00:00:00

abstract：INTRODUCTION:In blunt traumatic superficial femoral arterial (SFA) injuries, hemorrhage from the branches without injury to the main artery is rare, but can lead to serious complications, such as compartment syndrome affecting the clinical outcomes. Although open surgical repair has been the standard approach to periph...

journal_title：Medicine

authors： Oh CH,Kim Y,Lee JH,Kim HR,Go SJ

更新日期：2020-07-02 00:00:00

abstract：RATIONALE:Intraductal papillary and mucinous neoplasms of the pancreas (IPMN) are preneoplastic lesions diagnosed with an increasing incidence. Recently, several groups have described, in up to 70% of IPMN, activating mutations of the G-protein alpha stimulatory sub-unit (Gsα subunit) gene (GNAS). GNAS-activating somat...

journal_title：Medicine

authors： Gaujoux S,Pasmant E,Silve C,Mehsen-Cetre N,Coriat R,Rouquette A,Douset B,Prat F,Leroy K

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Positional change affects the cuff pressure of an endotracheal tube (ETT) in treacheally intubated patients. We compared the cuff pressure of a TaperGuard ETT and a cylindrical ETT after lateral rotation of head during middle ear surgery. METHODS:Fifty-two patients aged 18-70 years underwent a tympanomastoi...

journal_title：Medicine

authors： Choi E,Park Y,Jeon Y

更新日期：2017-03-01 00:00:00

abstract：:Serum adiponectin levels have been suggested to be predictors of type 2 diabetes mellitus in diverse populations. However, the relationship between circulating adiponectin levels and the risk of development of type 2 diabetes in postmenopausal women has not been investigated.A total of 382 healthy postmenopausal women...

journal_title：Medicine

authors： Darabi H,Raeisi A,Kalantarhormozi MR,Ostovar A,Assadi M,Asadipooya K,Vahdat K,Dobaradaran S,Nabipour I

更新日期：2015-08-01 00:00:00

abstract：:Determination of Fuhrman grade (FG) on biopsies of renal masses is relatively inaccurate, being prone to underestimating the true grade as ascertained from surgical specimens. This study evaluated whether anatomical features of tumors could predict tumor upgrading between core biopsies and surgical specimens. We prosp...

journal_title：Medicine

authors： Zhang GM,Zhu Y,Gan HL,Wang HK,Shi GH,Zhang HL,Dai B,Wang CF,Ye DW

更新日期：2015-02-01 00:00:00

abstract：:The aim of this study was to provide an innovative nomogram to predict the risk of >2 positive nodes in patients fulfilling the Z0011 criteria with 1-2 sentinel lymph nodes (SLNs) only retrieved.From 2007 to 2017, at the Breast Unit of ICS Maugeri Hospital 271 patients with 1-2 macrometastatic SLNs, fulfilling the Z00...

journal_title：Medicine

authors： Corsi F,Sorrentino L,Albasini S,Bossi D,Morasso C,Villani L,Truffi M

更新日期：2020-08-28 00:00:00

abstract：RATIONALE:Acquired vertical diplopia is commonly observed in trochlear nerve palsy, often resulting from blunt head trauma or vascular problems. It is rarely caused by tumorous conditions or space occupying lesion. We report the first case of Onodi cell mucocele causing isolated trochlear nerve palsy. PATIENT CONCERNS...

journal_title：Medicine

authors： Kwon KW,Oh JS,Kim JW,Yoo RE,Kang JG

更新日期：2019-05-01 00:00:00

abstract：:Early detection of metastatic infection in patients with Gram-positive bacteremia is important as morbidity and mortality are higher in the presence of these foci, probably due to incomplete eradication of clinically silent foci during initial treatment. We performed a prospective study in 115 patients with Staphyloco...

journal_title：Medicine

authors： Vos FJ,Kullberg BJ,Sturm PD,Krabbe PFM,van Dijk APJ,Wanten GJA,Oyen WJG,Bleeker-Rovers CP

更新日期：2012-03-01 00:00:00

abstract：:The Tonnis radiographic classification of developmental dysplasia of the hip (DDH) has been widely used. The International Hip Dysplasia Institute (IHDI) classification, a new classification system recently developed by the IHDI, is beginning to be applied to evaluate DDH with the absence of an ossification center. Th...

journal_title：Medicine

authors： Miao M,Cai H,Hu L,Wang Z

更新日期：2017-01-01 00:00:00

abstract：ABSTRACT:This study aimed to examine whether marginal sinus placenta previa, defined as when the marginal sinus just reaches the internal cervical os and placental parenchyma might be >2 cm from the internal cervical os, can be diagnosed using ultrasonography (US). We identified the placenta previa cases that underwent...

journal_title：Medicine

authors： Ishibashi H,Miyamoto M,Shinmoto H,Soga S,Iwahashi H,Kakimoto S,Matsuura H,Sakamoto T,Hada T,Suzuki R,Takano M

更新日期：2021-01-08 00:00:00