Macular ganglion cell complex parameters by optical coherence tomography in cases of multiple sclerosis without optic neuritis compared to healthy eyes.

Abstract:

Purpose:To compare different macular thickness parameters and peripapillary retinal nerve fiber layer (RNFL) thickness between recently diagnosed cases of multiple sclerosis (MS) without optic neuropathy (ON) and healthy individuals. Methods:This cross-sectional study was performed between June 2014 and June 2015. All subjects underwent ocular and retinal examination. Spectral domain optical coherence tomography (SD-OCT) was used to measure the thickness of different layers of the retina at macular and peripapillary regions and at different quadrants. Between groups comparison was performed with P < 0.05 indicating statistical significance. Results:There were 32 eyes in the MS group and 74 eyes in the control group. The MS group was significantly younger than the control group (P < 0.001). The mean ganglion cell complex (GCL++) thickness in superior macular area was 64.1 ± 8.9 μ in the MS group and 71.1 ± 5.9 μ in the control group. The thickness of the RNFL did not statistically differ in each of the quadrants between groups. Despite controlling for age, the macular thickness parameters were significantly thinner in eyes with MS compared to healthy eyes (P < 0.01). Conclusion:The macular ganglion cell complex (mGCC) parameters were significantly reduced in recently diagnosed cases of MS as compared to healthy individuals.

journal_name

Indian J Ophthalmol

authors

Lotfy NM,Alasbali T,Khandekar R

doi

10.4103/ijo.IJO_1378_18

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

648-653

issue

5

eissn

0301-4738

issn

1998-3689

pii

IndianJOphthalmol_2019_67_5_648_256664

journal_volume

67

pub_type

杂志文章
  • The International Council of Ophthalmology Ophthalmic clinical evaluation exercise.

    abstract:Purpose:Fifteen years after the publication of the Ophthalmic Clinical Evaluation Exercise (OCEX), it was deemed necessary to review and revise it, and to validate it for an international audience of ophthalmologists. This study to revise the OCEX and validate it for international use. Methods:The OCEX rubric was chan...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_154_20

    authors: Palis AG,Barrio-Barrio J,Mayorga EP,Mili-Boussen I,Noche CD,Swaminathan M,Golnik KC

    更新日期:2021-01-01 00:00:00

  • Outcomes of deep anterior lamellar keratoplasty following autologous simple limbal epithelial transplant in pediatric unilateral severe chemical injury.

    abstract:AIMS:To evaluate outcomes of deep anterior lamellar keratoplasty (DALK) in pediatric eyes with unilateral severe chemical injury which have undergone autologous simple limbal epithelial transplant (SLET). SETTINGS AND DESIGN:The study design was a retrospective case series. MATERIALS AND METHODS:This retrospective, c...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_880_16

    authors: Singh D,Vanathi M,Gupta C,Gupta N,Tandon R

    更新日期:2017-03-01 00:00:00

  • Intraocular biopsy in uveitis.

    abstract::An intraocular biopsy is performed for diagnostic, prognostic and investigational purposes. Biopsies help to confirm or exclude malignancies and differentiate inflammatory from infectious processes. Histopathological analysis is the final verdict in unresponsive uveitis, atypical inflammation, metastases and masquerad...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.4103/ijo.IJO_1325_20

    authors: Patnaik G,Annamalai R,Biswas J

    更新日期:2020-09-01 00:00:00

  • Paradoxical worsening of a case of TB subretinal abscess with serpiginous-like choroiditis following the initiation of antitubercular therapy.

    abstract::A 37-year-old immunocompetent male patient presented with the blurring of vision, both eyes for the past1 year. Fundus examination revealed bilateral multiple subretinal abscesses with areas of healed serpiginous-like choroiditis. Laboratory investigations showed positive tuberculin skin test, positive QuantiFERON TB-...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_184_17

    authors: Ganesh SK,Ali BS

    更新日期:2017-08-01 00:00:00

  • Non-contact lens related Acanthamoeba keratitis.

    abstract::The purpose of the study is to describe epidemiology, clinical features, diagnosis, and treatment of Acanthamoeba keratitis (AK) with special focus on the disease in nonusers of contact lenses (CLs). This study was a perspective based on authors' experience and review of published literature. AK accounts for 2% of mic...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.4103/ijo.IJO_826_17

    authors: Garg P,Kalra P,Joseph J

    更新日期:2017-11-01 00:00:00

  • Trash to treasure Retcam.

    abstract::Digital fundus imaging is being used in diagnosis, documentation, and sharing of many retinal diseases and hence forms an essential part of ophthalmology. The use of smartphones for the same has been ever increasing. There is a need for simpler devices to couple the 20D lens and smartphone so as to take fundus photogr...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_1524_18

    authors: Chandrakanth P,Ravichandran R,Nischal NG,Subhashini M

    更新日期:2019-04-01 00:00:00

  • Challenges during femtosecond laser assisted cataract surgery with posterior chamber phakic intraocular lens.

    abstract::Femtosecond laser-assisted cataract surgery was performed in a patient with high myopia, who had undergone posterior chamber phakic intraocular lens surgery (Implantable Collamer Lens, ICL). During docking the machine erroneously focused the laser on the anterior surface of ICL and laser for lens fragmentation was als...

    journal_title:Indian journal of ophthalmology

    pub_type:

    doi:10.4103/ijo.IJO_1852_18

    authors: Nath M,Gireesh P

    更新日期:2019-10-01 00:00:00

  • Pneumatic retinopexy: principles and practice.

    abstract::Pneumatic retinopexy (PR) is an alternative to scleral buckling for the surgical repair of selected retinal detachments. A gas bubble is injected into the vitreous cavity, and the patient is positioned so that the bubble closes the retinal break (s), allowing absorption of the subretinal fluid. Cryotherapy or laser ph...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:

    authors: Hilton GF,Das T,Majji AB,Jalali S

    更新日期:1996-09-01 00:00:00

  • Optimizing outcomes with toric intraocular lenses.

    abstract::Toric intraocular lenses (IOLs) are the procedure of choice to correct corneal astigmatism of 1 D or more in cases undergoing cataract surgery. Comprehensive literature search was performed in MEDLINE using "toric intraocular lenses," "astigmatism," and "cataract surgery" as keywords. The outcomes after toric IOL impl...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.4103/ijo.IJO_810_17

    authors: Kaur M,Shaikh F,Falera R,Titiyal JS

    更新日期:2017-12-01 00:00:00

  • A new device for intraocular lenses explantation.

    abstract::Intraocular lenses (IOLs) used in cataract surgery sometimes have to be explanted because of eventual complications like incorrect power, dysphotopsia, opacification, or rupture during implantation. However, current explantation procedures present several shortcomings related to the need for incision enlargement and/o...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_1171_18

    authors: Pérez-Silguero D,Rivero-Santana A

    更新日期:2019-08-01 00:00:00

  • Nematode in the retina.

    abstract::An unidentified nematode in the retina of an otherwise healthy young lady causing inflammation and exudation is reported. The worm was destroyed by Xenon photocoagulation, There was complete recovery and remarkable improvement in visual acuity. ...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Ittyerah TP

    更新日期:1990-10-01 00:00:00

  • Ocular adnexal lymphoma in the Northeast Indian population.

    abstract::We present the clinical profile of biopsy and immunohistochemistry-proven ocular adnexal lymphomas in the Northeast Indian population. Nineteen patients between October 2004 and June 2006 with ocular adnexal lymphoma were analyzed retrospectively. Histopathological classification was done according to international wo...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/0301-4738.39124

    authors: Das D,Deka P,Bhattacharjee K,Das JK,Kuri G,Deka AC,Bhattacharjee H

    更新日期:2008-03-01 00:00:00

  • Evaluation of success after second Ahmed glaucoma valve implantation.

    abstract:PURPOSE:To evaluate the outcome of the second Ahmed glaucoma valve (AGV) surgery in eyes with failed previous AGV surgery. DESIGN:Retrospective case series. PATIENTS AND METHODS:Following chart review, 36 eyes of 34 patients with second AGV implantation were enrolled in this study. The primary outcome measure was sur...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/0301-4738.181740

    authors: Nilforushan N,Yadgari M,Jazayeri AA,Karimi N

    更新日期:2016-03-01 00:00:00

  • Imiquimod 5% cream for the treatment of large nodular basal cell carcinoma at the medial canthal area.

    abstract::Context (Background): Imiquimod (IMQ) 5% cream is an immunomodulatory and antitumorigenic agent, which was used as a topical treatment regimen, who had periocular basal cell carcinoma (BCC). AIM:This study aims to present three cases with large BCC at the medial canthal area treated with IMQ 5% cream. MATERIALS AND ...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_958_16

    authors: Karabulut GO,Kaynak P,Ozturker C,Fazil K,Ocak OB,Taskapılı M

    更新日期:2017-01-01 00:00:00

  • Combined special capsular tension ring and toric IOL implantation for management of post-DALK high regular astigmatism with subluxated traumatic cataract.

    abstract::We report a case of 18-year-old male who has undergone phacoemulsification with implantation of toric IOL (AcrySof IQ SN6AT9) after fixation of lens capsule with Cionni's capsular tension ring (CTR) for subluxated traumatic cataract with high astigmatism after deep anterior lamellar keratoplasty (DALK). He underwent r...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/0301-4738.138294

    authors: Kandar AK

    更新日期:2014-07-01 00:00:00

  • Liquid crystal display microperimetry in eyes with reduced visual acuity from macular pathology.

    abstract:PURPOSE:To correlate fixation stability and retinal sensitivity measured by liquid crystal display (LCD) microperimetry to visual acuity in eyes with macular pathology. DESIGN:Retrospective chart review METHODS:The cohort included 26 eyes of 26 patients, divided into two groups according to visual acuity (Group 1 eye...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Chalam KV,Shah VA

    更新日期:2004-12-01 00:00:00

  • Infectious keratitis after transepithelial photorefractive keratectomy: A case report.

    abstract::Transepithelial photorefractive keratectomy (tPRK) promotes faster re-epithelialization which in turn can reduce the risk of infectious keratitis in the postoperative period. We present a case of a 22-year-old man with infectious keratitis in his left eye 8 days after an uneventful bilateral tPRK. A 2 mm × 5 mm anteri...

    journal_title:Indian journal of ophthalmology

    pub_type:

    doi:10.4103/ijo.IJO_1730_20

    authors: Zhuang S,Jhanji V,Sun L,Li J,Jiang J,Zhang R

    更新日期:2020-12-01 00:00:00

  • Giant eyelid eccrine hidrocystoma-induced progressive ptosis in childhood.

    abstract::An upper lid eccrine hidrocystoma presenting as early childhood progressive ptosis is very rare. We present a 9-year-old female child with droopy right upper lid since birth and progressive increase in symptoms. She had right upper lid ptosis (marginal reflex distance 1 of -1 mm) with fair levator function (8 mm) and ...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_78_17

    authors: Kumar DA,Agarwal A

    更新日期:2017-09-01 00:00:00

  • Surgically induced astigmatism and refractive outcomes following phacotrabeculectomy.

    abstract:Purpose:To objectively evaluate surgically induced astigmatism (SIA) after phacotrabeculectomy using keratometry and topography and to compare the magnitude of SIA and the refractive outcomes of single-site and twin-site phacotrabeculectomies. Methods:Forty prospective subjects were enrolled in the study and were rand...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_588_19

    authors: Senthil S,Deshmukh S,Turaga K,Pesala V,Bandela PK,Ganesh J,Garudadri C,Bharadwaj S

    更新日期:2020-04-01 00:00:00

  • Surgical technique for management of isolated lenticular coloboma with high corneal astigmatism.

    abstract::We describe a surgical technique for the correction of isolated congenital lenticular coloboma associated with high corneal astigmatism. Transscleral fixation of the capsular bag with a single eyelet Cionni capsular tension ring was followed by in-the-bag implantation of a toric intraocular lens (IOL). This lead to co...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_1026_17

    authors: Singh SR,Yangzes S,Gupta R,Ram J

    更新日期:2018-04-01 00:00:00

  • Radial keratotomy: procedures.

    abstract::The presently employed procedure of radial keratotomy is essentially unchanged from that developed by Fyodorov and introduced into the United States by Bores in 1978. The surgical procedure essentially consists of six basic steps: 1) application of appropriate anesthesia; 2) marking the visual axis; 3) marking the opt...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:

    authors: Robin JB

    更新日期:1990-07-01 00:00:00

  • Component corneal surgery: An update.

    abstract::Several decades ago, penetrating keratoplasty was a challenge to corneal surgeons. Constant effort by the corneal surgeon to improve the outcomes as well as utilization of the available resources has led to a revolutionary change in the field of keratoplasty. All these efforts have led to the evolution of techniques t...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.4103/ijo.IJO_582_17

    authors: Maharana PK,Sahay P,Singhal D,Garg I,Titiyal JS,Sharma N

    更新日期:2017-08-01 00:00:00

  • Aripiprazole-induced transient myopia: A rare entity.

    abstract::Aripiprazole is a new drug for the treatment of adults with schizophrenia. Ocular side effects of aripiprazole are very rare. Review of literature revealed few cases of aripiprazole-induced myopia. We report a rare case of aripiprazole-induced transient myopia. A 22-year-old female patient presented to the department ...

    journal_title:Indian journal of ophthalmology

    pub_type:

    doi:10.4103/ijo.IJO_907_16

    authors: Praveen Kumar KV,Chiranjeevi P,Alam MS

    更新日期:2018-01-01 00:00:00

  • Occult orbito-cranial penetrating injury by pencil: role of beta tracer protein as a marker for cerebrospinal fluid leakage.

    abstract::Orbito-cranial foreign bodies present a treacherous situation that can escape detection. The only evidence of these foreign bodies may be the entry wound in the form of a small lid laceration. A two-year-old boy presented with right upper lid laceration following a fall two hours back. Analysis of the fluid around the...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/0301-4738.86325

    authors: Shah AD,Decock C

    更新日期:2011-11-01 00:00:00

  • In vivo growth of retinoblastoma in a newborn infant.

    abstract::Retinoblastoma is a rare malignancy of the retina seen exclusively in children. It is known to cause rapid growth inside the eye and hence treatment should be started as soon as it is diagnosed. We report a case in a five-day-old infant in whom treatment (chemotherapy) was delayed by a month due to high bilirubin leve...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/0301-4738.67066

    authors: Shah PK,Narendran V,Kalpana N

    更新日期:2010-09-01 00:00:00

  • Correlation of interleukin-33 with Th cytokines and clinical severity of dry eye disease.

    abstract:PURPOSE:The purpose of this study is to determine the tear and serum protein levels of interleukin-33 (IL-33) and its correlation with Th cytokines and disease severity in dry eye (DE) syndrome. METHODS:Tear and serum samples were collected from 30 healthy volunteers, 30 DE patients with non-Sjogren's syndrome DE (NSS...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_405_17

    authors: Luo G,Xin Y,Qin D,Yan A,Zhou Z,Liu Z

    更新日期:2018-01-01 00:00:00

  • A rare case of both eyelids swelling: isolated conjunctival amyloidosis.

    abstract::Amyloid is an eosinophilic, amorphous protein that has been reported to deposit in virtually any tissue or organ and when extensive, may attain tumourous proportions. We present a rare case where both the upper and lower palpebral conjunctiva were affected by amyloid deposition. ...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Chaturvedi P,Lala M,Desai S,Sanghvi V

    更新日期:2000-03-01 00:00:00

  • Commentary: Revival of scleral buckling technique with Chandelier illumination.

    abstract:: ...

    journal_title:Indian journal of ophthalmology

    pub_type: 评论

    doi:10.4103/ijo.IJO_1964_18

    authors: Rishi E,Manchegowda PT

    更新日期:2019-03-01 00:00:00

  • Use of white light in vivo confocal microscopy for the detection of spatial changes in the corneal nerves in cases of early-stage Acanthamoeba keratitis with radial keratoneuritis.

    abstract:Purpose:Radial keratoneuritis (RK) is a common feature of Acanthamoeba keratitis (AK). In vivo confocal microscopy (IVCM) is noninvasive and provides real-time images for the diagnosis of corneal diseases by allowing the visualization of corneal structures and morphologies of living organisms at the cellular level. Ima...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/ijo.IJO_1313_19

    authors: Hung KC,Lu CJ,Liu HY,Hou YC,Wang IJ,Hu FR,Chen WL

    更新日期:2020-06-01 00:00:00

  • Comparison of ocular response analyzer parameters in primary open angle glaucoma and exfoliative glaucoma patients.

    abstract:AIM:We sought to identify differences in the following measures of the ocular response analyser (ORA) between primary open angle glaucoma (POAG) and exfoliative glaucoma (EXG) patients: Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc) and Goldmann-correlated int...

    journal_title:Indian journal of ophthalmology

    pub_type: 杂志文章

    doi:10.4103/0301-4738.138180

    authors: Beyazyıldız E,Beyazyıldız O,Arifoğlu HB,Altıntaş AK,Köklü SG

    更新日期:2014-07-01 00:00:00