Abstract:
:Medications should be used with caution in women of childbearing age who are pregnant, or are contemplating pregnancy. Although topical medications are considered safer than oral or parenteral agents, their safety data in pregnancy must be assessed carefully. The available information on medication use in pregnancy is limited, and not always aided by the FDA pregnancy letter category system. Thus, in this article, we aggregate human studies, animal studies, and pharmacokinetics data to provide recommendations on utilizing topical antibiotics in pregnancy.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Patel VM,Schwartz RA,Lambert WCdoi
10.1111/dth.12951subject
Has Abstractpub_date
2019-07-01 00:00:00pages
e12951issue
4eissn
1396-0296issn
1529-8019journal_volume
32pub_type
杂志文章,评审abstract::Hair's importance in human communication means that abnormalities like excess hair in hirsutism or hair loss in alopecia cause psychological distress. Androgens are the main regulator of human hair follicles, changing small vellus follicles producing tiny, virtually invisible hairs into larger intermediate and termina...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2008.00214.x
更新日期:2008-09-01 00:00:00
abstract::Minimally ablative fractional laser devices have gained acceptance as a preferred method for skin resurfacing. Notable improvements in facial rhytides, photodamage, acne scarring, and skin laxity have been reported. The aim of the present work was to compare how different CO(2) laser fluences, by modulating the secret...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1529-8019.2009.01265.x
更新日期:2009-11-01 00:00:00
abstract::Psoriasis is associated with an increased risk of atherosclerosis. The objective of this study is evaluate the relationship between carotid intima-media thickness (CIMT) serum and cystatin-C, fetuin-A levels in determining the increased risk of subclinical atherosclerosis in psoriasis patients. In this study, age and ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13898
更新日期:2020-11-01 00:00:00
abstract::Photodermatoses can be classified into five general categories: 1) idiopathic photodermatoses, including polymorphic light eruption (PMLE), actinic prurigo, hyroa vacciniforme, chronic actinic dermatitis, and solar urticaria; 2) photodermatoses which are secondary to exogenous agents, including phototoxic and photoall...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1046/j.1529-8019.2003.01601.x
更新日期:2003-01-01 00:00:00
abstract::Vitiligo progression is attributed to immune system malfunctioning, thus immunomodulating compounds might be beneficial in stopping vitiligo progression which is a prerequisite for successful repigmentation. The goal of this study was to assess efficacy of acridone acetic acid, sodium salt (Na-AAA), an immunomodulatin...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/dth.12121
更新日期:2014-07-01 00:00:00
abstract::Dermoscopy as a diagnostic tool is attaining impetus in inflammatory dermatoses with the cumulative description of characteristic findings in most dermatoses obviating at times the need of biopsy. In this retrospective observational study, 20 histopathology confirmed cases each of pityriasis rosea (PR), guttate psoria...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14631
更新日期:2020-12-05 00:00:00
abstract::Covering wounds, acute and chronic, is one of the most fundamental activities of any medical practitioner. Although wound dressings primarily serve to contain the "good" and keep out the "bad," research has characterized more specifically the sophisticated interaction between the human wound bed and its dressing count...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12055
更新日期:2013-05-01 00:00:00
abstract::Reflectance confocal microscopy (RCM) enables the noninvasive in vivo imaging of the skin with a horizontal axis and a cellular-level resolution allowing the study of the skin from superficial layers to papillary dermis. It has arisen an important tool in the study of tumors and specially an important role in the char...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2012.01495.x
更新日期:2012-09-01 00:00:00
abstract::Several treatment modalities are used for the treatment of acne scars with variable results. Recent studies showed that fractional radiofrequency may be an effective treatment modality for acne scars. The objective of this study was to assess the efficacy, safety, tolerability and patient satisfaction of fractional bi...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/dth.12275
更新日期:2016-01-01 00:00:00
abstract::The reported efficacy of various treatments for alopecia is difficult to compare based on a general lack of consideration in case reports/series and clinical trials of the spontaneous regrowth or baseline prognostic factors seen in alopecia areata and a general lack of quantification of hair growth. This report will g...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2011.01415.x
更新日期:2011-05-01 00:00:00
abstract::Acrodermatitis continua of Hallopeau (ACH) is a chronic, inflammatory, and relapsing disorder characterized by the progressive destruction of fingernails and toenails. This condition is rare, difficult to treat, and often misdiagnosed. Several antipsoriatic treatments have been used, without any therapeutic guideline ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12946
更新日期:2019-07-01 00:00:00
abstract::Tumor necrosis-alpha (TNF-alpha) has been implicated in many forms of inflammation and is an end-stage product of the inflammatory cytokine cascade. It is an inducer of inflammation and is involved in many cutaneous and systemic inflammatory diseases. The development of agents that block the effects of TNF-alpha has a...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2007.00138.x
更新日期:2007-07-01 00:00:00
abstract::Successful treatment of Hailey-Hailey disease with intradermal botulinum toxin injections has been previously reported. The main disadvantages of this treatment are the excruciating pain and the risk of infections due to the numerous injections. We sought to evaluate the clinical effectiveness and safety profile of a ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13184
更新日期:2020-01-01 00:00:00
abstract::COVID-19 disease is a highly contagious and particularly popular problem in all countries. A variety of repurposed drugs and investigational drugs such as remdesivir, chloroquine, hydroxychloroquine, ritonavir, lopinavir, interferon-beta, and other potential drugs have been studied for COVID19 treatment. We reviewed t...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13476
更新日期:2020-07-01 00:00:00
abstract::Solid organ transplant recipients are at a significantly increased risk of developing skin cancer. Both systemic and topical retinoids are useful for chemosuppression of skin cancer in this patient population. These drugs can reduce both the present extent and the future development of premalignant and malignant skin ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2005.05006.x
更新日期:2005-01-01 00:00:00
abstract::Scleredema is a deposition disorder which presents as diffuse, symmetric, non-pitting skin induration from dermal deposits of glycosaminoglycans ("mucins"). It classically affects the upper back and posterior neck, often causing skin tightness and decreased range of motion. In most patients the clinical course is chro...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12504
更新日期:2017-07-01 00:00:00
abstract::Filiform warts are commonly treated with surgical removal or cryotherapy, yet such treatment modalities may result in complications for darker skin types. We report a man successfully treated for more than 50 filiform facial warts using a combination of 5-fluorouracil 5% and salicylic acid 20%. ...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.13235
更新日期:2020-03-01 00:00:00
abstract::Vitiligo is a systemic disease that affects not only the skin but also other areas that contain melanocytes, such as the inner ear. Studies of the effect of vitiligo on hearing loss have shown inconsistent results, and it is not clear which parameters related to the disease affect hearing. The aim of this study was to...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13724
更新日期:2020-07-01 00:00:00
abstract::Psoriasis is a chronic, systemic inflammatory disease that in the moderate to severe forms may benefit of biologics, namely TNF and IL-12/23 and IL-17 inhibitors. Loss of response, lack of response, or discontinuation due to adverse events represent a concrete therapeutic challenge for dermatologists that have to swit...
journal_title:Dermatologic therapy
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/dth.12793
更新日期:2019-03-01 00:00:00
abstract::The world is facing a viral pandemic of a new coronavirus called COVID-19. Pentoxifylline is a methyl-xanthine derivative and it inhibits the phosphodiesterase IV (PDE IV). This drug is known for its unique features as an immunomodulatory and anti-inflammatory agent, also it could have antiviral affects. This is a sco...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13733
更新日期:2020-07-01 00:00:00
abstract::Eccrine porocarcinoma (EPC) is a rare cutaneous neoplasm that grows slowly over a long period of time but often experiences an accelerated growth phase. This malignant tumor may arise denovo or evolve from a pre-existing benign eccrine poroma. Histologic evaluation demonstrates anaplastic cells involving the epidermis...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2008.00243.x
更新日期:2008-11-01 00:00:00
abstract::Cyclosporine A (CYA) belongs to calcineurin inhibitor family, which has the ability to selectively suppress T cells. Owing to its immune-modulatory effects, it had been in use for graft vs host diseases and organ transplant rejection for many years, but in dermatology, it was first approved for use in 1997 in the trea...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13934
更新日期:2020-11-01 00:00:00
abstract::In view of the new viral COVID-19 pandemic, the fungal Candida auris epidemic still in progress worldwide highlights non-Candida albicans candidal infections. We describe an immunocompetent woman with a cutaneous manifestation of Candida parasilopsis fungemia, a prominent eschar, which proved to be the nidus for the c...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13481
更新日期:2020-07-01 00:00:00
abstract::Studies on microcystic adnexal carcinoma (MAC) survival rates have been limited. This effort examines the association of patient demographics, treatment modalities, and tumor stage with overall survival (OS) in patients with MAC of the head and neck. All cases of MAC with primary sites of the skin of the head and neck...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14559
更新日期:2020-11-18 00:00:00
abstract::Psoriasis is a chronic inflammatory disease of the skin which can occur at any age-group. Psoriasis in childhood is not uncommon and has genetic susceptibility but usually, an environmental trigger such as infection is thought to initiate the disease process. Pediatric psoriasis has profound effects on both physical a...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12571
更新日期:2018-01-01 00:00:00
abstract::Psoriasis is a chronic skin inflammatory disorder with frequent relapse. Ceramides and their key enzymes are deficient in the lesions, resulting in impaired epidermal permeability barrier, which correlates with disease severity. We evaluated the efficacy of linoleic acid-ceramide moisturizer (LA-Cer) as an adjunctive ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,随机对照试验
doi:10.1111/dth.12259
更新日期:2015-11-01 00:00:00
abstract::For effective treatment of vitiligo, it is as important to arrest the progression of the disease, as it is to induce repigmentation. Epidermal oxidative stress has been documented in vitiligo patients, and there is much support for a free-radical-mediated damage as an initial pathogenic event in melanocyte degeneratio...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1529-8019.2010.01328.x
更新日期:2010-05-01 00:00:00
abstract::Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00164.x
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To explore the inhibition of the proliferation of vulvar squamous cell carcinoma (VSCC) by astragaloside IV. METHODS:MTT examined the cell proliferation of VSCC. Flow cytometry analyzed cell cycle and apoptosis. Western blot assay detected the expression of some relevant proteins. RESULTS:AS-IV reduced the ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12802
更新日期:2019-07-01 00:00:00
abstract::Hydrogels based on hyaluronic acid are used to restore volume, hydration, and skin tone, as well as to correct scars, asymmetries or defects of the soft tissue. Hyaluronic acid is often chemically crosslinked with different crosslinking agents in order to improve its mechanical and biological properties. Here we focus...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13747
更新日期:2020-07-01 00:00:00