Abstract：
OBJECTIVE:To determine the incidence, risk factors and outcome of acute kidney injury (AKI) in hospitalized children with nephrotic syndrome. METHODS:All consecutive hospitalized children (aged 1-14 years) with diagnosis of nephrotic syndrome between February 2016 and February 2017 were enrolled for the study. Children (aged 1-14 years) with features of nephritis, underlying secondary causes of nephrotic syndrome as well as children admitted for diagnostic renal biopsy and intravenous cyclophosphamide or rituximab infusion were excluded. RESULTS:A total of 73 children (81 admissions) were enrolled; incidence of AKI was 16% (95% CI, 9-23). On multivariate logistic regression analysis, furosemide infusion was observed as an independent risk factor for acute kidney injury (OR 23; 95% CI, 3-141; P<0.001). Out of 13 children with AKI, three died. CONCLUSIONS:Acute kidney injury in hospitalized children with nephrotic syndrome has high risk of mortality. Children receiving furosemide infusion should be closely monitored for occurrence of acute kidney injury.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Prasad BS,Kumar M,Dabas A,Mishra Ksubject
Has Abstractpub_date
2019-02-15 00:00:00pages
119-122issue
2eissn
0019-6061issn
0974-7559journal_volume
56pub_type
杂志文章abstract：OBJECTIVE:To assess the safety and immunogenicity of a quadrivalent meningococcal (groups A,C,Y,W) polysaccharide diphtheria toxoid conjugate vaccine (MenACYW-DT) in India. DESIGN:Open-label, descriptive, non-randomized study. SETTING:Three medical college hospitals, one each in New Delhi, Bengaluru and Mumbai, India...
journal_title：Indian pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s13312-014-0435-7
更新日期：2014-06-01 00:00:00
abstract：JUSTIFICATION:Viral encephalitis is an important cause of mortality and morbidity in children. The etiological agents are varied, and physicians treating such children often feel limited by the lack of uniform guidelines on evaluation and management of these critically ill children in resource-constrained settings. PR...
journal_title：Indian pediatrics
pub_type： 杂志文章,实务指引
doi：10.1007/s13312-012-0216-0
更新日期：2012-11-01 00:00:00
abstract：:A 2-yr-old child with early onset diabetes and hypothyroidism, and diagnosed as Wolcott-Rallison Syndrome, developed two episodes of acute liver failure and recovered, but he remains at high risk of developing another episode of acute liver failure. Autoimmune, metabolic or genetic disorders should be evaluated in chi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-12-15 00:00:00
abstract：:Streptococcus viridans is usually considered to be nonpathogenic in healthy patients. Some strains become penicillin-resistant and cause life-threatening infections in immuno-compromised patients. We report an immunocompetent boy who had community-acquired S. viridans pneumonia that was resistant to penicillin. Clinic...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2012-04-01 00:00:00
abstract：:Biliary atresia has been commonly reported with cytomegalovirus (CMV) infection. CMV positive patients may present with a later onset however long term outcome is similar to non-CMV patients. There are very few case reports of role of antivirals in CMV and biliary atresia. We treated a 2 month old girl with biliary at...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0092-7
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Management of pyothorax and pneumothorax requires aspiration and/or intercostal drainage. CASE CHARACTERISTICS:We present two cases which were complicated by instrument-related events resulting in breakage of needle or intercostal drainage tube resulting in pleural foreign body. INTERVENTION/OUTCOME:The pa...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0848-6
更新日期：2016-04-01 00:00:00
abstract：:Five hundred ninety two children (6.0%) were diagnosed as persistent diarrhea (PD) out of a total attendance of 9795 cases in the Diarrhea Training and Treatment Unit (DTU) over a period of 1 year. Most of the cases were initially managed as outpatients on dietary advice and treatment of associated infections. Eighty ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:Immune thrombocytopenic purpura (ITP) has witnessed many changes and updates over the past decade. The definitions of disease subtypes, course and response to treatment have all been standardized recently. Consequent to the lack of an international consensus management guideline, wide variations exist in treatment pra...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-012-0195-1
更新日期：2012-10-01 00:00:00
abstract：:Anthropometric data from our survey of 1,879 children in Madhya Pradesh revealed low sensitivity (17.5%) and positive predictive value (30.4%) of Mid-Upper Arm Circumference (MUAC) at the recommended cut-off of 115 mm for identifying Severe Acute Malnutrition (SAM). This led us to question the reliability of MUAC as a...
journal_title：Indian pediatrics
pub_type： 信件
doi：10.1007/s13312-013-0032-1
更新日期：2013-01-08 00:00:00
abstract：:Primary immunodeficiency disorders (PIDs) are a heterogeneous group of inherited disorders that affect different components of the immune system. There are more than 150 different disorders which have been described till date. Despite major advances in the molecular characterization of PIDs over the last 20 years, man...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-013-0171-4
更新日期：2013-06-08 00:00:00
abstract：:A major purpose of the immunization coverage evaluation surveys to document the vaccination status of children aged 1-2 years was to determine the true picture of the immunization status of the target population and to identify areas which need strengthening. Immunization coverage evaluation surveys were carried out f...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:A random urine calcium/creatinine ratio (UCa/Cr) is of practical use in screening for hypercalciuria. However, due to worldwide variations, reference values for the pediatric population are not yet well established. Furthermore, no study has been conducted to establish normal UCa/Cr values in Turkish children. The obj...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:Meropenem is a new carbapenem antibacterial agent with wide spectrum of activity against gram-negative, gram-positive and anaerobic organisms. It is stable against most beta-lactamases produced by gram-negative bacteria and has greatest utility in treating severe infections in hospitalized children. It has good CSF pe...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2005-05-01 00:00:00
abstract：:Seven cases of benign form of spinal muscular atrophy were studied to evaluate the importance of detecting hand tremors, muscle fasciculation, evertion of foot and ECG tremors to distinguish these cases from muscular dystrophy. Taken in combination, diagnosis of all the seven cases was possible without the need for ap...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：OBJECTIVE:To describe the clinical profile of children with bacteriologically confirmed tuberculosis. STUDY DESIGN:A multicentric study was conducted in three hospitals in Chennai city between July 1995 and December 1997. Children aged 6 months to 12 years with signs and symptoms suggestive of tuberculosis were invest...
journal_title：Indian pediatrics
pub_type： 杂志文章,多中心研究
doi：
更新日期：2008-09-01 00:00:00
abstract：:In this retrospective study, patients with idiopathic frequently-relapsing nephrotic syndrome (FRNS) (n=27) and steroid dependent nephrotic syndrome (SDNS) (n=13) who received enteric coated mycophenolate sodium (ECMS) for at least 6 months, were included for analysis. Primary outcome was response to ECMS, which was d...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1156-5
更新日期：2017-10-15 00:00:00
abstract：:Treatment of typhoid fever with furazolidone produces a high cure rate. This is a clinical curiosity, as furazolidone is described to be poorly absorbed. The present study examined whether furazolidone could produce unequivocal clinical response and, if so whether this was due to the drug producing bactericidal levels...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：:This study is a retrospective analysis of 670 cases of poisoning (including phenothiazine toxicity) admitted to this hospital in the past six years, accounting for 0.9% of all pediatric admissions. Nearly half (45%) of the cases were in the age group of 1-4 years. Medicines and chemicals were the commonest agents (53%...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:Bone mineral content (BMC) was determined at the distal radius in 70 children aged 2-14 years; Group I comprising 34 normal healthy children and Group II 36 malnourished children by the method of single photon absorptiometry. The mean value of BMC in Group I was 0.3 +/- 0.04 g/cm in 2-5 year, 0.52 +/- 0.08 g/cm in 6-1...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
abstract：:A cross sectional study was conducted in 260 adolescent schoolchildren (114 males) in the age group of 11-18 years to estimate the prevalence of zinc deficiency in the National Capital Territory of Delhi. Serum zinc was estimated using Inductively coupled plasma mass spectrometer. Overall, 49.4% children (50.8% males,...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To document effects of intrapartum risk factors for early onset sepsis (EOS) on CRP levels in neonates and to assess the suitability of this test in diagnosing EOS. DESIGN:Cohort study. SETTING:Labour and post natal wards in a tertiary level teaching hospital in India. SUBJECTS:250 neonates at risk of deve...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：:We report a case of toxic epidermal necrolysis who was successfully treated with intravenous immunoglobin and granulocyte colony-stimulating factor. He had poor prognostic factors such as extensive epidermal loss, neutropenia, acute respiratory distress syndrome and candida sepsis, but nonetheless made a complete reco...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：:Six hundred and forty six cases in the age group 8-14 years suffering from paralytic poliomyelitis were analysed to find out the immunization status and its correlation with the incidence of poliomyelitis. In 382 cases where the immunization status was known, it was found that 325 (85.02%) cases were not immunized, 23...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVE:To evaluate recovery and survival of severely wasted children without community management of acute malnutrition programme. DESIGN:Single time point follow-up (24th December 2013 - 2nd April, 2014) of severely wasted children identified in a community-based cross-sectional survey (September 2012 - October 20...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1142-y
更新日期：2017-10-15 00:00:00
abstract：OBJECTIVES:To evaluate whether zinc supplements prevent mortality and morbidity in breastfed low birth weight infants. METHODS:All randomized or qausi-randomized trials with individual or cluster allocation and using concurrent controls were included. Study population included LBW infants irrespective of gestational s...
journal_title：Indian pediatrics
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s13312-011-0043-8
更新日期：2011-02-01 00:00:00
abstract：NEED AND PURPOSE OF REVIEW:A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA:MEDLINE search ...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-013-0284-9
更新日期：2013-11-08 00:00:00
abstract：:We report a 6 year old female child, who presented with history of right sided recurrent headache for four months. On diagnostic nasal endoscopy, a metallic foreign body was seen impacted between superior turbinate, middle turbinate and nasal septum which was removed using pediatric nasal endoscope. Following removal,...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:GM1 gangliosidosis is a disorder due to GLB1 gene mutation. CASE CHARACTERISTICS:A 4-yr-old boy with neuroregression and optic atrophy with periventricular hyperintensity on magnetic resonance imaging. OUTCOME:Beta galactosidase enzyme activity was low which was confirmed by GLB1 sequencing. MESSAGE:We hi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0593-2
更新日期：2015-02-01 00:00:00
abstract：:Youth violence is a growing problem worldwide. Research on adolescent violence in India is limited. Fifteen hundred high school students were investigated to study the prevalence and demographic characteristics of witnesses, victims and perpetrators of violence and to see the impact of violence exposure on their psych...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the short term clinical effects of delayed cord clamping in preterm neonates. DESIGN:Randomized controlled trial. SETTING:A tertiary care neonatal unit from October 2013 to September 2014. PARTICIPANTS:78 mothers with preterm labor between 27 to 316/7 weeks gestation. INTERVENTION:Early cord c...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s13312-017-1011-8
更新日期：2017-02-15 00:00:00
