Analysis of peptide histidine-isoleucine/vasoactive intestinal polypeptide-immunoreactive neurons in the central nervous system with special reference to their relation to corticotropin releasing factor- and enkephalin-like immunoreactivities in the parav

abstract：:In order to examine differential strain susceptibility to neurotoxic effects of amphetamine and to assess the potential role of superoxide radicals in amphetamine-induced dopaminergic damage, the drug was injected to mice with different levels of copper/zinc superoxide dismutase (Cu/Zn SOD) enzyme. Administration of a...

journal_title：Neuroscience

authors： Krasnova IN,Ladenheim B,Jayanthi S,Oyler J,Moran TH,Huestis MA,Cadet JL

更新日期：2001-01-01 00:00:00

abstract：:Distributions of somata and neurites of cholinergic neurons were studied after seeding dissociated cells onto organotypic slice cultures. Slice cultures were made from hippocampal formation and adjacent cortical regions from rats or mice. Dissociated cell suspensions of basal forebrain tissue from rat or mouse fetuses...

journal_title：Neuroscience

authors： Tsai ES,Haraldson SJ,Baratta J,Lander AD,Yu J,Robertson RT

更新日期：2002-01-01 00:00:00

abstract：:Tianeptine (Tian) has been widely used in treating mood and anxiety disorders, and recently as a nootropic to improve cognitive performance. However, its mechanisms of action are insufficiently clear. We used a comparative proteomic approach to identify sub-proteome changes in hippocampal cytosol and non-synaptic mito...

journal_title：Neuroscience

authors： Perić I,Costina V,Findeisen P,Gass P,Filipović D

更新日期：2020-12-15 00:00:00

abstract：:4-Aminopyridine (4-AP) is suggested to improve symptomatology of spinal injury patients because it may facilitate neuromuscular transmission, spinal impulse flow and the operation of the locomotor central pattern generator (CPG). Since 4-AP can also induce repetitive discharges from dorsal root afferents, this phenome...

journal_title：Neuroscience

authors： Taccola G,Nistri A

更新日期：2005-01-01 00:00:00

abstract：:We investigated the electrophysiology of morphologically identified human granule cells with conventional current-clamp recordings. Slices were prepared from 14 human epileptic sclerotic hippocampi. Granule cells appeared to have a diverse electrophysiology. Each cell was distinguished by the shape of the afterhyperpo...

journal_title：Neuroscience

authors： Dietrich D,Clusmann H,Kral T,Steinhäuser C,Blümcke I,Heinemann U,Schramm J

更新日期：1999-01-01 00:00:00

abstract：:Transplantation of embryonic dopaminergic neurons is an experimental therapy for Parkinson's disease, but limited tissue availability and suboptimal survival of grafted dopaminergic neurons impede more widespread clinical application. Glial cell line-derived neurotrophic factor (GDNF) and neurotrophin-4/5 (NT-4/5) exe...

journal_title：Neuroscience

authors： Meyer M,Matarredona ER,Seiler RW,Zimmer J,Widmer HR

更新日期：2001-01-01 00:00:00

abstract：:Corticothalamic axons from layer 5 of primary and secondary auditory and visual areas have large terminals that make multiple synaptic contacts on proximal dendrites of relay cells in higher order thalamic nuclei and have been termed "driver" inputs. The corticothalamic cells express mRNA for the presynaptic growth-as...

journal_title：Neuroscience

authors： Feig SL

更新日期：2005-01-01 00:00:00

abstract：:During rapid cell growth the availability of phospholipid precursors like cytidine triphosphate and diacylglycerol can become limiting in the formation of key membrane constituents like phosphatidylcholine. Uridine, a normal plasma constituent, can be converted to cytidine triphosphate in PC12 [corrected] cells and in...

journal_title：Neuroscience

authors： Pooler AM,Guez DH,Benedictus R,Wurtman RJ

更新日期：2005-01-01 00:00:00

abstract：:Electrophysiological records of unit activity were used to compare the effects of excitotoxic pallidal lesions and 6-hydroxydopamine-induced damage to the midbrain dopaminergic neurons on the discharge rates and patterns of the subthalamic neurons. Removal of the pallidal input induced a slight, but statistically sign...

journal_title：Neuroscience

authors： Hassani OK,Mouroux M,Féger J

更新日期：1996-05-01 00:00:00

abstract：:Exposure to loud, prolonged sounds (acoustic trauma, AT) leads to the death of both inner and outer hair cells (IHCs and OHCs), death of neurons of the spiral ganglion and degeneration of the auditory nerve. The auditory nerve (8cn) projects to the three subdivisions of the cochlear nuclei (CN), the dorsal cochlear nu...

journal_title：Neuroscience

authors： Baizer JS,Wong KM,Manohar S,Hayes SH,Ding D,Dingman R,Salvi RJ

更新日期：2015-09-10 00:00:00

abstract：:How obesity exacerbates migraine and other pain disorders remains unknown. Trigeminal nociceptive processing, crucial in migraine pathophysiology, is abnormal in mice with diet induced obesity. However, it is not known if this is also true in genetic models of obesity. We hypothesized that obese mice, regardless of th...

journal_title：Neuroscience

authors： Rossi HL,Raj NR,Marquez de Prado B,Kuburas A,Luu AKS,Barr GA,Recober A

更新日期：2019-09-01 00:00:00

abstract：:In an attempt to improve the survival of implanted dopamine cells, we have readdressed the optimal embryonic donor age for dopamine grafts. In a rat model of Parkinson's disease, animals with unilateral 6-hydroxydopamine lesions of the median forebrain bundle received dopamine-rich ventral mesencephalic grafts derived...

journal_title：Neuroscience

authors： Torres EM,Monville C,Gates MA,Bagga V,Dunnett SB

更新日期：2007-06-08 00:00:00

abstract：:In the present study we have used the detection of Fos, the protein product of c-fos, to determine the distribution of neurons in the medulla and hypothalamus that are activated by changes in central blood volume. Experiments were conducted in both barointact and barodenervated conscious rabbits, to determine the cont...

journal_title：Neuroscience

authors： Potts PD,Ludbrook J,Gillman-Gaspari TA,Horiuchi J,Dampney RA

更新日期：2000-01-01 00:00:00

abstract：:Animal studies have revealed that chronic stress shifts cognitive strategies from the flexible goal-directed action to the simple and rigid habit action. In addition, stress-induced atrophy in the prefrontal cortex and dorsomedial striatum which are involved in the goal-directed action and hypertrophy of the dorsolate...

journal_title：Neuroscience

authors： Ohira H,Matsunaga M,Kimura K,Murakami H,Osumi T,Isowa T,Fukuyama S,Shinoda J,Yamada J

更新日期：2011-10-13 00:00:00

abstract：:Hippocampal cell firing in awake, behaving rats is often spatially selective, and such cells have been called place cells. Similar spatial correlates have also been described for neurons in the medial entorhinal and perirhinal cortices. All three regions receive sensory associational input from postrhinal cortex, whic...

journal_title：Neuroscience

authors： Burwell RD,Hafeman DM

更新日期：2003-01-01 00:00:00

abstract：:GABA(A) functioning has been implicated in anxiety and depressive disorders. In this regard, we suggested that in addition to analyzing GABA(A) and the subunits that comprise the GABA(A) receptor, it might be profitable to assess the coordinated expression of subunits that comprise the GABA(A) receptor cassette. We de...

journal_title：Neuroscience

authors： Poulter MO,Du L,Zhurov V,Merali Z,Anisman H

更新日期：2010-02-17 00:00:00

abstract：:Intracellular stimulation of single propriospinal axons evoked excitatory postsynaptic potentials (EPSPs) in lumbar motoneurons. Mean EPSP amplitudes differed by two orders of magnitude when measured in different connections. After analyzing the distribution of mean amplitudes of 47 single-fiber EPSPs, two populations...

journal_title：Neuroscience

authors： Dityatev A,Birinyi A,Puskár Z,Antal M,Clamann HP

更新日期：2001-01-01 00:00:00

abstract：:Developmental changes in ganglioside levels and patterns were investigated in neuronal cells dissociated from 17-day-old fetal rat hemispheres for up to 7 days of culture. Increases in ganglioside contents and the onset of GM3 synthesis, which is associated with proliferation of glial cells, were observed as the neuro...

journal_title：Neuroscience

authors： Ogiso M,Ohta M,Harada Y,Kubo H,Hirano S

更新日期：1991-01-01 00:00:00

abstract：:Glutamate transporter-1 (GLT-1) is responsible for the largest proportion of glutamate transport in the brain and the density of GLT-1 molecules inserted in the plasma membrane is highest in regions of high demand. Previous electron microscopic studies in the hippocampus and cerebellum have shown that GLT-1 is concent...

journal_title：Neuroscience

authors： Minelli A,Barbaresi P,Reimer RJ,Edwards RH,Conti F

更新日期：2001-01-01 00:00:00

abstract：:Physiological and anatomical investigations are commonly combined in experimental models. When studying the lower urinary tract (LUT), it is often of interest to perform both urodynamic studies and retrogradely labeled neurons innervating the peripheral target organs. However, it is not known whether the use of anatom...

journal_title：Neuroscience

authors： Chang HY,Havton LA

更新日期：2010-03-10 00:00:00

abstract：:Rats exposed to repeated unavoidable stress show decreased dopamine output in the nucleus accumbens shell (NAcS) and do not acquire vanilla sugar (VS)-sustained appetitive behavior (VAB). Rats treated with lithium for 3 weeks also show decreased NAcS dopamine output, yet they acquire VAB. Feeding a novel palatable foo...

journal_title：Neuroscience

authors： Gambarana C,Masi F,Leggio B,Grappi S,Nanni G,Scheggi S,De Montis MG,Tagliamonte A

更新日期：2003-01-01 00:00:00

abstract：:Androgens are known to affect cognitive and mnemonic aspects of spatial processing. The cholinergic system is thought to play an important role in cognition and memory, but little is known about the interaction between androgen and cholinergic neurons. The present study focused on the effects of testosterone on the ch...

journal_title：Neuroscience

authors： Nakamura N,Fujita H,Kawata M

更新日期：2002-01-01 00:00:00

abstract：:Increased levels of preproenkephalin mRNA in spinal cord neurons induced by peripheral tissue inflammation were examined using in situ hybridization histochemistry. In addition, in situ hybridization histochemistry was combined with immunocytochemistry to determine whether increases in preproenkephalin mRNA were co-lo...

journal_title：Neuroscience

authors： Noguchi K,Dubner R,Ruda MA

更新日期：1992-01-01 00:00:00

abstract：:The pontine projection of the flocculus and adjacent ventral paraflocculus was investigated with antegrade and retrograde axonal tracer techniques. Injections of horseradish peroxidase into the floccular complex revealed subsets of labeled neurons in the nucleus reticularis tegmenti pontis, the nucleus raphe pontis an...

journal_title：Neuroscience

authors： Gerrits NM,Epema AH,Voogd J

更新日期：1984-03-01 00:00:00

abstract：:Dopamine is a neurotransmitter crucial for motor, motivational, and reward-related functions. Our aim was to determine the effect of a palatable maternal diet on the transcriptional regulation of dopaminergic-related genes during perinatal development of rat offspring. For that, female offspring from dams fed with a c...

journal_title：Neuroscience

authors： Rossetti MF,Schumacher R,Gastiazoro MP,Lazzarino GP,Andreoli MF,Stoker C,Varayoud J,Ramos JG

更新日期：2020-01-01 00:00:00

abstract：:The intracochlear infusion of neurotrophic factors via a mini-osmotic pump has been shown to prevent deafness-induced spiral ganglion neuron (SGN) degeneration; however, the use of pumps may increase the incidence of infection within the cochlea, making this technique unsuitable for neurotrophin administration in a cl...

journal_title：Neuroscience

authors： Pettingill LN,Minter RL,Shepherd RK

更新日期：2008-03-27 00:00:00

abstract：:Stimulus-induced pattern of bioelectric activity in human neocortical tissue was investigated by use of the voltage sensitive dye RH795 and a fast optical recording system. During control conditions stimulation of layer I evoked activity predominantly in supragranular layers showing a spatial extent of up to 3000 micr...

journal_title：Neuroscience

authors： Straub H,Kuhnt U,Höhling JM,Köhling R,Gorji A,Kuhlmann D,Tuxhorn I,Ebner A,Wolf P,Pannek HW,Lahl R,Speckmann EJ

更新日期：2003-01-01 00:00:00

abstract：:In the enteric nervous system, acetylcholine is the most common neurotransmitter to induce gastrointestinal smooth muscle contractions. Cholinergic signaling is mediated by muscarinic acetylcholine receptors on the surface of smooth muscle cells. Five different muscarinic receptor subtypes (M(1)-M(5)) have been identi...

journal_title：Neuroscience

authors： Iino S,Nojyo Y

更新日期：2006-01-01 00:00:00

abstract：:Previous studies have shown the feasibility of using diffusion tensor imaging (DTI) as a noninvasive imaging modality to evaluate neurodegeneration in humans and animals. The axial and radial diffusivities derived from DTI were demonstrated to be sensitive markers for axonal and myelin damage, respectively. This study...

journal_title：Neuroscience

authors： Xie M,Wang Q,Wu TH,Song SK,Sun SW

更新日期：2011-12-01 00:00:00

abstract：:Monoamine oxidase, monoamine oxidase-A, and monoamine oxidase-B activities were compared in free moving, rapid eye movement sleep-deprived, recovered, and control rat brains. The activities were estimated in the whole brain, cerebrum, cerebellum, whole brainstem, medulla, pons, and midbrain. The flowerpot method was u...

journal_title：Neuroscience

authors： Thakkar M,Mallick BN

更新日期：1993-08-01 00:00:00