Ontogenetic changes in the body plan of the sauropodomorph dinosaur Mussaurus patagonicus reveal shifts of locomotor stance during growth.

abstract：:The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding the SMYD1 promoter, participates in various cellular processes and is involved in human cancers. We report the first crystal structures of the human HDGF PWWP domain (residues 1-100) in a comp...

journal_title：Scientific reports

authors： Chen LY,Huang YC,Huang ST,Hsieh YC,Guan HH,Chen NC,Chuankhayan P,Yoshimura M,Tai MH,Chen CJ

更新日期：2018-01-10 00:00:00

abstract：:Maritime ecosystems in Vietnam such as mangroves and mud flats are characterized by high biodiversity. However, elements of its biodiversity remain unclear and highly threatened. In this context, the assessment of rare species is a starting point to develop effective strategies for the conservation of entire ecosystem...

journal_title：Scientific reports

authors： Saito T,Prozorova L,Quang NX,Chiba S

更新日期：2020-10-30 00:00:00

abstract：:Anti-cytokine therapeutic antibodies have been demonstrated to be effective in the treatment of several auto-immune disorders. However, The problems in antibody manufacture and the immunogenicity caused by multiple doses of antibodies inspire people to use auto-cytokine as immunogen to induce anti-cytokine antibodies....

journal_title：Scientific reports

authors： Liu C,Zhao Y,He W,Wang W,Chen Y,Zhang S,Ma Y,Gohda J,Ishida T,Walter TS,Owens RJ,Stuart DI,Ren J,Gao B

更新日期：2015-09-28 00:00:00

abstract：:Spin-coated self-assemblies of colloidal particles have been developed recently as an attractive close-packed monolayer of the particles for a variety of applications, but they are limited by the small area of their monolayers, especially given their low uniformity and monolayer coverage on large-area substrates. We r...

journal_title：Scientific reports

authors： Park B,Na SY,Bae IG

更新日期：2019-08-07 00:00:00

abstract：:Molecular alignment underpins optical, mechanical, and thermal properties of materials, however, its direct measurement from volumes with micrometer dimensions is not accessible, especially, for structurally complex bio-materials. How the molecular alignment is linked to extraordinary properties of silk and its amorph...

journal_title：Scientific reports

authors： Ryu M,Balčytis A,Wang X,Vongsvivut J,Hikima Y,Li J,Tobin MJ,Juodkazis S,Morikawa J

更新日期：2017-08-07 00:00:00

abstract：:Inflammatory and cardiovascular biomarkers have been associated with obesity, but little is known about how they change upon dietary intervention and concomitant weight loss. Further, protein biomarkers might be useful for predicting weight loss in overweight and obese individuals. We performed secondary analyses in t...

journal_title：Scientific reports

authors： Figarska SM,Rigdon J,Ganna A,Elmståhl S,Lind L,Gardner CD,Ingelsson E

更新日期：2020-05-13 00:00:00

abstract：:The myxozoan parasite, Tetracapsuloides bryosalmonae has a two-host life cycle alternating between freshwater bryozoans and salmonid fish. Infected fish can develop Proliferative Kidney Disease, characterised by a gross lymphoid-driven kidney pathology in wild and farmed salmonids. To facilitate an in-depth understand...

journal_title：Scientific reports

authors： Faber M,Shaw S,Yoon S,de Paiva Alves E,Wang B,Qi Z,Okamura B,Hartikainen H,Secombes CJ,Holland JW

更新日期：2021-01-25 00:00:00

abstract：:Patients with Idiopathic Parkinson's Disease (PD) have an increased risk for fractures. Currently, many studies have reported inferior outcomes in PD patients after orthopedic procedures. However, there are very few studies assessing the outcome of upper extremity fractures (UEF) in PD patients. In this study, we revi...

journal_title：Scientific reports

authors： Chou TA,Chang CY,Wang JP,Huang YC,Chen WM,Huang TF

更新日期：2020-12-03 00:00:00

abstract：:Dissecting the complex molecular interplay between the host plant and invading virus improves our understanding of the mechanisms underlying viral pathogenesis. In this study, immunoprecipitation together with the mass spectrometry analysis revealed that the heat shock protein 70 (Hsp70) family homolog, Hsc70-2, was c...

journal_title：Scientific reports

authors： Wang X,Cao X,Liu M,Zhang R,Zhang X,Gao Z,Zhao X,Xu K,Li D,Zhang Y

更新日期：2018-03-14 00:00:00

abstract：:Colorectal cancer (CRC) is a cancer of growing incidence that associates with a high mortality rate worldwide. There is a poor understanding of the heterogeneity of CRC with regard to causative genetic mutations and gene regulatory mechanisms. Previous studies have identified several susceptibility genes in small-scal...

journal_title：Scientific reports

authors： Zhao M,Liu Y,Huang F,Qu H

更新日期：2016-08-01 00:00:00

abstract：:Vitellogenesis or maternal yolk formation is considered critical to the reproduction of egg-laying animals. In invertebrates, however, most of its regulatory genes are still unknown. Via a combined mapping and whole-genome sequencing strategy, we performed a forward genetic screen to isolate novel regulators of yolk p...

journal_title：Scientific reports

authors： Van Rompay L,Borghgraef C,Beets I,Caers J,Temmerman L

更新日期：2015-11-10 00:00:00

abstract：:The AMP-activated kinase (AMPK) is a major energy sensor metabolic enzyme that is activated early during T cell immune responses but its role in the generation of effector T cells is still controversial. Using both in vitro and in vivo models of T cell proliferation, we show herein that AMPK is dispensable for early T...

journal_title：Scientific reports

authors： Lepez A,Pirnay T,Denanglaire S,Perez-Morga D,Vermeersch M,Leo O,Andris F

更新日期：2020-12-10 00:00:00

abstract：:In this work, we address the ubiquitous phenomenon of Fano resonances in bilayer graphene. We consider that this phenomenon is as exotic as other phenomena in graphene because it can arise without an external extended states source or elaborate nano designs. However, there are not theoretical and/or experimental studi...

journal_title：Scientific reports

authors： Briones-Torres JA,Rodríguez-Vargas I

更新日期：2017-12-01 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Nakagawa A,Naito AT,Sumida T,Nomura S,Shibamoto M,Higo T,Okada K,Sakai T,Hashimoto A,Kuramoto Y,Oka T,Lee JK,Harada M,Ueda K,Shiojima I,Limbourg FP,Adams RH,Noda T,Sakata Y,Akazawa H,Komuro I

更新日期：2018-10-29 00:00:00

abstract：:Cardiac magnetic resonance (CMR) is becoming the imaging modality of choice in multicenter studies where highly reproducible measurements are necessary. The purpose of this study was to assess the effect of comprehensive initial training on reproducibility of quantitative left ventricular (LV) parameters estimated usi...

journal_title：Scientific reports

authors： Lapinskas T,Hireche-Chikaoui H,Zieschang V,Erley J,Stehning C,Gebker R,Giusca S,Korosoglou G,Zaliunas R,Backhaus SJ,Schuster A,Pieske B,Kelle S

更新日期：2019-08-21 00:00:00

abstract：:We aimed to model longitudinal data to create predictive growth charts for weight in preterm infants from birth till discharge, that took into account the differing growth rates post-birth when compared to in-utero growth and therefore was more representative of the data than the UK1990 reference charts. Data from bir...

journal_title：Scientific reports

authors： Watkins WJ,Farewell D,Banerjee S,Nasef H,James A,Chakraborty M

更新日期：2020-03-04 00:00:00

abstract：:Cold atmospheric plasma (CAP), a technology based on quasi-neutral ionized gas at low temperatures, is currently being evaluated as a new highly selective alternative addition to existing cancer therapies. Here, we present a first attempt to identify the mechanism of CAP action. CAP induced a robust ~2-fold G2/M incre...

journal_title：Scientific reports

authors： Volotskova O,Hawley TS,Stepp MA,Keidar M

更新日期：2012-01-01 00:00:00

abstract：:Southern rice black-streaked dwarf virus (SRBSDV), a newly emerged fijivirus causing great loss to rice production in eastern and southeastern Asian countries in recent years, is efficiently transmitted by a rice pest, white-backed planthopper (WBPH, Sogatella furcifera) in a persistent, circulative propagative manner...

journal_title：Scientific reports

authors： Xu D,Zhong T,Feng W,Zhou G

更新日期：2016-08-17 00:00:00

abstract：:We show that the width of an arbitrary function and the width of the distribution of its values cannot be made arbitrarily small simultaneously. In the case of ergodic stochastic processes, an ensuing uncertainty relationship is then demonstrated for the product of correlation length and variance. A closely related un...

journal_title：Scientific reports

authors： Gureyev TE,Kozlov A,Paganin DM,Nesterets YI,Quiney HM

更新日期：2020-05-12 00:00:00

abstract：:The toxicological mechanisms of liver injury caused by most traditional Chinese medicine (TCM) remain largely unknown. Due to the unique features, exosomal microRNAs (miRNAs) are currently attracting major interests to provide further insights into toxicological mechanisms. Thus, taking Fructus Meliae Toosendan as an ...

journal_title：Scientific reports

authors： Zheng J,Yu L,Chen W,Lu X,Fan X

更新日期：2018-02-12 00:00:00

abstract：:An on-going debate concerning the dietary adaptations of archaic hominins and early Homo has been fuelled by contradictory inferences obtained using different methodologies. This work presents an extensive comparative sample of 30 extant primate species that was assembled to perform a morpho-functional comparison of t...

journal_title：Scientific reports

authors： Marcé-Nogué J,Püschel TA,Daasch A,Kaiser TM

更新日期：2020-04-22 00:00:00

abstract：:Demand for clinical decision support systems in medicine and self-diagnostic symptom checkers has substantially increased in recent years. Existing platforms rely on knowledge bases manually compiled through a labor-intensive process or automatically derived using simple pairwise statistics. This study explored an aut...

journal_title：Scientific reports

authors： Rotmensch M,Halpern Y,Tlimat A,Horng S,Sontag D

更新日期：2017-07-20 00:00:00

abstract：:The preferential degeneration of Substantia nigra dopamine midbrain neurons (SN DA) causes the motor-symptoms of Parkinson's disease (PD). Voltage-gated L-type calcium channels (LTCCs), especially the Cav1.3-subtype, generate an activity-related oscillatory Ca(2+) burden in SN DA neurons, contributing to their degener...

journal_title：Scientific reports

authors： Poetschke C,Dragicevic E,Duda J,Benkert J,Dougalis A,DeZio R,Snutch TP,Striessnig J,Liss B

更新日期：2015-09-18 00:00:00

abstract：:The high density nucleation of α-Al2O3 nanocrystallites was observed by rapid heating of the aluminum formate hydroxide-based precursor powder at 1200 °C for 50 s. The nucleation of α-Al2O3 nanocrystallites with less 10 nm in size from high purity aluminum oxide matrix has not been observed to our knowledge. Based on ...

journal_title：Scientific reports

authors： Yoshida M,Kato Y,Oumi Y,Sakurada O,Tanaka M,Wada M,Kitaoka S

更新日期：2019-10-17 00:00:00

abstract：:Vocal expression of emotions has been suggested to be conserved throughout evolution. However, since vocal indicators of emotions have never been compared between closely related species using similar methods, it remains unclear whether this is the case. Here, we investigated vocal indicators of emotional valence (neg...

journal_title：Scientific reports

authors： Maigrot AL,Hillmann E,Anne C,Briefer EF

更新日期：2017-08-18 00:00:00

abstract：:To understand the mechanism controlling cultivar differences in the accumulation of ciprofloxacin (CIP) in Chinese flowering cabbage (Brassica parachinensis L.), low-molecular-weight organic acids (LMWOAs) secreted from the roots of high- and low-CIP cultivars (Sijiu and Cutai, respectively) and their effects on the b...

journal_title：Scientific reports

authors： Zhao HM,Xiang L,Wu XL,Jiang YN,Li H,Li YW,Cai QY,Mo CH,Liu JS,Wong MH

更新日期：2017-08-31 00:00:00

abstract：:Many scientists are seeking better therapies for treating fibromyalgia (FM) pain. We used a mouse model of FM to determine if ASIC3 and its relevant signaling pathway participated in FM pain. We demonstrated that FM-induced mechanical hyperalgesia was attenuated by electroacupuncture (EA). The decrease in fatigue-indu...

journal_title：Scientific reports

authors： Yen LT,Hsieh CL,Hsu HC,Lin YW

更新日期：2017-04-25 00:00:00

abstract：:Allergic contact hypersensitivity (CHS) is an inflammatory skin disease mediated by allergen specific T cells. In this study, we investigated the role of transcription factor NFAT1 in the pathogenesis of contact hypersensitivity. NFAT1 knock out (KO) mice spontaneously developed CHS-like skin inflammation in old age. ...

journal_title：Scientific reports

authors： Kwon HK,Kim GC,Hwang JS,Kim Y,Chae CS,Nam JH,Jun CD,Rudra D,Surh CD,Im SH

更新日期：2016-01-18 00:00:00

abstract：:Hepatitis C virus (HCV) has long been observed to take advantage of the host mitochondria to support viral replication and assembly. The HCV core protein has been implicated to fragment host mitochondria. In this report, we have discovered that the non-structural protein 5A (NS5A) plays an instructive role in attachin...

journal_title：Scientific reports

authors： Siu GK,Zhou F,Yu MK,Zhang L,Wang T,Liang Y,Chen Y,Chan HC,Yu S

更新日期：2016-03-24 00:00:00

abstract：:The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate. Our study aims to identify its progression from the preoperative MR radiomics. 57 newly diagnosed cerebral glioblastoma patients were ...

journal_title：Scientific reports

authors： Yan JL,Li C,van der Hoorn A,Boonzaier NR,Matys T,Price SJ

更新日期：2020-06-16 00:00:00