Abstract:
:Chromosome homologies in reptiles have been investigated extensively by gene mapping and chromosome painting. Relative chromosome size can be estimated roughly from conventional karyotypes, but chromosome GC content cannot be evaluated by any of these approaches. However, GC content can be obtained by whole-genome sequencing, although complete data are available only for a limited number of reptilian species. Chromosomes can be characterized by size and GC content in bivariate flow karyotypes, in which the distribution of peaks represents the differences. We have analysed flow karyotypes from 9 representative squamate species and show chromosome profiles for each species based on the relationship between size and GC content. Our results reveal that the GC content of macrochromosomes is invariable in the 9 species. A higher GC content was found in microchromosomes, similar to profiles previously determined in crocodile, turtle, and chicken. The findings suggest that karyotype evolution in reptiles is characterized by unique features of chromosome GC content.
journal_name
Cytogenet Genome Resjournal_title
Cytogenetic and genome researchauthors
Kasai F,O'Brien PCM,Ferguson-Smith MAdoi
10.1159/000497265subject
Has Abstractpub_date
2019-01-01 00:00:00pages
46-52issue
1-2eissn
1424-8581issn
1424-859Xpii
000497265journal_volume
157pub_type
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