Bronchial asthma: pathophysiological mechanisms and corticosteroids.

abstract：BACKGROUND:While total IgE measurements are often used in clinical practice, it is unclear how they should be interpreted for the diagnosis of allergic disorders. We studied whether total IgE may be used to rule out or predict sensitization and whether there are age or gender differences. METHODS:ROC curves were asses...

journal_title：Allergy

authors： Kerkhof M,Dubois AE,Postma DS,Schouten JP,de Monchy JG

更新日期：2003-09-01 00:00:00

abstract：:Skin tests and estimation of specific IgE-antibodies by the RAST are evaluated as diagnostic procedures in bee sting hypersensitivity with the followiny extracts. (2) With bee venom results of skin tests and RAST correspond in 82%, with bee wholebody extracts in 68%. (3) Both with skin tests and the RAST with bee veno...

journal_title：Allergy

authors： Patrizzi R,Müller U,Yman L,Hoigné R

更新日期：1979-08-01 00:00:00

abstract：:The present study was designed to investigate the effects of immunotherapy (IT) with an extract of Dermatophagoides pteronyssinus (Alergo-Merck Depot) during a 27-month period in patients with allergic asthma to house-dust mites. We included 11 patients (mean age 18 years) treated with a combination of IT and inhaled ...

journal_title：Allergy

authors： Costa JC,Plácido JL,Silva JP,Delgado L,Vaz M

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Polcalcins are pollen-specific allergens with two EF-hand calcium-binding sites that exhibit strong cross-reactivity. Our objective was to isolate and express the cDNA coding of the EF-hand calcium-binding allergen from lilac pollen and to study cross-reactivity with other polcalcins from related and nonrela...

journal_title：Allergy

authors： Ledesma A,Barderas R,Westritschnig K,Quiralte J,Pascual CY,Valenta R,Villalba M,Rodríguez R

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Budesonide/formoterol (Symbicort) Maintenance and Reliever Therapy (SMART) is an effective asthma-management approach that treats symptoms with rapid increases in budesonide/formoterol. The cost-effectiveness of SMART vs higher fixed-dose budesonide/formoterol or salmeterol/fluticasone is unknown. METHODS:T...

journal_title：Allergy

authors： Price D,Wirén A,Kuna P

更新日期：2007-10-01 00:00:00

abstract：:Nonallergic non-infectious perennial rhinitis (NANIPER) is a heterogeneous disorder comprising several pathophysiological entities. The etiology of some of these disorders (e.g. drug-induced rhinitis, nonallergic rhinitis with eosinophilia syndrome [NARES], occupational rhinitis, hormonal rhinitis, emotion-induced rhi...

journal_title：Allergy

authors： Garay R

更新日期：2004-01-01 00:00:00

abstract：:Antibody-dependent, allergic autocytotoxicity (ACT) is an in vitro process through which WBC from patients and/or controls, passively sensitized with RAST positive serum, are damaged in the presence of corresponding food antigens. Studies among 13 patients, sensitive to cow milk, corn and wheat, and 13 asymptomatic co...

journal_title：Allergy

authors： Podleski WK

更新日期：1985-04-01 00:00:00

abstract：:The incidence of positive skin test responses among atopic subjects with suspected respiratory allergy was investigated with commercial and autochthonous pollen extracts of various cultivars of Olea europaea. Pollen was collected from olive trees of well-defined cultivars, extracted, and separated by SDS-PAGE. Immunob...

journal_title：Allergy

authors： Waisel Y,Geller-Bernstein C,Keynan N,Arad G

更新日期：1996-11-01 00:00:00

abstract：:The leading priority for the Polish Presidency of the Council of the European Union was to reduce health inequalities across European societies, and, within its framework, prevention and control of respiratory diseases in children. This very important paper contain proposal of international cooperation on the preventi...

journal_title：Allergy

authors： Samoliński B,Fronczak A,Kuna P,Akdis CA,Anto JM,Bialoszewski AZ,Burney PG,Bush A,Czupryniak A,Dahl R,Flood B,Galea G,Jutel M,Kowalski ML,Palkonen S,Papadopoulos N,Raciborski F,Sienkiewicz D,Tomaszewska A,Von Mutius

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Analyses of exhaled volatile organic compounds (VOCs) have shown promising results when distinguishing individuals with asthma. Currently, there are no biomarkers for uncontrolled asthma. Therefore, we aimed to assess, in a real-life clinical setting, the ability of the exhaled VOC analysis, using an electro...

journal_title：Allergy

authors： Farraia M,Cavaleiro Rufo J,Paciência I,Castro Mendes F,Rodolfo A,Rama T,Rocha SM,Delgado L,Brinkman P,Moreira A

更新日期：2020-07-01 00:00:00

abstract：:Airway remodeling is a central feature of asthma. It is exemplified by thickening of the lamina reticularis and structural changes to the epithelium, submucosa, smooth muscle, and vasculature of the airway wall. Airway remodeling may result from persistent airway inflammation. Immunoglobulin E (IgE) is an important me...

journal_title：Allergy

authors： Rabe KF,Calhoun WJ,Smith N,Jimenez P

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Previous US population-based epidemiologic studies of anaphylactic deaths have been limited by small populations and/or few deaths. The objective of this study was to determine the 10-year incidence of death from anaphylaxis in Florida and its descriptive epidemiology. METHODS:Patients who died from anaphyl...

journal_title：Allergy

authors： Simon MR,Mulla ZD

更新日期：2008-08-01 00:00:00

abstract：:Quantitative risk assessment (QRA) for food allergens has made considerable progress in recent years, yet acceptability of its outcomes remains stymied because of the limited extent to which it has been possible to incorporate severity as a variable. Reaction severity, particularly following accidental exposure, depen...

journal_title：Allergy

authors： Dubois AEJ,Turner PJ,Hourihane J,Ballmer-Weber B,Beyer K,Chan CH,Gowland MH,O'Hagan S,Regent L,Remington B,Schnadt S,Stroheker T,Crevel RWR

更新日期：2018-07-01 00:00:00

abstract：:Twenty patients with severe or medium severe asthma were given atenolol (Atenol ICI-Pharma) and/or metoprolol (Seloken Hässle) for tachycardia, hyperkinetic tremor, arterial hypertension or symptoms of angina pectoris. These cardioselective beta-blocking drugs caused only a very slight decrease in PF values. There was...

journal_title：Allergy

authors： Carlson C,Järvinen KA

更新日期：1978-06-01 00:00:00

abstract：:The aim of this study was to assess the ability of the H1-receptor antagonist loratadine to modify anti-IgE-induced cutaneous wheal-and-flare and late-phase reactions (WFR and LPR), as well as histamine release and leukocyte accumulation in skin chambers. For this purpose, 10 atopics with allergic rhinitis were entere...

journal_title：Allergy

authors： Roquet A,Raud J,Halldén G,van Hage-Hamsten M,Hed J,Hansson LO,Zetterström O,Grönneberg R

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:We hypothesized that, in south-west Poland, a 'rural' protective effect on atopy and respiratory allergies would be most pronounced among children but that at all ages would be stronger among those with a rural background. METHODS:A cross-sectional survey of the inhabitants (age >5 years, n = 1657) of Sobot...

journal_title：Allergy

authors： Sozanska B,Macneill SJ,Kajderowicz-Kowalik M,Danielewicz H,Wheatley M,Newman Taylor AJ,Boznanski A,Cullinan P

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Epidemiologic data on asthma and allergies among adults are mainly based on questionnaires: this study validates the questions on asthma, allergic rhinitis, and conjunctivitis of a new Finnish questionnaire. METHODS:To validate questions used in a country-wide study among university students aged 18-25 year...

journal_title：Allergy

authors： Kilpeläinen M,Terho EO,Helenius H,Koskenvuo M

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Given the key role of interleukin-5 (IL-5) in eosinophil function, we investigated the regulated expression of the membrane-anchored (TM-IL-5Ralpha) isoform, or a secreted (SOL IL-5Ralpha) isoform, on both protein and transcript level in vitro and in vivo. METHODS:A real-time PCR, FACS and ELISA were establ...

journal_title：Allergy

authors： Gevaert P,Hellman C,Lundblad L,Lundahl J,Holtappels G,van Cauwenberge P,Tavernier J,Bachert C

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Adolescence represents a vulnerable time for individuals with asthma and allergic conditions. They suffer an unexpected degree of morbidity. This systematic review aimed to understand the challenges faced by adolescents and young adults with these conditions. METHODS:A systematic literature search was under...

journal_title：Allergy

authors： Vazquez-Ortiz M,Angier E,Blumchen K,Comberiati P,Duca B,DunnGalvin A,Gore C,Hox V,Jensen B,Pite H,Santos AF,Sanchez S,Alviani C,Garriga-Baraut T,Knibb R,Mortz CG,Gowland MH,Timmermans F,Roberts G

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The Coronavirus disease 2019 (COVID-19) has evolved as a pandemic infectious disease transmitted by the severe acute respiratory syndrome coronavirus (SARS-CoV-)2. Allergists and other health care providers (HCPs) in the field of allergies and associated airway diseases are in the front line, taking care of ...

journal_title：Allergy

authors： Pfaar O,Klimek L,Jutel M,Akdis CA,Bousquet J,Breiteneder H,Chinthrajah S,Diamant Z,Eiwegger T,Fokkens WJ,Fritsch HW,Nadeau KC,O'Hehir RE,O'Mahony L,Rief W,Sampath V,Schedlowski M,Torres M,Traidl-Hoffmann C,Wang DY,

更新日期：2020-06-12 00:00:00

abstract：:Intramuscular adrenaline is the gold standard treatment for anaphylaxis. Intramuscular injection provides more rapid and higher plasma concentrations than subcutaneous routes. Given the increasing epidemic of obesity patients are at increased risk of subcutaneous delivery, we therefore assessed the depth of subcutaneo...

journal_title：Allergy

authors： Johnstone J,Hobbins S,Parekh D,O'Hickey S

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Jackfruit allergy has been reported just once. It is unknown whether this food allergy is caused by direct sensitization or cross-sensitization to pollen allergens. OBJECTIVE:Establish whether jackfruit allergy is linked to birchpollen allergy. METHODS:Two jackfruit allergic patients and five patients with...

journal_title：Allergy

authors： Bolhaar ST,Ree R,Bruijnzeel-Koomen CA,Knulst AC,Zuidmeer L

更新日期：2004-11-01 00:00:00

abstract：:The frequency of aspirin intolerance by history in 2,592 normal individuals was 0.3%. Although the frequency of aspirin intolerance was similar in adults and children, the bronchospastic type predominated in adults, and only the urticarial type was found in normal children. The frequency of recurrent urticaria, regar...

journal_title：Allergy

authors： Settipane RA,Constantine HP,Settipane GA

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:We have previously demonstrated the presence of toll-like receptor 9 in the nasal mucosa of both healthy and allergic individuals. CpG motifs, found in bacterial and viral DNA, elicit strong immunostimulatory effects via this receptor. CpG is known to skew the immune system towards a T helper 1 (Th1) profile...

journal_title：Allergy

authors： Månsson A,Bachar O,Adner M,Cardell LO

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The capacity of inflammatory cells to adhere involves an array of adhesion molecules, and is critical to the inflammatory responses seen in childhood asthma. We aimed to determine the changes of intercellular adhesion molecule-1 (ICAM-1) and L-selectin expressed on peripheral blood (PB) T lymphocytes and nat...

journal_title：Allergy

authors： Lin SJ,Chang LY,Yan DC,Huang YJ,Lin TJ,Lin TY

更新日期：2003-01-01 00:00:00

abstract：:Oral immunotherapy (IT) was evaluated in a pilot study in two centres in children aged 8-15 years with allergic rhinoconjunctivitis. High doses (up to 20 X 10(6) BU monthly) of a defined freeze-dried birch pollen extract administered in enteric-coated gelatine capsules were given either daily for seven consecutive day...

journal_title：Allergy

authors： Björkstén B,Möller C,Broberger U,Ahlstedt S,Dreborg S,Johansson SG,Juto P,Lanner A

更新日期：1986-05-01 00:00:00

abstract：:Asthma deaths are uncommon, but have recently increased in some countries due to problems in the management of the disease. Morbidity rates show large variations, which can be attributed to differences in defining the disease, but also to genuine variations, with a trend towards less asthma in northern Europe. It has ...

journal_title：Allergy

authors： Charpin D,Vervloet D,Charpin J

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Some patients with allergic asthma treated with anti-IgE (Xolair) do not become symptom free. Better criteria for response assessment than allergy skin tests or IgE determination are needed. The impact of the size of the disease relevant allergen-specific IgE antibody fraction, i.e. the percentage of IgE ant...

journal_title：Allergy

authors： Johansson SG,Nopp A,Oman H,Ankerst J,Cardell LO,Grönneberg R,Matsols H,Rudblad S,Strand V,Stålenheim G

更新日期：2009-10-01 00:00:00

abstract：:The mite fauna in hay dust of 16 farms located on the island of Gotland was analysed to establish whether there is a clear relationship between environmental exposure to storage mites and development of allergic symptoms. Eight of these farms belonged to farmers with respiratory symptoms related to barn dust (RS) and ...

journal_title：Allergy

authors： van Hage-Hamsten M,Johansson E,Wirén A,Johansson SG

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Alkaline serine proteases from six prevalent airborne Penicillium and Aspergillus species have been identified as a group of major allergens (group 13). After entering human airways, the allergens are in initial contacts with respiratory epithelial cells. The purpose of this study is to investigate interacti...

journal_title：Allergy

authors： Tai HY,Tam MF,Chou H,Peng HJ,Su SN,Perng DW,Shen HD

更新日期：2006-03-01 00:00:00