Abstract:
:Determination of Fuhrman grade (FG) on biopsies of renal masses is relatively inaccurate, being prone to underestimating the true grade as ascertained from surgical specimens. This study evaluated whether anatomical features of tumors could predict tumor upgrading between core biopsies and surgical specimens. We prospectively enrolled 249 patients undergoing surgical resection of solid renal masses at our institution from 2012 to 2013. Tumor anatomical features were defined using RENAL nephrometry scores. Two peripheral and 1 central ex vivo core biopsies were taken from surgical specimens with an F18-gauge needle. Logistic regression was used to assess associations between covariates and FG upgrading. A comprehensive nomogram was constructed to quantitate the probability of tumor upgrading. The median tumor size was 4.75 cm and FG upgrading occurred in 43.6% of cases. In tumors of low, intermediate, and high complexity, the risk of FG upgrading was 22.0%, 47.6%, and 50.6%, respectively. According to multivariate analyses, anatomical features R (radius) and L (location) scores correlated significantly with FG upgrading. A combination of anatomical features and core biopsy findings predicted tumor upgrading with an accuracy of 0.884. With a threshold of 30%, our nomogram identified 92.4% of cases with upgrading; however, it overrated 26.8% of patients without upgrading. This ex vivo prospective study demonstrated that RENAL nephrometry score can aid prediction of FG upgrading between core biopsies and surgical specimens. Our nomogram uses anatomical features to predict true FG from renal biopsies.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Zhang GM,Zhu Y,Gan HL,Wang HK,Shi GH,Zhang HL,Dai B,Wang CF,Ye DWdoi
10.1097/MD.0000000000000581subject
Has Abstractpub_date
2015-02-01 00:00:00pages
e581issue
8eissn
0025-7974issn
1536-5964pii
00005792-201502040-00012journal_volume
94pub_type
临床试验,杂志文章相关文献
MEDICINE文献大全abstract::The global incidence of pyogenic liver abscess (PLA) is increasing, but related reports of malignant tumor-related PLA are infrequent. Potential malignant tumors of PLA have been reported, but there is no relevant predictive model for this subsection of patients.To explore the risk factors of malignant tumor-related P...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019282
更新日期:2020-02-01 00:00:00
abstract::This study aimed to detail the clinical outcomes of patients suffering from celiac arterial aneurysm (CAA) that underwent treatment via stent occlusion.This is a single-center, retrospective study. A total of 8 consecutive CAA patients were treated via stent occlusion from March 2014 to September 2018 at our hospital....
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023448
更新日期:2020-11-25 00:00:00
abstract:BACKGROUND:Treatment for osteoporosis in the community in patients who were operated for hip fracture appears to be suboptimal at best. Evidence regarding treatment beyond the 1st year after surgery is scarce. We examined the association between discharge recommendations for treatment of osteoporosis in patients suffer...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004141
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Prostaglandin E1 (P) or methylcobalamin (M) treatment has been suggested as a therapeutic approach for diabetic peripheral neuropathy (DPN) in many clinical trial reports. However, the combined effects of 2 drugs still remain dubious. OBJECTIVE:The aim of this report was to evaluate the efficacy of M plus P...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000013020
更新日期:2018-11-01 00:00:00
abstract::High occupational stress and burnout among physicians can lead to sleep problems, anxiety, depression, and even suicide. Even so, the actual risk for these behavioral health problems in health care-seeking physicians has been seldom explored. The aim of this study was to determine whether physicians have higher odds o...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001323
更新日期:2015-09-01 00:00:00
abstract:RATIONALE:Congenital myasthenic syndrome (CMSs) are a group of rare genetic disorders of the neurological junction, which can result in structural or functional weakness. Here, we characterized a case of CMS in order to clarify the diagnosis and expand the understanding of it. The molecular diagnosis had implications f...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010347
更新日期:2018-04-01 00:00:00
abstract:RATIONALE:Adrenal hepatoid adenocarcinoma typically secretes alpha-fetoprotein (AFP). Here, we report a case of non-AFP-producing adrenal hepatoid adenocarcinoma. Next-generation sequencing (NGS) was conducted to identify gene mutations. PATIENT CONCERNS:A 64-year-old man presented with mild back pain and unexplained ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000012336
更新日期:2018-09-01 00:00:00
abstract::The radial artery has been increasingly used for its favorable safety profile. However, no conclusive data are available on the optimal sheath size. In particular, it is seemingly difficult to weight both advantages and disadvantages of narrower versus larger sheaths size. Despite several studies were performed to com...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000002170
更新日期:2015-12-01 00:00:00
abstract::This study investigated the impacts of renin-angiotensin system inhibitors (RASIs) on 2-year clinical outcomes in diabetes and dyslipidemic acute myocardial infarction (AMI) patients after a successful percutaneous coronary intervention (PCI) using newer-generation drug-eluting stents (DESs).A total of 16,997 AMI pati...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021289
更新日期:2020-07-24 00:00:00
abstract:BACKGROUND:Preterm infants are at an increased risk of sucking problems, swallowing difficulty, and poor nourishment. During the neonatal period, the neurobehavioral organization of a preterm baby is poor compared with that of appropriate gestational age infants. Kinesio Taping has been widely used for edema control, j...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000004458
更新日期:2016-08-01 00:00:00
abstract::To investigate the risk factors of nosocomial pneumonia (NP) in elderly patients with acute cerebral infarction (ACI).In this study, 324 aged 70 years and over patients with ACI who were admitted to the inpatient department of TianJin First Hospital (China) from January 2012 to February 2018 were retrospectively analy...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015045
更新日期:2019-03-01 00:00:00
abstract:RATIONALE:Primary pulmonary meningiomas are extremely rare, and only a few cases have been reported in the medical literature. Imaging findings of primary pulmonary meningiomas have been reported even more rarely. PATIENT CONCERNS:We present the case of a 54-year-old male patient with cough and sputum lasting for 20 y...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009651
更新日期:2018-01-01 00:00:00
abstract::Presently noninvasive methods were employed to the diagnosis of nonalcoholic fatty liver disease (NAFLD), including fatty liver index (FLI), hepatic steatosis index (HSI), product of fasting triglyceride and glucose levels (TyG), and single nucleotide polymorphism (SNP), whereas the accuracy of those indexes need to b...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010272
更新日期:2018-03-01 00:00:00
abstract::Melanoma, which is usually induced by ultraviolet light exposure and the following DNA damage, is the most dangerous skin cancer. The purpose of the present study was to screen key molecules involved in melanoma.Microarray data of E-MTAB-1862 were downloaded from the ArrayExpress database, which included 21 primary me...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007497
更新日期:2017-07-01 00:00:00
abstract::This study is to establish the nomogram model and provide clinical therapy decision-making for extensive-stage small-cell lung cancer (ES-SCLC) patients with different metastatic sites using the Surveillance, Epidemiology, and End Results (SEER) Program.A total of 10,025 patients of ES-SCLC with metastasis from Januar...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021798
更新日期:2020-08-14 00:00:00
abstract::VASA, also known as DDX4, is reported to be specifically expressed in cells belonging to the germ cell lineage, both in males and females. Therefore, it could be an informative protein biomarker to be applied on semen to differentiate between obstructive and nonobstructive azoospermia (OA and NOA, respectively). In ad...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007489
更新日期:2017-07-01 00:00:00
abstract::There is an increased enthusiasm in treating osteolytic metastatic acetabulum via injecting polymethyl-methacrylate (PMMA) as a bone filler to provide pain relief and potential structural support. The aim of this respective study is to determine the function and quality of life improvement after cement acetabuloplasty...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017029
更新日期:2019-09-01 00:00:00
abstract::The incidence of type II diabetes mellitus (T2DM) is increasing worldwide and affecting the quality of people's life. This study was designed to evaluate the effect of care intervention on body weight and glycemic parameters in obese T2DM patients.One hundred twenty-six obese T2DM cases were randomly divided into 2 gr...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000007524
更新日期:2017-10-01 00:00:00
abstract::The purpose of this study was to develop and validate a finite element (FE) model to predict vertebral bone strength in vitro using multidetector computed tomography (MDCT) images in multiple myeloma (MM) patients, to serve as a complementing tool to assess fracture risk. In addition, it also aims to differentiate MM ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005825
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The corona virus disease 2019 (COVID-19) has caused a global pandemic, there are no specific drugs and vaccines for epidemic control at present. More and more clinical practice shows that traditional Chinese medicine has played an important role in the outbreak. Among them, Qingfei Paidu decoction (QPD) comb...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020489
更新日期:2020-05-29 00:00:00
abstract:BACKGROUND:the difference in the risk of thyroid malignancy for patients with multinodular goiter (MNG) and solitary nodular goiter (SNG) remains controversial. Although total thyroidectomy (TT) is the current preferred surgical option for MNG, permanent hypothyroidism in these patients may be a concern. Therefore, we ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004194
更新日期:2016-07-01 00:00:00
abstract::Viral encephalitis is a serious complication of hand, foot, and mouth disease (HFMD), but characteristics of cytokines response in enterovirus 71 (EV-71) and/or coxsackievirus A16 (CV-A16) associated HFMD with or without viral encephalitis remained unclear.We performed a multigroup retrospective study and compared the...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001137
更新日期:2015-07-01 00:00:00
abstract::High prevalence of obstructive sleep apnea (OSA) has increased the demands for more convenient and accessible diagnostic devices other than standard in-lab polysomnography (PSG). Despite the increasing utility of photoplethysmograph (PPG), it remains understudied in underserved populations. This study aimed to evaluat...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006755
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:The study determined the effect of cognitive-behavioral therapy (CBT) with music in reducing physics test anxiety among secondary school students as measured by generalized test anxiety scale. METHODS:Pre-test post-test randomized control trial experimental design was adopted in this study. A total of 83 se...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000016406
更新日期:2020-04-01 00:00:00
abstract::To study the changes in 3 mutations related with hepatitis B e antigen (HBeAg) in patients with HBeAg-positive chronic hepatitis B (CHB) during interferon therapy.HBeAg seroconversion is a major therapeutic milestone for patients with HBeAg-positive CHB. The precore mutation G1896A and the basal core promoter mutation...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002657
更新日期:2016-02-01 00:00:00
abstract:RATIONALE:F-fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has an important role in the diagnosis of various malignancies. However, F-18 FDG can also exhibit intense accumulation in tissues in inflammatory conditions such as active tuberculosis (TB) and sarcoidosis. PATIENT CONCE...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007248
更新日期:2017-07-01 00:00:00
abstract:RATIONALE:Diabetic foot ulcer is a severe complication of diabetes, and most patients with diabetic foot ulcer require amputation. The incidence of Budd-Chiari syndrome is low; it is relatively rare. Diabetic foot ulcer combined with Budd-Chiari syndrome has not been reported so far. PATIENT CONCERNS:A 52-year-old man...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014224
更新日期:2019-01-01 00:00:00
abstract::To explore interleukin-17 (IL-17) and its epigenetic regulation during the progression of chronic hepatitis B virus (HBV) infection.A total of 162 patients with chronic HBV infection, including 75 with chronic hepatitis B (CHB), 54 with hepatitis B-associated liver cirrhosis and 33 with hepatitis B-associated hepatoce...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015924
更新日期:2019-06-01 00:00:00
abstract::This study aimed to compare the differences in radiological outcomes and complications between single- and multilevel anterior cervical discectomy and fusion (ACDF) by using a polyetheretherketone (PEEK) cage-plate fusion system.Fifty-seven patients who underwent ACDF via the PEEK cage-plate fusion system were enrolle...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014277
更新日期:2019-02-01 00:00:00
abstract::This meta-analysis mainly summarized the studies reporting an association between statin use and cancer-specific mortality and recurrence or progression of cancer patients.We systematically searched for studies about the statin used in cancer patients in electronic databases, including PubMed, Web of Science, Cochrane...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000019596
更新日期:2020-04-01 00:00:00