A new sensitive and accurate model to predict moderate to severe obstructive sleep apnea in patients with obesity.

Abstract:

:Obstructive sleep apnea (OSA) has a high prevalence in patients with obesity. Only patients with clinical symptoms of OSA are admitted to polysomnography; however, many patients with OSA are asymptomatic. We aimed to create and validate a population-based risk score that predicts the severity of OSA in patients with obesity.We here report the cross-sectional analysis at baseline of an ongoing study investigating the long-term effect of bariatric surgery on OSA. One-hundred sixty-one patients of the Obesity Center of the Catholic University Hospital in Rome, Italy were included in the study. The patients underwent overnight cardiorespiratory monitoring, blood chemistry analyses, hepatic ultrasound, and anthropometric measurements. The patients were divided into 2 groups according OSA severity assessed by the apnea-hypopnea index (AHI): AHI < 15 = no or mild and AHI ≥ 15 moderate to severe OSA. A statistical prediction model was created and validated. C statistics was used to evaluate the discrimination performance of the model.The prevalence of OSA was 96.3% with 74.5% of the subjects having moderate/severe OSA. Sex, body mass index, diabetes, and age were included in the final prediction model that had excellent discrimination ability (C statistics equals to 83%). An OSA risk chart score for clinical use was created.Patients with severe obesity are at a very high risk for moderate or severe OSA in particular if they are men, older, more obese, and/or with type 2 diabetes. The OSA risk chart can be useful for general practitioners and patients as well as for bariatric surgeons to select patients with high risk of moderate to severe OSA for further polysomnography.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Ahlin S,Manco M,Panunzi S,Verrastro O,Giannetti G,Prete A,Guidone C,Berardino ADM,Viglietta L,Ferravante A,Mingrone G,Mormile F,Capristo E

doi

10.1097/MD.0000000000016687

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

e16687

issue

32

eissn

0025-7974

issn

1536-5964

pii

00005792-201908090-00030

journal_volume

98

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Nivolumab therapy for metastatic collecting duct carcinoma after nephrectomy: A case report.

    abstract:RATIONALE:Collecting duct carcinoma (CDC) is a rare type of nonclear renal cell carcinoma, often presenting at an advanced stage of the disease, and standard treatment guidelines have not been established. PATIENT CONCERNS:A 73-year-old man was admitted to our hospital with complaints of fever and lower right back pai...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013173

    authors: Yasuoka S,Hamasaki T,Kuribayashi E,Nagasawa M,Kawaguchi T,Nagashima Y,Kondo Y

    更新日期:2018-11-01 00:00:00

  • Antifungal Treatment is Not Required for Immunocompetent Individuals With Asymptomatic Esophageal Candidiasis.

    abstract::Although esophageal candidiasis (EC) is an opportunistic infection, asymptomatic EC (AEC) is occasionally encountered in otherwise healthy individuals. This study evaluates the impact of antifungal treatment in immunocompetent individuals with AEC and investigates risk factors for persistent or recurrent EC. The autho...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001969

    authors: Min YW,Kim E,Son HJ,Kim JJ,Rhee PL

    更新日期:2015-11-01 00:00:00

  • Successful treatment of metastatic adrenocortical carcinoma in the spine: A case report and literature review.

    abstract:RATIONALE:Adrenocortical carcinoma is a rare aggressive type of cancer whose prognosis is poor, particularly for metastatic entities. Metastatic adrenocortical carcinoma in the spine is a rare disease with no standard curative managements yet. The objective of this study is to report a very rare case of spinal metastas...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000018259

    authors: Liu S,Zhou X,Song A,Huo Z,Wang Y,Liu Y

    更新日期:2019-12-01 00:00:00

  • Association between the A46G polymorphism (rs1042713) in the β2-adrenergic receptor gene and essential hypertension susceptibility in the Chinese population: A PRISMA-compliant meta-analysis.

    abstract:BACKGROUND:Recently, many studies have been conducted to investigate the relationship between the A46G polymorphism in the β2-adrenergic receptor (ADRB2) gene and essential hypertension risk in the Chinese population. However, the results of previous studies were conflicting. OBJECTIVES:The present study aimed to inve...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000023164

    authors: Yan L,Wang H,Liu P,Wang M,Chen J,Zhao X

    更新日期:2020-11-13 00:00:00

  • Association between KRAS G13D mutations and anastomotic recurrence in colorectal cancer: Two case reports.

    abstract:RATIONALE:The prevalence of anastomotic recurrence (AR) in colorectal cancer (CRC) after resection of the primary tumor (PT) is 5% to 14%. However, no association has been observed between specific somatic genetic alterations and AR. Such associations may shed light on the mechanism of AR. PATIENT CONCERNS:We experien...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014781

    authors: Okada S,Hata K,Kawai K,Yamamoto Y,Tanaka T,Nishikawa T,Sasaki K,Kaneko M,Emoto S,Murono K,Nozawa H

    更新日期:2019-03-01 00:00:00

  • Effectiveness of physiotherapy on quality of life in children with asthma: Study protocol for a systematic review and meta-analysis.

    abstract:BACKGROUND:Asthma is the most common chronic lung disease in childhood, leading to a great burden to the healthcare system worldwide. Despite the medication treatment, physiotherapy is now applied for asthmatic children aiming to improve their lung function and life quality. However, the effectiveness of physiotherapy ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016195

    authors: Zhang W,Liu L,Yang W,Liu H

    更新日期:2019-06-01 00:00:00

  • Rapid detection of urinary soluble intercellular adhesion molecule-1 for determination of lupus nephritis activity.

    abstract::The current methods of monitoring the activity of lupus nephritis (LN) may cause unnecessary hospital visits or delayed immunosuppressive therapy. We aimed to find a urinary biomarker that could be developed as a home-based test for monitoring the activity of LN.Urine samples were collected immediately before a renal ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011287

    authors: Wang Y,Tao Y,Liu Y,Zhao Y,Song C,Zhou B,Wang T,Gao L,Zhang L,Hu H

    更新日期:2018-06-01 00:00:00

  • Acute Primary Pneumococcal Purulent Pericarditis With Cardiac Tamponade: A Case Report and Literature Review.

    abstract::Bacterial pericarditis is a rapidly progressive and highly fatal infection, and is often diagnosed postmortem in half of the cases. Even with drainage and antibiotics, the mortality rate is high. Gram-positive cocci, specifically Streptococcus penumoniae, have been the most common cause of bacterial pericarditis with ...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000001709

    authors: Patel H,Patel C,Soni M,Patel A,Banda V

    更新日期:2015-10-01 00:00:00

  • Extracorporeal membrane oxygenation support in post-traumatic cardiopulmonary failure: A 10-year single institutional experience.

    abstract::Patients with multiple traumas associated with cardiopulmonary failure have a high mortality rate; however, such patients can be temporarily stabilized using extracorporeal membrane oxygenation (ECMO), providing a bridge to rescue therapy. Using a retrospective study design, we aimed to clarify the prognostic factors ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006067

    authors: Lin CY,Tsai FC,Lee HA,Tseng YH

    更新日期:2017-02-01 00:00:00

  • The effects of psychotherapy for depressed or posttraumatic stress disorder women with childhood sexual abuse history: Meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Depression and posttraumatic stress disorder (PTSD) are the most common mental disorders of women suffered from childhood sexual abuse histories. It has been widely recognized that depression and PTSD may decrease patients' quality of life. The objective of this study is conducted to explore the effects of p...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000019776

    authors: Lu JY,Tung TH,Shen SA,Huang C,Chen PS

    更新日期:2020-04-01 00:00:00

  • Influence of SIRT1 polymorphisms for diabetic foot susceptibility and severity.

    abstract::The present study aimed to explore the influence of sirtuin 1 (SIRT1) polymorphisms (rs12778366 and rs3758391) on diabetic foot (DF) susceptibility and severity in patients with type 2 diabetes mellitus (T2DM).This case-control study recruited 142 patients with DF, 148 patients with T2DM, and 148 healthy controls. SIR...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011455

    authors: Peng Y,Zhang G,Tang H,Dong L,Gao C,Yang X,Peng Y,Xu Y

    更新日期:2018-07-01 00:00:00

  • Operative versus nonoperative treatment of displaced intra-articular calcaneal fractures: A meta-analysis of current evidence base.

    abstract:BACKGROUND:The relative efficacy of operative and nonoperative treatments for the displaced intra-articular calcaneal fractures (DIACF) remains uncertain. OBJECT:We conducted a meta-analysis to compare the effectiveness of operative and nonoperative treatments in treating patients with DIACF. METHODS:Databases includ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000009027

    authors: Wei N,Yuwen P,Liu W,Zhu Y,Chang W,Feng C,Chen W

    更新日期:2017-12-01 00:00:00

  • Primary epiploic appendagitis as an unusual cause of acute abdominal pain in a middle-aged male: A case report.

    abstract:RATIONALE:Primary epiploic appendagitis (PEA) is a rare cause of acute abdomen caused by spontaneous torsion or venous thrombosis of epiploic appendices, it commonly manifests with acute lower quadrant pain, thus may mimic acute diverticulitis, appendicitis, or mesenteric infarction. PATIENT CONCERNS:In this case repo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016846

    authors: Yang L,Jia M,Han P

    更新日期:2019-08-01 00:00:00

  • Warfarin prevented de novo portal vein thrombosis after transjugular intrahepatic portosystemic shunt: A retrospective study.

    abstract::Portal vein thrombosis (PVT) might impair the prognosis of cirrhotic patients. However, formation of de novo PVT after transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients without preexisting PVT was rarely reported. Moreover, it is not known whether warfarin is efficient in preventing de novo PV...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018737

    authors: Zhang L,Huan H,Tong H,Wei B,Wang Z,Liu C,Wu H

    更新日期:2020-01-01 00:00:00

  • Factors affecting bone age maturation during 3 years of growth hormone treatment in patients with idiopathic growth hormone deficiency and idiopathic short stature: Analysis of data from the LG growth study.

    abstract::To investigate the progression rate of bone age (BA) and associated factors during the first 3 years of growth hormone (GH) treatment in children with idiopathic GH deficiency (iGHD) and idiopathic short stature (ISS).Data for prepubertal children with iGHD and ISS who were treated with recombinant human GH were obtai...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000014962

    authors: Kang MJ,Kim EY,Shim YS,Jeong HR,Lee HJ,Yang S,Hwang IT

    更新日期:2019-04-01 00:00:00

  • Screening key candidate genes and pathways involved in insulinoma by microarray analysis.

    abstract::Insulinoma is a rare type tumor and its genetic features remain largely unknown. This study aimed to search for potential key genes and relevant enriched pathways of insulinoma.The gene expression data from GSE73338 were downloaded from Gene Expression Omnibus database. Differentially expressed genes (DEGs) were ident...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010826

    authors: Zhou W,Gong L,Li X,Wan Y,Wang X,Li H,Jiang B

    更新日期:2018-06-01 00:00:00

  • The clinicopathological factors associated with prognosis of patients with resectable perihilar cholangiocarcinoma: A systematic review and meta-analysis.

    abstract::The refinement in surgical techniques combined with the preoperative management has improved the resectability rate of perihilar cholangiocarcinoma (pCCA). However, the prognosis of pCCA with curative resection is still dismal. This meta-analysis was performed to investigate the prognostic clinicopathological factors ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000011999

    authors: Tang Z,Yang Y,Zhao Z,Wei K,Meng W,Li X

    更新日期:2018-08-01 00:00:00

  • Effectiveness and safety of simeprevir-based regimens for hepatitis C in Italy: The STIly observational study.

    abstract::The combination of the direct-acting antivirals, simeprevir (SMV) and sofosbuvir (SOF), was the first highly efficacious interferon-free combination for treating patients with hepatitis C virus (HCV), and was widely used in Italy as a result.The aim of this study was to evaluate effectiveness and safety of SMV in Ital...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000011307

    authors: Gaeta GB,Aghemo A,Menzaghi B,D'Offizi G,Giorgini A,Hasson H,Brancaccio G,Palma M,Termini R,STIly Study Group.

    更新日期:2018-07-01 00:00:00

  • Folic Acid Intake and Neural Tube Defects: Two Egyptian Centers Experience.

    abstract::Neural tube defects (NTDs) are a group of congenital malformations with worldwide distribution and complex etiopathogenesis. Folic acid plays a pivotal role in their prevention. We aimed to identify the protective effect of folic acid intake against NTDs and its dependence on different socioeconomic and environmental ...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000001395

    authors: El-Shabrawi MH,Kamal NM,Elhusseini MA,Hussein L,Abdallah EAA,Ali YZA,Azab AA,Salama MA,Kassab M,Krawinkel M

    更新日期:2015-09-01 00:00:00

  • Efficacy of herbal medicine (Gegen Qinlian Decoction) on ulcerative colitis: A systematic review of randomized controlled trials.

    abstract:BACKGROUND:This systematic review aims to evaluate the efficacy of Gegen Qinlian Decoction (GQD) for ulcerative colitis (UC). METHODS:PubMed, EMBASE, Springer LINK, Cochrane Library, the China National Knowledge Infrastructure, Chongqing Weipu Database for Chinese Technical Periodicals, Wan-fang Database, and Chinese ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000018512

    authors: Fan Y,Yi W,Huang H,Mei Z,Feng Z

    更新日期:2019-12-01 00:00:00

  • Sudden death due to traumatic ascending aortic pseudoaneurysms ruptured into the esophagus: 2 case reports.

    abstract::We present 2 rare cases of patients with uncontrolled hemorrhagic shock induced by traumatic ascending aortic pseudoaneurysm rupture into the esophagus. Two men were presented to the hospital after traffic accidents. Their chest radiograph showed no obvious signs of aortic damage or aortic pseudoaneurysms but only a s...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000716

    authors: He S,Chen X,Zhou X,Hu Q,Ananda S,Zhu S

    更新日期:2015-04-01 00:00:00

  • Correlation between P-selectin rs1800807 and rs1800808 Gene polymorphisms and plasma soluble P-selectin concentrations in patients with atrial fibrillation complicated with thromboembolism in Xinjiang, China.

    abstract::This study is to investigate the relationship of P-selectin (Ps) gene rs1800807 and rs1800808 polymorphisms with plasma soluble P-selectin (sPs) in Han, Uygur, and Kazakh people with atrial fibrillation (AF) and thromboembolism (TE) in Xinjiang, China.A total of 778 Han patients (including 131 patients with AF and TE,...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018937

    authors: Ma X,Juledezi H,Liu Z,Muhuyati W,Maerjiaen B,He P

    更新日期:2020-01-01 00:00:00

  • Prediction of the outcome of bladder dysfunction based on electrically induced reflex findings in patients with cauda equina syndrome: A retrospective study.

    abstract::The evaluation of the electrically induced bulbocavernosus reflex (BCR) using electromyography (EMG) is a useful tool for evaluating the integrity of sacral spinal segments 2 to 4, and that of their afferent and efferent connections in the urogenital region. In the current retrospective study, the value of this techni...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007014

    authors: Lee DG,Kwak SG,Chang MC

    更新日期:2017-05-01 00:00:00

  • Applicability of ultrasonography for detection of marginal sinus placenta previa.

    abstract:ABSTRACT:This study aimed to examine whether marginal sinus placenta previa, defined as when the marginal sinus just reaches the internal cervical os and placental parenchyma might be >2 cm from the internal cervical os, can be diagnosed using ultrasonography (US). We identified the placenta previa cases that underwent...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000024253

    authors: Ishibashi H,Miyamoto M,Shinmoto H,Soga S,Iwahashi H,Kakimoto S,Matsuura H,Sakamoto T,Hada T,Suzuki R,Takano M

    更新日期:2021-01-08 00:00:00

  • Neutrophil to lymphocyte ratio predicts island sign in patients with intracranial hemorrhage.

    abstract::Our previously studies indicated that inflammatory responses are involved in the hematoma expansion (HE) after intracranial hemorrhage (ICH) ictus. Here, we aim to evaluate the correlations among the ratio of neutrophil to lymphocyte ratio (NLR), HE, and island sign in patients with ICH.Patients with spontaneous ICH w...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013057

    authors: Zhang F,Qian J,Tao C,Wang Y,Lin S,You C,Yang M

    更新日期:2018-11-01 00:00:00

  • A 10-year follow-up study of the association between calcium channel blocker use and the risk of dementia in elderly hypertensive patients.

    abstract::Calcium channel blockers (CCBs) are widely used for reducing blood pressure of hypertensive patients. Recent reports document the beneficial effects of CCB for preventing dementia; however, the results are controversial. We aim to evaluate the risk of developing dementia among elderly hypertensive patients treated wit...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004593

    authors: Wu CL,Wen SH

    更新日期:2016-08-01 00:00:00

  • The aquaporin family of water channel proteins in clinical medicine.

    abstract::The aquaporins are a family of membrane channel proteins that serve as selective pores through which water crosses the plasma membranes of many human tissues and cell types. The sites where aquaporins are expressed implicate these proteins in renal water reabsorption, cerebrospinal fluid secretion and reabsorption, ge...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00005792-199705000-00001

    authors: Lee MD,King LS,Agre P

    更新日期:1997-05-01 00:00:00

  • Distal radius fracture malunion in an adolescent patient treated with osteotomy and autologous iliac bone grafting: A case report.

    abstract:RATIONALE:Adolescent wrist trauma can cause epiphyseal dysplasia and even distal radius deformity malunion. At present, there is no uniform treatment standard for the malunion of the distal radius of adolescents. Osteotomy and autologous bone grafting are currently one of the effective ways to treat the disease. We tre...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022535

    authors: Liu K,Mu L,Liu J,Fu Z,Chen L,Liu B

    更新日期:2020-10-02 00:00:00

  • Clinicopathological significance of cystatin A expression in progression of esophageal squamous cell carcinoma.

    abstract::We previously conducted transcriptome analysis of a paired specimen of normal and esophageal squamous cell carcinoma (ESCC) tissues and found that mRNA expression of cystatin A (CSTA), a member of the cystatin superfamily, was perturbed in tumors compared with that in the background mucosa. However, little is known ab...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010357

    authors: Shiba D,Terayama M,Yamada K,Hagiwara T,Oyama C,Tamura-Nakano M,Igari T,Yokoi C,Soma D,Nohara K,Yamashita S,Dohi T,Kawamura YI

    更新日期:2018-04-01 00:00:00

  • Erratum: The Value of U/S to Determine Priority for Upper Gastrointestinal Endoscopy in Emergency Room: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000002241.]. ...

    journal_title:Medicine

    pub_type: 已发布勘误

    doi:10.1097/01.md.0000479433.86506.88

    authors:

    更新日期:2016-01-08 00:00:00