Mycophenolate Sodium for Children with Frequently Relapsing or Steroid Dependent Nephrotic Syndrome.

Abstract:

:In this retrospective study, patients with idiopathic frequently-relapsing nephrotic syndrome (FRNS) (n=27) and steroid dependent nephrotic syndrome (SDNS) (n=13) who received enteric coated mycophenolate sodium (ECMS) for at least 6 months, were included for analysis. Primary outcome was response to ECMS, which was defined as complete if there were no relapses, partial response if there was 1 relapse and no response if there were 2 or more relapses within 6 months of initiation. The mean (SD) dose of ECMS was 985.24 (190.82) mg/m2/day. Thirty patients(75%) had complete response, eight (20%) had partial and two (5%) patients did not respond at 6 months. ECMS seems to be a safe and effective as steroid sparing agent in children with FRNS/SDNS.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Kapoor K,Saha A,Kaur M,Dubey NK,Upadhyay AD

doi

10.1007/s13312-017-1156-5

subject

Has Abstract

pub_date

2017-10-15 00:00:00

pages

885-886

issue

10

eissn

0019-6061

issn

0974-7559

journal_volume

54

pub_type

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