Abstract:
:Helicobacter pylori is a human pathogenic bacterium with a high genomic plasticity. Although the functional CRISPR-Cas system has not been found in its genome, CRISPR-like loci have been recently identified. In this work, 53 genomes from different geographical areas are analyzed for the search and analysis of variability of this type of structure. We confirm the presence of a locus that was previously described in the VlpC gene in al lgenomes, and we characterize new CRISPR-like loci in other genomic locations. By studying the variability and gene location of these loci, the evolution and the possible roles of these sequences are discussed. Additionally, the usefulness of this type of sequences as a phylogenetic marker has been demonstrated, associating the different strains by geographical area.
journal_name
PeerJjournal_title
PeerJauthors
García-Zea JA,de la Herrán R,Robles Rodríguez F,Navajas-Pérez R,Ruiz Rejón Cdoi
10.7717/peerj.6221subject
Has Abstractpub_date
2019-01-11 00:00:00pages
e6221issn
2167-8359pii
6221journal_volume
7pub_type
杂志文章相关文献
PeerJ文献大全abstract::Equine Herpesviruses (EHV) are common and often latent pathogens of equids which can cause fatalities when transmitted to non-equids. Stress and elevated glucocorticoids have been associated with EHV reactivation in domestic horses, but little is known about the correlation between stress and viral reactivation in wil...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5422
更新日期:2018-08-22 00:00:00
abstract:OBJECTIVE:To determine the profile of 14 polybrominated diphenyl ethers (PBDEs) and 23 polychlorinated biphenyls (PCBs) in serum of domestic canines and whether this was predictive of thyroid hormone status. SAMPLES:Serum samples were collected from 51 client-owned dogs visiting the University of California Davis Will...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3780
更新日期:2017-09-12 00:00:00
abstract:Background:Electrochemical signals play an important role in cell communication and behavior. Electrically charged ions transported across cell membranes maintain an electrochemical imbalance that gives rise to bioelectric signaling, called membrane potential or Vmem. Vmem plays a key role in numerous inter- and intrac...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6341
更新日期:2019-02-08 00:00:00
abstract:Background:In idiopathic sudden sensorineural hearing loss (ISSNHL), the relationship between the administration duration of vitamin B12 (vit B12) with adenosine triphosphate (ATP) and their therapeutic effect is not fully understood. Objective:To investigate the therapeutic effect of long-term 16 (≥weeks) administrat...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10406
更新日期:2020-12-16 00:00:00
abstract:BACKGROUND:Several recent studies have shown that total scores on depressive symptom measures in a general population approximate an exponential pattern except for the lower end of the distribution. Furthermore, we confirmed that the exponential pattern is present for the individual item responses on the Center for Epi...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2987
更新日期:2017-02-09 00:00:00
abstract::A fundamental question in ecology is how the success of a taxon changes through time and what drives this change. This question is commonly approached using trajectories averaged over a group of taxa. Using results from probability theory, we show analytically and using examples that averaged trajectories will be more...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8011
更新日期:2019-11-06 00:00:00
abstract:Background:Acipenser dabryanus, an endemic Chinese species, has been listed as a first-class protected animal in China. Sturgeons are among the oldest and most primitive group of existing fish in the world and occupy a special place in the evolutionary history of fish. Thus, a study of the reproduction and sex differen...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5389
更新日期:2018-07-27 00:00:00
abstract:Background:Simao pine (Pinus kesiya Royle ex Gordon var. langbianensis (A. Chev.) Gaussen) is one of the most important tree species in the production of timber and resin in China. However, the genetic diversity of the natural populations has not been assessed to date. In this study, sequence related amplified polymorp...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6529
更新日期:2019-02-26 00:00:00
abstract::We studied the impact of simulated global change on a high alpine meadow plant community. Specifically, we examined whether short-term (5 years) responses are good predictors for medium-term (7 years) changes in the system by applying a factorial warming and nutrient manipulation to 20 plots in Latnjajaure, subarctic ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.406
更新日期:2014-05-22 00:00:00
abstract:BACKGROUND:Rare or narrowly endemic organisms are difficult to monitor and conserve when their total distribution and habitat preferences are incompletely known. One method employed in determining distributions of these organisms is species distribution modeling (SDM). METHODS:Using two species of narrowly endemic bur...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3632
更新日期:2017-07-31 00:00:00
abstract:Aim:We aimed to translate and cross-culturally adapt the International Knee Documentation Committee-subjective knee form (IKDC) in Romanian. Method:The original (US) IKDC-subjective knee form was translated according to recommended guidelines. Validity was tested using Spearmans's correlation coefficient between score...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.8448
更新日期:2020-02-03 00:00:00
abstract::Introduction. Colorectal cancer is one of the most frequent cancers in the world and liver metastases are seen in up to 19% of patients with colorectal cancers. Detection of liver metastases is not only vital for sufficient treatment and survival, but also for a better estimation of prognosis. The aim of this study wa...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1532
更新日期:2016-01-14 00:00:00
abstract::Recent upperward migration of plants and animals along altitudinal gradients and poleward movement of animal range boundaries have been confirmed by many studies. This phenomenon is considered to be part of the fingerprint of recent climate change on the biosphere. Here I examine whether poleward movement is occurring...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.77
更新日期:2013-05-28 00:00:00
abstract::A feeding trial was conducted to assess the feasibility of supplementing taurine in soy-based diets for juvenile starry flounder Platichthys stellatus. The basal diet (Crude protein 66.5%, crude lipid 8.5%) was supplemented with 0 (control), 0.5%, 1.0%, 1.5%, 2.0% and 2.5% taurine to formulate six test diets. Each die...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.10597
更新日期:2021-01-11 00:00:00
abstract::Aedes aegypti is the major vector of dengue, yellow fever and chikungunya viruses that put millions of people in endemic countries at risk. Mass rearing of this mosquito is crucial for strategies that use modified insects to reduce vector populations and transmission of pathogens, such as sterile insect technique or p...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.938
更新日期:2015-05-05 00:00:00
abstract:BACKGROUND:Staphylococci are commensals of the mucosal surface and skin of humans and animals, but have been implicated in infections such as otitis externa, pyoderma, urinary tract infections and post-surgical complications. Laboratory records provide useful information to help investigate these infections. Therefore,...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3198
更新日期:2017-04-13 00:00:00
abstract::The prevalence of pre-diabetes (PD) among US adults has increased substantially over the past two decades. By current estimates, over 34% of US adults fall in the PD category, 84% of whom meet the American Diabetes Association's criteria for impaired fasting glucose (IFG). Low physical activity (PA) and/or sedentary b...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.499
更新日期:2014-08-19 00:00:00
abstract::Vitellogenin has been proposed to regulate division of labor and social organization in social insects. The red imported fire ant (Solenopsis invicta) harbors four distinct, adjacent vitellogenin genes (Vg1, Vg2, Vg3, and Vg4). Contrary to honey bees that have a single Vg ortholog as well as potentially fertile nurses...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.4875
更新日期:2018-05-28 00:00:00
abstract::As other spiny lobsters, Panulirus argus is supposed to use preferentially proteins and lipids in energy metabolism, while carbohydrates are well digested but poorly utilized. The aim of this study was to evaluate the effect of dietary carbohydrate level on digestion and metabolism in the spiny lobster P. argus. We us...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3975
更新日期:2017-11-03 00:00:00
abstract::Although mosquito microbiota are known to influence reproduction, nutrition, disease transmission, and pesticide resistance, the relationship between host-associated microbial community composition and geographical location is poorly understood. To begin addressing this knowledge gap, we characterized microbiota assoc...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6168
更新日期:2019-01-09 00:00:00
abstract:Background:Mimusops coriacea (A.DC.) Miq., (Sapotaceae), originated from Africa, were introduced to coastal areas in Ecuador where it is not extensively used as a traditional medicine to treat various human diseases. Different therapeutically uses of the species include: analgesic, antimicrobial, hypoglycemic, inflamma...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.7789
更新日期:2019-10-11 00:00:00
abstract::Language WorkBenches (LWBs) are software engineering tools that help domain experts develop solutions to various classes of problems. Some of these tools focus on non-technical users and provide languages to help organize knowledge while other workbenches provide means to create new programming languages. A key advant...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.241
更新日期:2014-01-02 00:00:00
abstract:INTRODUCTION:The aim of this study was to determine the incidence rates of endometrial hyperplasia (EH) and endometrial cancer (EC) in the Republic of Korea using national insurance claim data generated from 2009 to 2012. MATERIALS AND METHODS:Data that were generated from 2009 to 2012 were sourced from the Korean Hea...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2374
更新日期:2016-08-24 00:00:00
abstract::Crop landraces are fundamental resources to increase the eroded genepool of modern crops in order to adapt agriculture to future challenges; plus, they are of immeasurable heritage and cultural value. Between the 1940s and the 1960s open-pollinated varieties (OPVs) of flint and semi-flint maize in Europe were almost c...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5123
更新日期:2018-07-04 00:00:00
abstract:Background:Mangroves are important coastal ecosystems known for high photosynthetic productivity and the ability to support marine food chains through supply of dissolved carbon or particular organic matter. Most of the carbon found in mangroves is produced by its vegetation and is decomposed in root associated sedimen...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.5710
更新日期:2018-10-04 00:00:00
abstract::We examined whether chemically mediated risk perception by prey and the effects of changes in prey behavior on basal resources vary as a function of the amount of prey biomass consumed by the predator. We studied these issues using a tritrophic system composed of blue crabs, Callinectes sapidus (top predator), mud cra...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.1426
更新日期:2015-11-19 00:00:00
abstract::Although the existence of coral-reef habitats at depths to 165 m in tropical regions has been known for decades, the richness, diversity, and ecological importance of mesophotic coral ecosystems (MCEs) has only recently become widely acknowledged. During an interdisciplinary effort spanning more than two decades, we c...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.2475
更新日期:2016-10-04 00:00:00
abstract:BACKGROUND:The scholarly publication landscape is changing rapidly. We investigated whether the introduction of an institutional publications officer might help facilitate better knowledge of publication topics and related resources, and effectively support researchers to publish. METHODS:In September 2015, a purpose-...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.3294
更新日期:2017-05-31 00:00:00
abstract::Engaging in effortful self-control can sometimes impair people's ability to resist subsequent temptations. Existing research has shown that when chronic dieters' self-regulatory capacity is challenged by prior exertion of effort, they demonstrate disinhibited eating and altered patterns of brain activity when exposed ...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.6550
更新日期:2019-02-28 00:00:00
abstract::Previous studies of population genetic structure in Dissostichus eleginoides have shown that oceanographic and geographic discontinuities drive in this species population differentiation. Studies have focused on the genetics of D. eleginoides in the Southern Ocean; however, there is little knowledge of their genetic v...
journal_title:PeerJ
pub_type: 杂志文章
doi:10.7717/peerj.4173
更新日期:2018-01-16 00:00:00